-
The British Journal of Ophthalmology Feb 1984A case of intraocular paragonimiasis is reported in a 13-year-old Chinese boy. The disease manifested as repeated attacks of acute intraocular pain associated with...
A case of intraocular paragonimiasis is reported in a 13-year-old Chinese boy. The disease manifested as repeated attacks of acute intraocular pain associated with panuveitis. A combination of inflammatory reaction and ocular findings mimicking both perforating and contusion injuries caused by the migration of the fluke within the eye characterises the infection. The living fluke was successfully extracted from the anterior chamber and identified as Paragonimus westermani.
Topics: Adolescent; Eye Diseases; Humans; Male; Paragonimiasis; Uveitis
PubMed: 6691960
DOI: 10.1136/bjo.68.2.85 -
Memorias Do Instituto Oswaldo Cruz Nov 2014A review of national and international publications on paragonimiasis in Ecuador, epidemiological records from the Ministry of Public Health and unpublished research... (Review)
Review
A review of national and international publications on paragonimiasis in Ecuador, epidemiological records from the Ministry of Public Health and unpublished research data was conducted to summarise the current status of the parasite/disease. The purpose of the review is to educate physicians, policy-makers and health providers on the status of the disease and to stimulate scientific investigators to conduct further research. Paragonimiasis was first diagnosed in Ecuador 94 years ago and it is endemic to both tropical and subtropical regions in 19 of 24 provinces in the Pacific Coast and Amazon regions. Paragonimus mexicanus is the only known species in the country, with the mollusc Aroapyrgus colombiensis and the crabs Moreirocarcinus emarginatus, Hypolobocera chilensis and Hypolobocera aequatorialis being the primary and secondary intermediate hosts, respectively. Recent studies found P. mexicanus metacercariae in Trichodactylus faxoni crabs of the northern Amazon. Chronic pulmonary paragonimiasis is commonly misdiagnosed and treated as tuberculosis and although studies have demonstrated the efficacy of praziquantel and triclabendazole for the treatment of human infections, neither drug is available in Ecuador. Official data recorded from 1978-2007 indicate an annual incidence of 85.5 cases throughout the 19 provinces, with an estimated 17.2% of the population at risk of infection. There are no current data on the incidence/prevalence of infection, nor is there a national control programme.
Topics: Animals; Anthelmintics; Astacoidea; Brachyura; Chronic Disease; Ecuador; Humans; Lung Diseases, Parasitic; Metacercariae; Neglected Diseases; Paragonimiasis; Paragonimus
PubMed: 25410987
DOI: 10.1590/0074-0276140042 -
The Southeast Asian Journal of Tropical... 1997In Korea, soybean-sauce soaked freshwater crabs (kejang) have been a favorite delicacy when eating a bowl of rice. This traditional food has been a main source of human... (Review)
Review
In Korea, soybean-sauce soaked freshwater crabs (kejang) have been a favorite delicacy when eating a bowl of rice. This traditional food has been a main source of human paragonimiasis. Until the late 1960s, human paragonimiasis had been prevalent; at least two million people had contracted the infection as determined by intradermal tests. About 40% of these were egg positive. In the turmoil of the green revolution and industrialization in the 1970s/1980s, ecological damage occurred widely. In many streams, populations of snail and crustacean hosts were reduced to levels almost of extinction. Population reduction of the intermediate hosts was followed by lowered endemicity. Attitudes of people, changed during the period, also reduced chances of paragonimiasis. Survey data in the 1990s indicated that prevalence of human paragonimiasis has lowered to about one 100th of that in the early 1970s. In a referral system, however, about one hundred clinical cases have been diagnosed annually by antibody test (ELISA), undertaken for clinical differentiation from tuberculosis. At least 10% of freshwater crabs sold in local markets are infected with the metacercariae. Paragonimiasis control has benefited in Korea mainly by the untoward effects of water pollution. To place P. westermani infections as enzootic, health education and surveillance systems should have a priority.
Topics: Animals; Brachyura; Humans; Incidence; Korea; Paragonimiasis; Snails
PubMed: 9656345
DOI: No ID Found -
The Lancet. Infectious Diseases Oct 2023
Topics: Humans; Child; Paragonimiasis; Cough; Tuberculosis, Pulmonary; Lung Diseases, Parasitic
PubMed: 37775222
DOI: 10.1016/S1473-3099(23)00273-6 -
Scandinavian Journal of Infectious... 2006A 64-y-old female previously treated for lung fluke presented with shortness of breath and moderate left pleural effusion. Thoracentesis was performed and milky pleural... (Review)
Review
A 64-y-old female previously treated for lung fluke presented with shortness of breath and moderate left pleural effusion. Thoracentesis was performed and milky pleural effusion was obtained. Paragonimus ova and rhomboidal cholesterol crystals were found. Paragonimiasis was diagnosed, and the patient was treated with praziquantel 25 mg/kg/d.
