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Journal of Pediatric Hematology/oncology Nov 2021Extracranial pure malignant rhabdoid tumors (MRT) are aggressive tumors that carry a poor prognosis. Bladder MRTs are very rare and only 8 cases have been reported... (Review)
Review
BACKGROUND
Extracranial pure malignant rhabdoid tumors (MRT) are aggressive tumors that carry a poor prognosis. Bladder MRTs are very rare and only 8 cases have been reported previously.
OBSERVATION
We present a case of a child with bladder MRT. Despite the aggressive nature of the bladder tumor, it was successfully treated with bladder-sparing surgery, adjuvant radiotherapy, and chemotherapy.
CONCLUSIONS
Our case, and review of 8 previously reported cases, suggests that bladder MRT seems to behave less aggressively when compared with other extracranial MRTs, and bladder preserving surgery should be considered when feasible.
Topics: Chemotherapy, Adjuvant; Child, Preschool; Combined Modality Therapy; Cystectomy; Humans; Male; Prognosis; Radiotherapy, Adjuvant; Rhabdoid Tumor; Urinary Bladder Neoplasms
PubMed: 33031160
DOI: 10.1097/MPH.0000000000001963 -
Urologia Aug 2018Glomus tumors arising in the urinary bladder are extremely rare, and only two cases have been reported in the English Literature. We present a case of a 58-year-old man... (Review)
Review
Glomus tumors arising in the urinary bladder are extremely rare, and only two cases have been reported in the English Literature. We present a case of a 58-year-old man with an asymptomatic mass of the anterior wall of the bladder that measured 2.5 × 2.5 cm. Endoscopic excision was performed, and the tumor was diagnosed as symplastic glomus tumor. The patient finally underwent robotic-assisted partial cystectomy, and he remains healthy without any recurrence to date. After reviewing this case and previous reports, we analyzed the clinicopathologic features and treatment options for this rare neoplasm.
Topics: Cystectomy; Glomus Tumor; Humans; Male; Middle Aged; Robotic Surgical Procedures; Urinary Bladder Neoplasms
PubMed: 28106242
DOI: 10.5301/uro.5000214 -
Der Urologe. Ausg. A Apr 2015In many cases radical cystectomy is not feasible in patients suffering from muscle-invasive bladder cancer due to advanced age of the patient or limiting comorbidities... (Review)
Review
BACKGROUND
In many cases radical cystectomy is not feasible in patients suffering from muscle-invasive bladder cancer due to advanced age of the patient or limiting comorbidities which increase the perioperative risk. A further group of patients decline radical cystectomy due to potential postoperative complications and the resulting impairment in the quality of life.
OBJECTIVES
This article provides an overview of alternative therapeutic concepts to radical cystectomy in muscle-invasive bladder cancer.
MATERIAL AND METHODS
The study involved a database analysis and gives a discussion of clinical trials concerning alternative therapeutic concepts for muscle-invasive bladder cancer treatment strategies.
RESULTS
Transurethral resection, open partial cystectomy, radiotherapy, chemotherapy and combined therapeutic regimens are available as alternatives to radical cystectomy.
CONCLUSION
Radical cystectomy is the accepted standard of care in the treatment of muscle-invasive bladder cancer but in selected patients, established alternative methods can also be offered. A comprehensive patient information and counseling is therefore necessary to find the best therapeutic option in each individual case. Salvage cystectomy is a therapeutic option in cases of failure of organ-preserving treatment.
Topics: Chemoradiotherapy; Combined Modality Therapy; Cystectomy; Evidence-Based Medicine; Humans; Muscle Neoplasms; Neoplasm Invasiveness; Treatment Outcome; Urinary Bladder Neoplasms
PubMed: 25895563
DOI: 10.1007/s00120-015-3775-6 -
Archivos Espanoles de Urologia Jul 2019Bladder leiomyomas are rare benign tumors; their common presentation are irritative and obstructive urinary symptoms. The treatment is complete surgical resection.
UNLABELLED
Bladder leiomyomas are rare benign tumors; their common presentation are irritative and obstructive urinary symptoms. The treatment is complete surgical resection.
OBJECTIVE
To present our experience in the diagnosis and the treatment of bladder leiomyoma.
METHODS
A series of three clinical cases.
RESULTS
In our series, two patients were women and one was man. The mean age was 33 years. Two women presented with irritative urinary symptoms and palpation of a pelvic mass, and the man was asymptomatic. Ultrasound showed the presence of an adnexal mass with left hydronephrosis in a female patient, bladder tumor in another female patient and pelvic mass of unknown etiology in the male patient. CT scan and MRI demonstrated the bladder origin of the lesion. A biopsy confirmed a bladder leiomyoma. Surgical treatment was partial cystectomy in all patients, and in one of them, nephrectomy was performed. During follow-up, all patients were asymptomatic and without recurrence.
