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International Journal of Dermatology Jan 1994
Review
Topics: Blood Coagulation Disorders; Humans; Purpura
PubMed: 8112930
DOI: 10.1111/j.1365-4362.1994.tb01483.x -
The Israel Medical Association Journal... May 2009
Topics: Adult; Female; Humans; Purpura; Vomiting
PubMed: 19637517
DOI: No ID Found -
Archives of Dermatology Mar 1961
Topics: Calcaneus; Disease; Foot Diseases; Humans; Hyperpigmentation; Purpura; Skin Diseases
PubMed: 13696488
DOI: 10.1001/archderm.1961.01580090151017 -
Cutis Jun 1978Purpura fulminans is the cutaneous manifestation of acute activation of the clotting mechanism resulting in massive hemorrhage due to an intravascular consumption...
Purpura fulminans is the cutaneous manifestation of acute activation of the clotting mechanism resulting in massive hemorrhage due to an intravascular consumption coagulopathy. Peripheral necrotizing purpura is a warning signal, and early recognition of the clinical situation and heparin therapy may be lifesaving. Clinical manifestations and histologic features of this condition, along with its pathogenesis, treatment, and differential diagnosis are discussed.
Topics: Diagnosis, Differential; Humans; Purpura; Skin
PubMed: 657839
DOI: No ID Found -
Indian Journal of Dermatology,... 2023
Topics: Female; Humans; Purpura
PubMed: 37067121
DOI: 10.25259/IJDVL_784_2022 -
British Journal of Haematology May 2023
Topics: Humans; Purpura; Age Factors
PubMed: 36920454
DOI: 10.1111/bjh.18739 -
American Family Physician Oct 1995Cutaneous vasculitis, secondary to drug reaction, infection or collagen vascular disease, is the most common identifiable cause of palpable purpura. Common causes of... (Review)
Review
Cutaneous vasculitis, secondary to drug reaction, infection or collagen vascular disease, is the most common identifiable cause of palpable purpura. Common causes of palpable purpura often can be identified during the patient's history and physical examination. When this condition occurs in a patient who has not had a known precipitating event, or when the cause is unclear from the history and physical examination, diagnosis may be based on findings of the laboratory investigations and skin biopsy. Many cases of palpable purpura are idiopathic and self-limited. When treatment is necessary, dapsone, colchicine or systemic corticosteroids are useful drugs.
Topics: Algorithms; Diagnosis, Differential; Humans; Medical History Taking; Physical Examination; Purpura
PubMed: 7572558
DOI: No ID Found -
Journal of Pediatric Hematology/oncology Jan 2013Primary immune thrombocytopenia (ITP) is one of the most common bleeding disorders of childhood. In most cases, it presents with sudden widespread bruising and petechiae... (Review)
Review
Primary immune thrombocytopenia (ITP) is one of the most common bleeding disorders of childhood. In most cases, it presents with sudden widespread bruising and petechiae in an otherwise well child. Thought to be mainly a disorder of antibody-mediated platelet destruction, ITP can be self-limited or develop into a chronic condition. In this review, we discuss current concepts of the pathophysiology and treatment approaches to pediatric ITP.
Topics: Child; Humans; Purpura, Thrombocytopenic, Idiopathic
PubMed: 23073045
DOI: 10.1097/MPH.0b013e318271f457 -
The American Journal of Forensic... Sep 1994Petechial hemorrhages are areas of pericapillary bleeding that occur in a wide spectrum of disorders, including some of particular forensic interest. Since their... (Review)
Review
Petechial hemorrhages are areas of pericapillary bleeding that occur in a wide spectrum of disorders, including some of particular forensic interest. Since their potential significance was first recognized by Tardieu in 1855, attention has largely focused on their diagnostic importance. There have been only a few studies of their mechanism of production. Although the pathogenesis of petechiae is often conjectural, it seems that, in spite of their stereotypical gross appearance, a variety of pathogenetic mechanisms may be involved. They range from mechanical disruption of the capillary wall to subtle cellular injury that permits the transit of red blood cells through the endothelial cytoplasm. I discuss several conditions that are commonly encountered in forensic practice, with emphasis on petechial hemorrhages and their pathogenesis.
Topics: Adult; Disseminated Intravascular Coagulation; Embolism, Fat; Humans; Hypoxia; Infant; Infant, Newborn; Purpura; Sudden Infant Death; Thrombocytopenia; Wounds, Nonpenetrating
PubMed: 7825548
DOI: 10.1097/00000433-199409000-00004 -
Journal of Forensic Sciences Nov 2000Conjunctival and facial petechiae, although nonspecific findings, are considered hallmarks of asphyxial deaths. Consensus in the literature suggests that their... (Review)
Review
Conjunctival and facial petechiae, although nonspecific findings, are considered hallmarks of asphyxial deaths. Consensus in the literature suggests that their pathogenesis is related to the combined effects of increased cephalic venous pressure and hypoxic damage to endothelial cells. Despite the common knowledge that they are neither predictable findings in all asphyxial deaths nor rare in natural, nonasphyxial deaths, the belief persists that petechiae are corroborative evidence of asphyxia. We suggest that a clear, physiologically based understanding of the pathogenesis of petechiae of the head is critical for their appropriate interpretation. We present a review of the literature and the basis of our conclusion that conjunctival and facial petechiae are the product of purely mechanical vascular phenomena, unrelated to asphyxia or hypoxia.
Topics: Asphyxia; Autopsy; Cause of Death; Conjunctiva; Forensic Medicine; Humans; Purpura
PubMed: 11110181
DOI: No ID Found