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Cutis Dec 1985Primary osteoma cutis in a 24-year-old white woman presented as a small hard tumor beneath the skin of the left breast. Histologic examination of the lesion showed...
Primary osteoma cutis in a 24-year-old white woman presented as a small hard tumor beneath the skin of the left breast. Histologic examination of the lesion showed typical osteoma cutis. This was likely to be a case of primary osteoma cutis since the history and results of physical examination and laboratory tests failed to reveal other abnormalities.
Topics: Adult; Breast; Female; Humans; Osteoma; Skin Neoplasms
PubMed: 4075842
DOI: No ID Found -
The British Journal of Dermatology Jun 2002Osteoma cutis, also called cutaneous ossification, refers to the rare occurrence of bone in the skin. It may be primary, occurring in normal skin, or secondary,... (Review)
Review
Osteoma cutis, also called cutaneous ossification, refers to the rare occurrence of bone in the skin. It may be primary, occurring in normal skin, or secondary, occurring in disrupted skin tissue. A 42-year-old white woman presented with long-standing progressive primary osteoma cutis involving her head and neck, trunk and extremities. She had craniofacial dysmorphism with mid-face hypoplasia, including saddle nose deformity, mild to moderate generalized joint hypermobility, extensive paravertebral ossification, and disc space calcification. The differential diagnosis for this entity is presented. This phenotype may be a previously undescribed syndrome.
Topics: Craniofacial Dysostosis; Female; Humans; Middle Aged; Ossification, Heterotopic; Recurrence; Skin Diseases; Syndrome
PubMed: 12072082
DOI: 10.1046/j.1365-2133.2002.04674.x -
Anais Brasileiros de Dermatologia 2017Osteoma cutis or cutaneous ossification is a rare entity characterized by the formation of bone in the skin. We present an isolated primary osteoma cutis located on the...
Osteoma cutis or cutaneous ossification is a rare entity characterized by the formation of bone in the skin. We present an isolated primary osteoma cutis located on the palm, an atypical location.
Topics: Adult; Biopsy; Bone Diseases, Metabolic; Hand Dermatoses; Humans; Male; Ossification, Heterotopic; Pain; Rare Diseases; Skin Diseases, Genetic
PubMed: 29267465
DOI: 10.1590/abd1806-4841.20175464 -
A.M.A. Archives of Dermatology and... May 1951
Topics: Acne Vulgaris; Bone Diseases, Metabolic; Cicatrix; Humans; Ossification, Heterotopic; Osteoma; Skin; Skin Diseases, Genetic; Trichloroacetic Acid
PubMed: 14818436
DOI: No ID Found -
Acta Dermato-venereologica Nov 2019
Topics: Alopecia; Bone Diseases, Metabolic; Clobetasol; Female; Glucocorticoids; Humans; Hydroxychloroquine; Lichen Planus; Middle Aged; Ossification, Heterotopic; Scalp; Scalp Dermatoses; Skin Diseases, Genetic; Treatment Outcome
PubMed: 31449318
DOI: 10.2340/00015555-3295 -
Dermatology Online Journal Jan 2016Osteoma cutis is a rare soft tissue ossification of cutaneous tissue and may be primary or secondary. In the majorityof cases it is clinically asymptomatic and may...
BACKGROUND
Osteoma cutis is a rare soft tissue ossification of cutaneous tissue and may be primary or secondary. In the majorityof cases it is clinically asymptomatic and may detected incidentally on radiographic examination. Cone beam computed tomography (CBCT) has can be of great assistance in the detection of this asymptomatic lesion.
OBJECTIVES
In this retrospective study, the prevalence and different radiographic appearance of osteoma cutis was evaluated.
MATERIALS AND METHODS
A total of 6,500 CBCT images were evaluated for the presence of osteoma cutis. Ectopic existence of calcified tissue within the soft tissue of the dermis or epidermis that was incompatible with the calcification of other anatomic structures or soft tissue calcifications was considered to be osteoma cutis. Accordingly, the detected patterns were divided into four distinct groups: (1) a single nodule, (2) plate-like lesion, (3) single or multiple depth lesion(s), trans-epidermal, and (4) multiple, disseminated lesions of various sizes known as multiple miliary. The data were evaluated in terms of prevalence and variations. The frequency, total prevalence, percentage and the prevalence of different radiographic forms of this lesion were calculated.
RESULTS
One hundred and forty eight (2.27%) cases of 6,500 evaluated tomograms had osteoma cutis. Of these, 5 (0.07%) were in the form of a single nodule, 4 (0.06%) were single, plate-like lesions, 7 (0.1%) were multiple plate-like lesions, 2 (0.03%) were in the form of a deep thread-like lesion, and 130 (2%) presented as multiple disseminated lesions.
