-
Contributions To Microbiology 2000
Review
Topics: Animals; DNA Replication; DNA, Viral; Gene Transfer Techniques; Humans; Parvovirus; Virus Replication
PubMed: 10941578
DOI: 10.1159/000060337 -
Emerging Infectious Diseases Feb 2022In 1978, canine parvovirus type 2 originated from spillover of a feline panleukopenia-like virus, causing a worldwide pandemic of enteritis and myocarditis among canids....
In 1978, canine parvovirus type 2 originated from spillover of a feline panleukopenia-like virus, causing a worldwide pandemic of enteritis and myocarditis among canids. In 2020, the virus was identified in pigs in South Dakota, USA, by PCR, sequencing, in situ hybridization, and serology. Genetic analysis suggests spillover from wildlife.
Topics: Animals; Animals, Wild; Cats; Dogs; Feline Panleukopenia; Feline Panleukopenia Virus; Parvoviridae Infections; Parvovirus, Canine; South Dakota; Swine
PubMed: 35076011
DOI: 10.3201/eid2802.211681 -
The Journal of Clinical Investigation Apr 1994
Comparative Study
Topics: Animals; Humans; Macaca fascicularis; Parvovirus; Parvovirus B19, Human
PubMed: 8163639
DOI: 10.1172/JCI117110 -
The Veterinary Record Apr 1980
Topics: Animals; Biological Evolution; Dogs; Feline Panleukopenia Virus; Parvoviridae
PubMed: 6254227
DOI: 10.1136/vr.106.17.392 -
Emerging Infectious Diseases Mar 2010Porcine plasma and factor VIII preparations were screened for parvovirus 4 (PARV)-like viruses. Although the prevalence of PARV4-like viruses in plasma samples was...
Porcine plasma and factor VIII preparations were screened for parvovirus 4 (PARV)-like viruses. Although the prevalence of PARV4-like viruses in plasma samples was relatively low, viruses appeared to be concentrated during manufacture of factor VIII. PARV4-like viruses from human and porcine origins coevolved likewise with their hosts.
Topics: Animals; Biological Products; DNA, Viral; Factor VIII; Humans; Parvoviridae Infections; Parvovirus; Plasma; Sequence Analysis, DNA; Swine; Swine Diseases
PubMed: 20202447
DOI: 10.3201/eid1603.090746 -
Virology Monographs. Die Virusforschung... 1976
Review
Topics: Adenoviridae; Animals; Antigens, Viral; Cell Line; Cricetinae; Cytopathogenic Effect, Viral; DNA, Viral; Feline Panleukopenia Virus; Haplorhini; Humans; Mice; Minute Virus of Mice; Molecular Weight; Nucleic Acid Conformation; Parvoviridae; Parvovirus; Rats; Terminology as Topic; Viral Proteins; Virus Cultivation; Virus Diseases; Virus Replication
PubMed: 181899
DOI: No ID Found -
Bing Du Xue Bao = Chinese Journal of... Nov 2015Until now, more than seventeen parvovirus have been reported which can infect mammals and poultries. The infected cells appeared different properties of apoptosis and... (Review)
Review
Until now, more than seventeen parvovirus have been reported which can infect mammals and poultries. The infected cells appeared different properties of apoptosis and death, present a typical cytopathic effect. NS1 is a major nonstructural protein of parvovirus, with a conservative structure and function, which plays an important role in the viral life cycle. In addition to the influence on viral replication, the NS1 also participates in apoptosis induced by viruses. Parvovirus induced apoptosis which is mainly mediated by mitochondrial pathway, this review summarized the latest research progresses of parvovirus induced apoptosis.
Topics: Animals; Apoptosis; Humans; Parvoviridae Infections; Parvovirus; Viral Nonstructural Proteins
PubMed: 26951015
DOI: No ID Found -
Virus Research Dec 2013Porcine parvovirus (PPV), a member of the genus Parvovirus, family Parvoviridae, is a significant causative agent in porcine reproductive failure, causing serious...
Porcine parvovirus (PPV), a member of the genus Parvovirus, family Parvoviridae, is a significant causative agent in porcine reproductive failure, causing serious economic losses in the swine industry. Previous phylogenetic studies based on the NS1 or VP2 genes indicated that current PPV strains diverged 30 years ago and that VP2 was under neutral or positive selection. Our analysis of NS1, VP2 and complete ORFs indicated that the most recent common ancestor of PPV strains existed about 250 years ago and that the 127-nt repeat in the 3'NTR was present in viruses of some subclades that evolved about 80 years ago. Nucleotide substitution rates of NS1 and VP2 genes were 3.03 × 10(-5) and 1.07 × 10(-4), respectively. Both the NS1 and VP2 proteins were under purifying selection and recombination did not contribute to the genetic diversity of PPV. As expected, surface amino acids are hydrophilic and make up the majority of mutations in the VP2 protein; residues in VP2 interfaces were substituted gradually, often in conjunction with complementary substitutions in the neighboring VP2.
