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Orthopedics Jul 1996
Review
Topics: Adolescent; Biopsy, Needle; Bone Neoplasms; Diagnosis, Differential; Female; Hip Joint; Humans; Magnetic Resonance Imaging; Osteoblastoma; Tomography, X-Ray Computed
PubMed: 8823823
DOI: No ID Found -
Oral Oncology Jan 2023Osteoblastoma is a benign tumour with aggressive trait usually seen in young males between 10 and 40 years of age. This condition is quite rare in children. Here, we... (Review)
Review
Osteoblastoma is a benign tumour with aggressive trait usually seen in young males between 10 and 40 years of age. This condition is quite rare in children. Here, we report one such rare osteoblastoma occurring in the maxilla of a 4-year-old boy and discuss the clinical presentation, radiologic and histologic features, and treatment of this patient, and a brief review.
Topics: Male; Child; Humans; Child, Preschool; Osteoblastoma; Maxilla; Diagnosis, Differential; Bone Neoplasms
PubMed: 36481510
DOI: 10.1016/j.oraloncology.2022.106268 -
Skeletal Radiology Oct 2019Osteoblastoma is a rare, benign primary tumor of bone, accounting for < 1% of all bone tumors. We report the case of a 27-year-old female who developed pain and... (Review)
Review
Osteoblastoma is a rare, benign primary tumor of bone, accounting for < 1% of all bone tumors. We report the case of a 27-year-old female who developed pain and swelling five and a half years after a clavicular fracture and was subsequently found to have an osteoblastoma arising at the fracture site. This is the first reported case of an osteoblastoma developing after a fracture, although osteoid osteomas, which are histologically indistinguishable from osteoblastomas, have been reported at prior fracture sites. This report demonstrates that secondary neoplasms such as osteoblastomas should be considered in the differential diagnosis for pain at a healed fracture site recurring years after the initial trauma.
Topics: Adult; Biopsy; Bone Neoplasms; Clavicle; Female; Fractures, Bone; Humans; Magnetic Resonance Imaging; Osteoblastoma; Tomography, X-Ray Computed
PubMed: 30850870
DOI: 10.1007/s00256-019-03197-x -
European Journal of Orthopaedic Surgery... Aug 2017To analyze the clinical and radiographic characteristics, treatment, and outcome of patients with elbow osteoblastoma. (Review)
Review
PURPOSE
To analyze the clinical and radiographic characteristics, treatment, and outcome of patients with elbow osteoblastoma.
PATIENTS AND METHODS
We present 13 patients (7 males and 6 females; mean age, 28 years) diagnosed and treated for an elbow osteoblastoma from 1975 to 2012. Mean follow-up was 29 months (range 12-60 months). Clinical presentation, imaging, surgical treatment, complications, range of elbow motion, and functional outcome were evaluated. The MSTS, DASH, and OXFORD scores were used.
RESULTS
Main symptom was pain (all patients) accompanied by stiffness (8 patients) and swelling or tumefaction (7 patients), with a median duration of symptoms of 32 months (range 6-96 months). Distal humerus was affected in 10 patients, proximal ulna in 2 patients, and proximal radius in one patient. All patients underwent surgical therapy that consisted of curettage of the lesion (7 patients), curettage and bone allografting (3 patients), wide resection (2 patients; total distal humerus and resection of the radial head), and radiofrequency thermal ablation (1 patient). One patient experienced a recurrence after surgical treatment. The mean MSTS score after treatment was 87% (range 50-100%), which corresponds to excellent results.
CONCLUSIONS
Intralesional surgery is successful in tumor control in most patients with osteoblastoma of the elbow. Thermal ablation may be successful for smaller lesions. Most of the patients had a good-to-excellent functional outcome even if they had tumor-related elbow stiffness at diagnosis.
LEVEL OF EVIDENCE
Therapeutic study, Level IV-1.