CONCLUSIONS
Imaging studies guide to diagnosis. Transurethral resection is recommended in lesions smaller than 3 cm. and enucleation or partial cystectomy in larger lesions. Prognosis is good.
Topics: Adult; Cystectomy; Female; Humans; Leiomyoma; Male; Neoplasm Recurrence, Local; Urinary Bladder Neoplasms
PubMed: 31274128
DOI: No ID Found -
BMC Urology May 2023Comparing the long-term tumor control results of partial cystectomy(PC)and radical cystectomy(RC)in the treatment of muscle-invasive bladder cancer, and to explore the...
OBJECTIVES
Comparing the long-term tumor control results of partial cystectomy(PC)and radical cystectomy(RC)in the treatment of muscle-invasive bladder cancer, and to explore the feasible method of bladder preservation therapy (BPT)in patients with MIBC.
METHODS
We retrospectively analyzed the clinical data of 102 patients with muscle-invasive bladder cancer in our hospital between January 2012 and December 2018, of whom 32 cases in the partial cystectomy group and 70 cases in the radical cystectomy group. We performed a comparative analysis of patient general information, perioperative-related indicators and postoperative follow-up data, comparing OS, PFS, and DSS at 1, 2, 3, 4, and 5 years in both groups, and comparing tumour recurrence and metastasis in postoperative patients.
RESULTS
All the 102 cases in this study were successfully completed. Partial cystectomy group and Radical cystectomy group median operating time (169.50(130.00 ~ 225.25) min and 420.00(343.75 ~ 483.75) min, p < 0.001), median intraoperative blood loss was (100(50 ~ 100)ml and 400(200 ~ 1000)ml, p < 0.001), median perioperative blood transfusion volume (0(0 ~ 0)ml and 600(150.00 ~ 906.25)ml, p < 0.001), median total hospital stay (18(14.25 ~ 20.00) and 24.5(20.00 ~ 34.25) days, p < 0.001), median preoperative preparation time (7(4.25 ~ 8.00) and 10(8.00 ~ 13.00) days, p < 0.001), median postoperative hospital stay (9(8.00 ~ 13.50) and 14(11.00 ~ 21.25) days, p < 0.001), the incidence of perioperative blood transfusion was (15.6% and 75.7%, p < 0.001), the incidence of surgical complications was(28.1%(9/32) and 50.0%(35/70), p = 0.033), average hospitalization cost ((26435.76 ± 9877.82) yuan and (58464.36 ± 19753.13) yuan, p < 0.001), the differences were statistically significant (p < 0.05). Perioperative mortality (0 vs. 2.9%(2/70), p = 1), and OS at 1, 2, 3, 4, and 5 years after surgery were (80.0%, 59.8%, 56.1%, 51.0%, 44.6% vs. 76.5%, 67.4%, 64.9%, 57.9%, 52.6%, p = 0.524), PFS (68.2%, 64.6%, 60.3%, 54.8%, 54.8% vs. 82.7%, 78.3%, 75.4%, 67.3%, 62.1%, p = 0.259). DSS (89.9%, 72.4%, 68.6%, 68.6%, 62.4% vs. 87.3%, 83.4%, 80.9%, 73.6%, 68.0%, p = 0.424), and the incidence of tumor recurrence or metastasis was (40.0%(12/30) vs. 25.4%(16/63), p = 0.151), the differences were not statistically significant (p > 0.05).
CONCLUSION
In patients with limited solitary T2N0M0 and T3N0M0 muscle-invasive bladder cancer, partial cystectomy plus bladder instillations treatment can achieve comparable tumour control to radical cystectomy. However, patients in the PC group have significant advantages in terms of operative time, intraoperative bleeding, intraoperative and postoperative blood transfusion, preoperative preparation time, total hospital stay, postoperative recovery time, operative costs and operative complications. This option may be considered for such patients with a need for bladder preservation.
Topics: Humans; Urinary Bladder; Cystectomy; Administration, Intravesical; Retrospective Studies; Neoplasm Recurrence, Local; Urinary Bladder Neoplasms; Muscles; Treatment Outcome
PubMed: 37170081
DOI: 10.1186/s12894-023-01267-w -
Urologia Internationalis 2023This study aimed to compare the survival outcomes between trimodal therapy (TT) and partial cystectomy (PC) in muscle-invasive bladder cancer (MIBC) patients.
