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The Veterinary Quarterly Sep 2016In veterinary medicine, the management of malignant skin wounds is highly challenging. We conducted a study on seven case animals (four dogs and three cats) which...
In veterinary medicine, the management of malignant skin wounds is highly challenging. We conducted a study on seven case animals (four dogs and three cats) which presented with malignant skin wounds. All seven animals had signs and symptoms which were controlled following treatment with a modified Mohs paste. Upon obtaining informed consent from their owners, the animals requiring management of malignant wounds were enrolled in this study. The modified Mohs paste was prepared by mixing zinc chloride, zinc oxide starch powder, glycerin, and distilled water. The modified Mohs paste was topically applied to and left to remain on the malignant wounds for one hour, under controlled conditions. Once the paste was removed, the wounds were irrigated with a solution of sterile saline. At the first examination, the wounds of each animal were observed for signs of exudate, malodor, and bleeding. In every case, visible improvement was observed immediately after the modified Mohs paste treatment. Specifically, the size of the malignant wounds, and the number of times the dressing gauze required changing, significantly decreased (p < 0.05 and p < 0.01, respectively). The open malignant skin wounds caused by mammary gland tumors disappeared in two cases. The Mohs paste has been shown to be a viable option for the palliative treatment in canine and feline malignant skin wound management.
Topics: Administration, Topical; Animals; Cats; Chlorides; Dogs; Female; Japan; Male; Ointments; Palliative Care; Treatment Outcome; Wound Healing; Zinc Compounds
PubMed: 26828294
DOI: 10.1080/01652176.2015.1130880 -
Microscopy Research and Technique Feb 2019The purpose of this study was to evaluate mineral content of root canal dentin after treatment with different antibiotic pastes including the mixture of metronidazole,...
The purpose of this study was to evaluate mineral content of root canal dentin after treatment with different antibiotic pastes including the mixture of metronidazole, ciprofloxacin, doxycycline, cefaclor, amoxicillin, or minocycline. Fifty extracted maxillary canine teeth were randomly divided into five groups (n = 10 teeth for each group). Root canals were prepared Reciproc rotary files. Canals were irrigated using 5 ml 5% NaOCl and 1 ml 15% EDTA. Each tooth in all groups were longitudinally splitted into two pieces as a control and experimental samples. Each experimental group received following antibiotic paste; double antibiotic paste (DAP) and triple antibiotic paste with doxycycline (TAPd), TAP with cefaclor (TAPc), TAP with amoxicillin (TAPa), and TAP with minocycline (TAPm) for 21 days. The Ca, P, Mg, Ca, and K levels, and the Ca/P ratio was analyzed by a scanning electron microscope (SEM) equipped using a Bruker energy-dispersive X-Ray (EDX) detector. Data were analyzed with independent samples t-test, one-way anova, and Duncan tests. Ca and Ca/P ratio showed a statistically significant increase TAP with amoxicillin and cefaclor (p < .05). DAP, TAPd, and TAPm did not change the mineral levels (p > .05). TAPa and TAPc with increased the Ca level and Ca/P ratio of the root canal dentin which consequently positively influences the revascularization process.
Topics: Anti-Bacterial Agents; Cuspid; Dental Pulp Cavity; Dentin; Humans; Minerals; Ointments; Spectrometry, X-Ray Emission
PubMed: 30511430
DOI: 10.1002/jemt.23155 -
Gan To Kagaku Ryoho. Cancer &... Sep 2008A 45-year-old woman with a local recurrence on her left chest wall discharged massive exudates. At every gauze exchange, blood was still oozing out. After using Mohs...
A 45-year-old woman with a local recurrence on her left chest wall discharged massive exudates. At every gauze exchange, blood was still oozing out. After using Mohs paste twice, the surface had been fixed chemically and dried up, so she did not have to exchange gauze, and there was no more bleeding. A 55-year-old woman was suffering massive exudates and offensive smell from her right primary breast cancer that formed a massive bulge with a deep ulcer in the center. Because her serum hemoglobin declined to 4.4 g/mL due to continuous bleeding, she needed to undergo blood transfusion. After using Mohs paste twice, the bleeding stopped almost completely. Now she uses Mohs paste by herself at home at her convenience. A 69 year-old woman suffered from an offensive odor and continuous bleeding from a local recurrence in the skin of her abdomen. A single use of Mohs paste relieved her from bleeding and the smell. Three patients had experienced no adverse events except mild pain and their QOL improved considerably. Mohs paste is in the hope of improving the QOL for the breast cancer patients with local advanced, unresectable skin lesions.