Topics: Adolescent; Adult; Bone Neoplasms; Child; Elbow; Elbow Joint; Female; Follow-Up Studies; Humans; Humerus; Magnetic Resonance Imaging; Male; Middle Aged; Musculoskeletal Pain; Neoplasm Recurrence, Local; Osteoblastoma; Radius; Range of Motion, Articular; Retrospective Studies; Tomography, X-Ray Computed; Ulna; Young Adult
PubMed: 28634923
DOI: 10.1007/s00590-017-1997-6 -
The Journal of Hand Surgery Apr 2022Osteoblastomas are rare, benign, bone-forming neoplasms that represent less than 1% of all bone tumors and occur mostly in people aged 10 to 30 years. In long bones, the...
Osteoblastomas are rare, benign, bone-forming neoplasms that represent less than 1% of all bone tumors and occur mostly in people aged 10 to 30 years. In long bones, the metadiaphyseal region tends to be most commonly affected. However, to the best of our knowledge, only 11 cases have been reported to occur in the distal radius. We present the clinical, radiological, and histopathological findings of an osteoblastoma of the right distal radius in a 42-year-old woman for whom an open excisional biopsy with nidus removal comprised the treatment and produced a good outcome.
Topics: Adult; Biopsy; Bone Neoplasms; Female; Humans; Osteoblastoma; Radius; Wrist Joint
PubMed: 33840569
DOI: 10.1016/j.jhsa.2021.02.003 -
Archives of Pathology & Laboratory... Oct 2010Osteoblastoma is a rare benign bone tumor. Although the histologic features in most cases are distinctive, there are various permutations that make the diagnosis...
Osteoblastoma is a rare benign bone tumor. Although the histologic features in most cases are distinctive, there are various permutations that make the diagnosis challenging. It can mimic a variety of other benign bone tumors, but more importantly, distinguishing it from osteoblastoma-like osteosarcoma can be difficult. In this case report, I describe the clinicopathologic findings for a 13-year-old adolescent boy with T7 spinal osteoblastoma and review salient clinical, radiographic, and pathologic features of osteoblastoma, as well as the differential diagnoses.
Topics: Adolescent; Bone Neoplasms; Cartilage, Articular; Diagnosis, Differential; Humans; Male; Osteoblastoma; Osteoblasts; Osteoclasts; Spinal Neoplasms; Tomography, X-Ray Computed
PubMed: 20923301
DOI: 10.5858/2010-0201-CR.1 -
Otology & Neurotology : Official... Feb 2022This report describes osteoblastoma of the temporal bone found on a well-child visit. The relevant clinical, radiographic, and histologic features are described. The...
This report describes osteoblastoma of the temporal bone found on a well-child visit. The relevant clinical, radiographic, and histologic features are described. The tumor was completely resected via a transtemporal approach. The differential diagnosis for these tumors include osteoma, giant cell tumor, histiocytosis, aneurysmal bone cyst and sarcoma. Histologic findings are critical for determining the proper diagnosis.
