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Interactive Cardiovascular and Thoracic... Jun 2009A case of tension pneumocephalus following Pancoast tumor resection is presented. Conservative management was successful. The presenting symptoms and signs, diagnostic...
A case of tension pneumocephalus following Pancoast tumor resection is presented. Conservative management was successful. The presenting symptoms and signs, diagnostic methods and options for treatment are discussed and reviewed.
Topics: Carcinoma, Squamous Cell; Chest Tubes; Humans; Male; Middle Aged; Neoadjuvant Therapy; Pancoast Syndrome; Pneumocephalus; Pneumonectomy; Posture; Radiotherapy, Adjuvant; Suction; Thoracotomy; Tomography, X-Ray Computed; Treatment Outcome
PubMed: 19254944
DOI: 10.1510/icvts.2008.198028 -
Current Problems in Cancer 2003
Review
Topics: Algorithms; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Combined Modality Therapy; Diagnostic Imaging; Humans; Lung Neoplasms; Pancoast Syndrome; Postoperative Complications; Prognosis; Radiotherapy; Survival Rate
PubMed: 12717414
DOI: 10.1016/s0147-0272(03)00018-7 -
JNMA; Journal of the Nepal Medical... Feb 2022Small cell lung cancer mostly arises centrally in the large bronchi. The literature search revealed very limited cases of small cell lung cancer arising at the upper...
Small cell lung cancer mostly arises centrally in the large bronchi. The literature search revealed very limited cases of small cell lung cancer arising at the upper part of the pulmonary sulcus near the thoracic inlet as superior sulcus tumor and also manifesting with typical Pancoast syndrome. We report a case of a 71 years old male patient, presenting with features of Pancoast syndrome including Horner's syndrome with completed three cycles of chemotherapy resulting in partial response which concludes that small cell lung carcinoma has to be considered despite the clinical findings like pancoast syndrome.
Topics: Aged; Humans; Lung Neoplasms; Male; Pancoast Syndrome; Small Cell Lung Carcinoma
PubMed: 35210644
DOI: 10.31729/jnma.6620 -
Oncology Reports 2001A 60-year old man presented with Horner's syndrome, and acute right hand and lower extremity weakness. Chest X-ray and MRI revealed a right apical lung tumor (presumed...
A 60-year old man presented with Horner's syndrome, and acute right hand and lower extremity weakness. Chest X-ray and MRI revealed a right apical lung tumor (presumed to be a primary lung cancer), with brachial plexus infiltration and spinal cord compression. Emergent radiotherapy was initiated for spinal cord compression and a biopsy was obtained 24 h later. A careful review of pathology demonstrated a non-Hodgkin's lymphoma. The patient subsequently received chemotherapy, and is now in remission. This case illustrates the importance of a tissue diagnosis before initiating therapy for a Pancoast's tumor.
Topics: Carcinoma; Diagnosis, Differential; Horner Syndrome; Humans; Hypesthesia; Lung Neoplasms; Lymphoma, Non-Hodgkin; Male; Middle Aged; Muscle Weakness; Pancoast Syndrome; Spinal Cord Compression; Urinary Retention
PubMed: 11115591
DOI: 10.3892/or.8.1.165 -
Archives of Pathology Jul 1946
Topics: Bays; Humans; Lung Neoplasms; Neoplasms; Pancoast Syndrome; Thoracic Cavity
PubMed: 20995639
DOI: No ID Found -
Kyobu Geka. the Japanese Journal of... Oct 2005To study the clinical characteristics, treatment modalities, and outcome of patients with Pancoast tumors who underwent surgery over 11-year period. From January 1994 to...
To study the clinical characteristics, treatment modalities, and outcome of patients with Pancoast tumors who underwent surgery over 11-year period. From January 1994 to May 2005, 13 patients (12 men, 1 woman) with Pancoast tumor and histology of non-small cell lung cancer underwent surgical resection. Nine patients were received induction therapy (8 chemoradiation, 1 radiation only), and there were no treatment-related deaths. Twelve lobectomies, 1 pneumonectomy, and none of wedge resections or partial resection were performed. The number of ribs resected ranged from 2-6 (median 2.8). Chest wall reconstruction was performed in 2 patients, total vertebrectomy in 2, bronchoplasty in 2, and pulmonary arterioplasty in 1. Twelve of 13 patients (92.3%) had a complete resection. Pathologic stages were IB, IIB, IIIA and IIIB in 1, 7, 2, and 1, respectively, and pathologic complete responses was noted in 1. After a median follow-up of 34 months, the 3-year survival was 78.6% for all 13 patients and 85.7% for patients who had a complete resection. It is thought that induction chemoradiation for Pancoast tumors have potential to be able to become the treatment strategy in the future.
