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The Journal of Family Practice Nov 2015Finding the optimal method of birth control for women in their 40s requires careful attention to medical history, risk factors, and perimenopausal symptoms, as well as...
Finding the optimal method of birth control for women in their 40s requires careful attention to medical history, risk factors, and perimenopausal symptoms, as well as the risk of unintended pregnancy.
Topics: Contraception; Female; Humans; Middle Aged; Perimenopause; Pregnancy; Risk Factors
PubMed: 26697541
DOI: No ID Found -
Zhongguo Zhen Jiu = Chinese Acupuncture... Mar 2010The literatures are retrieved in the Chinese science and technology periodical database of VIP (1989-2009). The clinical application and its mechanism of perimenopausal... (Review)
Review
The literatures are retrieved in the Chinese science and technology periodical database of VIP (1989-2009). The clinical application and its mechanism of perimenopausal syndrome treated with acupuncture and moxibustion are summarized. The summarized literatures indicate that body acupuncture, auricular acupuncture, acupoint catgut embedding and combined therapy are used in acupuncture and moxibustion for treatment of perimeno-pausal syndrome. The research of mechanism includes regulation of nerve-endocrine-immunity net, regulation of free radical metabolism, regulation of blood lipid and bone metabolism. The literatures suggest that acupuncture and moxibustion has definite therapeutic effect on perimenopausal syndrome with advantages of convenience, lower cost and safety.
Topics: Acupuncture Therapy; Bone and Bones; Female; Humans; Lipid Metabolism; Moxibustion; Perimenopause
PubMed: 20496744
DOI: No ID Found -
Menopause (New York, N.Y.) Feb 2023To investigate the utilization of complementary and alternative medicine (CAM) by perimenopausal women and explore factors associated with their preference.
OBJECTIVE
To investigate the utilization of complementary and alternative medicine (CAM) by perimenopausal women and explore factors associated with their preference.
METHODS
A cross-sectional study was conducted involving 558 perimenopausal women in Wuhan, China. Online questionnaires were available from December 2021 to April 2022. Instruments used were the International Complementary and Alternative Medicine Questionnaire and the Greene Climacteric Scale. The association between scores and participants' sociodemographic characteristics and perimenopausal symptoms was analyzed using multiple linear regression.
RESULTS
The overall utilization of CAM by perimenopausal women was 50.4% (281/558). Perimenopausal symptoms affecting the frequency of CAM usage included anxiety (adjusted β = 0.18), somatic (adjusted β = 0.07), and vasomotor symptoms (adjusted β = 0.76), P < 0.05. The most commonly used CAM were massage (37.7%), herbal therapies (19.9%), and dietary supplements (18.2%). Walking (58.6%) was the most popular self-practice therapy. Perimenopausal women consulted Western (38.4%) and Chinese medicine physicians (34.8%) and dentists (36.0%) most frequently.
CONCLUSIONS
Perimenopausal women experience discomforts during this age-related stage, and their use of CAM to manage symptoms is common. The usage and preferences of these management strategies are worthy of further exploration. There is a need to understand cost-effective and appropriate management interventions to improve the quality of life of perimenopausal women.
Topics: Humans; Female; Perimenopause; Cross-Sectional Studies; Quality of Life; Complementary Therapies; Surveys and Questionnaires; China
PubMed: 36696646
DOI: 10.1097/GME.0000000000002124 -
Nursing ResearchMidlife perimenopausal and postmenopausal women with metabolic syndrome experience multiple symptoms concurrently.
BACKGROUND
Midlife perimenopausal and postmenopausal women with metabolic syndrome experience multiple symptoms concurrently.
OBJECTIVE
The study objectives were to examine the relationship among symptoms through network visualization and identify and compare symptom clusters and key symptoms across symptom occurrence and symptom severity dimensions in midlife perimenopausal and postmenopausal women with and without metabolic syndrome.
METHODS
Cross-sectional data from the Study of Women's Health Across the Nation (Visit 5) were used for analysis. A machine-learning-based network analysis and the Walktrap algorithm were used to fulfill the study objectives.
RESULTS
The number and types of symptom clusters differed between the groups. Midlife perimenopausal and postmenopausal women with metabolic syndrome experienced the psychological/somatic/genital cluster (key symptom: frequent mood change), the sleep/urinary cluster (sleep disturbance), and the vasomotor cluster (cold sweat) in the symptom occurrence dimension and the psychological/somatic/sexual cluster (anxiety), the sleep/urinary cluster (sleep disturbance), and the vasomotor/genital cluster (night sweat) in the symptom severity dimension. In contrast, midlife perimenopausal and postmenopausal women without metabolic syndrome experienced the psychological cluster (anxiety), the sleep/somatic/genitourinary cluster (sleep disturbance), and the vasomotor cluster (night sweat) in the symptom occurrence dimension and the psychological/somatic cluster (anxiety), the sleep/urinary cluster (sleep disturbance), the vasomotor cluster (night sweat), and the sexual/genital cluster (vaginal dryness) in the symptom severity dimension.
DISCUSSION
The study findings may serve as a knowledge basis for effective assessment and management of symptom clusters and key symptoms in clinical settings and provide directions for future development of targeted symptom management interventions.
Topics: Cross-Sectional Studies; Female; Hot Flashes; Humans; Metabolic Syndrome; Perimenopause; Postmenopause; Sleep Wake Disorders
PubMed: 35759720
DOI: 10.1097/NNR.0000000000000591 -
Taiwanese Journal of Obstetrics &... Jul 2021Fatigue, a painful and unpleasant subjective experience, is common in perimenopausal women. Therefore, an effective tool to evaluate the fatigue-precipitating factor is...
