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Medecine Sciences : M/S Oct 2011
Topics: Action Potentials; Animals; Biophysical Phenomena; Channelrhodopsins; Dendrites; Humans; Infrared Rays; Ion Channel Gating; Lasers; Micromanipulation; Microscopy; Neurons; Neurosciences; Optics and Photonics; Photochemistry; Photons; Protein Engineering; Recombinant Fusion Proteins
PubMed: 22027415
DOI: 10.1051/medsci/20112710006 -
Journal of Biomedical Optics Apr 20202019 SPIE Photonics West conference hosted over 5000 presentations. Some important presentations in the Industrial Laser, Laser Source and Application (LASE) and... (Review)
Review
SIGNIFICANCE
2019 SPIE Photonics West conference hosted over 5000 presentations. Some important presentations in the Industrial Laser, Laser Source and Application (LASE) and Optoelectronics, Photonic Materials and Devices (OPTO) sections of the SPIE Photonics West conference have a risk of being overlooked by the biomedical community despite their implications for the field of biophotonics. We review some recent advances in the area of development coherent radiation sources in the infrared (IR), ultraviolet (UV), and terahertz (THz) regimes.
AIM
Recent advances in coherent radiation sources in the IR, deep UV, and THz regimes were outlined, and the importance of each presentation to one or more promising biomedical applications was assessed.
APPROACH
Presentations and proceedings from the LASE and OPTO sections were reviewed for inclusion. Emphasis was placed on talks from the Nonlinear Frequency Generation and Conversion: Materials and Devices XVIII conference, and the Terahertz, RF, Millimeter, and Submillimeter-Wave Technology and Applications XII conference. Conference sections that directly focused on biomedical applications were excluded.
RESULTS
Enhanced IR supercontinuum generation with compact supercontinuum sources may allow for real-time biomarker detection and create new opportunities for imaging tissues using the third biological window (1600 to 1850 nm). Efficient methods to generate deep UV (200 to 260 nm) radiation allow for the study of biologically important molecules through techniques such as resonance Raman spectroscopy while avoiding fluorescence overlap. Likewise, novel and improved THz generation methods seek to bridge the "THz gap" that has previously limited biomedical applications.
CONCLUSIONS
Advances in coherent radiation sources in the IR, UV, and THz regimes have created new opportunities for biomedical optics research.
Topics: Diagnostic Imaging; Lasers; Light; Optics and Photonics; Photons
PubMed: 32329266
DOI: 10.1117/1.JBO.25.4.040902 -
Molecules (Basel, Switzerland) Dec 2020The 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY)-based molecules have emerged as interesting material for optoelectronic applications. The facile structural... (Review)
Review
The 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY)-based molecules have emerged as interesting material for optoelectronic applications. The facile structural modification of BODIPY core provides an opportunity to fine-tune its photophysical and optoelectronic properties thanks to the presence of eight reactive sites which allows for the developing of a large number of functionalized derivatives for various applications. This review will focus on BODIPY application as solid-state active material in solar cells and in photonic devices. It has been divided into two sections dedicated to the two different applications. This review provides a concise and precise description of the experimental results, their interpretation as well as the conclusions that can be drawn. The main current research outcomes are summarized to guide the readers towards the full exploitation of the use of this material in optoelectronic applications.
Topics: Boron Compounds; Fluorescent Dyes; Optics and Photonics; Photons; Solar Energy
PubMed: 33396319
DOI: 10.3390/molecules26010153 -
Nano Letters Jun 2006We realize controlled cavity-mediated photon transfer between two single nanoparticles over a distance of several tens of micrometers. First, we show how a single...
We realize controlled cavity-mediated photon transfer between two single nanoparticles over a distance of several tens of micrometers. First, we show how a single nanoscopic emitter attached to a near-field probe can be coupled to high-Q whispering-gallery modes of a silica microsphere at will. Then we demonstrate transfer of energy between this and a second nanoparticle deposited on the sphere surface. We estimate the photon transfer efficiency to be about 6 orders of magnitude higher than that via free-space propagation at comparable separations.
Topics: Computer Simulation; Equipment Design; Equipment Failure Analysis; Light; Linear Energy Transfer; Materials Testing; Microspheres; Models, Theoretical; Nanostructures; Optics and Photonics; Photons
PubMed: 16771571
DOI: 10.1021/nl060306p -
Optics Express Jan 2012Single Photon Detectors are fundamental to quantum optics and quantum information. Superconducting nanowire detectors exhibit high performance in free-running mode, but...
Single Photon Detectors are fundamental to quantum optics and quantum information. Superconducting nanowire detectors exhibit high performance in free-running mode, but have a limited maximum count rate. By exploiting a bistable superconducting nanowire system, we demonstrate the first gated-mode operation of these detectors for a large active area single element device at 625MHz, one order of magnitude faster than its free-running counterpart. We show the maximum count rate in gated-mode operation can be pushed to GHz range without a compromise on the active area or quantum efficiency, while reducing the dark count rate.
