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Lancet (London, England) Jul 1973
Topics: Agranulocytosis; Anemia, Aplastic; Arthritis, Rheumatoid; Humans; Penicillamine
PubMed: 4124292
DOI: 10.1016/s0140-6736(73)93048-1 -
The Medical Letter on Drugs and... Aug 1978
Clinical Trial
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Humans; Penicillamine; Placebos
PubMed: 355819
DOI: No ID Found -
Lancet (London, England) Mar 1973
Topics: Arthritis, Rheumatoid; Humans; Penicillamine
PubMed: 4120661
DOI: 10.1016/s0140-6736(73)90743-5 -
Annals of the Rheumatic Diseases Dec 1976
Comparative Study
Topics: Adult; Aged; Arthritis, Rheumatoid; Drug Administration Schedule; Humans; Middle Aged; Penicillamine
PubMed: 1008625
DOI: 10.1136/ard.35.6.541-b -
Arthritis and Rheumatism Mar 1977Forty-four patients with definite or classic rheumatoid arthritis and failure to tolerate or respond to gold therapy were treated with D-penicillamine on a so-called...
Forty-four patients with definite or classic rheumatoid arthritis and failure to tolerate or respond to gold therapy were treated with D-penicillamine on a so-called go-slow, go-low regime. Seventeen patients tolerated the drug and had a 3-13 month follow-up assessment; 8 were markedly improved, 6 moderately or slightly improved, and 3 unimproved. Penicillamine had to be discontinued in 9 patients because of toxic side effects.
Topics: Aged; Arthritis, Rheumatoid; Drug Tolerance; Female; Humans; Male; Middle Aged; Penicillamine
PubMed: 849361
DOI: 10.1002/art.1780200205 -
Der Internist Jun 1974
Review
Topics: Adult; Agranulocytosis; Arthritis, Rheumatoid; Biodegradation, Environmental; Female; Humans; Kidney Diseases; Kinetics; Long-Term Care; Neurologic Manifestations; Penicillamine; Polyneuropathies; Skin Manifestations
PubMed: 4211090
DOI: No ID Found -
Investigative Ophthalmology & Visual... Oct 1987We studied the effect of two compounds, beta-aminopropionitrile (BAPN) and D-penicillamine on the success of experimental glaucoma filtering surgery in cynomolgus...
We studied the effect of two compounds, beta-aminopropionitrile (BAPN) and D-penicillamine on the success of experimental glaucoma filtering surgery in cynomolgus monkeys. All animals had laser-induced glaucoma and underwent punch sclerectomy operations. Eyes treated with BAPN or D-penicillamine maintained successful filtration for at least 3 days longer than nondrug-treated controls. This effect, while statistically significant (P less than 0.05), was temporary. The lack of more substantial improvement in prolonging filtering patency may have resulted from an inadequate effective drug concentration. Alternatively, these drugs may have limited potency because their action on new collagen synthesis affects only a minor component of the healing process that causes filter failure.
Topics: Aminopropionitrile; Animals; Female; Glaucoma; Macaca fascicularis; Male; Penicillamine; Postoperative Complications; Postoperative Period; Sclera
PubMed: 3654136
DOI: No ID Found -
Terapevticheskii Arkhiv 1977
Review
Topics: Collagen Diseases; Dose-Response Relationship, Drug; Drug Eruptions; Drug Evaluation; Drug Hypersensitivity; Dyspepsia; Hematologic Diseases; Humans; Kidney Diseases; Myasthenia Gravis; Penicillamine
PubMed: 145661
DOI: No ID Found -
Nederlands Tijdschrift Voor Geneeskunde Mar 1976
Topics: Arthritis, Rheumatoid; Humans; Penicillamine
PubMed: 1250435
DOI: No ID Found -
La Presse Medicale Oct 1966
Topics: Humans; Lead Poisoning; Penicillamine
PubMed: 5922817
DOI: No ID Found