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International Forum of Allergy &... Feb 2013The purpose of this work was to perform a systematic review regarding ossifying fibroma and its multiple variants of the paranasal sinuses, and to identify any clinical... (Review)
Review
BACKGROUND
The purpose of this work was to perform a systematic review regarding ossifying fibroma and its multiple variants of the paranasal sinuses, and to identify any clinical differences between the multiple variants.
METHODS
A search of the U.S. National Library of Medicine (PubMed) database was performed for the non–Medical Subject Heading (MeSH) search term “ossifying fibroma.” The bibliographies of the retrieved manuscripts were searched to identify additional potentially relevant articles. Finally, textbooks of head and neck pathology were searched to identify peer-reviewed literature that addresses the histopathology of ossifying fibroma and its variants. Abstracts were screened by 2 of the authors to identify reports of ossifying fibroma lesions (and its variants) that involved the paranasal sinuses. Extracted data from case reports or case series included the clinical presentation, age, gender, site of involvement, surgical approach, treatment outcome, follow-up period, and recurrence rate. Information derived from cases is summarized in tables, and simple descriptive statistics were applied to the data.
RESULTS
A total of 137 distinct patients were identified in 103 reports. Extracted data did not show any appreciable difference in clinical presentation or outcomes. Data on recurrence of these lesions was often limited by a lack of follow-up.
CONCLUSION
Although differentiation between the subtypes of ossifying fibroma can be made histologically, and a diverse nomenclature exists, there does not appear to be any overriding clinical significance to the histopathologic differentiation of OF variants.
Topics: Bone Neoplasms; Fibroma, Ossifying; Humans; Nasal Cavity; Nose Neoplasms; Paranasal Sinus Neoplasms; Tomography, X-Ray Computed; Treatment Outcome
PubMed: 22736440
DOI: 10.1002/alr.21067 -
Polish Journal of Pathology : Official... 2021Juvenile psammomatoid ossifying fibroma (JPOF) is an uncommon benign and locally aggressive tumor. We report an unusual head tumour with extremely rare extensiveness and...
Juvenile psammomatoid ossifying fibroma (JPOF) is an uncommon benign and locally aggressive tumor. We report an unusual head tumour with extremely rare extensiveness and aggressivness. The patient was 18-year-old female with three-day-lasting headache and repetitive oral bleeding. Computed tomography revealed a large, well-circumscribed, expansile mass occupying ethmoid cells, nasal cavities and ventral part of the sphenoid sinus, with extention into the anterior cranial fossa. Pterional craniotomy was carried out. On one-year follow-up recurrence of the lesion was identified and the second surgery was performed. The lesion is under supervision now, due to incomplete removal.
Topics: Adolescent; Bone Neoplasms; Female; Fibroma, Ossifying; Humans; Tomography, X-Ray Computed
PubMed: 35048642
DOI: 10.5114/pjp.2021.111779 -
Seminars in Diagnostic Pathology Nov 1999Cementum is a calcified dental tissue that covers the roots of teeth and is part of the periodontium. Its function is to help anchor the teeth in their sockets within... (Review)
Review
Cementum is a calcified dental tissue that covers the roots of teeth and is part of the periodontium. Its function is to help anchor the teeth in their sockets within the alveolar bone of the jaws. Two benign mesenchymal odontogenic tumors are uniquely distinguished by elaboration of cementum or cementum-like material: cemento-ossifying fibroma and benign cementoblastoma (true cementoma). Cemento-ossifying fibroma, which is also termed periodontoma, is characterized by production of cementum and bone in a fibrous stroma. It is a painless, slow-growing tumor usually detected in the third and fourth decade of life and is more common in women. The mandible is its site of predilection. Benign cementoblastoma is intimately associated with the roots of teeth, most commonly mandibular molars. It affects young patients, usually under the age of 20 years. Pain is a common symptom in addition to bone expansion. Benign cementoblastoma bears considerable histologic resemblance to osteoblastoma.
Topics: Adolescent; Adult; Dental Cementum; Female; Fibroma, Ossifying; Humans; Jaw Neoplasms; Male; Odontogenic Tumors
PubMed: 10587273
DOI: No ID Found -
Child's Nervous System : ChNS :... Oct 2021Ossifying fibroma (OF) is an uncommon benign fibro-osseous lesion. Based on its clinical, morphological, and radiological features, OF is further divided into... (Review)
Review
Ossifying fibroma (OF) is an uncommon benign fibro-osseous lesion. Based on its clinical, morphological, and radiological features, OF is further divided into cemento-ossifying fibroma (COF), juvenile psammomatoid ossifying fibroma (JPOF), and juvenile trabecular ossifying fibroma (JTOF). JPOF rarely involves the cranial base, with limited reports published on spheno-orbital JPOF. In this paper, we report a case of JPOF of the greater wing of the sphenoid bone and lateral orbital wall in an 11-year-old child and show a surgical video. Although rare, JPOF should be considered in the differential diagnosis of fibro-osseous lesions of the spheno-orbital region.
Topics: Bone Neoplasms; Child; Diagnosis, Differential; Fibroma, Ossifying; Humans; Radiography; Sphenoid Bone
PubMed: 33404728
DOI: 10.1007/s00381-020-05004-8 -
Oral Oncology Feb 2021
Topics: Adolescent; Adult; Aged; Cementoma; Child; Child, Preschool; Female; Fibroma, Ossifying; Humans; Infant; Male; Middle Aged; Young Adult
PubMed: 33129707
DOI: 10.1016/j.oraloncology.2020.105050 -
BMJ Case Reports Dec 2020Ossifying fibroma (OF) is a rare, benign, fibro-osseous lesion of the jawbone characterised by replacement of the normal bone with fibrous tissue. The fibrous tissue...
