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Pediatrics in Review Nov 2021
Topics: Ductus Arteriosus, Patent; Humans; Infant, Newborn; Persistent Fetal Circulation Syndrome
PubMed: 34725225
DOI: 10.1542/pir.2020-004564 -
Cardiology Clinics Aug 2013Patent ductus arteriosus in adults is usually an isolated lesion with a small to moderate degree of shunt, as a larger shunt becomes symptomatic earlier in childhood.... (Review)
Review
Patent ductus arteriosus in adults is usually an isolated lesion with a small to moderate degree of shunt, as a larger shunt becomes symptomatic earlier in childhood. The classic murmur of patent ductus arteriosus may be the first clue to its presence, or it may be detected accidently by transthoracic echocardiography, computed tomography, or magnetic resonance angiography for an unrelated condition. The percutaneous approach is safe and effective in more than 98% of patients. Subacute bacterial endocarditis prophylaxis is not indicated routinely except for 6 months following the closure percutaneously or surgically.
Topics: Adult; Cardiac Catheterization; Cardiac Imaging Techniques; Ductus Arteriosus, Patent; Fetus; Humans; Long-Term Care; Physical Examination; Septal Occluder Device
PubMed: 23931103
DOI: 10.1016/j.ccl.2013.05.006 -
Scientific Reports May 2021To evaluate national epidemiologic data on infants treated for patent ductus arteriosus (PDA) in Korea and analyze outcomes associated with different PDA treatments. We...
To evaluate national epidemiologic data on infants treated for patent ductus arteriosus (PDA) in Korea and analyze outcomes associated with different PDA treatments. We retrospectively evaluated data on 12,336 patients diagnosed with PDA (International Classification of Diseases-10 code: Q250) between 2015 and 2018 from the Health Insurance Review and Assessment database. Among them, 1623 patients underwent surgical ligation (code: O1671). We used birth certificate data from Statistics Korea to estimate the prevalence, diagnosis, and treatment of PDA. The prevalence of infants with PDA was 81 infants per 10,000 live births and 45.2% in very low birth weight (VLBW) infants, which increased from 2015 to 2018. PDA ligation was performed in 2571 infants and 22% VLBW infants. Medical treatment was administered to 4202 infants, which decreased significantly, especially in VLBW infants (62% to 53%). The proportion of treatment was as follows: conservative treatment (53.1%), intravenous ibuprofen (24.4%), surgery (20.4%), and oral ibuprofen (10.7%); that among 4854 VLBW infants was as follows: intravenous ibuprofen (46.3%), conservative treatment (33.2%), surgery (22.2%), and oral ibuprofen (14.2%). Surgical treatment had a significantly higher risk (odds ratio 1.36) of mortality than conservative treatment. Surgical and/or medical treatments were associated with a higher risk of morbidity. Recently, increased use of conservative management of PDA has contributed to improved neonatal outcomes in VLBW infants. Select patients may still benefit from surgical ligation following careful consideration.
Topics: Clinical Decision-Making; Combined Modality Therapy; Disease Management; Ductus Arteriosus, Patent; Humans; Infant, Newborn; Odds Ratio; Outcome Assessment, Health Care; Prevalence
PubMed: 34021202
DOI: 10.1038/s41598-021-89868-z -
Circulation Oct 2006
Review
Topics: Abnormalities, Multiple; Adult; Aneurysm; Child; Diagnostic Techniques, Cardiovascular; Dinoprostone; Ductus Arteriosus; Ductus Arteriosus, Patent; Eisenmenger Complex; Epoprostenol; Heart Failure; Humans; Hypertension, Pulmonary; Incidence; Infant; Infant, Newborn; Oxygen
PubMed: 17060397
DOI: 10.1161/CIRCULATIONAHA.105.592063 -
Seminars in Veterinary Medicine and... Nov 1994
Review
Topics: Animals; Dog Diseases; Dogs; Ductus Arteriosus, Patent; Postoperative Care
PubMed: 7839025
DOI: No ID Found -
Congenital Heart Disease Sep 2018
Review
Topics: Cardiac Surgical Procedures; Conservative Treatment; Ductus Arteriosus, Patent; Hemodynamics; Humans; Infant, Newborn
PubMed: 30536607
DOI: 10.1111/chd.12689 -
World Journal of Pediatrics : WJP Apr 2022Acetaminophen use for pharmacological treatment of hemodynamically significant patent ductus arteriosus (hsPDA) in preterm infants is becoming more popular with emerging... (Review)
Review
BACKGROUND
Acetaminophen use for pharmacological treatment of hemodynamically significant patent ductus arteriosus (hsPDA) in preterm infants is becoming more popular with emerging evidence that it is effective as well as safe alternative for other agents used to close hsPDA.
DATA SOURCES
We performed a narrative review of literature about pharmacological treatment of PDA using acetaminophen.
RESULTS
Acetaminophen was used as a prophylaxis, symptomatic, targeted, and a rescue approach.
CONCLUSIONS
It appears that acetaminophen could be used in different approaches to close the hsPDA. Long-term outcomes of acetaminophen exposure early in life still lack certainty.
Topics: Acetaminophen; Ductus Arteriosus, Patent; Humans; Infant; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature
PubMed: 35253098
DOI: 10.1007/s12519-022-00526-4 -
Annals of Cardiac Anaesthesia 2021
Topics: Cardiomyopathy, Hypertrophic; Ductus Arteriosus, Patent; Humans
PubMed: 34747769
DOI: 10.4103/aca.ACA_53_20 -
Congenital Heart Disease Jan 2019Patent ductus arteriosus (PDA) is prevalent in premature newborns and has been linked to the development of bronchopulmonary dysplasia (BPD), a serious pulmonary... (Review)
Review
Patent ductus arteriosus (PDA) is prevalent in premature newborns and has been linked to the development of bronchopulmonary dysplasia (BPD), a serious pulmonary complication of premature birth. Although a causal relationship has not been proven, the link is greatest among infants born at lower gestational age who are treated with mechanical ventilation in the presence of a large ductal shunt. Despite strong association in epidemiological studies, treatment of a patent ductus arteriosus has not been shown to prevent BPD, and some therapies may increase the risk of BPD. We describe preclinical and clinical data demonstrating the association of a PDA with BPD, highlight the effects of surgical and pharmacological treatment, and explore the implications of recent clinical trials for the management of PDA in the premature newborn.
Topics: Bronchopulmonary Dysplasia; Ductus Arteriosus, Patent; Hemodynamics; Humans; Infant, Newborn; Infant, Premature
PubMed: 30343505
DOI: 10.1111/chd.12691 -
The Veterinary Record Jul 2016
Topics: Animals; Cat Diseases; Cats; Ductus Arteriosus, Patent; United Kingdom
PubMed: 27365241
DOI: 10.1136/vr.i3532