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Surgical Oncology Clinics of North... Oct 2011Infiltration by lung tumor of adjacent anatomic structures including major vessels, main bronchi, and chest wall not only influences the oncologic severity of the... (Review)
Review
Infiltration by lung tumor of adjacent anatomic structures including major vessels, main bronchi, and chest wall not only influences the oncologic severity of the disease but also increases the technical complexity of surgery, requiring extended resections and demanding reconstructive procedures. Completeness of resection represents in every case one of the main factors influencing the long-term outcome of patients. Technical and oncologic aspects of extended operations, including resection of Pancoast tumors and chest wall, bronchovascular sleeve resections, and en bloc resections of major thoracic vessels, are reported in this article.
Topics: Bronchi; Humans; Lung Neoplasms; Pancoast Syndrome; Thoracic Wall; Vascular Neoplasms
PubMed: 21986269
DOI: 10.1016/j.soc.2011.07.007 -
Revista de La Facultad de Ciencias... 2014We described a patient who was diagnosed with a Pancoast tumor in the Neumológico Benéfico Jurídico Hospital. This neoplastic non metastatic disease more frequently...
We described a patient who was diagnosed with a Pancoast tumor in the Neumológico Benéfico Jurídico Hospital. This neoplastic non metastatic disease more frequently affects the brachial plexus. Therefore, a differential diagnosis of the painful shoulder was carried out and the patient was admitted in our center with the probable Pancoast tumor diagnosis. Subsequently, its study continued and the clinical suspicion was confirmed by a computerized tomography and a magnetic resonance, to be also confirmed later on with an anatomopathological study.
Topics: Aged; Brachial Plexus; Carcinoma, Small Cell; Humans; Male; Pancoast Syndrome
PubMed: 25036449
DOI: No ID Found -
The British Journal of Clinical Practice 1993
Topics: Electromyography; Female; Humans; Middle Aged; Neural Conduction; Pancoast Syndrome; Spinal Cord Diseases
PubMed: 8260350
DOI: No ID Found -
The Annals of Thoracic Surgery Sep 2018Several different surgical approaches to anterior Pancoast tumors have been proposed. The osteomuscular-sparing transmanubrial approach allows optimal exposure and...
Several different surgical approaches to anterior Pancoast tumors have been proposed. The osteomuscular-sparing transmanubrial approach allows optimal exposure and control of apical chest wall structures, but it requires an additional thoracotomy to perform the lobectomy with radical lymph node resection. The presented technique combines the osteomuscular-sparing transmanubrial approach with robotic-assisted upper lobectomy in a severely obese patient, thereby reducing the invasiveness of the surgical approach and the postoperative complications.
Topics: Obesity, Morbid; Pancoast Syndrome; Robotic Surgical Procedures; Robotics; Thoracotomy
PubMed: 29654726
DOI: 10.1016/j.athoracsur.2018.03.013 -
The Annals of Thoracic Surgery Dec 1998
Topics: Case-Control Studies; Combined Modality Therapy; Humans; Pancoast Syndrome; Survival Analysis
PubMed: 9930529
DOI: 10.1016/s0003-4975(98)01238-7 -
Seminars in Roentgenology Oct 1977
Topics: Adult; Humans; Lung; Lung Diseases; Middle Aged; Pancoast Syndrome; Pleura; Pleural Diseases; Radiography
PubMed: 929216
DOI: 10.1016/0037-198x(77)90043-8 -
The Annals of Thoracic Surgery Jul 1998The evolution of therapy in 105 patients with superior sulcus (Pancoast) tumor over the past 42 years was reviewed.
BACKGROUND
The evolution of therapy in 105 patients with superior sulcus (Pancoast) tumor over the past 42 years was reviewed.
METHODS
There were 82 men and 23 women aged 30 to 75 years. Tumor cell types were: squamous, 41 (39%); adenocarcinoma, 23 (21.9%); anaplastic, 14 (13.3%); undetermined, 12 (11.4%); mixed, 9 (8.7%); and large cell 6 (5.7%). Therapy was based on extent of disease and lymph node involvement. There were 5 treatment groups: I, preoperative radiation and operation (n = 28); II, operation and postoperative radiation (n = 16); III, radiation (n = 37); IV, preoperative chemotherapy, radiation, and operation (n = 11); and V, operation (n = 12).