Topics: Anthelmintics; Cholesterol; Chylothorax; Female; Humans; Middle Aged; Paragonimiasis; Pleural Effusion; Praziquantel; Treatment Outcome
PubMed: 16709545
DOI: 10.1080/00365540500372853 -
Journal of Gastrointestinal Surgery :... Mar 2018Paragonimiasis is a parasitic lung infection caused by lung flukes of the genus Paragonimus. Ectopic infection may occur but rarely involves the liver. Here, we report a...
Paragonimiasis is a parasitic lung infection caused by lung flukes of the genus Paragonimus. Ectopic infection may occur but rarely involves the liver. Here, we report a case of hepatic paragonimiasis in a Chinese man who was initially suspected to have hepatocellular carcinoma. He had been previously diagnosed with chronic hepatitis B. No specific symptoms or abnormal blood test results were observed, except for a significant rise in serum alfa-fetoprotein. Magnetic resonance imaging revealed a 12-cm mass with inhomogeneous signal intensity at the left lobe of the liver. Laparoscopic left hemihepatectomy was performed. He was finally diagnosed as hepatic paragonimiasis upon pathological examination and antibody serology. The postoperative course was uneventful. He received a standard course of praziquantel and recovered well. Our case is unique in its tumor-like characteristic and protrudes the difficulty of differential diagnosis with both benignant and malignant hepatic diseases by imaging studies or non-specific symptoms. Hepatic paragonimiasis is unusual; however, it should be considered in the differential diagnosis of liver malignancy by clinicians.
Topics: Adult; Animals; Anthelmintics; Carcinoma, Hepatocellular; Diagnosis, Differential; Hepatectomy; Hepatitis B, Chronic; Humans; Laparoscopy; Liver Diseases, Parasitic; Liver Neoplasms; Magnetic Resonance Imaging; Male; Paragonimiasis; Praziquantel
PubMed: 29340921
DOI: 10.1007/s11605-018-3683-3 -
Ryoikibetsu Shokogun Shirizu 1999
Review
Topics: Animals; Antiplatyhelmintic Agents; Diagnosis, Differential; Humans; Lung Diseases, Parasitic; Paragonimiasis; Paragonimus; Praziquantel; Prognosis
PubMed: 10201266
DOI: No ID Found -
Ryoikibetsu Shokogun Shirizu 1999
Review
Topics: Animals; Antiplatyhelmintic Agents; Diagnosis, Differential; Humans; Lung Diseases, Parasitic; Paragonimiasis; Paragonimus; Praziquantel; Prognosis
PubMed: 10201265
DOI: No ID Found -
Archivos Argentinos de Pediatria Dec 2019Paragonimiasis is a parasite infection caused by several species of Paragonimus, a trematode that is transmitted through the consumption of raw or undercooked crabs and...
Paragonimiasis is a parasite infection caused by several species of Paragonimus, a trematode that is transmitted through the consumption of raw or undercooked crabs and that has been found in the subtropical areas of America, Asia and Africa. This infection mainly affects the lungs, causing clinical and radiological manifestations very similar to pulmonary tuberculosis, so it should always be included in the differential diagnosis. We present the case of a 7-year-old school patient, hospitalized with the diagnosis of pulmonary paragonimiasis, who had a favorable evolution after receiving treatment with triclabendazole.
Topics: Animals; Antiplatyhelmintic Agents; Child; Female; Humans; Lung Diseases, Parasitic; Paragonimiasis; Paragonimus; Triclabendazole
PubMed: 31758906
DOI: 10.5546/aap.2019.e659 -
The American Journal of Tropical... Apr 2023Paragonimiasis is a food-born zoonotic parasitosis caused by Paragonimus spp. Six cases of reemerging paragonimiasis within the Karan hill-tribe near the Thai-Myanmar...
Paragonimiasis is a food-born zoonotic parasitosis caused by Paragonimus spp. Six cases of reemerging paragonimiasis within the Karan hill-tribe near the Thai-Myanmar border were evaluated to review clinical manifestations, predisposing factors, and treatment regimens. All patients tested positive for paragonimiasis eggs and presented with an array of symptoms, including chronic cough, hemoptysis, peripheral eosinophilia, and thoracic radiograph abnormalities. All fully recovered after a 2- to 5-day course of 75 to 80 mg/kg/day praziquantel. We conclude that paragonimiasis should be considered during differential diagnoses to promote early treatment and to prevent misdiagnosis of reemerging or sporadic cases. This applies particularly to endemic regions and high-risk groups known to habitually consume raw or undercooked intermediate or paratenic hosts.
Topics: Animals; Humans; Paragonimiasis; Thailand; Praziquantel; Paragonimus; Hemoptysis
PubMed: 36848893
DOI: 10.4269/ajtmh.22-0708