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Medical Radiography and Photography 1985
Topics: Adolescent; Diagnosis, Differential; Female; Humans; Male; Middle Aged; Pancreas; Tomography, X-Ray Computed
PubMed: 4058286
DOI: No ID Found -
Deutsche Medizinische Wochenschrift... Jun 1986
Topics: Humans; Pancreas; Pancreatic Ducts; Pressure
PubMed: 3709377
DOI: No ID Found -
Archives Internationales de... 1990
Review
Topics: Animals; Autonomic Nervous System; Humans; Islets of Langerhans; Pancreas; Peptides
PubMed: 2196859
DOI: No ID Found -
The American Surgeon May 2003This paper brings the diagnosis and treatment of this interesting yet infrequent condition to contemporary standards through an assessment of past literature and a... (Review)
Review
This paper brings the diagnosis and treatment of this interesting yet infrequent condition to contemporary standards through an assessment of past literature and a re-evaluation of the problem in view of technological advances. Two cases of annular pancreas are cited with a review of the last 183 years of literature. Only 100 cases, however, were reported in enough detail to examine outcomes in general and to arrive at a reasonable conclusion in terms of recommendations for diagnosis and operative intervention in adult annular pancreas. Two observations are brought to light. Despite all present diagnostic tools including endoscopic retrograde cholangiopancreatography diagnosis at best is made in only 60 per cent of patients preoperatively. Intraoperative expertise remains the best diagnostic modality available to date. Enteroenterostomy seems to be the intervention of choice for a multitude of anatomic and physiologic reasons and with a wide array of surgical options available when additional factors need to be addressed.
Topics: Digestive System Diseases; Female; Humans; Male; Middle Aged; Pancreas
PubMed: 12769212
DOI: No ID Found -
Nederlands Tijdschrift Voor Geneeskunde Sep 1983
Topics: Acute Disease; Cholangiopancreatography, Endoscopic Retrograde; Humans; Male; Middle Aged; Pancreas; Pancreatitis; Recurrence
PubMed: 6633701
DOI: No ID Found -
Bulletin Et Memoires de L'Academie... 1977
Review
Topics: Animals; Humans; Pancreas; Peptides; Proteins; Rats; Receptors, Cell Surface; Somatostatin
PubMed: 206300
DOI: No ID Found -
Lancet (London, England) Dec 1978
Topics: Humans; Microtomy; Pancreas; Pancreatic Polypeptide
PubMed: 82163
DOI: 10.1016/s0140-6736(78)92181-5 -
The Journal of International Medical... Dec 2019Because of the complicated blood supply and vascular structure of the pancreas, blood vessel reconstruction and reshaping are generally required during pancreas...
OBJECTIVE
Because of the complicated blood supply and vascular structure of the pancreas, blood vessel reconstruction and reshaping are generally required during pancreas transplantation. We modified the vascular preparation procedure for the donor pancreas (i.e., no vascular reconstruction was performed) based on experiences in our department and in other domestic and international transplantation centers.
METHODS
Twelve donor pancreas preparations without vascular reconstruction were performed. The patch (Carrel patch), celiac trunk, and superior mesenteric artery were preserved as arterial inflow channels for the donor pancreas. The common hepatic artery and the gastroduodenal artery were transected at a site 0.5 cm away from the bifurcation. The bifurcated portion was preserved for the donor liver. The stumps of the gastroduodenal artery and common hepatic artery were then ligated. The portal vein was transected in the middle of the hepatoduodenal ligament during separation of the liver and pancreas. The partial portal vein preserved with the pancreas was used as the outflow channel of the donor pancreas.
RESULTS
The transplanted pancreas functioned well in the recipients, and no vascular complications were reported.
CONCLUSION
The overall efficacy of pancreas transplantation without vascular reconstruction has been improved.
Topics: Adult; Female; Humans; Kidney Function Tests; Kidney Transplantation; Male; Middle Aged; Pancreas; Pancreas Transplantation; Tissue Donors; Treatment Outcome
PubMed: 31500486
DOI: 10.1177/0300060519870894 -
Cell Reports May 2019In vitro differentiation of pluripotent cells into β cells is a promising alternative to cadaveric-islet transplantation as a cure for type 1 diabetes (T1D). During...
In vitro differentiation of pluripotent cells into β cells is a promising alternative to cadaveric-islet transplantation as a cure for type 1 diabetes (T1D). During the directed differentiation of human embryonic stem cells (hESCS) by exogenous factors, numerous genes that affect the differentiation process are turned on and off autonomously. Manipulating these reactions could increase the efficiency of differentiation and provide a more complete control over the final composition of cell populations. To uncover in vitro autonomous responses, we performed single-cell RNA sequencing on hESCs as they differentiate in spherical clusters. We observed that endocrine cells and their progenitors exist beside one another in separate compartments that activate distinct genetic pathways. WNT pathway inhibition in the endocrine domain of the differentiating clusters reveals a necessary role for the WNT inhibitor APC during islet formation in vivo. Accordingly, WNT inhibition in vitro causes an increase in the proportion of differentiated endocrine cells.
Topics: Cell Differentiation; Humans; Pancreas; Stem Cells; Wnt Signaling Pathway
PubMed: 31116975
DOI: 10.1016/j.celrep.2019.04.083 -
Bulletin de La Societe Des Sciences... 1987
Review
Topics: Adult; Cholangiopancreatography, Endoscopic Retrograde; Female; Humans; Pancreas
PubMed: 3329061
DOI: No ID Found