RESULTS
The median survival for group I was 21.6 months; group II, 6.9 months; group III, 6 months; and group V, 36.7 months. Median survival for group IV has not yet been reached (estimated at 72% at 5 years). On univariate analysis, mediastinal lymph node involvement, Horner syndrome, TNM classification, and method of therapy affected survival. On multivariate regression analysis, only N2 and N3 disease and method of therapy were significant (p < 0.05).
CONCLUSIONS
The optimal treatment for superior sulcus tumor was preoperative radiation and operation. However, triple modality therapy, although promising, requires longer follow-up.
Topics: Adenocarcinoma; Adult; Aged; Analysis of Variance; Anaplasia; Carcinoma, Large Cell; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Female; Follow-Up Studies; Horner Syndrome; Humans; Lymphatic Metastasis; Male; Mediastinum; Middle Aged; Multivariate Analysis; Neoplasm Staging; Pancoast Syndrome; Pneumonectomy; Radiotherapy, Adjuvant; Regression Analysis; Retrospective Studies; Survival Rate
PubMed: 9692463
DOI: 10.1016/s0003-4975(98)00374-9 -
Interactive Cardiovascular and Thoracic... Nov 2016A best evidence topic in cardiothoracic surgery was written according to a structured protocol. The question addressed was whether induction (neoadjuvant)... (Review)
Review
A best evidence topic in cardiothoracic surgery was written according to a structured protocol. The question addressed was whether induction (neoadjuvant) chemoradiotherapy (iCRT) compared with other therapeutic strategies improves survival in patients with Pancoast tumours. Altogether 248 papers were identified using the below-mentioned search. Ten of them represented the best evidence to answer the clinical question. The author, journal, date and country of publication, patient group, relevant outcomes and weaknesses were tabulated. Four studies were retrospective comparative studies of induction chemoradiotherapy and surgery (trimodal therapy) versus other therapeutic strategies. Two studies were retrospective and four were prospective investigating trimodal therapy. These papers comprised a total of 550 patients. The overall survival was better with trimodal therapy compared with RT (radiotherapy) followed by surgery group in all three comparative studies. The 2-year survival varied in the trimodal therapy group from 70 to 93%, in comparison to RT group where variation was from 22 to 49%. Five-year survival for trimodal therapy varied between 36.4 and 84% in the results of two comparative studies, compared with 11 and 49% for RT and surgery, respectively. One paper looked at survival in patients who underwent surgery alone [30% at 2-year and 20% at 4-year overall survival (OS)]. The 5-year OS in the retrospective group varied between 38 and 59%. Similar results were reported for the prospective group with 5-year OS between 44 and 56%. Despite a large variation in pCR (complete pathological response) (15-93%) and R0 (77-100%) reported, both represented a positive prognostic factor for survival. Three papers looked at the impact of staging following induction chemoradiotherapy. The majority of patients had T3 disease. An advantage in survival was seen in patients with early disease compared with advanced stage. No randomized controlled trials were identified. All the 10 articles suggested there was a benefit in trimodal therapy with improvement in overall survival. We conclude that combining induction chemoradiotherapy with surgery for Pancoast tumour may offer a survival benefit compared with radiotherapy with surgery or surgery alone.
Topics: Aged; Antineoplastic Agents; Humans; Induction Chemotherapy; Male; Pancoast Syndrome; Prognosis; Survival Rate; United Kingdom
PubMed: 27365009
DOI: 10.1093/icvts/ivw216 -
Journal of the Indian Medical... Jun 1984
Topics: Adenocarcinoma; Female; Humans; Lymphatic Metastasis; Pancoast Syndrome
PubMed: 6491320
DOI: No ID Found -
The Journal of the Association of... Oct 1980
Topics: Adult; Humans; Male; Middle Aged; Pancoast Syndrome; Radiography
PubMed: 7228837
DOI: No ID Found