Ossifying fibroma (OF) is a rare, benign, fibro-osseous lesion of the jawbone characterised by replacement of the normal bone with fibrous tissue. The fibrous tissue shows varying amount of calcified structures resembling bone and/or cementum. The central variant of OF is rare, and shows predilection for mandible among the jawbone. Although it is classified as fibro-osseous lesion, it clinically behaves as a benign tumour and can grow to large size, causing bony swelling and facial asymmetry. This paper reports a case of large central OF of mandible in a 40-year-old male patient. The lesion was treated by segmental resection of mandible. Reconstruction of the surgical defect was done using avascular fibula bone graft. Role of three-dimensional printing of jaw and its benefits in surgical planning and reconstruction are also highlighted.
Topics: Adult; Facial Asymmetry; Fibroma, Ossifying; Fibula; Humans; Imaging, Three-Dimensional; Jaw; Male; Mandibular Neoplasms; Orthognathic Surgical Procedures; Printing, Three-Dimensional; Tomography, X-Ray Computed
PubMed: 33372024
DOI: 10.1136/bcr-2020-239286 -
BMJ Case Reports May 2013Peripheral ossifying fibroma is a gingival growth, usually arising from interdental papilla and occurring frequently in the anterior maxilla. It represents upto 2% of...
Peripheral ossifying fibroma is a gingival growth, usually arising from interdental papilla and occurring frequently in the anterior maxilla. It represents upto 2% of all lesions that are biopsied. Other terms used to describe this lesion include peripheral ossifying fibroma, peripheral cementifying fibroma and calcified or ossified fibrous epulis. Paediatric patients with such a lesion have special management considerations as it requires early recognition and treatment. It requires proper treatment protocol with close postoperative follow-up. This case report presents a 12-year-old boy with an unusually large lesion in relation to the palatal aspect of the maxillary anterior teeth and its management.
Topics: Child; Fibroma, Ossifying; Gingival Neoplasms; Humans; Male; Maxillary Neoplasms
PubMed: 23696140
DOI: 10.1136/bcr-2013-009010 -
Journal of the Massachusetts Dental... 2015
Topics: Adult; Age Factors; Diagnosis, Differential; Female; Fibroma, Ossifying; Humans; Mandibular Neoplasms; Radiography; Sex Factors
PubMed: 26727817
DOI: No ID Found -
Oral Surgery, Oral Medicine, Oral... Aug 2012The purpose of this study was to evaluate the clinical outcomes of ossifying fibroma (OF) in a group of 14 patients treated in our clinic and discuss the management and... (Review)
Review
OBJECTIVE
The purpose of this study was to evaluate the clinical outcomes of ossifying fibroma (OF) in a group of 14 patients treated in our clinic and discuss the management and the prognosis of this tumor.
STUDY DESIGN
The study included 14 consecutive patients with OF of the jaws with ages ranging from 7 to 55 years. Primary site distribution was maxilla (1), maxilla, maxillary sinus (1), and mandible (12). All of the patients treated by surgery (curettage, enucleation, or radical surgery).
RESULTS
The mean follow-up range was 2-18 years. All of the patients were alive and disease free.
CONCLUSIONS
OF is a benign slow-growing tumor of the jaws. Early tumors that are small or well demarcated are treated by curettage or enucleation. For aggressive tumors that show rapid enlargement, radical resection (maxillectomy or segmental mandibulectomy) is used. By either method of treatment, the recurrence rate is extremely low.
Topics: Adolescent; Adult; Child; Diagnosis, Differential; Disease-Free Survival; Female; Fibroma, Ossifying; Follow-Up Studies; Humans; Jaw Neoplasms; Male; Middle Aged; Radiography, Panoramic; Tomography, X-Ray Computed; Young Adult
PubMed: 22776732
DOI: 10.1016/j.tripleo.2011.07.033 -
Stomatologija 2021Peripheral ossifying fibroma (POF) is a reactive lesion that originates in the gingiva. Morphological similarity to other epulides and similar nomenclature to neoplastic...
Peripheral ossifying fibroma (POF) is a reactive lesion that originates in the gingiva. Morphological similarity to other epulides and similar nomenclature to neoplastic tumors give rise to obvious problems both at the stage of diagnosis and treatment of POF. Although POF is one of the less common gingival lesions, it accounts for up to 2% of all oral lesions, which means that most general dentists will encounter POF in their practice. This paper aims to present the case of a 56-year-old woman diagnosed with POF. In the described case, POF most likely resulted from chronic periodontal irritation due to the presence of prosthetic crowns. The applied treatment in the form of total excision of POF, removal of irritants and gingivoplasty brought the expected therapeutic effect, i.e. no recurrence in the period of the hitherto follow-up. Terminological difficulties, the basics of differentiating typical gingival tumors, therapeutic options with suggested management of POF, and recurrence rate with the follow-up scheme were discussed. Despite the reactive nature of POF, this lesion recurs up to 20% and can transform to giant POF. For this reason, POF should not be underestimated, and proper diagnosis, treatment, and follow-up are critical to the success of therapy.
Topics: Female; Fibroma, Ossifying; Gingiva; Gingival Neoplasms; Humans; Middle Aged
PubMed: 34528910
DOI: No ID Found