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Collegium Antropologicum Jun 2005The aim of the study was to investigate the clinical association of multiple sclerosis and pars planitis (or intermediate uveitis), as well as to determine the incidence...
The aim of the study was to investigate the clinical association of multiple sclerosis and pars planitis (or intermediate uveitis), as well as to determine the incidence of pars planitis in multiple sclerosis patients. During the period of one year authors examined 42 patients with multiple sclerosis divided into two groups. First group consisted of 23 patients with history of optic neuritis and the second group consisted of 19 patients who have never had optic neuritis. The mean age of patients in the first group was 31.7 +/- 5.1 years and in the second group 29.1 +/- 8.1 years. Pars planitis was found in 12 patients with multiple sclerosis. Age, sex and degree of neurological disability had no influence on the appearance of pars planitis. Although optic neuritis is considered to be the most common ocular manifestation of multiple sclerosis, the significant number of patients with multiple sclerosis has pars planitis.
Topics: Adult; Age Factors; Female; Humans; Incidence; Male; Multiple Sclerosis; Pars Planitis; Sex Factors
PubMed: 16117323
DOI: No ID Found -
Clinical & Experimental Ophthalmology Apr 2001To compare the symptoms, visual acuities and complications found in childhood onset pars planitis, with those seen in adult onset disease. (Comparative Study)
Comparative Study
PURPOSE
To compare the symptoms, visual acuities and complications found in childhood onset pars planitis, with those seen in adult onset disease.
METHOD
The records of 26 patients (52 eyes) with idiopathic pars planitis seen at a tertiary care clinic were reviewed. The study design allowed comparison of follow-up visual acuities for the adult onset and childhood onset groups at 2 years and 5 years from the time of initial diagnosis.
RESULTS
The visual acuity at the time of initial diagnosis, at 2 years' follow up and at 5 years' follow up was worse for children than for adults, but this difference only reached statistical significance at 2 years' follow up (6/10 vs 6/7; P = 0.026). When looking at correlation coefficients between age and acuity, the same trend was observed at all time intervals, only reaching statistical significance with initial visual acuities (r = 0.32; P = 0.019). Adults had a tendency to complain more at presentation of blurred vision and floaters than children. Complication rates were similar for both groups.
CONCLUSION
The study presents data supporting the idea that patients presenting with idiopathic pars planitis in childhood have a worse visual acuity both at initial diagnosis and at follow up than those presenting in adulthood. This is a long-suspected finding that has not previously been demonstrated.
Topics: Adolescent; Adult; Age of Onset; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Male; Pars Planitis; Retrospective Studies; Visual Acuity
PubMed: 11341451
DOI: No ID Found -
Graefe's Archive For Clinical and... Jun 2022
Topics: Adalimumab; Humans; Multiple Sclerosis; Pars Planitis; Uveitis, Intermediate
PubMed: 35088114
DOI: 10.1007/s00417-021-05528-y -
Retina (Philadelphia, Pa.) 1983Ophthalmologists do not consider pars planitis to occur on a familial basis. The development of pars planitis in nine members of four different families is reported....
Ophthalmologists do not consider pars planitis to occur on a familial basis. The development of pars planitis in nine members of four different families is reported. Affected family members include twin sisters, a mother and daughter, two brothers, and a sister and two brothers from the same family. This suggests that a common hereditary and/or environmental factor contributed to the disease in these patients.
Topics: Adolescent; Adult; Child; Child, Preschool; Ciliary Body; Diseases in Twins; Female; Follow-Up Studies; Humans; Male; Uveitis; Visual Acuity
PubMed: 6635352
DOI: 10.1097/00006982-198300330-00006 -
Ocular Immunology and Inflammation Mar 2003To describe the clinical manifestations of classic pars planitis (CPP) in Mexican patients. We report here the most frequent complications, medical and surgical...
PURPOSE
To describe the clinical manifestations of classic pars planitis (CPP) in Mexican patients. We report here the most frequent complications, medical and surgical treatment, and visual prognosis.
MATERIAL AND METHODS
A retrospective, descriptive case series examined the clinical features, complications, and treatment (medical and surgical) of CPP patients seen at the Inflammatory Eye Disease Clinic from January 1990 to September 1999.
RESULTS
One hundred and sixty patients met inclusion criteria for the study. Mean age at presentation was 10 years and males were more frequently affected. Both eyes were affected in 84.4% of the cases. The most frequent complaint was decreased visual acuity. Initial visual acuity (VA) ranged from no light perception to 20/20 (mean 20/50), and mean final VA was 20/30. The most frequent clinical manifestations were vitritis (99.7%), snowballs (99.3%), retinal vasculitis (89.2%), and snowbanks (63.1%). The most common complications were cystoid macular edema (63.4%) and cataract (47.5%). Periocular corticosteroids were used in 97.5% of cases, systemic corticosteroids in 68.1%, and other immunosuppressive drugs in 21.3%.
CONCLUSIONS
CPP in the Mexican population is more frequent in males and usually presents in patients less than 14 years of age. It is typically bilateral, and the most common symptom is decreased visual acuity. The most important clinical findings are located in the vitreous and retina. Cataract and cystoid macular edema are the most frequent complications. Treatment comprises periocular and systemic corticosteroids or other immunosuppressive drugs.