Topics: Computer Simulation; Electric Conductivity; Electronics; Nanowires; Optics and Photonics; Photons; Quantum Theory
PubMed: 22274503
DOI: 10.1364/OE.20.001608 -
Optics Letters Sep 2022We propose a novel, to the best of our knowledge, sensor for nanovibration detection based on a microsphere. The sensor consists of a stretched single-mode fiber and a 2...
We propose a novel, to the best of our knowledge, sensor for nanovibration detection based on a microsphere. The sensor consists of a stretched single-mode fiber and a 2 µm microsphere. The light from the optical fiber passes through the microsphere, forming a photonic nanojet (PNJ) phenomenon at the front of the microsphere. The evanescent field in the PNJ enhances the light reflected from the measured object to the single-mode fiber-microsphere probe (SMFMP). Results showed that the system can detect arbitrary nanovibration waveforms in real time with an SMFMP detection resolution of 1 nm. The voltage signal received and the vibration amplitude showed a good linear relationship within the range of 0-100 nm, with a sensitivity of 0.7 mV/nm and a linearity of more than 99%. The sensor is expected to have potential applications in the field of cell nanovibration detection.
Topics: Microspheres; Optical Fibers; Optics and Photonics; Photons
PubMed: 36048704
DOI: 10.1364/OL.464848 -
Journal of the American Chemical Society May 2022We report a new synthetic strategy of combining -carboxyanhydride (NCA) chemistry and photonic crystals for the fabrication of polypeptide structural color films. Driven...
We report a new synthetic strategy of combining -carboxyanhydride (NCA) chemistry and photonic crystals for the fabrication of polypeptide structural color films. Driven by surface-initiated ring-opening polymerization, the di-NCA derivative of l-cystine (Cys) is introduced to replicate the functionalized colloidal crystal templates and construct freestanding P(Cys) films with tunable structural color. Furthermore, the feasibility of preparing patterned polypeptide photonic films is demonstrated via template microfabrication. Because of the incorporation of l-glutamate (Glu) components, the P(Cys--Glu) co-polypeptide films are endowed with a visual color responsiveness toward pH changes. Additionally, the polypeptide photonic films show on-demand degradability. Given the large family of amino acid building blocks, this powerful and versatile approach paves the way for chemical derivatization of multifunctional peptide-based optical platforms.
Topics: Color; Optics and Photonics; Peptides; Photons; Polymerization
PubMed: 35446030
DOI: 10.1021/jacs.2c02894 -
Optics Express Aug 2010We theoretically investigate coupled Fano structures which combine the characteristics of both directly coupled Fabry-Perot cavities (DCFPC) and a side-coupled...
We theoretically investigate coupled Fano structures which combine the characteristics of both directly coupled Fabry-Perot cavities (DCFPC) and a side-coupled integrated spaced sequence of resonators (SCISSOR). Asymmetric and symmetric Fano resonances in a single and doubly-coupled Fano unit are analytically derived based on Fabry-Perot approach. It is found that doubly-coupled Fano units show a special asymmetric EIT-like lineshape. This structure shows an index changing sensitivity of 10(-6), about two orders higher than that of the single Fano resonator, which is promising for index sensor application. A unique frequency detuning method of EIT like lineshape is also found in the doubly-coupled Fano units. The multiple coupled Fano unit structure demonstrates potentials for applications of tunable optical filter and slow light, whereas for the latter it shows much higher group delay than that of SCISSORS and DCFPC with the same parameters.
Topics: Algorithms; Biosensing Techniques; Equipment Design; Light; Optics and Photonics; Photons; Transducers
PubMed: 20940775
DOI: 10.1364/OE.18.018820 -
Applied Optics Jun 2007An axial superresolution diffraction theory is developed in a two-photon microfabrication system. This method can improve the axial superresolution of the two-photon...
An axial superresolution diffraction theory is developed in a two-photon microfabrication system. This method can improve the axial superresolution of the two-photon microfabrication system. A theoretical analysis of the photosensitive resin is discussed based on the exciting power and the concentration of free radical theory. Simulated results of the two-photon microfabrication verify the method and show that it can provide insight into the microfabrication system.
Topics: Chemistry, Physical; Computer Simulation; Electrons; Light; Models, Statistical; Optics and Photonics; Photochemistry; Photons; Resins, Synthetic; Software
PubMed: 17538663
DOI: 10.1364/ao.46.003694 -
Journal of Biophotonics Oct 2010
Topics: Molecular Imaging; Nanotechnology; Optics and Photonics; Photons
PubMed: 20860049
DOI: 10.1002/jbio.201000521