Topics: Bone Cysts, Aneurysmal; Bone Neoplasms; Diagnosis, Differential; Humans; Osteoblastoma; Osteoma, Osteoid; Temporal Bone
PubMed: 35015753
DOI: 10.1097/MAO.0000000000003381 -
Medical Science Monitor : International... Feb 2019BACKGROUND Osteoblastoma is a rare, benign, osteolytic neoplasm commonly found in the spine in early adulthood. Here, we review the clinical characteristics,... (Review)
Review
BACKGROUND Osteoblastoma is a rare, benign, osteolytic neoplasm commonly found in the spine in early adulthood. Here, we review the clinical characteristics, radiographic findings, and surgical management of patients with spinal osteoblastoma. MATERIAL AND METHODS Thirteen patients with osteoblastoma who underwent surgery at our institute from June 2008 to November 2017 were enrolled in this study. The American Spinal Injury Association (ASIA) impairment scale was used to assess neurological function. All patients were treated with either total excision or intralesional piecemeal excision without postoperative radiotherapy. Clinical efficacy was evaluated by visual analog scale (VAS) scores, the Oswestry Disability Index (ODI) of nerve function, physical and radiographic examinations, bone fusion, and neurologic status. RESULTS The follow-up lasted 23-82 months (average, 43.8 months). The average surgical time was 178.1 minutes (range, 100-230 minutes), with an average intraoperative blood loss of 574 mL (range, 230-1100 mL). Postoperatively, VAS scores decreased from 6.2±1.7 to 0.5±0.7 (P<0.001). The preoperative and final ODI scores were 51.1±7.7 and 22.6±4.9, respectively, reflecting a significant decrease (P<0.001). According to the ASIA classification, 3 patients had grade C, 3 patients had grade D, and 7 patients had grade E disease. Three months postoperatively, 1 patient had grade D and 10 patients had grade E disease; ultimately, all cases were grade E disease. Only 1 patient experienced local recurrence and underwent en bloc marginal resection with postoperative radiotherapy. All patients remained neurologically stable without any major complications. CONCLUSIONS Accurate intraoperative localization with complete resection is the key to preventing recurrence. Aggressive surgical resection can achieve satisfactory clinical and radiographic outcomes.
Topics: Adolescent; Adult; Aged; Bone Neoplasms; Child; China; Female; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Osteoblastoma; Plastic Surgery Procedures; Retrospective Studies; Spine; Treatment Outcome
PubMed: 30785872
DOI: 10.12659/MSM.913666 -
Foot (Edinburgh, Scotland) Dec 2020Osteoblastoma is a relatively rare, benign, bone-forming tumor, commonly observed in the second and third decades of life. Spine and the long tubular bones are the most... (Review)
Review
Osteoblastoma is a relatively rare, benign, bone-forming tumor, commonly observed in the second and third decades of life. Spine and the long tubular bones are the most common sites of involvement. Osteoblastoma is infrequently seen in other sites, including the bones of hand and foot. A rare case of a 35-year-old man that presented an osteoblastoma of the cuboid bone is reported. The patient was treated with surgical resection and grafting. After the intervention, the patient recovered with no clinical and radiological evidence of recurrence after one year of follow-up. Several cases of osteoblastoma-like variant of osteosarcoma of the cuboid have been previously reported, but, to our knowledge, this is the first case of conventional and isolated osteoblastoma involving the cuboid bone reported in the literature.
Topics: Adult; Bone Neoplasms; Humans; Male; Osteoblastoma; Tarsal Bones
PubMed: 33039906
DOI: 10.1016/j.foot.2020.101691 -
World Neurosurgery Apr 2020Osteoblastoma is a rare benign aggressive tumor, with one third occurring in the spine. Conversion of osteoblastoma to osteosarcoma is uncommon, and histologically... (Review)
Review
BACKGROUND
Osteoblastoma is a rare benign aggressive tumor, with one third occurring in the spine. Conversion of osteoblastoma to osteosarcoma is uncommon, and histologically proven conversion has been rarely reported.
CASE DESCRIPTION
Cases of 2 patients with rare occurrences of spinal osteoblastomas recurring and transforming into osteosarcomas are presented. Initial presentation, treatment, imaging, and histology findings are described. The outcomes of the patients following surgical intervention for histologically diagnosed osteoblastoma with subsequent transformation to osteosarcoma and relative management are described. A literature review of osteoblastoma converting to osteosarcoma also is provided.
CONCLUSIONS
The rare occurrence of osteoblastoma converting to osteosarcoma imparts several lessons, including performing Enneking appropriate surgery for benign aggressive tumors (Enneking stage 3) and always performing a biopsy, particularly at the time of recurrence if imaging is not pathognomonic for a benign primary spine tumor.
Topics: Adult; Humans; Male; Osteoblastoma; Osteosarcoma; Spinal Neoplasms
PubMed: 31809897
DOI: 10.1016/j.wneu.2019.11.148