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The Kaohsiung Journal of Medical... Oct 2018
Topics: Adult; Chordoma; Humans; Magnetic Resonance Imaging; Male; Optic Chiasm; Sphenoid Sinus; Vision Disorders; Visual Fields
PubMed: 30309489
DOI: 10.1016/j.kjms.2018.03.003 -
Current Hypertension Reports Apr 2024This review summarizes key findings relating to the association between preeclampsia and retinal disorders. (Review)
Review
PURPOSE OF REVIEW
This review summarizes key findings relating to the association between preeclampsia and retinal disorders.
RECENT FINDINGS
Preeclampsia is a major cause of maternal morbidity. Pregnant women with preeclampsia frequently describe having visual disturbances. Retinal changes can be identified on fundoscopy in most patients with preeclampsia. While retinal pathology secondary to preeclampsia usually resolves postpartum, there is growing evidence that women with preeclampsia have a higher long-term risk of developing retinal disorders after pregnancy. Pregnant women often experience visual changes. While these symptoms may be benign, careful attention should be paid to exclude retinal disorders secondary to preeclampsia. Pregnant women complaining of new-onset or worsening blurry vision, scotomata, diplopia, or photopsia require rapid and thorough evaluation to rule out hypertensive disorders. Management of preeclampsia, including administration of magnesium sulfate and delivery of the fetus, can reverse retinal pathologies in most cases.
Topics: Female; Humans; Pregnancy; Pre-Eclampsia; Hypertension; Vision Disorders; Retina
PubMed: 38133842
DOI: 10.1007/s11906-023-01290-0 -
Journal of Ocular Pharmacology and... Aug 2010A 56-year-old woman presented with photopsia and color changes in the left eye that had been present since starting voriconazole treatment 5 months earlier. The patient...
SUMMARY STATEMENT
A 56-year-old woman presented with photopsia and color changes in the left eye that had been present since starting voriconazole treatment 5 months earlier. The patient was seen in ophthalmologic follow-up 7 and 20 months after discontinuation of voriconazole with persistent visual complaints, including photopsia and "additional sources of light" in her left eye.
PURPOSE
To describe a case of persistent photopsia following course of oral voriconazole.
METHODS
The medical records of a patient with voriconazole treatment and persistent photopsia were reviewed.
RESULTS
Persistent photopsia and visual complaints were noted 20 months after discontinuation of voriconazole.
CONCLUSIONS
In light of increasing use of voriconazole to combat fungal infections, voriconazole-related photopsia may persist in certain patients.
Topics: Administration, Oral; Antifungal Agents; Female; Histoplasmosis; Humans; Middle Aged; Ocular Physiological Phenomena; Pyrimidines; Treatment Outcome; Triazoles; Vision Disorders; Voriconazole
PubMed: 20653481
DOI: 10.1089/jop.2010.0046 -
Medicines (Basel, Switzerland) Jan 2023Choroidal melanoma is a rare malignant tumour, yet it is the most common primary intra-ocular neoplasm and second on the list of top ten most malignant melanoma sites in... (Review)
Review
Choroidal melanoma is a rare malignant tumour, yet it is the most common primary intra-ocular neoplasm and second on the list of top ten most malignant melanoma sites in the body. Clinical presentation can be non-specific and includes photopsia, floaters, progressive visual field loss, and blurry vision. The tumour is quite often diagnosed clinically during fundus examination; however, the most valued diagnostic tests are A- and B-scan ultrasonography (US). Several factors affect prognosis, including the patient's age, tumour size, histological features, and presence of metastases. Still, with primary treatment and tight surveillance, around 50% of choroidal melanoma patients metastasise.
PubMed: 36662495
DOI: 10.3390/medicines10010011 -
Journal of Clinical Psychopharmacology Oct 2006
Topics: Adult; Antipsychotic Agents; Dibenzothiazepines; Dose-Response Relationship, Drug; Humans; Male; Psychotic Disorders; Quetiapine Fumarate; Vision Disorders
PubMed: 16974209
DOI: 10.1097/01.jcp.0000237949.88387.9e -
Canadian Journal of Ophthalmology.... Oct 2006To present a case of photopsia resulting from digoxin intoxication brought about by dehydration in a 72-year-old woman.