Topics: Aged; Breast Neoplasms; Female; Humans; Middle Aged; Neoplasm Staging; Ointments
PubMed: 18799906
DOI: No ID Found -
Biomedizinische Technik. Biomedical... Aug 2017The aim of this study was a comparison of shear bond strength (SBS) on tooth enamel of different primers combined with the adhesive paste Transbond XT.
AIM
The aim of this study was a comparison of shear bond strength (SBS) on tooth enamel of different primers combined with the adhesive paste Transbond XT.
MATERIALS AND METHODS
Forty bovine teeth were used in order to create 40 test blocks. The blocks were divided into four groups of 10 blocks each: group A - sample primer (SP); group B - Opal Seal (OS); group C - Transbond Plus SEP (TSEP); group D - Transbond XT Primer (TXT). After surface preparation and application of the primer, respectively, two stainless steel brackets were fixed on each tooth by using Transbond XT. Accordingly, 80 brackets were debonded (n=20). Shear bond strength and adhesive remnant index (ARI) scores were evaluated. Statistical analyses were performed by using the Student's t-test and Mann-Whitney U test.
RESULTS
All tested groups revealed high shear bond strength in a similar size range. There were no significant differences between the groups concerning shear bond strength. The ARI scores of group C showed significantly lower ARI scores (0 and 1) than that of group D. Apart from that there was no statistical difference.
CONCLUSION
In combination with the adhesive paste Transbond XT, all tested primers were suitable for fixing orthodontic brackets. The primers could be changed according to the clinical situation.
Topics: Animals; Bisphenol A-Glycidyl Methacrylate; Cattle; Dental Cements; Dental Enamel; Dental Stress Analysis; Humans; Materials Testing; Ointments; Orthodontic Brackets; Resin Cements; Shear Strength
PubMed: 28640749
DOI: 10.1515/bmt-2016-0241 -
The Journal of Prosthetic Dentistry Feb 1985
Topics: Dental Stress Analysis; Denture Bases; Ointments
PubMed: 3856673
DOI: 10.1016/0022-3913(85)90136-2 -
Journal of Palliative Medicine May 2018The skin fixative used in Mohs chemosurgery contains zinc chloride and is referred to as Mohs paste (MP). However, MP shows a remarkable change in rheological...
BACKGROUND
The skin fixative used in Mohs chemosurgery contains zinc chloride and is referred to as Mohs paste (MP). However, MP shows a remarkable change in rheological characteristics after its preparation.
OBJECTIVE
To prepare an MP with stable rheological characteristics, we prepared a modified MP (mMP) using zinc oxide 10% single ointment (Zn), which is an oil-based ointment.
METHODS
We evaluated mMP by determining its rheological characteristics, depth of tissue fixation, and observation of the tissue surface after treatment.
RESULTS
The viscosity of mMP increased after three months. However, the treatment-dependent viscosity of mMP could be obtained by mixing with glycerin. The viscosity and spreadability of mMP, which was three months after preparation, were 1992.0 ± 376.5 Pa·s and 2.1 ± 0.1 cm, respectively. In contrast, the viscosity and spreadability of MP mixed with glycerin were 436.9 ± 0.0 Pa·s and 2.8 ± 0.0 cm, respectively. The fixed invasion depth of MP was significantly higher than that of mMP (p < 0.05).
CONCLUSION
This study of a mixture of MP and Zn showed that the viscosity of mMP could be adjusted with glycerin. Also, the tissue fixation of mMP progressed slowly compared with that of MP. This finding suggests that mMP is effective and safe for Mohs treatment.
Topics: Humans; Mohs Surgery; Ointments; Rheology; Tissue Adhesives; Tissue Fixation; Zinc Oxide
PubMed: 29565714
DOI: 10.1089/jpm.2017.0585 -
International Journal of Dermatology Mar 2006The classical management of acne calls for prolonged oral and/or topical treatments; however, some patients request a rapid effect to make the papules disappear within a... (Clinical Trial)
Clinical Trial Randomized Controlled Trial
BACKGROUND
The classical management of acne calls for prolonged oral and/or topical treatments; however, some patients request a rapid effect to make the papules disappear within a few hours or days.
