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Rinsho Shinkeigaku = Clinical Neurology Jul 1994A case of multiple sclerosis (MS) associated with granulomatous panuveitis was reported. A 45-year-old woman developed diplopia in 1972, at age 24, optic neuritis in... (Review)
Review
A case of multiple sclerosis (MS) associated with granulomatous panuveitis was reported. A 45-year-old woman developed diplopia in 1972, at age 24, optic neuritis in 1974 and acute transverse myelopathy in 1981. Subsequently, while being under our care with the clinical diagnosis of MS, right abducens palsy in 1989, deterioration of paraparesis with remission in 1991, and weakness of left arm in 1992 occurred. CSF study revealed high IgG index and brain MRI showed multiple abnormal intensity areas in the deep white matter and periventricular areas bilaterally. On the beginning in March, 1993, she noticed left hazy vision and the ophthalmological examinations revealed marked mutton-fat like keratic precipitates, posterior synechiae, cells and flare in anterior chamber, retinal phlebitis and snow ball vitreous opacity. Granulomatous panuveitis was diagnosed and treated by topical steroid with improvement within two months. During this episode, no neurological deterioration was seen. Granulomatous uveitis in MS was rarely documented in the literatures, but this seems to be more common in women, mildly symptomatic or asymptomatic and responds well to topical steroid treatment.
Topics: Female; Granuloma; Humans; Middle Aged; Multiple Sclerosis; Panuveitis
PubMed: 7955734
DOI: No ID Found -
Revista de La Facultad de Ciencias... 2016The Vogt-Koyanagi-Harada syndrome is a disease with dermatological, neurologic and auditory findings, associated with a bilateral granulomatous panuveitis. We present...
The Vogt-Koyanagi-Harada syndrome is a disease with dermatological, neurologic and auditory findings, associated with a bilateral granulomatous panuveitis. We present the case of a 42-year-old woman who started with ophthalmic manifestations, and in a late follow-up she developed the characteristic dermatological findings.
Topics: Adult; Female; Humans; Panuveitis; Retinal Detachment; Uveomeningoencephalitic Syndrome; Vitiligo
PubMed: 27420148
DOI: No ID Found -
Ophthalmic Surgery, Lasers & Imaging... Oct 2015A 20-year-old white woman presented with bilateral acute visual loss (visual acuity: 20/60), panuveitis, and exudative retinal detachments 3 weeks after a second dose of...
A 20-year-old white woman presented with bilateral acute visual loss (visual acuity: 20/60), panuveitis, and exudative retinal detachments 3 weeks after a second dose of quadrivalent human papillomavirus (HPV4) vaccine. She was treated with oral prednisolone for 6 weeks and responded rapidly. By week 4, vision had normalized and clinical signs resolved. Uveitis after HPV4 vaccination has been reported in two cases. Although the differential diagnosis includes Harada disease, temporal correlation with HPV4 and definitive response to a short course of treatment implicate the vaccine in this case. Vaccine-induced uveitis is rare and difficult to distinguish from coincidental autoimmune disease.
Topics: Administration, Oral; Choroid; Exudates and Transudates; Female; Fluorescein Angiography; Glucocorticoids; Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18; Humans; Panuveitis; Papillomavirus Infections; Prednisolone; Retinal Detachment; Tomography, Optical Coherence; Ultrasonography; Vaccination; Vision Disorders; Visual Acuity; Young Adult
PubMed: 26469238
DOI: 10.3928/23258160-20151008-11 -
European Journal of Ophthalmology Mar 2024Panuveitis is a serious inflammatory disease. Setae are fibers produced by many insects and plants. Many case reports have described caterpillar and spider fibers...
INTRODUCTION
Panuveitis is a serious inflammatory disease. Setae are fibers produced by many insects and plants. Many case reports have described caterpillar and spider fibers entering the eye. These hairs are covered with tiny barbs that help them enter and migrate into the eye tissue, leading to severe inflammation. Normally, they are buried mainly in the conjunctiva and cornea. However, in the present case, they entered the posterior segment of the eye, which is very rare.
CASE DESCRIPTION
A female patient presented with a complaint of repeated foreign body sensation, redness, pain, and photophobia in the left eye for 9 years following initial exposure to caterpillars. She visited the doctor in January after aggravation of symptoms. Slit-lamp examination, ultrasound biomicroscopy, ultrasound B-scan, fluorescein angiography, and indocyanine green angiography revealed the presence of a foreign body in the vitreous, which caused discomfort in the patient's left eye and subsequently, panuveitis of the left eye. The symptoms improved significantly after foreign body removal using vitrectomy. Microscopic examination revealed that the foreign body was caterpillar setae.
CONCLUSION
Clinicians should be more vigilant about history of contact with caterpillars while examining uveitis that has recurred for many years. Identification of the root cause of the disease can ensure better treatment.
Topics: Animals; Female; Humans; Sensilla; Eye Foreign Bodies; Lepidoptera; Panuveitis; Uveitis; Cornea
PubMed: 37723890
DOI: 10.1177/11206721231203262 -
Arquivos Brasileiros de Oftalmologia 2021
Topics: Acquired Immunodeficiency Syndrome; Anti-Bacterial Agents; Humans; Panuveitis; Rifabutin
PubMed: 34550225
DOI: 10.5935/0004-2749.202100118 -
Ocular Immunology and Inflammation May 2021: Herein, we report a case of bilateral neuroretinitis and panuveitis in a patient recovered from coronavirus disease 2019 (COVID-19).: A 37-year-old male patient with a...
