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The Bulletin of Tokyo Dental College Nov 2003We report a rare case of a papillary cystadenoma arising from the upper lip. This tumor was not distinctly encapsulated and had proliferated replacing the ductal...
We report a rare case of a papillary cystadenoma arising from the upper lip. This tumor was not distinctly encapsulated and had proliferated replacing the ductal epithelium. Mast cells were found not only in the stroma but also in the oncocytic epithelial layer. There was a strong immunoreaction with mitochondrial antibody in the epithelial layer. Only one case (0.9%) of papillary cystadenoma has occurred among the 110 benign intraoral salivary gland tumors seen in our hospital from 1966 through September 2003.
Topics: Cystadenoma, Papillary; Humans; Lip Neoplasms; Male; Mast Cells; Middle Aged; Salivary Gland Neoplasms; Salivary Glands, Minor
PubMed: 15103919
DOI: 10.2209/tdcpublication.44.213 -
Archives of Otolaryngology (Chicago,... Jan 1964
Topics: Adenolymphoma; Cystadenoma; Cystadenoma, Papillary; Palate; Pathology; Prognosis; Surgical Procedures, Operative
PubMed: 14063794
DOI: 10.1001/archotol.1964.00750030019004 -
Histopathology Jul 2015
Topics: Adult; Biomarkers, Tumor; Cystadenoma, Papillary; Epididymis; Humans; Male; Testicular Neoplasms
PubMed: 25406742
DOI: 10.1111/his.12617 -
Archives of Pathology & Laboratory... Dec 2001Serous cystadenoma of the pancreas is an uncommon neoplasm that occasionally exhibits papillary differentiation. The cytomorphologic structure of pancreatic serous...
Serous cystadenoma of the pancreas is an uncommon neoplasm that occasionally exhibits papillary differentiation. The cytomorphologic structure of pancreatic serous cystadenoma has been rarely described, and, to our knowledge, such papillary morphologic structure has never been reported on fine-needle aspiration cytologic examination. We present a case of serous cystadenoma of the pancreas in a 77-year-old woman. Endoscopic ultrasonography showed a well-demarcated solid/cystic mass in the midbody of the pancreas, suggestive of solid pseudopapillary tumor. Aspiration cytologic examination, performed under endoscopic ultrasound guidance, showed a predominantly papillary epithelial neoplasm consistent with the radiologic impression. Gross and histologic examination of the excised specimen revealed a pancreatic serous cystadenoma with multifocal papillae. This case illustrates the cytomorphologic structure of serous cystadenoma that presents with prominent papillary differentiation on aspiration cytologic examination. The unusual cytologic appearance of this tumor introduces significant diagnostic challenges to the pathologist. Serous cystadenoma must be included in the differential diagnosis of pancreatic neoplasms with papillary morphologic structure as evaluated by fine-needle aspiration cytologic examination.
Topics: Aged; Biomarkers, Tumor; Biopsy, Needle; Cystadenoma, Papillary; Cystadenoma, Serous; Endosonography; Female; Humans; Immunohistochemistry; Pancreatic Neoplasms
PubMed: 11735697
DOI: 10.5858/2001-125-1591-SCOTPW -
Head and Neck Pathology Dec 2016The aim of this study was to compare the immunoexpression of epithelial mucins (MUCs) in salivary duct cysts, papillary cystadenomas, and mucoepidermoid carcinomas and...
