-
BMJ (Clinical Research Ed.) Jun 2023
Topics: Humans; Leg; Purpura; Lower Extremity; Exanthema
PubMed: 37348904
DOI: 10.1136/bmj-2023-075249.r1 -
Seminars in Thrombosis and Hemostasis Jul 1984
Review
Topics: Adult; Aged; Blood Coagulation Disorders; Blood Platelet Disorders; Embolism; Endothelium; Female; Humans; IgA Vasculitis; Male; Microcirculation; Middle Aged; Purpura; Thrombocytopenia
PubMed: 6382614
DOI: 10.1055/s-2007-1004421 -
Cleveland Clinic Journal of Medicine Jan 2024
Topics: Humans; Endocarditis, Bacterial; Endocarditis; Purpura
PubMed: 38167396
DOI: 10.3949/ccjm.91a.23041 -
Journal of Cosmetic Dermatology Dec 2019
Topics: Drug Therapy, Combination; Humans; Purpura
PubMed: 30809925
DOI: 10.1111/jocd.12880 -
Clinics in Dermatology 2017Purpuric lesions appear in acral distribution in a variety of conditions and often provide clues to the clinical diagnosis. Purpuric means "hemorrhagic"-that is, the... (Review)
Review
Purpuric lesions appear in acral distribution in a variety of conditions and often provide clues to the clinical diagnosis. Purpuric means "hemorrhagic"-that is, the lesions do not blanch from pressure. This review focuses on dermatoses that produce hemorrhagic lesions in acral distribution from the large groups of the vasculitic diseases and their mimics. Cutaneous small vessel vasculitis is confined to the skin, involves mainly postcapillary venules, and has the hallmark manifestation of palpable purpura. Henoch-Schönlein purpura is an immune complex-mediated systemic vasculitis of the small vessels with manifestations from the skin, joints, kidneys, and gastrointestinal system. Only cases where the immune complexes contain immunoglobulin A type are classified as Henoch-Schönlein purpura. Cryoglobulinemic vasculitis is induced by the deposition of cold-precipitated immune complexes in the small vessels. Urticarial vasculitis comprises a spectrum of conditions with the characteristic course of chronic urticaria, with wheals that persist longer than 24 hours, leave hyperpigmentation, and have leukocytoclastic vasculitis on histologic examination. Polyarteritis nodosa is a rare multisystem, segmental necrotizing vasculitis of mainly the medium-sized vessels. Pigmented purpuric dermatoses are chronic benign dermatoses characterized by petechiae, purpura, and increased skin pigmentation. The hallmark of pigmented purpuric dermatoses is their orange-brown, speckled, cayenne pepper-like discoloration.
Topics: Arm; Churg-Strauss Syndrome; Embolism; Foot Dermatoses; Granulomatosis with Polyangiitis; Hand Dermatoses; Humans; IgA Vasculitis; Leg Dermatoses; Pigmentation Disorders; Polyarteritis Nodosa; Purpura; Purpura Fulminans; Skin Diseases, Vascular; Vasculitis
PubMed: 27938815
DOI: 10.1016/j.clindermatol.2016.09.013 -
Annals of Internal Medicine Sep 1950
Topics: Humans; Purpura; Purpura, Thrombocytopenic; Purpura, Thrombotic Thrombocytopenic
PubMed: 14771751
DOI: 10.7326/0003-4819-33-3-739 -
Dermatologic Therapy 2011Retiform purpura consists of branching purpuric lesions caused by a complete blockage of blood flow in the dermal and subcutaneous vasculature. The differential... (Review)
Review
Retiform purpura consists of branching purpuric lesions caused by a complete blockage of blood flow in the dermal and subcutaneous vasculature. The differential diagnosis for retiform purpura is broad, including vasculitides of the small and medium vessels as well as microvascular occlusion due to thrombotic, infectious, and embolic phenomena. Determining the etiology of this important dermatologic sign can be a diagnostic challenge; however, an organized approach can improve the speed and accuracy of diagnosis and identify an effective treatment. This review focuses on early recognition, evaluation, and treatment of hospitalized patients with retiform purpura. Specifically, vasculitis, protein C and S deficiencies, heparin necrosis, warfarin necrosis, antiphospholipid antibody syndrome, disseminated intravascular coagulation, cryoglobulinemia, calciphylaxis, and cholesterol embolization syndrome will be discussed in detail. These conditions are commonly seen in consultative dermatology and can have multiorgan involvement, complicated laboratory evaluation, and long-term therapeutic implications.
Topics: Dermatology; Diagnosis, Differential; Early Diagnosis; Hospitals; Humans; Inpatients; Predictive Value of Tests; Purpura; Referral and Consultation; Risk Factors; Skin; Treatment Outcome
PubMed: 21410606
DOI: 10.1111/j.1529-8019.2011.01392.x -
Clinics in Dermatology 2005Palpable purpura, the inflammation of blood vessels is the hallmark of vasculitis. It can be observed in a variety of settings, where vessels can be affected primarily... (Review)
Review
Palpable purpura, the inflammation of blood vessels is the hallmark of vasculitis. It can be observed in a variety of settings, where vessels can be affected primarily or as a secondary event. Every patient with vasculitis should be considered to have a systemic disease unless proven otherwise. One or more systemic symptoms occur in at least 50% of patients and there is no way to predict systemic involvement. Patients may demonstrate mild systemic involvement like arthralgia and arthritis, fever and malaise or more severe symptoms such as massive proteinuria and raised creatinine leading to chronic renal failure, severe intestinal bleeding or perforation with a fatal outcome. In this article we will review the life-threatening aspects of purpura and vasculitis.
Topics: Critical Illness; Humans; Purpura; Vasculitis
PubMed: 15896537
DOI: 10.1016/j.clindermatol.2004.06.002 -
International Journal of Dermatology Oct 2022
Topics: Aged, 80 and over; Female; Humans; Levamisole; Purpura
PubMed: 35106756
DOI: 10.1111/ijd.16120 -
Cutis May 2020
Topics: Aged; Arm; Blood Pressure Determination; Capillaries; Ecchymosis; Humans; Male; Purpura; Skin; Tourniquets; Vascular Diseases
PubMed: 32603394
DOI: No ID Found