Topics: Administration, Topical; Adolescent; Adult; Anti-Inflammatory Agents; Cataract; Child; Child, Preschool; Eye Diseases; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Macular Edema; Male; Mexico; Pars Planitis; Retinal Vasculitis; Retrospective Studies; Vision Disorders; Visual Acuity; Vitreous Body
PubMed: 12854027
DOI: 10.1076/ocii.11.1.53.15583 -
Ocular Immunology and Inflammation Sep 2002
Topics: Adult; Crohn Disease; Female; Humans; Pars Planitis
PubMed: 12789592
DOI: 10.1076/ocii.10.3.157.15597 -
European Journal of Ultrasound :... Oct 2002To determine the value of high frequency ultrasound biomicroscopy (UBM) in the assessment of pars planitis, and in particular to correlate UBM findings and...
OBJECTIVE
To determine the value of high frequency ultrasound biomicroscopy (UBM) in the assessment of pars planitis, and in particular to correlate UBM findings and ophthalmoscopy findings.
METHODS
All patients with pars planitis were identified from the uveitis database of the Department of Ophthalmology, University of Aberdeen. Fifteen consecutive patients (age 14-52 years) underwent complete ophthalmological examination. UBM was performed at a sound frequency of 50 MHz on 17 eyes of 10 patients to determine the extent of disease. UBM findings were evaluated by two investigators in a blinded fashion and graded from 0 to 3 according to the following grading criteria: 0=no cells, 1=mild cells, 2=marked cells, 3=organization of cells. Opthalmoscopy findings were also graded using the same criteria. UBM and ophthalmoscopy findings were independently graded and compared.
RESULTS
We found a good inter-observer correlation for the UBM grading of pars planitis (rho=0.86). There was no significant difference in the grading of pars planitis by indirect ophthalmoscopy as compared to grading by UBM (P>0.05).
CONCLUSION
UBM appears to be a valuable and reliable diagnostic technique for the evaluation of patients with pars planitis and may be useful especially in patients with media opacities to diagnose and/or monitor efficacy of treatment.
Topics: Adolescent; Adult; Child; Humans; Middle Aged; Ophthalmoscopy; Pars Planitis; Pilot Projects; Ultrasonography
PubMed: 12423740
DOI: 10.1016/s0929-8266(02)00035-6 -
F1000prime Reports 2014Pediatric uveitis is a topic of special interest not only because of the unique diagnostic and therapeutic challenges but also because of the lifetime burden of vision... (Review)
Review
Pediatric uveitis is a topic of special interest not only because of the unique diagnostic and therapeutic challenges but also because of the lifetime burden of vision loss if the problem is not adequately treated, as well as the economic and psychological toll on the family. Often, uveitis in children is discovered as part of a routine eye exam; this silent, insidious inflammation can be difficult to treat and can lead to further complications if not handled skillfully. Corticosteroids have long been the mainstay of therapy; however, the significant associated side effects mandate a corticosteroid-sparing therapeutic regimen in pursuit of remission. In this review, we cover the therapeutic options for pediatric uveitis, specifically focusing on the most common non-infectious varieties, juvenile idiopathic arthritis-associated uveitis and pars planitis.
PubMed: 24991418
DOI: 10.12703/P6-41 -
European Journal of Ophthalmology May 2022To report a case of a Hispanic girl with late-onset Retinoblastoma (Rb) who was misdiagnosed as a pars planitis prior to referral. Nearly 95% of all Rb cases are...
INTRODUCTION
To report a case of a Hispanic girl with late-onset Retinoblastoma (Rb) who was misdiagnosed as a pars planitis prior to referral. Nearly 95% of all Rb cases are detected before age 5, and this patient was 8 years-old.
METHODS
Case report of a late-onset Retinoblastoma with anterior chamber (AC) involvement plus the presence of an Ahmed valve. The patient had a history of a couple of months of topical therapy comprising medication for glaucoma, systemic steroids, and a filtration surgery (Ahmed valve), after that a biopsy was performed prior to referral. Upon arrival at our clinic, we performed an examination under anesthesia (EUA) and a B-scan ultrasound (US).
RESULTS
Unilateral Retinoblastoma with an Ahmed valve in an AC filled with Rb seeds was diagnosed with the EUA and US in the left eye. An orbital exenteration with map biopsies of the left orbital cavity was performed with confirmation by histopathology of a poorly differentiated endophytic retinoblastoma with Bruch's membrane invasion. Follow-up sessions were then arranged as well as subsequent systemic chemotherapy cycles.
CONCLUSION
Given the rare incidence of retinoblastoma in children older than 5 years old, it can be easily mistaken for other differential diagnoses and treated with filtration surgeries that could put the patient's life at risk. In this report, late-onset Rb diagnosis is highlighted as a differential diagnosis in children and adults with atypical uveitis, which required a multidisciplinary approach.
Topics: Anterior Chamber; Child; Child, Preschool; Female; Hispanic or Latino; Humans; Pars Planitis; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Uveitis, Intermediate
PubMed: 33567900
DOI: 10.1177/1120672121994487 -
Medical Journal, Armed Forces India Jan 2001
PubMed: 27365593
DOI: 10.1016/S0377-1237(01)80106-4