Topics: Adult; Carcinoma, Squamous Cell; Female; Humans; Male; Middle Aged; Pancoast Syndrome; Pneumonectomy; Survival Rate; Treatment Outcome
PubMed: 16235847
DOI: No ID Found -
Neurosurgical Focus Jun 2007Pancoast tumors are aggressive bronchogenic lesions of the lung apex that are rapidly fatal if untreated. Modern treatment includes induction chemotherapy and...
OBJECT
Pancoast tumors are aggressive bronchogenic lesions of the lung apex that are rapidly fatal if untreated. Modern treatment includes induction chemotherapy and radiotherapy prior to resection, but many authors also resect the T-1 nerve root (with or without the C-8 nerve root and the lower trunk of the brachial plexus) as part of the therapy, causing significant loss of hand function in many patients. The current authors determined whether a different approach allowing preservation of the brachial plexus and hand function could be adopted without compromising patient survival. An extensive historical review of Pancoast tumors is presented as a baseline for clinical comparison.
METHODS
Five patients harboring Pancoast tumors with brachial plexus involvement underwent surgery performed by both a neurosurgeon and thoracic surgeon. In all cases the tumor was resected from the brachial plexus using neurolysis while preserving the C-8 and T-1 nerve roots and lower trunk of the brachial plexus.
RESULTS
One patient died 3 years posttreatment; the other four patients remain alive and well 2 to 5 years postoperatively. Hand function improved or remained normal in all four survivors, with postoperative intrinsic hand muscle function being Louisiana State University Medical Center Grade 5 in each patient. These results (2-year survival rate of 100%) compare favorably with the Southwest Oncology Group Data (overall 2-year survival rate of 55%; 70% in patients who had undergone complete resection). With a minimum 2-year follow-up, 80% of patients remained alive and well, with normal hand function.
CONCLUSIONS
Although this patient series is small, the findings are extremely encouraging and suggest that the described treatment paradigm preserves survival as well as hand function in patients with Pancoast tumors.
Topics: Adult; Aged; Brachial Plexus; Female; Follow-Up Studies; Hand; Humans; Male; Middle Aged; Pancoast Syndrome; Peripheral Nervous System Neoplasms; Recovery of Function
PubMed: 17613206
DOI: No ID Found -
Chest Apr 1993Superior pulmonary sulcus carcinoma, or Pancoast's tumor, was first identified in 1932 by H. K. Pancoast, who described a small tumor at the apex of the lung producing a... (Review)
Review
Superior pulmonary sulcus carcinoma, or Pancoast's tumor, was first identified in 1932 by H. K. Pancoast, who described a small tumor at the apex of the lung producing a characteristic pain pattern and rapid, universal mortality. Despite early indications that this type of carcinoma was amenable to neither radiation nor surgery, the current treatment approach calls for irradiation therapy (3,000 rad over 2 to 3 weeks) followed by surgical resection of the chest wall, lower brachial plexus, and en bloc resection of the lung. In selected patients with negative mediastinal nodes, this approach has been associated with a 34% 5-year and a 29% 10-year survival.
Topics: Combined Modality Therapy; Humans; Pancoast Syndrome; Thoracic Neoplasms
PubMed: 8462326
DOI: 10.1378/chest.103.4_supplement.360s -
The New England Journal of Medicine Nov 1997
Review
Topics: Carcinoma, Bronchogenic; Humans; Neoplasm Staging; Pancoast Syndrome; Prognosis
PubMed: 9358132
DOI: 10.1056/NEJM199711063371907 -
Clinical Nuclear Medicine Oct 2004
Topics: Carcinoma, Non-Small-Cell Lung; Humans; Middle Aged; Pancoast Syndrome; Radionuclide Imaging; Radiopharmaceuticals; Reflex Sympathetic Dystrophy; Technetium Tc 99m Medronate; Upper Extremity
PubMed: 15365437
DOI: 10.1097/00003072-200410000-00008