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Clinical Radiology Jan 2004
Topics: Adolescent; Bone Neoplasms; Diagnosis, Differential; Femur; Humans; Magnetic Resonance Imaging; Male; Osteoblastoma; Osteosarcoma
PubMed: 14697384
DOI: 10.1016/j.crad.2003.08.010 -
The Pan African Medical Journal 2021
Topics: Aged; Bone Neoplasms; Humans; Osteoblastoma; Osteoma, Osteoid; Parietal Bone; Skull
PubMed: 34539955
DOI: 10.11604/pamj.2021.39.158.29766 -
The Journal of Hand Surgery Nov 2019Osteoblastoma is a benign aggressive primary bone tumor that occasionally presents in the hand. Because surgical treatment remains the mainstay of treatment, there are...
Osteoblastoma is a benign aggressive primary bone tumor that occasionally presents in the hand. Because surgical treatment remains the mainstay of treatment, there are no established nonsurgical pharmacological options for patients in whom resection is not feasible. Novel therapies, such as denosumab, are currently being investigated in primary bone tumors. We report a case of osteoblastoma of the first metacarpal that was successfully treated with denosumab. The patient showed a rapid and dramatic response to treatment that led to the transformation of a locally destructive tumor into an ossified painless mass, restoring function while avoiding surgery.
Topics: Adolescent; Biopsy, Needle; Bone Neoplasms; Denosumab; Follow-Up Studies; Humans; Immunohistochemistry; Injections, Subcutaneous; Magnetic Resonance Imaging; Male; Metacarpal Bones; Music; Osteoblastoma; Risk Assessment; Thumb; Tomography, X-Ray Computed; Treatment Outcome
PubMed: 30910238
DOI: 10.1016/j.jhsa.2019.02.001 -
Balkan Medical Journal Jan 2023
Topics: Humans; Osteoblastoma; Tibia; Fibroma; Diagnosis, Differential
PubMed: 36482109
DOI: 10.4274/balkanmedj.galenos.2022.2022-10-34 -
Journal of Neurosurgery Oct 1997The benign osteoblastoma is rarely seen as a tumor of the facial bone in infancy or early childhood. Only five cases with nasal involvement have been reported in the... (Review)
Review
The benign osteoblastoma is rarely seen as a tumor of the facial bone in infancy or early childhood. Only five cases with nasal involvement have been reported in the literature. The authors present a case of osteoblastoma of the nasal cavity, the nasal bone, the ethmoid sinus, and the anterior cranial base. This 3-year-old girl presented with a tumor surrounding the left medial canthus. Imaging studies, including x-ray films, computerized tomography scans, magnetic resonance images, a (99m)Tc-scintigram, and angiograms, confirmed the location of the tumor. A biopsy specimen of tumor was obtained intranasally and the pathological diagnosis was an osteoblastic tumor suggestive of osteoblastoma. Although the tumor margin was well defined on the radiological images, it was difficult to determine the exact margin during the operation. Therefore, it is important to show how to excise the tumor completely under direct view. With the use of a "dismasking flap," it was possible to resect the benign osteoblastoma completely from the nasal cavity, even though it extended into the orbit, the maxilla, and the anterior cranial base.
Topics: Angiography; Biopsy; Child, Preschool; Ethmoid Sinus; Female; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Maxillary Neoplasms; Nasal Bone; Nasal Cavity; Neoplasm Invasiveness; Nose Neoplasms; Orbital Neoplasms; Osteoblastoma; Paranasal Sinus Neoplasms; Radiopharmaceuticals; Skull Base; Skull Neoplasms; Technetium; Tomography, X-Ray Computed
PubMed: 9322852
DOI: 10.3171/jns.1997.87.4.0625 -
World Neurosurgery Mar 2019Epithelioid osteoblastoma of the cranium is extremely rare and can mimic other etiologies on radiographic imaging, pathology, and symptomatology.
BACKGROUND
Epithelioid osteoblastoma of the cranium is extremely rare and can mimic other etiologies on radiographic imaging, pathology, and symptomatology.
CASE DESCRIPTION
An 18-year-old male patient had a 3-week history of a palpable left temporal mass. Magnetic resonance imaging revealed a large, extra-axial, hypervascular mass in the left temporal bone, with bony erosion and intracranial extension. The patient underwent surgical near gross-total resection of the mass. Initial frozen microscopic examination of the tumor was inconclusive. The postoperative course was uneventful, and the patient was discharged a few days later. Final pathology confirmed the diagnosis of epithelioid osteoblastoma.
CONCLUSIONS
Epithelioid osteoblastoma of the skull base is exceedingly rare but should be included in the differential diagnoses of all extra axial tumors. Preoperative radiographic clues are limited, and final diagnosis relies solely on accurate pathologic examination. A diagnosis of epithelioid osteoblastoma should be considered for all cranial bone-based tumors, as an incorrect diagnosis of another radiographic and histologic mimic could lead to the patient receiving unnecessary and harmful neoadjuvant/adjuvant chemotherapy or radiotherapy.
