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Journal of Comparative Pathology Oct 2019A 7-year-old neutered male domestic shorthair cat was presented with chronic lameness in the right forelimb. A cystic bony lesion was identified in the distal right...
A 7-year-old neutered male domestic shorthair cat was presented with chronic lameness in the right forelimb. A cystic bony lesion was identified in the distal right humerus and amputation was performed. The epiphyseal trabecular bones of the capitulum and trochlea was replaced by a tan to pink, expansile mass that was surrounded by a thin rim of cortical bone. Microscopically, the tumour was composed of a bland, osteoid producing spindle cell population within a well-vascularized fibrous stroma. Radiographical and histological features were consistent with osteoblastoma. Osteoblastoma and the related osteoid osteoma are uncommon, benign osteoblastic tumours that are reported rarely in animals. These tumours should be considered as differential diagnoses for slow growing, cystic bony lesions in cats.
Topics: Animals; Cat Diseases; Cats; Diagnosis, Differential; Humerus; Male; Neoplasms, Bone Tissue; Osteoblastoma
PubMed: 31690411
DOI: 10.1016/j.jcpa.2019.08.007 -
Journal of Clinical Neuroscience :... Mar 2015Benign osteoblastoma is a rare, vascular, osteoid-forming bone tumor that occurs even less frequently in the cranial bones. Benign osteoblastoma of the cranium affects... (Review)
Review
Benign osteoblastoma is a rare, vascular, osteoid-forming bone tumor that occurs even less frequently in the cranial bones. Benign osteoblastoma of the cranium affects women slightly more often than men and typically presents in the first three decades of life. Although clinical presentation can vary depending on location, cranial osteoblastoma usually presents as a painful, non-mobile, subcutaneous mass or swelling. On CT scan, it generally presents as a well-demarcated, mixed lytic and sclerotic lesion, with enlarged diploe, thinning outer and/or inner tables, and varying degrees of calcification. It is hypo to isointense on T1-weighted MRI and has variable presentation on T2-weighted MRI. Gross total resection is the definitive treatment, while subtotal resection is utilized when it is necessary to preserve critical adjacent neurovascular structures.
Topics: Bone Cysts, Aneurysmal; Bone Neoplasms; Diagnosis, Differential; Female; Fibrous Dysplasia of Bone; Giant Cell Tumor of Bone; Humans; Magnetic Resonance Imaging; Male; Meningeal Neoplasms; Meningioma; Osteoblastoma; Osteoma, Osteoid; Osteosarcoma; Skull; Tomography, X-Ray Computed
PubMed: 25595957
DOI: 10.1016/j.jocn.2014.10.002 -
Skeletal Radiology Nov 2000We report an osteoblastoma-like osteosarcoma in the right proximal fibula in a 22-year-old woman. Radiographs showed an irregular osteolytic lesion from the metaphysis...
We report an osteoblastoma-like osteosarcoma in the right proximal fibula in a 22-year-old woman. Radiographs showed an irregular osteolytic lesion from the metaphysis to the epiphysis in the proximal fibula with partial destruction of cortical bone. Tissue from a biopsy indicated a typical osteoblastoma. Curettage and bone graft was performed. One year after the surgery, local recurrence occurred, and a wide excision was performed. Histological examination of the en-bloc surgical specimen revealed the tumor had permeated through the host bony trabeculae, although the nuclear atypia was not marked. Immunohistochemical expression of MIB-1 was detected in 9.0% of cells.
Topics: Adult; Antigens, Nuclear; Biopsy; Bone Neoplasms; Female; Fibula; Humans; Ki-67 Antigen; Magnetic Resonance Imaging; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Nuclear Proteins; Osteoblastoma; Osteosarcoma
PubMed: 11201036
DOI: 10.1007/s002560000271 -
World Neurosurgery Jun 2020Osteoblastomas are rare primary bone tumors with a predilection for the spine. The extraosseous growth pattern is rare, and to our knowledge, only 2 cases of fully... (Review)
Review
BACKGROUND
Osteoblastomas are rare primary bone tumors with a predilection for the spine. The extraosseous growth pattern is rare, and to our knowledge, only 2 cases of fully extraosseous osteoblastomas have been previously reported.
CASE DESCRIPTION
A man aged 36 years presented with a 7-month history of low back pain radiating to the gluteal area. On examination, a typical L5 radiculopathy was noted. The radiologic examinations conducted in the previous months pointed out the rapid growth of an extraosseous mass occluding the right L5-S1 foramen. Partial laminectomy was performed to achieve gross total resection. Histological analysis was consistent with osteoblastoma.
CONCLUSIONS
Osteoblastomas with extraosseous extension are uncommon, and an exclusively extraosseous presentation is anecdotal. This can lead to preoperative misdiagnosis when typical radiologic characteristics of bone-forming tumors are missing. We describe the case of an extraosseous lumbar osteoblastoma whose clinical and radiologic presentation was suggestive of malignancy.
