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La Tunisie Medicale Nov 1999The cases of vasculitis associated to malignant tumour are uncommon, their course which is often parallel suggests a direct link between them. We report the observation...
The cases of vasculitis associated to malignant tumour are uncommon, their course which is often parallel suggests a direct link between them. We report the observation of periarteritis nodosa associated with a lung cancer discovered in the following of vasculitis; whereas the course is favorable in 83 years old man without particular history. The frequency of neoplasia with vasculitis is estimated between 3 and 8%, and periarteritis nodosa can't be a paraneoplastic syndrome. Lung and colic tumours are the most frequent reported of the solid tumours. The delay of appearance of vasculitis varies from 25 months before to 9 months after cancer diagnosis. There are many factors, either some treatment, the neoantigens involve the formation of immune complexes, lymphokines and some vasoactive substances.
Topics: Aged; Aged, 80 and over; Antigen-Antibody Complex; Diagnosis, Differential; Humans; Lung Neoplasms; Male; Polyarteritis Nodosa
PubMed: 10730147
DOI: No ID Found -
Acta Medica Scandinavica Jun 1972
Topics: Adult; Electrophoresis, Paper; Female; Follow-Up Studies; Humans; Male; Middle Aged; Polyarteritis Nodosa; Prognosis
PubMed: 4402601
DOI: No ID Found -
The American Journal of Pathology Mar 1978In 7 unselected necropsy cases of clinically diagnosed periarteritis nodosa, the detection of hepatitis B surface antigen (HBsAg) and hepatitis B core antigen (HBcAg) in...
In 7 unselected necropsy cases of clinically diagnosed periarteritis nodosa, the detection of hepatitis B surface antigen (HBsAg) and hepatitis B core antigen (HBcAg) in the cytoplasm and nuclei of hepatocytes indicated an ongoing infection with hepititis B virus (HBV). In all these cases histologic changes found in the liver varied from "minimal" to chronic aggressive hepatitis. In all the cases, deposits of HBsAg, immunoglobulins, beta1C-globulin and C1q were detected in vascular lesions. That these deposits could represent HBsAg-anti-HBs immune complexes was supported by demonstrating their strong binding of guinea pig complement and by the successful elution of all HBsAg and part of the immunoglobulin from these deposits by treatment with buffers known to dissociate antigen-antibody bonds but not with phosphate-buffered saline, pH 7.6 (PBS). Glomerulonephritis associated with these immune complexes was found in 6 cases. The presence of larger masses of HBsAg immune complexes, chiefly in recent insudative and fibrinoid vascular lesions, their lesser amounts in lesions undergoing involution, and their absence from healed lesions strongly suggest that these complexes play a primary role in the pathogenesis of acute vascular damage in periarteritis nodosa.
Topics: Adult; Antigen-Antibody Complex; Complement C1; Female; Glomerulonephritis; Hepatitis B Surface Antigens; Humans; Immunoglobulins; Liver; Male; Middle Aged; Polyarteritis Nodosa
PubMed: 24342
DOI: No ID Found -
Arthritis and Rheumatism Apr 1997
Topics: Adult; Arteritis; Diagnosis, Differential; Female; Glomerulonephritis; Humans; Male; Middle Aged; Polyarteritis Nodosa
PubMed: 9125267
DOI: 10.1002/art.1780400431 -
Pathologia Et Microbiologia 1975
Topics: Animals; Arteries; Child; Child, Preschool; Female; Humans; Infant; Japan; Lymph Nodes; Male; Mice; Myocardium; Polyarteritis Nodosa; Syndrome; Thymus Gland
PubMed: 6935
DOI: 10.1159/000162822 -
The Surgical Clinics of North America Aug 1952
Topics: Biopsy; Humans; Polyarteritis Nodosa
PubMed: 14950699
DOI: No ID Found -
Annals of the Rheumatic Diseases Dec 1954
Topics: Arthritis; Arthritis, Rheumatoid; Humans; Polyarteritis Nodosa
PubMed: 13229234
DOI: 10.1136/ard.13.4.277 -
British Medical Journal Oct 1954
Topics: Abscess; Humans; Infarction; Liver; Liver Abscess; Liver Diseases; Polyarteritis Nodosa; Vascular Diseases
PubMed: 13199312
DOI: 10.1136/bmj.2.4891.794 -
La Revue de Medecine Interne Dec 1999Polyarteritis nodosa is a disease process with a wide clinical spectrum, ranging from a severe generalized multisystem disorder to a more benign condition which may...
INTRODUCTION
Polyarteritis nodosa is a disease process with a wide clinical spectrum, ranging from a severe generalized multisystem disorder to a more benign condition which may remain limited to the skin, muscles and peripheral nerves, and is termed cutaneous polyarteritis nodosa. Periosteal bone formation is uncommon in this condition.
EXEGESIS
We report two cases (two female patients of 80 and 55 years of age, respectively) who complained of red, tender nodules of legs and bone pain. Histological changes were those of necrotizing arteritis of the small and medium arteries in the panniculus and dermis. Bone X-ray showed periosteal bone formation.
CONCLUSION
In patients with pain, skin changes and swelling of the lower limbs, the diagnosis of periarteritis nodosa with periostitis has to be considered.
Topics: Aged; Aged, 80 and over; Bone Development; Diagnosis, Differential; Female; Humans; Leg; Middle Aged; Pain; Polyarteritis Nodosa
PubMed: 10635076
DOI: 10.1016/s0248-8663(00)87528-1 -
Praxis Oct 2003Polyarteritis nodosa is a vasculitis of unknown origin which can be rarely associated with hepatitis B. A exceptional clinical situation of a polyarteritis nodosa... (Comparative Study)
Comparative Study
Polyarteritis nodosa is a vasculitis of unknown origin which can be rarely associated with hepatitis B. A exceptional clinical situation of a polyarteritis nodosa associated with hepatitis C is described. This case is also the occasion to review the clinical manifestations, the diagnostic strategy und the therapeutic options of this rare vasculitis.
Topics: Adult; Biopsy; Diagnosis, Differential; Electromyography; Female; Hepatitis C; Humans; Polyarteritis Nodosa
PubMed: 14587365
DOI: 10.1024/0369-8394.92.41.1717