Topics: Adolescent; Cerebral Angiography; Humans; Magnetic Resonance Imaging; Male; Osteoblastoma; Skull Base Neoplasms; Temporal Bone
PubMed: 30521959
DOI: 10.1016/j.wneu.2018.11.209 -
Journal of the California Dental... Dec 2016This case study involves a 22-year-old male who experienced moderate pain in the left side of the mandible for two months. He was diagnosed with an osteoblastoma and...
This case study involves a 22-year-old male who experienced moderate pain in the left side of the mandible for two months. He was diagnosed with an osteoblastoma and treated with local excision, curettage and extraction of the involved teeth. Radiographic follow-up indicated that the site healed well. Clinical, radiographic and histopathologic features are discussed. Osteoblastoma requires interdisciplinary care and should be considered in the differential diagnosis of mixed-density lesions detected in the jaws.
Topics: Diagnosis, Differential; Humans; Male; Mandibular Neoplasms; Osteoblastoma; Radiography, Panoramic; Tomography, X-Ray Computed; Young Adult
PubMed: 29045089
DOI: No ID Found -
The Journal of Laryngology and Otology Sep 1997The presence of a benign osteoblastoma in the ethmoid sinus is rare and only a few cases have been reported. This is a case of a benign osteoblastoma arising from the... (Review)
Review
The presence of a benign osteoblastoma in the ethmoid sinus is rare and only a few cases have been reported. This is a case of a benign osteoblastoma arising from the perpendicular plate of the ethmoid bone with extension to the nasal cavity. The diagnosis and management of this unusual lesion, as well as the histopathology and the imaging characteristics are reviewed. We also review the previously reported cases of benign osteoblastomas of different origin, with nasal cavity involvement.
Topics: Adult; Ethmoid Bone; Female; Humans; Nasal Cavity; Nose Neoplasms; Osteoblastoma; Skull Neoplasms; Tomography, X-Ray Computed
PubMed: 9373556
DOI: 10.1017/s0022215100138836 -
Bulletin of the NYU Hospital For Joint... 2010Osteoblastoma is an extremely rare entity that represents less than 1% of all bone tumors, and affects twice as many males as females with peak incidence between 15 and... (Review)
Review
Osteoblastoma is an extremely rare entity that represents less than 1% of all bone tumors, and affects twice as many males as females with peak incidence between 15 and 20 years. Osteoblastomas commonly affect axial bones, long bones, bones of the foot and hand, and less commonly the pelvis, scapula, ribs, and clavicle. Osteoblastoma does not have a classic presentation, but can vary with the location and size of the tumor. The main complaint is often progressive pain localized at the tumor site. Osteoblastoma is a benign tumor with an aggressive behavior. The treatment is wide surgical resection, otherwise it continues to enlarge and destroy the bone and surrounding structures. We report a 32-year-old male with an osteoblastoma of this sternum who was treated with an en-bloc resection and reconstruction with Marlex((R)) and a methylmethacrylate plate.
Topics: Adult; Biopsy; Bone Neoplasms; Bone Plates; Humans; Magnetic Resonance Imaging; Male; Methylmethacrylate; Orthopedic Procedures; Osteoblastoma; Polypropylenes; Prosthesis Design; Sternum; Surgical Mesh; Tomography, X-Ray Computed; Treatment Outcome
PubMed: 20345366
DOI: No ID Found -
American Journal of Rhinology & Allergy Mar 2018With the exception of osteomas, bone neoplasms that originate in the sinonasal cavity are seldom diagnosed on preoperative imaging due to a lack of characteristic... (Review)
Review
BACKGROUND
With the exception of osteomas, bone neoplasms that originate in the sinonasal cavity are seldom diagnosed on preoperative imaging due to a lack of characteristic radiographic features. Here we described the unusual occurrence of an osteoblastoma in the paranasal sinuses, and we drew focus to its salient imaging features. A highly unique imaging sign was indicated, and its pathologic basis was explained, with concurrent review of the literature.
METHODS
Case series and review of the literature.
RESULTS
Two cases of sinonasal osteoblastoma were managed by definitive surgical resection. Both tumors on preoperative computed tomography demonstrated an expansile, heterogeneous fibro-osseous lesion with an eccentric, mature osseous cap. The dense osseous cap seen on imaging corresponded to a rim of mature bone on histopathology. A review of existing literature revealed the presence of this imaging sign in all reported cases.
CONCLUSION
Sinonasal osteoblastoma is an extremely rare entity with undefined imaging characteristics to guide preoperative decision-making. Here we reported, to our knowledge, the first description of a characteristic imaging sign of an eccentric, mature osseous cap, which corresponded histologically to a single peripheral layer rim of osteoblasts, a unique trait of osteoblastoma.
Topics: Adolescent; Diagnosis, Differential; Endoscopy; Female; Fibroma, Ossifying; Humans; Male; Osteoblastoma; Osteoma; Paranasal Sinus Neoplasms; Paranasal Sinuses; Preoperative Period; Tomography, X-Ray Computed; Treatment Outcome; Young Adult
PubMed: 29644901
DOI: 10.1177/1945892418762658