OBJECTIVE
To test the effect of a single overnight application of a paste containing 0.25% miconazole nitrate on acne papules, and comparison with the effect of the same but unmedicated paste.
METHOD
Narrow-band reflectance spectroscopy was used to assess the changes in E index (erythema) after overnight application of the pastes. In the first study, a total of 117 acne papules were assessed in 15 adolescents. Measurements of the E index were performed at 24-h intervals for 4 days on acne papules and the surrounding normal-looking skin. The last two assessments were performed the mornings preceding and following, respectively, a single application of the medicated paste. The second part of the study consisted of a double-blind, split-face study on 25 adolescents with acne. They applied each of the two formulations on a randomized part of the forehead. A total of 161 acne papules received the medicated paste and 160 received the same but unmedicated paste. Measurements were performed the mornings before and after the overnight treatment.
RESULTS
In the first part of the study, no significant daily difference was observed between the three series of pretreatment E indices, on both acne papules and normal skin. The treatment did not affect the E index of normal skin. By contrast, it decreased significantly the E index of the acne papules. The second part of the study also showed that the medicated paste significantly decreased the E index of acne papules. This effect was significantly (P < 0.05) superior to that of the unmedicated paste.
CONCLUSION
A single overnight application of miconazole nitrate paste appears to reduce the erythematous aspect of acne papules.
Topics: Acne Vulgaris; Administration, Topical; Adolescent; Anti-Infective Agents; Dermatologic Agents; Double-Blind Method; Drug Administration Schedule; Humans; Male; Miconazole; Ointments; Time Factors; Treatment Outcome; Zinc Oxide
PubMed: 16533239
DOI: 10.1111/j.1365-4632.2006.02685.x -
La Tribuna Odontologica Jul 1947
Topics: Dental Caries; Humans; Ointments
PubMed: 20272201
DOI: No ID Found -
Acta Biomaterialia Sep 2008Calcium phosphate (CaP) cements are being increasingly used for minimally invasive hard tissue implantation. Possible approaches to improve the bad injectability of...
Calcium phosphate (CaP) cements are being increasingly used for minimally invasive hard tissue implantation. Possible approaches to improve the bad injectability of hydraulic calcium phosphate pastes have been discussed and investigated in a number of recent publications. However, the liquid-phase separation mechanism leading to the limited injectability has not yet been addressed. Liquid-phase separation means that the liquid-to-powder ratio (LPR) of the extruded paste is higher than the LPR of the paste left in the syringe. The goal of this paper was to remedy this situation by looking at the liquid-phase migration occurring during the injection of a paste from a syringe through a cannula. Experimentally, it was seen that the liquid content of both the syringe paste and the extrudate decreased during the paste injection. Moreover, a high extrusion velocity, small syringe size, short cannula and high LPR favored a good injectability. These results could be partly explained in light of rheological measurements performed with the investigated paste.
Topics: Bone Cements; Calcium Phosphates; Cementation; Hardness; Injections; Ointments; Pressure; Viscosity
PubMed: 18445539
DOI: 10.1016/j.actbio.2008.03.004 -
Journal of Nanoscience and... Nov 2013Direct printing such as inkjet, gravure, and screen printing is an attractive approach for achieving low-cost circuitry in the printed circuit board industry. One of the...
Direct printing such as inkjet, gravure, and screen printing is an attractive approach for achieving low-cost circuitry in the printed circuit board industry. One of the challenges for direct printing technology, however, is the poor resistance to electrochemical migration (ECM), especially for silver (Ag) which has been widely used in printed electronics. We demonstrate improved resistance to Ag electrochemical migration by adding palladium (Pd) nanoparticles to the Ag nanopaste. Conductive comb-type patterns were fabricated on a bismaleimide-triazine substrate via screen printing. Their ECM characteristics were assessed by water drop test with deionized water. These results showed that the ECM time required for dendritic growth from cathode to anode to cause short-circuit failure was affected by the Pd content and applied voltages: the ECM time of Ag-15wt.% Pd nanopaste was nearly threefold that of Ag nanopaste, and the ECM time decreased by 94.22%, on average, while the applied voltage increased from 3 V to 9 V.
Topics: Crystallization; Electric Impedance; Macromolecular Substances; Materials Testing; Metal Nanoparticles; Molecular Conformation; Ointments; Palladium; Particle Size; Silver; Surface Properties
PubMed: 24245303
DOI: 10.1166/jnn.2013.7846