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Southern Medical Journal Mar 1985An 18-year-old man had an eventually fatal case of Peptococcus magnus endocarditis. Multiple emboli and continued valve destruction occurred during appropriate therapy....
An 18-year-old man had an eventually fatal case of Peptococcus magnus endocarditis. Multiple emboli and continued valve destruction occurred during appropriate therapy. Penicillin therapy was associated with fever and neutropenia, thought to be due to an immunologic mechanism.
Topics: Adolescent; Endocarditis, Bacterial; Humans; Male; Peptococcus
PubMed: 3975758
DOI: 10.1097/00007611-198503000-00035 -
Nihon Saikingaku Zasshi. Japanese... Mar 1987
Review
Topics: Cytosine; DNA, Bacterial; Fatty Acids; Guanine; Peptococcus; Peptostreptococcus
PubMed: 3302346
DOI: 10.3412/jsb.42.471 -
Annals of Internal Medicine Aug 1980Peptococcus magnus was recovered from 10% of anaerobic cultures collected from suspected clinical infections over a 3.5-year period. It was the commonest species of...
Peptococcus magnus was recovered from 10% of anaerobic cultures collected from suspected clinical infections over a 3.5-year period. It was the commonest species of anaerobic gram-positive cocci isolated (30%). To evaluate the clinical significance of this organism, we retrospectively reviewed the charts of 222 patients from whom P. magnus was isolated. Twenty-five patients had no evidence of infection, 151 had mixed infections, and 32 had infections from which only P. magnus was isolated (pure cultures). Mixed infections involved the following sites: bone and joint (32 cases), soft tissue (57 cases), foot ulcers (29 cases), abdominal cavity (16 cases), and miscellaneous (17 cases). The average number of organisms was four (2.5 facultatives and 1.5 anaerobes). Eighteen patients with pure cultures of P. magnus had bone or joint infections, and foreign bodies were present in 15 of these. Other pure cultures of P magnus infections included 12 soft tissue, one vascular graft, and one infected sternotomy with persistent bacteremia. Pure culture infections were usually chronic, and serious sequelae often resulted. Peptococcus magnus is frequently isolated from significant infections and seems particularly pathogenic in infections of bones and joints or in association with the presence of foreign bodies, or both.
Topics: Adult; Aged; Arthritis, Infectious; Bacterial Infections; Bone Diseases; Female; Foot Diseases; Humans; Joint Diseases; Male; Middle Aged; Peptococcus; Skin Diseases, Infectious
PubMed: 7406374
DOI: 10.7326/0003-4819-93-2-244 -
Archives of Plastic Surgery Nov 2012
PubMed: 23233897
DOI: 10.5999/aps.2012.39.6.669 -
Indian Pediatrics Sep 1988
Topics: Child; Endocarditis, Bacterial; Humans; Male; Peptococcus; Rheumatic Fever
PubMed: 3243640
DOI: No ID Found -
Journal of Cancer 2024Regulating the immune system is a crucial measure of gut microbiota (GM) that influences the development of diseases. The causal role of GM on Non-small cell lung...
Regulating the immune system is a crucial measure of gut microbiota (GM) that influences the development of diseases. The causal role of GM on Non-small cell lung cancer (NSCLC) and whether it can be mediated by immune cells is still unknown. We performed a two-step, two-sample Mendelian randomization study with an Inverse variance weighted (IVW) approach to investigate the causal role of GM on NSCLC and the mediation effect of immune cells between the association of GM and NSCLC. MR analyses determined the protective effects of 6 genera on NSCLC (Bacteroides, Roseburia, Alistipes, Methanobrevibacter, Ruminococcus gauvreauii group, and Peptococcus). In addition, 38 immune cell traits were suggestively associated with NSCLC. Of note, the mediation MR illustrated the causal role of Genus-Peptococcus on NSCLC (Total effect IVW: OR = 0.790, 95% CI [0.657, 0.950], P = 0.012) was to a large proportion mediated by CD45 on HLA DR CD4 in TBNK panel (-034 (95% CI [-0.070, -0.005]; P = 0.037), accounting for 14.4% of Total effect). The study suggested a causal relationship between GM and NSCLC, which may be mediated by immune cells.
PubMed: 38434967
DOI: 10.7150/jca.92699 -
Journal of General Microbiology May 1976Several strains of a new, obligately anaerobic, Gram-positive coccus were isolated from sheep rumen contents. An important distinctive feature was their reductive...
Several strains of a new, obligately anaerobic, Gram-positive coccus were isolated from sheep rumen contents. An important distinctive feature was their reductive cleavage of hepatotoxic pyrrolizidines, using hydrogen gas or formate as hydrogen donor. With the same hydrogen donors, the organism reduced nitrate and fumarate. In all cases, the reductive metabolism formed part of an energy-giving sequence used by the organism for growth. This new coccus also utilized energy obtained by dissimilation of arginine. Enzymic hydrolysates of casein and yeast autolysate were satisfactory substrates for growth but no strain fermented carbohydrates. Ultrasonic extracts of the coccus contained a c-type cytochrome. The characteristics of the organism are consistent with its allocation to the genus Peptococcus within which it differs significantly from currently recognized species. The name Peptococcus heliotrinreducans is proposed for this new species, and a reliable method for isolating it is described.