OBJECTIVE
Fatigue, a painful and unpleasant subjective experience, is common in perimenopausal women. Therefore, an effective tool to evaluate the fatigue-precipitating factor is important for perimenopausal women prone to fatigue syndrome.
MATERIALS AND METHODS
This study was surveyed by short-term perimenopausal fatigue scale. The enrollment period was from November 2019 to January 2020. The subjects were perimenopausal women prone to perimenopausal fatigue. The differences between the fatigue-precipitating factors and the degrees of fatigue and disturbance were determined by one-way ANOVA and t test.
RESULTS
A total of 220 perimenopausal women with mean age of 51.3 years were included. Among these, 64.1% did not have a habit of regular exercise and 55.5% had chronic diseases. Fatigue syndrome was found in 64.1% of subjects, who were mainly presented by shoulder and neck pain and sleep problems. There were significant differences between "perimenopausal fatigue" and "duration" (p < 0.001); "with and without regular exercise" (p = 0.05); and "with and without chronic diseases" (p = 0.03).
CONCLUSIONS
Our study showed the perimenopausal fatigue syndrome is more frequently found in perimenopausal women who have a co-morbidity (chronic illness) and do not have a habit of regular exercise. An early identification and prompt intervention may help perimenopausal women to deal with their fatigue syndrome. The short questionnaire perimenopausal fatigue scale seems to be useful for screening perimenopausal women prone to fatigue syndrome.
Topics: Analysis of Variance; Chronic Disease; Diagnostic Self Evaluation; Exercise; Factor Analysis, Statistical; Fatigue; Female; Humans; Middle Aged; Perimenopause; Qualitative Research; Reproducibility of Results; Surveys and Questionnaires; Syndrome; Taiwan
PubMed: 34247816
DOI: 10.1016/j.tjog.2021.05.026 -
Obstetrics and Gynecology Clinics of... Sep 2011The impact of perimenopause on cognition seems to be characterized by an absence of improved scores rather than a decline. In the SWAN, the perimenopausal decrement in... (Review)
Review
The impact of perimenopause on cognition seems to be characterized by an absence of improved scores rather than a decline. In the SWAN, the perimenopausal decrement in cognitive performance was not accounted for; however, increases in anxiety and depressive symptoms had independent, unfavorable effects on performance. Estradiol has been found to protect against changes resulting from serotonin withdrawal and defend against changes from cholinergic depletion. There is support for the critical timing hypothesis--that estrogen benefits cognitive function when instituted early, but not later. The menopausal transition may affect cognitive function in older age owing to worsened cardiovascular risk factors.
Topics: Age Factors; Animals; Brain; Cardiovascular Diseases; Cognition Disorders; Estrogens; Female; Gonadal Steroid Hormones; Humans; Hydrocortisone; Models, Animal; Ovariectomy; Perimenopause; Primary Ovarian Insufficiency
PubMed: 21961718
DOI: 10.1016/j.ogc.2011.05.007 -
JAAPA : Official Journal of the... Jan 2013
Topics: Estrogen Replacement Therapy; Female; Humans; Perimenopause; Quality of Life; Severity of Illness Index; Sleep Initiation and Maintenance Disorders; Sleep Wake Disorders
PubMed: 23356003
DOI: 10.1097/01720610-201301000-00011 -
BMC Women's Health Jan 2021There is a noticeable lack of systematic researches on evaluating the correlation between serum estrogen levels and changes in brain functional areas of perimenopausal...
BACKGROUND
There is a noticeable lack of systematic researches on evaluating the correlation between serum estrogen levels and changes in brain functional areas of perimenopausal women.The aim of this study is to investigate the regional spontaneous brain activity changes in perimenopausal women.
METHODS
Based on the resting-state functional magnetic resonance imaging datasets acquired from 25 perimenopausal women and 20 healthy women of reproductive age, a two-sample t-test was performed on individual normalized regional homogeneity (ReHo) maps. Relationships between abnormal ReHo values and the self-rating anxiety scale (SAS), the self-rating depression scale (SDS) were investigated with Pearson correlation analysis. We also investigated the correlation between abnormal ReHo values and serum estrogen level.
RESULTS
In the perimenopausal group, we found increased ReHo in the right posterior cerebellum (region 2), left middle frontal gyrus and left middle cingulate gyrus ([Formula: see text]). Additionally, the ReHo values in left middle frontal gyrus and leftt middle cingulate gyrus showed positively significant correlation with the SAS, SDS scores. On the contrary, there was no significant correlation between the ReHo value in right posterior cerebellum and SDS, SAS scores. In the perimenopausal group, the ReHo values in the left middle frontal gyrus and left middle cingulate gyrus were negatively correlated with the serum estrogen level ([Formula: see text]).
CONCLUSION
The results of this preliminary study have suggested that abnormal spontaneous activities of multiple brain regions during resting state was already altered in perimenopausal women. Alterative activities might be related to emotional regulation deficits and cognitive impairment, and might potentially represent the neural mechanism underlying perimenopausal period.
Topics: Brain; Female; Humans; Magnetic Resonance Imaging; Perimenopause
PubMed: 33509177
DOI: 10.1186/s12905-020-01171-7 -
JAMA Psychiatry May 2018
Topics: Depression; Estradiol; Female; Humans; Menopause; Perimenopause; Progesterone
PubMed: 29617513
DOI: 10.1001/jamapsychiatry.2018.0615 -
JAMA Psychiatry May 2018
Topics: Depression; Estradiol; Female; Humans; Menopause; Perimenopause; Progesterone
PubMed: 29617516
DOI: 10.1001/jamapsychiatry.2018.0368