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The Canadian Journal of Neurological... Jan 2018
Topics: Epilepsy; Female; Humans; Purpura; Young Adult
PubMed: 28978365
DOI: 10.1017/cjn.2017.235 -
Emergency Medicine Journal : EMJ Apr 2013
Topics: Accidents, Traffic; Asphyxia; Child, Preschool; Facial Dermatoses; Humans; Male; Purpura
PubMed: 22983981
DOI: 10.1136/emermed-2012-201815 -
Presse Medicale (Paris, France : 1983) Oct 2012Recreational or regular physical and sport activities may be responsible for a wide range of cutaneous complications. Among them, "sports purpura" is a peculiar symptom... (Review)
Review
Recreational or regular physical and sport activities may be responsible for a wide range of cutaneous complications. Among them, "sports purpura" is a peculiar symptom that can occur during a large number of sports. "Effort purpura" defines any purpura occurring within the context of physical exercise irrespective of its cause. Therefore this clinical diagnosis includes various aetiologies. Diagnosis of traumatic purpura is often easy if the sport is mentioned in the anamnesis; cutaneous exercise - induced vasculitis must be also noted. Purpura can reveal systemic diseases or internal haemorrhage, such as spleen rupture, thrombopathies or systemic vasculitis, and other effort purpuras must be taken into account, including those related to the environment (cold, sun exposure...). Knowledge of a physical activity before the occurrence of purpura should be known by practitioner to avoid unnecessary and costly explorations in most of the cases.
Topics: Athletes; Athletic Injuries; Humans; Physical Exertion; Purpura; Sports; Vasculitis
PubMed: 22386284
DOI: 10.1016/j.lpm.2012.01.031 -
Cold Spring Harbor Molecular Case... Feb 2022Ethylmalonic encephalopathy (MIM #602473) is a rare autosomal recessive metabolic condition caused by biallelic variants in (MIM #608451), characterized by global...
Ethylmalonic encephalopathy (MIM #602473) is a rare autosomal recessive metabolic condition caused by biallelic variants in (MIM #608451), characterized by global developmental delay, infantile hypotonia, seizures, and microvascular damage. The microvascular changes result in a pattern of relapsing spontaneous diffuse petechiae and purpura, positional acrocyanosis, and pedal edema, hemorrhagic suffusions of mucous membranes, and chronic diarrhea. Here, we describe an instructive case in which ethylmalonic encephalopathy masqueraded as meningococcal septicemia and shock. Ultrarapid whole-genome testing (time to result 60 h) and prompt biochemical analysis facilitated accurate diagnosis and counseling with rapid implementation of precision treatment for the metabolic crisis related to this condition. This case provides a timely reminder to consider rare genetic diagnoses when atypical features of more common conditions are present, with an early referral to ensure prompt biochemical and genomic diagnosis.
Topics: Brain Diseases, Metabolic, Inborn; Humans; Mitochondrial Proteins; Nucleocytoplasmic Transport Proteins; Purpura; Sepsis
PubMed: 35165146
DOI: 10.1101/mcs.a006193 -
The Medical Clinics of North America Jan 1972
Topics: Adrenal Cortex Hormones; Adult; Anaphylaxis; Blood Pressure; Blood Vessels; Child; Edema; Gastrointestinal Hemorrhage; Humans; Kidney; Kidney Function Tests; Purpura; Skin; Skin Manifestations
PubMed: 4536635
DOI: 10.1016/s0025-7125(16)32435-x -
Archives of Dermatology Jun 1992Purpuric eruptions due to local mechanical causes are commonly seen, particularly in children. These eruptions are not always recognized as isolated purpura, and the...
BACKGROUND
Purpuric eruptions due to local mechanical causes are commonly seen, particularly in children. These eruptions are not always recognized as isolated purpura, and the patient may be submitted to an unnecessary extensive hematologic workup. We present various causes of suction purpura and outline a logical investigational approach.
OBSERVATIONS
Suction purpura result from an external force exerting negative pressure on a circumscribed area of the skin, producing small grouped petechiae. We present a number of such suction purpura-causing mechanisms: Pressure during the delivery of a neonate, children's habits or play activities, and iatrogenic causes produce similar cutaneous lesions. We also describe the gas mask suction purpura for the first time.
CONCLUSIONS
Once the causative factor is established, there is no need for further investigation or treatment of suction purpura. The lesions will fade completely within a few days.
Topics: Adolescent; Adolescent Behavior; Adult; Child; Humans; Infant, Newborn; Play and Playthings; Purpura; Respiratory Protective Devices; Self-Injurious Behavior; Sexual Behavior; Suction; Vacuum Extraction, Obstetrical
PubMed: 1599272
DOI: No ID Found -
Pathologica Dec 1994Bateman's disease is characterized by the presence of purpuric eruptions involving the extremities. Semi-thin sections and morphological pictures evidence the damage...
Bateman's disease is characterized by the presence of purpuric eruptions involving the extremities. Semi-thin sections and morphological pictures evidence the damage this illness can cause to the elastic fibres. After passing in review the various pathogenetic theories, the Authors consider this disease an expression of discrasic alterations of an amyloidosic character of all the vessel structures, of severe senile elastosis and of the lack of fibrin-like material.
Topics: Humans; Purpura
PubMed: 7617395
DOI: No ID Found -
Nederlands Tijdschrift Voor Geneeskunde May 2018The Waterhouse-Friderichsen syndrome (WFS) is a serious illness associated with a high mortality rate and characterized by septic shock and signs of adrenocortical...
BACKGROUND
The Waterhouse-Friderichsen syndrome (WFS) is a serious illness associated with a high mortality rate and characterized by septic shock and signs of adrenocortical insufficiency.
CASE DESCRIPTION
A 33-year-old male was seen in the emergency department with severe abdominal and back pain with diffuse mottled skin and rapidly progressive petechiae all over his body. Laboratory results showed severe lactate acidosis with renal dysfunction and indications of diffuse intravascular coagulation. Because he had signs of progressive septic shock, the patient was admitted to the ICU. There he subsequently developed hypoglycaemia (glucose < 0.1 mmol/l) and CPR had to be performed twice - the patient died shortly afterwards. Autopsy showed bilateral necrosis and haemorrhage of the adrenal glands, indicative of the diagnosis of WFS. Streptococcus pneumoniae was identified.
CONCLUSION
In case of sepsis, with fever, rapidly expanding petechiae and purpura the Waterhouse-Friderichsen syndrome should be considered. Intensive therapy with antibiotics, fluids, vasopressors, and corticosteroids should be initiated immediately.
Topics: Adult; Fatal Outcome; Humans; Male; Pneumococcal Infections; Purpura; Shock, Septic; Streptococcus pneumoniae; Waterhouse-Friderichsen Syndrome
PubMed: 30040272
DOI: No ID Found -
Transfusion Aug 2019
Review
Topics: Aged; Erythrocyte Transfusion; Female; Humans; Purpura; Skin Diseases, Vascular; Transfusion Reaction
PubMed: 31175667
DOI: 10.1111/trf.15392 -
Cutis May 2022
Topics: Humans; Leg; Levamisole; Purpura
PubMed: 35856753
DOI: 10.12788/cutis.0524