OBJECTIVE
This study aimed to compare the survival outcomes between trimodal therapy (TT) and partial cystectomy (PC) in muscle-invasive bladder cancer (MIBC) patients.
METHODS
The data of 13,096 patients with MIBC diagnosed between 2004 and 2015 were retrieved from the Surveillance, Epidemiology, and End Results database. Among them, 4,041 patients underwent TT and 1,670 patients underwent PC. Propensity score matching was performed to balance the characteristics between the 2 treatment groups. A multivariate Cox regression analysis model and a competing risk model were used to evaluate overall survival (OS) and cancer-specific survival. Cumulative incidence survival curves were obtained using the Kaplan-Meier method.
RESULTS
Results of multivariate Cox analysis before propensity score matching showed that the TT group had a 31% reduction in cause-specific survival relative to the PC group (HR: 0.69, 95% CI: 0.61-0.78, p < 0.001) and a 28% reduction in OS (HR: 0.72, 95% CI: 0.66-0.79, p < 0.001). After propensity score matching, the 2 groups yielded 972 patients, with 3-year cause-specific survival rates of 54.1% and 68.5% in the TT group and the PC group, respectively.
CONCLUSIONS
Patients who underwent PC had a better prognosis than those who received TT. In addition, for MIBC patients who required bladder-sparing therapy, advanced age (≥80 years), pathological type of squamous cell carcinoma, and tumor stage of T3-4, N2-3, and M1 were independent poor prognostic factors.
Topics: Humans; Aged, 80 and over; Urinary Bladder; Cystectomy; Chemoradiotherapy; Urinary Bladder Neoplasms; Prognosis; Muscles; Neoplasm Invasiveness; Treatment Outcome
PubMed: 34818263
DOI: 10.1159/000518562 -
Effect of transurethral partial cystectomy with 2.0 μm laser in treating superficial bladder cancer.Journal of B.U.ON. : Official Journal... 2020To compare and analyze the efficacy and safety of transurethral partial cystectomy with 2.0 μm laser and transurethral resection of bladder tumor (TURBT) in treating...
PURPOSE
To compare and analyze the efficacy and safety of transurethral partial cystectomy with 2.0 μm laser and transurethral resection of bladder tumor (TURBT) in treating patients with superficial bladder cancer.
METHODS
The clinical data of 130 patients with superficial bladder cancer were divided into two groups based on different treatments, with 65 patients in each group, and treated with transurethral partial cystectomy with 2.0 μm laser and TURBT separately. Then, operation conditions such as intraoperative blood loss, operation time, in-dwelling time of urinary catheter and length of hospital stay were recorded and compared between the two groups. Finally, the tumor recurrence in the patients was followed up and recorded.
RESULTS
The operation time (p<0.001) and length of hospital stay (p=0.013) were remarkably shorter, and the intraoperative blood loss (p<0.001) was notably smaller in laser group than those in TURBT group. Laser group had an evidently lower total incidence rate of complications than TURBT group (p=0.005). The patients were reexamined by cystoscopy at 4 weeks after operation, and the biopsy results indicated that there were markedly more cases of positive findings in TURBT groupthan those in laser group (no positive findings) (p=0.033). However, laser group exhibited distinctly decreased postoperative levels of IL-6 and TNF-α but an obviously increased IL-10 level compared with TURBT group (p<0.001). Besides, after 6-40 months of follow-up for all the patients, the total recurrence rate was prominently lower in laser group than that in TURBT group (p=0.006).
CONCLUSIONS
In contrast with TURBT, transurethral partial cystectomy with 2.0 μm laser for superficial bladder cancer can significantly reduce the operation time and intraoperative blood loss, improve the operative effect, induce fewer postoperative complications and cause milder body injury and inflammatory response at the same time, which is worthy of clinical promotion.
Topics: Cystectomy; Female; Humans; Laser Therapy; Male; Middle Aged; Treatment Outcome; Urinary Bladder Neoplasms
PubMed: 33455118
DOI: No ID Found -
BMC Surgery Jun 2019The postoperative and survival outcomes of patients with primary advanced colorectal cancer who undergo partial versus total cystectomy have not been adequately... (Comparative Study)
Comparative Study
BACKGROUND
The postoperative and survival outcomes of patients with primary advanced colorectal cancer who undergo partial versus total cystectomy have not been adequately compared, as studies of this topic are rare and comprise relatively small cohorts. This study aimed to investigate the short- and long-term outcomes of patients who underwent en bloc partial or total cystectomy for primary advanced colorectal cancer that was suspected of adhering to or invading the urinary bladder.