Topics: Anaerobiosis; Animals; Cytochromes; Fumarates; Nitrates; Peptococcaceae; Peptococcus; Pyrrolizidine Alkaloids; Rumen; Sheep; Terminology as Topic
PubMed: 945326
DOI: 10.1099/00221287-94-1-1 -
Iranian Journal of Microbiology Apr 2016Brain abscess remains a potentially fatal central nervous system (CNS) disease, especially in developing countries. Anaerobic abscess is difficult to diagnose because of...
BACKGROUND AND OBJECTIVES
Brain abscess remains a potentially fatal central nervous system (CNS) disease, especially in developing countries. Anaerobic abscess is difficult to diagnose because of cumbersome procedures associated with the isolation of anaerobes.
MATERIALS AND METHODS
This is a hospital-based retrospective microbiological analysis of 430 brain abscess materials (purulent aspirates and/or tissue), for anaerobic organisms, that were received between 1987-2014, by the Microbiology Laboratory in our Institute.
RESULTS
Culture showed growth of bacteria 116/430 (27%) of the cases of which anaerobes were isolated in 48/116 (41.1%) of the cases. Peptostreptococcus (51.4 %), was the predominant organism isolated in four cases followed by Bacteroides and Peptococcus species.
CONCLUSION
Early diagnosis and detection of these organisms would help in the appropriate management of these patients.
PubMed: 27307977
DOI: No ID Found -
Acta Veterinaria Scandinavica 1975On the basis of biochemical and serological criteria 2 hemolysin forming varieties of peptococci were identified as Peptococcus indolicus. Of a total of 16 hemolytic...
On the basis of biochemical and serological criteria 2 hemolysin forming varieties of peptococci were identified as Peptococcus indolicus. Of a total of 16 hemolytic strains examined 9 originated from the vagina of clinically healthy cows, 4 from mastitis secretions from dry cows, 2 from the interdigital skin of clinically healthy sows, and 1 from a subcutaneous abscess in a pig. Two strains were designated a-hemolytic and 14 β-hemolytic. On blood agar plates colonies of the α-hemolytic variety were surrounded by narrow zones of almost complete hemolysis, while colonies of the β-hemolytic variety were surrounded by broad zones of incomplete hemolysis. The hemolysins were termed α- and β-hemolysin, respectively. The β-hemolysin, but not the α-hemolysin, could be demonstrated in cultures grown in liquid media. The β-hemolysin was found to be filtrable, relatively thermoresistant, and non-dermonecrotic. By gel diffusion analyses the 2 α-hemolytic strains were referred to Serotype C. Ten of the β-hemolytic strains belonged to Serotype C, 2 to Type B, 1 to Type D, and 1 to Type E.
Topics: Animals; Cattle; Female; Guinea Pigs; Hemolysin Proteins; Mastitis, Bovine; Mice; Peptococcus; Rabbits; Swine; Vagina
PubMed: 1180185
DOI: 10.1186/BF03546676 -
International Journal of Systematic and... Dec 2016A study of the faecal microbiome in three healthy female rhesus macaques revealed the presence of a novel obligately anaerobic, chemoorganoheterotrophic, non-sporing,...
A study of the faecal microbiome in three healthy female rhesus macaques revealed the presence of a novel obligately anaerobic, chemoorganoheterotrophic, non-sporing, coccoid, non-motile, Gram-stain-positive bacterial species. Three strains of this species, designated as M108T, M916-1/1, and M919-2/1, were non-haemolytic, H2S-positive, catalase-positive, bile- and NaCl-sensitive and required peptone for growth. Strains also were asaccharolytic, able to utilize sulfite, thiosulfate and elemental sulfur as electron acceptors, and produced acetic and butyric acids as metabolic end-products. Strain M108T is characterized by the prevalence of C14 : 0, C16 : 0 and C18 : 1ω9cis dimethyl acetal among the cellular fatty acids, and the presence of MK-10 menaquinone. The DNA G+C content was found to be 51 mol%. Phylogenetic analysis of partial 16S rRNA gene sequences of strains M108T, M916-1/1 and M919-2/1 placed these strains into the genus Peptococcus (family Peptococcaceae). On the basis of phenotypic and genotypic properties we conclude that these strains represent a novel bacterial species for which the name Peptococcus simiae sp. nov. is proposed. The type strain is M108T (=DSM 100347T=VKM B-2932T).
Topics: Animals; Bacterial Typing Techniques; Base Composition; DNA, Bacterial; Fatty Acids; Feces; Female; Macaca mulatta; Peptococcus; Phylogeny; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Ubiquinone
PubMed: 27613234
DOI: 10.1099/ijsem.0.001494