Topics: Animals; Computational Biology; Evolution, Molecular; Genetic Variation; Mutation Rate; Parvovirus, Porcine; Phylogeny; Selection, Genetic; Sequence Analysis, DNA; Swine; Viral Proteins
PubMed: 24050995
DOI: 10.1016/j.virusres.2013.09.014 -
Viruses Jul 2022Waterfowl parvovirus (WPFs) has multiple effects on the intestinal tract, but the effects of recombinant Muscovy duck parvovirus (rMDPV) have not been elucidated. In...
Waterfowl parvovirus (WPFs) has multiple effects on the intestinal tract, but the effects of recombinant Muscovy duck parvovirus (rMDPV) have not been elucidated. In this study, 48 one-day-old Muscovy ducklings were divided into an infected group and a control group. Plasma and ileal samples were collected from both groups at 2, 4, 6, and 8 days post-infection (dpi), both six ducklings at a time. Next, we analyzed the genomic sequence of the rMDPV strain. Results showed that the ileal villus structure was destroyed seriously at 4, 6, 8 dpi, and the expression of ZO-1, Occludin, and Claudin-1 decreased at 4, 6 dpi; 4, 6, 8 dpi; and 2, 6 dpi, respectively. Intestinal cytokines IFN-α, IL-1β and IL-6 increased at 6 dpi; 8 dpi; and 6, 8 dpi, respectively, whereas IL-2 decreased at 6, 8 dpi. The diversity of ileal flora increased significantly at 4 dpi and decreased at 8 dpi. The bacteria Ochrobactrum and Enterococcus increased and decreased at 4, 8 dpi; 2, 4 dpi, respectively. Plasma MDA increased at 2 dpi, SOD, CAT, and T-AOC decreased at 2, 4, 8 dpi; 4, 8 dpi; and 4, 6, 8 dpi, respectively. These results suggest that rMDPV infection led to early intestinal barrier dysfunction, inflammation, ileac microbiota disruption, and oxidative stress.
Topics: Animals; Ducks; Parvoviridae Infections; Parvovirinae; Parvovirus; Poultry Diseases
PubMed: 35891451
DOI: 10.3390/v14071471 -
PLoS Biology Nov 2022Parvoviruses (family Parvoviridae) are small DNA viruses that cause numerous diseases of medical, veterinary, and agricultural significance and have important...
Parvoviruses (family Parvoviridae) are small DNA viruses that cause numerous diseases of medical, veterinary, and agricultural significance and have important applications in gene and anticancer therapy. DNA sequences derived from ancient parvoviruses are common in animal genomes and analysis of these endogenous parvoviral elements (EPVs) has demonstrated that the family, which includes twelve vertebrate-specific genera, arose in the distant evolutionary past. So far, however, such "paleovirological" analysis has only provided glimpses into the biology of ancient parvoviruses and their long-term evolutionary interactions with hosts. Here, we comprehensively map EPV diversity in 752 published vertebrate genomes, revealing defining aspects of ecology and evolution within individual parvovirus genera. We identify 364 distinct EPV sequences and show these represent approximately 200 unique germline incorporation events, involving at least five distinct parvovirus genera, which took place at points throughout the Cenozoic Era. We use the spatiotemporal and host range calibrations provided by these sequences to infer defining aspects of long-term evolution within individual parvovirus genera, including mammalian vicariance for genus Protoparvovirus, and interclass transmission for genus Dependoparvovirus. Moreover, our findings support a model of virus evolution in which the long-term cocirculation of multiple parvovirus genera in vertebrates reflects the adaptation of each viral genus to fill a distinct ecological niche. Our findings show that efforts to develop parvoviruses as therapeutic tools can be approached from a rational foundation based on comparative evolutionary analysis. To support this, we published our data in the form of an open, extensible, and cross-platform database designed to facilitate the wider utilisation of evolution-related domain knowledge in parvovirus research.
Topics: Animals; Vertebrates; Ecology; Acclimatization; Agriculture; Parvovirus; Mammals
PubMed: 36445931
DOI: 10.1371/journal.pbio.3001867