METHODS
The study included 90 patients who underwent various degrees of cystectomy between 1993 and 2013 to treat locally advanced primary colorectal cancer that was suspected of involving the urinary bladder. Patients in whom total cystectomy was performed solely because of prostate-invading lower rectal cancer were excluded. Data on patient characteristics and their short- and long-term outcomes were collected retrospectively to evaluate differences between partial cystectomy (the P group; n = 72) and total cystectomy (the T group; n = 18). Postoperative and oncologic outcomes were also analyzed.
RESULTS
The T group had significantly greater operating times than the P group (median, 572 vs. 346 min); blood loss volume was also greater in the T group (median, 3092 vs. 1112 mL). The postoperative overall complication rate was significantly greater in the T group than in the P group (94.4% vs. 51.4%). With a median follow-up duration of 62 months, local recurrences were observed in 22.2 and 6.9% of patients in the T and P groups, respectively. On multivariate Cox regression analyses using partial cystectomy as the reference, total cystectomy was independently associated with poorer local recurrence-free survival (hazard ratio [HR], 4.0 95% confidence interval [CI], 1.1-15.0), relapse-free survival (HR, 2.9; 95% CI, 1.2-6.9), and overall survival (HR, 2.1; 95% CI, 1.0-4.3).
CONCLUSIONS
Patients who undergo en bloc total cystectomy for locally advanced colorectal cancers have worse postoperative and oncologic outcomes than those who undergo partial cystectomy.
Topics: Adult; Aged; Aged, 80 and over; Colorectal Neoplasms; Cystectomy; Female; Humans; Male; Middle Aged; Multivariate Analysis; Neoplasm Recurrence, Local; Neoplasm Staging; Operative Time; Postoperative Complications; Proportional Hazards Models; Retrospective Studies; Survival Rate; Urinary Bladder Neoplasms
PubMed: 31208384
DOI: 10.1186/s12893-019-0522-8 -
Archivio Italiano Di Urologia,... Mar 2019Leiomyoma of the bladder is a very rare disorder that accounts for 0.43% of all bladder neoplasms. Although the pathophysiology of the bladder leiomyoma is unknown,...
Leiomyoma of the bladder is a very rare disorder that accounts for 0.43% of all bladder neoplasms. Although the pathophysiology of the bladder leiomyoma is unknown, there are some theories on it. The patients can be asymptomatic; when present, clinical symptoms (lower urinary tract symptoms and\or hematuria), are associated with tumor size and location. For diagnosis, imaging plays an important role: ultrasound, computed tomography (CT) scan and magnetic resonance imaging (MRI) are the examinations most frequently performed. Treatment consists of surgical removal of the tumor, and the prognosis is excellent.
Topics: Adult; Cystectomy; Humans; Leiomyoma; Magnetic Resonance Imaging; Male; Tomography, X-Ray Computed; Ultrasonography; Urinary Bladder Neoplasms
PubMed: 30932431
DOI: 10.4081/aiua.2019.1.51 -
BMC Urology Feb 2023Mesh erosion into the bladder after hernioplasty is sparsely reported in literature and may be underestimated in clinical practice. We report a case of a patient who was...
BACKGROUND
Mesh erosion into the bladder after hernioplasty is sparsely reported in literature and may be underestimated in clinical practice. We report a case of a patient who was referred to our department due to recurrent urinary tract infections caused by a bladder stone due to mesh migration after inguinal hernia repair 22 years ago.
CASE PRESENTATION
A 67-year-old male patient was referred from the outpatient urologist for transurethral resection of the prostate in September 2021 due to recurrent urinary tract infections caused by benign prostatic enlargement and bladder stone formation. During the operation, parts of the stone were smashed and the prostate was resected. Additionally, a mesh eroding from the bladder roof was detected masqueraded by the stone. A computed tomography scan, which was performed afterwards, revealed a 20 × 25 mm mesh migration into the bladder after inguinal hernia repair on the left with concomitant stone adhesion to the mesh. After revealing patient history, an inguinal hernia repair with mesh implantation was done 22 years ago. A robotic assisted partial cystectomy and mesh excision was performed. The patient recovered well.
CONCLUSION
Mesh erosion into the urinary bladder after hernia repair can occur up to two decades after the primary operation. Although it is rarely reported, it can be a possible cause for recurrent urinary tract infections and therefore a mentionable complication after inguinal hernia operation. Robotic-assisted laparoscopic partial cystectomy with complete excision of the mesh is an option for definitive treatment.
Topics: Male; Humans; Aged; Urinary Bladder; Cystectomy; Hernia, Inguinal; Urinary Bladder Calculi; Robotic Surgical Procedures; Surgical Mesh; Transurethral Resection of Prostate
PubMed: 36855070
DOI: 10.1186/s12894-023-01197-7