: Herein, we report a case of bilateral neuroretinitis and panuveitis in a patient recovered from coronavirus disease 2019 (COVID-19).: A 37-year-old male patient with a history of recovered COVID-19, which was confirmed with nasopharyngeal reverse transcriptase polymerase chain reaction (RT-PCR) for Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), about one-month ago was referred with one-week history of bilateral severe vision loss. Visual acuity was counting fingers, and bilateral retinitis and panuveitis were revealed in ocular examination. The result of the vitreous sample using RT-PCR was positive for SARS-CoV-2 and negative for viruses and . The patient was successfully treated with corticosteroid.: We report a case of bilateral neuroretinitis and panuveitisin a recovered COVID-19 patient and positive RT-PCR of the vitreous sample. It is suggested to apply intraocular sampling and evaluation for COVID-19 in patients with the new-onset of uveitis and/or retinitis during the pandemic.
Topics: Adult; COVID-19; Eye Infections, Viral; Fluorescein Angiography; Fundus Oculi; Humans; Male; Pandemics; Panuveitis; RNA, Viral; Retina; Retinitis; SARS-CoV-2; Tomography, Optical Coherence; Uvea; Visual Acuity
PubMed: 33830840
DOI: 10.1080/09273948.2021.1894457 -
Ophthalmology. Retina Apr 2020
Topics: Choroid; Humans; Male; Middle Aged; Multifocal Choroiditis; Panuveitis; Tomography, Optical Coherence; Visual Acuity
PubMed: 32273110
DOI: 10.1016/j.oret.2019.11.013 -
Ocular Immunology and Inflammation Apr 2023During the Coronavirus Disease 2019 (COVID-19) pandemic, we have witnessed increase in number of reports of a known uveitic entity being associated with severe acute...
During the Coronavirus Disease 2019 (COVID-19) pandemic, we have witnessed increase in number of reports of a known uveitic entity being associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Causal relation is yet to be proven for many reports. Perhaps, occurrence of a previously known region-specific endemic disease or closely resembling manifestations of a known disease in a non-endemic region during the COVID-19 pandemic might suggest a causal relationship. Epidemic retinitis (ER) or post fever retinitis is such condition with geographic variation. Occurrence of ER or ER-like manifestations in a non-endemic country during the pandemic should instigate further studies to consider SARS-CoV-2 as a causative organism.
Topics: Humans; COVID-19; SARS-CoV-2; Pandemics; Chorioretinitis; Retinitis; Panuveitis
PubMed: 35258394
DOI: 10.1080/09273948.2022.2039212 -
BMC Ophthalmology Feb 2022Extranodal natural killer/T-cell lymphoma (ENKTL), nasal type, generally affects the orbit by direct extension. It can even rarely present as severe intraocular...
BACKGROUND
Extranodal natural killer/T-cell lymphoma (ENKTL), nasal type, generally affects the orbit by direct extension. It can even rarely present as severe intraocular inflammation mimicking endophthalmitis. Delayed diagnosis and treatment are frequently reported.
CASE PRESENTATION
A 43-year-old woman presented with 2-month blurred vision in her left eye. Ocular examination revealed hypopyon panuveitis. She was initially diagnosed with endogenous endophthalmitis, which proved irresponsive to antimicrobial therapy. High-dose prednisolone was given afterward, but this failed to stop the development and continuous progression of ocular inflammation. The diagnosis of ENKTL was finally confirmed from the pathological findings of oral ulcers and cervical lymph nodes and chemotherapy was prescribed. After the first cycle of chemotherapy, the patient's ocular inflammation subsided. Unfortunately, her left eye became phthisis with progressive visual loss within 9 months following the diagnosis.
CONCLUSIONS
The diagnosis of intraocular ENKTL is frequently delayed, which can lead to severe problems for treatment as the disease is aggressive with a poor prognosis. It can be found not only in elderly patients but also in a middle-aged individual. In patients with ocular inflammation, a thorough systemic evaluation and histopathological examination of the associated systemic findings is extremely helpful and may reveal the cause of the ocular inflammation, including revealing possible ENKTL.
Topics: Adult; Aged; Eye Neoplasms; Female; Humans; Intraocular Lymphoma; Killer Cells, Natural; Lymphoma, Extranodal NK-T-Cell; Middle Aged; Panuveitis
PubMed: 35100995
DOI: 10.1186/s12886-022-02277-2 -
Journal of Pediatric Ophthalmology and... 2009A 5-year-old child developed panuveitis with choroidal lesions. Topical steroid medications were insufficient to control the inflammation long-term. Granuloma annulare...
A 5-year-old child developed panuveitis with choroidal lesions. Topical steroid medications were insufficient to control the inflammation long-term. Granuloma annulare was subsequently diagnosed in association with the uveitis. Systemic immunosuppression with methotrexate was eventually required to control the skin lesions and uveitis. Uveitis associated with granuloma annulare may present with choroidal lesions and panuveitis in children.
Topics: Child, Preschool; Choroid Diseases; Granuloma Annulare; Humans; Immunosuppressive Agents; Male; Methotrexate; Panuveitis
PubMed: 19213278
DOI: 10.3928/01913913-20090101-02