Topics: Adult; Humans; Laminectomy; Lumbosacral Region; Male; Osteoblastoma; Spinal Neoplasms
PubMed: 32217174
DOI: 10.1016/j.wneu.2020.03.081 -
Head and Neck Pathology Dec 2012
Topics: Bone Neoplasms; Humans; Male; Maxillary Sinus Neoplasms; Osteoblastoma; Young Adult
PubMed: 22528828
DOI: 10.1007/s12105-012-0356-5 -
Skeletal Radiology Oct 2000Osteoblastoma is a benign bone tumor with uncertain radiologic and typical histologic pattern that, in most cases, can be diagnosed without any problems. Usually, it is... (Review)
Review
Osteoblastoma is a benign bone tumor with uncertain radiologic and typical histologic pattern that, in most cases, can be diagnosed without any problems. Usually, it is a solitary bone tumor. The case presented is a 9-year-old child with multiple osteoblastomas occurring in multiple bones of the right hand. The child had pain in his right hand for several weeks. On physical examination, no swelling or other symptoms were elicited. All lesions noted radiologically were treated by curettage, and in all the pattern of osteoblastoma was diagnosed.
Topics: Bone Neoplasms; Child; Curettage; Hand; Humans; Male; Osteoblastoma; Radiography
PubMed: 11127685
DOI: 10.1007/s002560000257 -
Oral Surgery, Oral Medicine, Oral... Jul 2019Epithelioid osteoblastoma is a clinically aggressive subtype of osteoblastoma that favors the mandible and the maxilla. Its histologic features lie on a spectrum between... (Review)
Review
Epithelioid osteoblastoma is a clinically aggressive subtype of osteoblastoma that favors the mandible and the maxilla. Its histologic features lie on a spectrum between conventional osteoblastoma and low-grade osteosarcoma, thus making it difficult at times to confirm the diagnosis. It is known to have a high risk of recurrence after surgical resection, but it is a benign entity and does not have the propensity to metastasize. To our knowledge, there are no published reports on findings of epithelioid osteoblastoma on positron emission tomography/computed tomography (PET/CT). We report a case of a 25-year-old male patient with a diagnosis of epithelioid osteoblastoma of the mandible. The lesion exhibited significantly increased fluorodeoxyglucose uptake on PET/CT with a maximum standardized uptake value of 5.5. PET/CT is not specific in differentiating between malignant and benign bone lesions but may be necessary to rule out distant lesions when a confirmed diagnosis of epithelioid osteoblastoma cannot be obtained through histologic examination.
Topics: Adult; Diagnosis, Differential; Fluorodeoxyglucose F18; Humans; Male; Mandible; Mandibular Neoplasms; Neoplasm Recurrence, Local; Osteoblastoma; Positron Emission Tomography Computed Tomography
PubMed: 30704897
DOI: 10.1016/j.oooo.2018.12.021 -
Orthopaedics & Traumatology, Surgery &... Oct 2010We report the case of an osteoblastoma of the hamate bone that was successfully treated by curettage. This tumor is very rare in a carpal bone and only nine cases have...
We report the case of an osteoblastoma of the hamate bone that was successfully treated by curettage. This tumor is very rare in a carpal bone and only nine cases have been reported in the literature. Pathological examination is mandatory before treatment due to the lack of distinctive clinical and radiological features. Osteoblastomas are benign, but potentially aggressive bone tumors. Treatment of the lesion may either be a conservative "intralesional resection" or radical "wide en bloc resection". The latter option, which has non-negligible functional consequences in the wrist, should be reserved for recurrence after curettage but may also be considered a primary immediate alternative for aggressive forms.
Topics: Adult; Biopsy; Bone Cysts; Bone Neoplasms; Curettage; Delayed Diagnosis; Hamate Bone; Humans; Magnetic Resonance Imaging; Male; Osteoblastoma; Osteolysis; Radiography
PubMed: 20692218
DOI: 10.1016/j.otsr.2010.02.014 -
Dento Maxillo Facial Radiology Jan 2005Benign osteoblastoma is a bone tumour that seldom occurs in the facial bones. The objective of this article is to add one more case of this rare lesion to the academic... (Review)
Review
Benign osteoblastoma is a bone tumour that seldom occurs in the facial bones. The objective of this article is to add one more case of this rare lesion to the academic literature and to provide a systematic review of previously published cases. A new case of benign osteoblastoma is presented and clinical, radiographic and microscopic aspects, as well as differential diagnosis, treatment and follow-up are discussed. The importance of the correct diagnosis of this type of lesion is stressed, since it presents a clinical, radiographic and microscopic similarity to other bone lesions, including malignant tumours, which may lead the professional into conducting the case in an improper manner.
Topics: Child; Diagnosis, Differential; Humans; Male; Mandibular Neoplasms; Osteoblastoma; Radiography
PubMed: 15709098
DOI: 10.1259/dmfr/24385194 -
World Journal of Surgical Oncology Mar 2012Osteoblastoma is a rare bone tumor which is mostly found in the vertebral column and long bone. We describe a 59-year-old woman with osteoblastoma in the right fifth... (Review)
Review
Osteoblastoma is a rare bone tumor which is mostly found in the vertebral column and long bone. We describe a 59-year-old woman with osteoblastoma in the right fifth posterior segment of the rib, whose presenting symptoms were right back pain for two years and awakened at night. Chest computer tomography (CT) and thoracic spine magnetic resonance (MR) imaging findings included an expansile lesion of the right fifth rib and an ossified matrix. Surgical resection of the lesion confirmed a benign osteoblastoma. 12 months follow-up revealed disappearance of right back pain. Rib osteoblastoma in plain film has been described previously; however, to our knowledge this is the only case report emphasized in CT and MR imaging.
Topics: Bone Neoplasms; Female; Humans; Magnetic Resonance Imaging; Middle Aged; Osteoblastoma; Ribs; Tomography, X-Ray Computed
PubMed: 22397553
DOI: 10.1186/1477-7819-10-49