CONCLUSION
According to the radiographic views, osteoma cutis may be categorized into single nodular, single or multiple plate- like, deep, and multiple disseminated forms. Of the mentioned radiogarphic patterns, the multiple disseminated form (miliary) hada higher prevalence in our study. CBCT images enable accurate evaluation of the nature and frequency of osteoma cutis.
Topics: Adult; Aged; Bone Neoplasms; Cone-Beam Computed Tomography; Facial Neoplasms; Female; Humans; Imaging, Three-Dimensional; Male; Middle Aged; Ossification, Heterotopic; Osteoma; Skin; Skin Neoplasms
PubMed: 26990467
DOI: No ID Found -
Journal of the American Academy of... Aug 2000Pseudoxanthoma elasticum (PXE) is a heritable disorder of elastic fibers characterized by yellowish, coalescing papules on the loose and wrinkled flexural area. There...
Pseudoxanthoma elasticum (PXE) is a heritable disorder of elastic fibers characterized by yellowish, coalescing papules on the loose and wrinkled flexural area. There have been no reports of osteoma cutis associated with PXE. A 17-year-old Korean girl presented cutis laxa-like marked wrinkling on the flexural area, and a skin biopsy specimen revealed multiple foci of ossification with irregularly clumped, basophilic-stained elastic fibers in the reticular dermis and calcium deposits along the elastic fibers. Ultrasonographic evaluation showed multiple tiny osteomas diffusely scattered along the entire abdominal wall, axillae, and medial aspect of the upper arms. We report the first case of osteoma cutis coexisting with cutis laxa-like PXE.
Topics: Adolescent; Biopsy; Cutis Laxa; Diagnosis, Differential; Female; Humans; Osteoma; Pseudoxanthoma Elasticum; Skin; Skin Neoplasms
PubMed: 10901716
DOI: 10.1067/mjd.2000.103188 -
Journal of the European Academy of... Jan 2018
Topics: Bone Diseases, Metabolic; Facial Dermatoses; Female; Humans; Middle Aged; Ossification, Heterotopic; Skin Diseases, Genetic
PubMed: 28662301
DOI: 10.1111/jdv.14444 -
Journal of Dermatological Case Reports Dec 2011Miliary osteoma cutis (OC) of the face is a rare benign extra skeletal bone formation. For our knowledge, only 23 cases have been reported in the English literature....
BACKGROUND
Miliary osteoma cutis (OC) of the face is a rare benign extra skeletal bone formation. For our knowledge, only 23 cases have been reported in the English literature. These lesions may be primary or secondary. They cause diagnostic, therapeutic and cosmetic concern especially in women who are usually concerned. Our purpose is to present a case which is completely documented with the clinical, histological and radiological findings. We also report a possible pathogenic theory according to our histologic findings.
MAIN OBSERVATION
We report a case of a multiple miliary OC of the face in a 45-year-old woman which suffered from gravidarum acne. These lesions were treated by focal surgical treatment.
CONCLUSIONS
Based on our histological findings, an osteoblastic metaplasia seems to be a possible pathogenic theory. This metaplasia seems to be secondary to a chronic inflammation. Concerning therapeutic procedures, they are non consensual and debated and are based on surgical or medical treatment. More reports are needed in order to assess the therapeutic management of this disease and its inducing factors.
PubMed: 22408708
DOI: 10.3315/jdcr.2011.1082 -
Der Hautarzt; Zeitschrift Fur... Feb 2022There are many different types of skin neoplasms in children and most are benign. Dermatologists should be able to differentiate between the various types of benign skin... (Review)
Review
There are many different types of skin neoplasms in children and most are benign. Dermatologists should be able to differentiate between the various types of benign skin neoplasms and be able to recommend optimal treatment to concerned patients. Surgical removal of benign skin neoplasms is often the only treatment option. The aim of this paper is to provide a general overview of epidermal lesions (e.g., inflammatory linear verrucous epidermal nevus [ILVEN], nevus sebaceous), tumors of the epidermal appendages (e.g. pilomatrixoma), cutaneous neoplasms (e.g. angiofibroma), fibromatoses (e.g., knuckle pads), tumors comprised of fat, muscle, or bone tissue (e.g., osteoma cutis, subungual exostosis), epidermal cysts and pseudocysts, and pathologic fibrosis reactions after dermal injury (keloid). Scientific data are scarce and only in the last decade has it been possible to perform histopathological examinations and genetic studies together with detailed phenotyping to gain new understanding of the pathogenetic mechanisms.
Topics: Child; Epidermal Cyst; Hair Diseases; Humans; Nevus; Nevus, Pigmented; Skin Neoplasms
PubMed: 35029698
DOI: 10.1007/s00105-021-04935-w