CASE REPORT
To present a case of photopsia resulting from digoxin intoxication brought about by dehydration in a 72-year-old woman.
COMMENTS
Ophthalmologists may be the first clinicians to notice the symptoms of digitalis intoxication, which is potentially a life-threatening condition.
Topics: Aged; Cardiotonic Agents; Dehydration; Digoxin; Female; Fluid Therapy; Hallucinations; Humans; Phosphenes
PubMed: 17016533
DOI: 10.1016/S0008-4182(06)80031-1 -
Der Ophthalmologe : Zeitschrift Der... Jan 2016Acute annular outer retinopathy (AAOR) is a very rare variant of acute zonal occult outer retinopathy (AZOOR). Both variants are characterized by the perception of a...
Acute annular outer retinopathy (AAOR) is a very rare variant of acute zonal occult outer retinopathy (AZOOR). Both variants are characterized by the perception of a progressive visual field defect and can be accompanied by photopsia. In contrast to AZOOR, a progressive whitish and annular demarcation of the involved retina is observed in AAOR using ophthalmoscopy. Optical coherence tomography (OCT) reveals morphological changes predominantly in the outer retinal layers. Although there is no proof of an effective therapy, in the case presented here further progression could be stopped by a combination of antiviral and immunosuppressive therapy.
Topics: Adult; Antiviral Agents; Diagnosis, Differential; Hallucinations; Humans; Immunosuppressive Agents; Male; Ophthalmoscopy; Scotoma; Tomography, Optical Coherence; Treatment Outcome; White Dot Syndromes
PubMed: 25930180
DOI: 10.1007/s00347-015-0012-z -
Asia-Pacific Journal of Ophthalmology... 2017The appearance of a dark shadow in the temporal periphery, otherwise known as negative dysphotopsia, continues to be a problem for some patients after routine... (Review)
Review
The appearance of a dark shadow in the temporal periphery, otherwise known as negative dysphotopsia, continues to be a problem for some patients after routine uncomplicated cataract surgery. Etiologies include type and design of intraocular lens (IOL), anatomical features and dimensions of the eye, pupil size, angle kappa, relationship of the optic to the anterior capsule, and the position of the optic/haptic junction of the IOL. Although the primary etiology remains controversial, it is clear that the cause is multifactorial. All of the factors should be considered when attempting to prevent or treat this phenomenon.
Topics: Cataract Extraction; Humans; Lenses, Intraocular; Pseudophakia; Vision Disorders; Visual Acuity; Visual Fields
PubMed: 28726357
DOI: 10.22608/APO.2017111 -
International Journal of Retina and... 2018Autoimmune retinopathy (AIR) is a rare and still poorly understood immune-mediated disease that may cause inflammation from circulating autoantibodies against the... (Review)
Review
Autoimmune retinopathy (AIR) is a rare and still poorly understood immune-mediated disease that may cause inflammation from circulating autoantibodies against the retina. It may be related to history of autoimmune disease in the patient or in a family member or the presence of neoplastic disease in the individual. The disease may be subdivided into paraneoplastic and non-paraneoplastic AIR. When related to melanoma, it is referred to as MAR, and when related to other cancers, it is called CAR. The exact prevalence of AIR is unknown. It mainly affects older adults. Patients present with bilateral and asymmetric scotomas, photopsias, visual field defects, with rapidly progressive visual loss in late onset. In the initial stage, fundus examination is unremarkable, and in late stages, there is limited retinal epitheliopathy and vascular attenuation, with or without optic disc pallor, associated or not with intraocular inflammation and with no evidence of degenerative retinal disease. A clinical investigation with detailed anamnesis and laboratory tests should be performed to search for an associated neoplasm. Ophthalmologic and complementary examinations such as full-field electroretinogram, optical coherence tomography, visual field and fundus autofluorescence, help the diagnosis. Blood tests to search for autoantibodies should be requested. Management consists of prolonged immunosuppression, which may be combined with antioxidant vitamins. In general, the prognosis is uncertain, so the disease still needs to be better understood. More studies should be performed to improve diagnostic measures and define specific management that could preserve or even restore vision.
PubMed: 29340169
DOI: 10.1186/s40942-017-0104-9