The aim of this study was to compare the immunoexpression of epithelial mucins (MUCs) in salivary duct cysts, papillary cystadenomas, and mucoepidermoid carcinomas and to evaluate if any of these markers could be useful for differentiating between mucoepidermoid carcinoma and papillary cystadenoma. We also sought to validate the p63 expression pattern found to differentiate between mucoepidermoid carcinoma and papillary cystadenoma. Immunoexpression of MUC1, MUC2, MUC4, MUC7, and p63 was studied and quantified in 22 mucoepidermoid carcinomas, 12 papillary cystadenomas, and 3 salivary duct cysts. The immunohistochemical evaluation was collectively performed by 3 oral pathologists. Scores and trends in proportions were assessed using the nonparametric Wilcoxon-Mann-Whitney rank sum test. Mucoepidermoid carcinomas, papillary cystadenomas, and salivary duct cysts demonstrated variable MUC expression patterns. All tumors were positive for p63 immunoexpression with p63 labeling in salivary duct cysts and papillary cystadenomas (15/15) limited to the basal layers of the cystic spaces, whereas in mucoepidermoid carcinomas (22/22) the p63 labeling extended throughout the suprabasal layers (p < 0.001). This study adds more confirmatory data to validate that the reactivity pattern of p63 protein can be used in distinguishing between papillary cystadenoma and low-grade mucoepidermoid carcinoma. Although positive reactivity in a tumor with MUC1 and MUC4 was inconclusive, negative reactivity suggests the diagnosis of a benign PC or SDC.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinoma, Mucoepidermoid; Cystadenoma, Papillary; Diagnosis, Differential; Female; Humans; Immunohistochemistry; Male; Membrane Proteins; Middle Aged; Mucins; Salivary Gland Neoplasms
PubMed: 27278378
DOI: 10.1007/s12105-016-0735-4 -
Aktuelle Urologie Jun 2018Testicular and paratesticular cystadenomas arise from an oviduct-like structure, which, morphologically, is almost identical with the ovarian surface epithelium. These...
Testicular and paratesticular cystadenomas arise from an oviduct-like structure, which, morphologically, is almost identical with the ovarian surface epithelium. These are very rare benign tumours of adults. They present as asymptomatic cystic lesions. Bilateral paratesticular cystadenomas are associated with the Von-Hippel-Lindau syndrome and may be associated with infertility. Most cystadenomas are benign, but a few cases of malignant transformation of embryonic remnants have been reported in the appendix testis, including cases of adenocarcinoma, cystadenocarcinoma, and a Müllerian-type epithelial tumour with a low malignant potential. We report the case of a 74-year-old man with a rare paratesticular cystadenoma of the male adnexa.
Topics: Aged; Cystadenoma, Papillary; Diagnosis, Differential; Humans; Male; Testicular Neoplasms; Testis
PubMed: 28511230
DOI: 10.1055/s-0043-101214 -
Urology Aug 2018Association between papillary cystadenoma of the epididymis (PCE) and Von Hippel-Lindau Disease (VHLD) is well known and stronger for bilateral tumors. Unilateral PCE...
Association between papillary cystadenoma of the epididymis (PCE) and Von Hippel-Lindau Disease (VHLD) is well known and stronger for bilateral tumors. Unilateral PCE occurs either as a sporadic tumor without evidence of VHLD or in the context of a known diagnosis of VHLD, indeed it has never been reported as the first manifestation of VHLD. In contrast, we report the case of a boy with an apparently isolated, unilateral PCE that resulted to be the first manifestation of an unknown VHLD. Thus, we recommend screening for VHLD in patients with a new diagnosis of unilateral PCE, especially if the patients are young.
Topics: Adolescent; Cystadenoma, Papillary; Epididymis; Genital Neoplasms, Male; Humans; Male; von Hippel-Lindau Disease
PubMed: 29729363
DOI: 10.1016/j.urology.2018.04.025 -
Oral Surgery, Oral Medicine, and Oral... Jun 1966
Topics: Cystadenoma; Diagnosis, Differential; Humans; Male; Middle Aged; Mouth Mucosa; Mouth Neoplasms; Salivary Gland Neoplasms
PubMed: 5219669
DOI: 10.1016/0030-4220(66)90102-2 -
Oral Surgery, Oral Medicine, and Oral... Oct 1956
Topics: Cystadenoma, Papillary; Humans; Neoplasms; Palatal Neoplasms; Palate; Papilloma
PubMed: 13370094
DOI: 10.1016/0030-4220(56)90064-0 -
The Journal of Urology Feb 2001
Topics: Aged; Cystadenoma, Papillary; Humans; Male; Testicular Neoplasms
PubMed: 11176423
DOI: 10.1097/00005392-200102000-00053