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Klinische Wochenschrift May 1991Oral contraceptives are being associated with an increased risk of thrombosis. Measurements of clotting factor abnormalities in plasma can not predict the individual... (Review)
Review
Oral contraceptives are being associated with an increased risk of thrombosis. Measurements of clotting factor abnormalities in plasma can not predict the individual risk of thrombosis, nor can they explain the pathophysiology of the clinically known association of thrombosis and oral contraceptives. Research conducted over the last 10 years points to the important role of endothelial cells, fibroblasts and monocytes in the regulation of the initiation of coagulation. Hence we propose, that the molecular mechanism of oral contraceptive associated thrombosis can only be elucidated by studies looking at the effect of these drugs on cellular elements involved in coagulation. Measurements of plasmatic coagulation factors can not indicate safety or risk for a patient taking any of the multiple drugs available.
Topics: Blood Coagulation Factors; Contraceptives, Oral; Endothelium, Vascular; Female; Humans; Risk Factors; Thrombosis
PubMed: 1886397
DOI: 10.1007/BF02115778 -
People 1978
Topics: Contraceptives, Oral; Female; Humans; Neoplasms; Thrombophlebitis
PubMed: 720732
DOI: No ID Found -
Prescribers' Journal Feb 1970
Topics: Blood Coagulation; Contraception; Contraceptives, Oral; Contraceptives, Oral, Combined; Contraceptives, Oral, Hormonal; Data Collection; Disease; Embolism; Family Planning Services; Research; Sampling Studies; Thromboembolism; Thrombophlebitis; Thrombosis; Vascular Diseases
PubMed: 12254686
DOI: No ID Found -
Journal de Gynecologie, Obstetrique Et... Dec 2005
Topics: Adult; Contraceptives, Oral; Contraceptives, Oral, Combined; Female; Humans; Neoplasms; Risk Factors
PubMed: 16319761
DOI: 10.1016/s0368-2315(05)82946-1 -
British Medical Journal Jul 1970
Topics: Breast Neoplasms; Contraceptives, Oral; Female; Humans
PubMed: 5431096
DOI: 10.1136/bmj.3.5715.165-c -
British Medical Journal May 1970
Topics: Child, Preschool; Contraceptives, Oral; Ethics, Medical; Female; Humans; Public Opinion
PubMed: 5420182
DOI: 10.1136/bmj.2.5704.294 -
British Medical Journal Jul 1967
Topics: Contraceptives, Oral; Humans; Pigmentation Disorders
PubMed: 6028739
DOI: 10.1136/bmj.3.5560.307-a -
Current Opinion in Obstetrics &... Apr 1990
Review
Topics: Clinical Trials as Topic; Contraception; Contraceptive Devices, Male; Contraceptives, Oral; Female; Humans; Intrauterine Devices, Copper; Male
PubMed: 2102326
DOI: No ID Found -
Nursing Times
Topics: Contraceptives, Oral; Female; Humans; Infertility, Female; Luteinizing Hormone
PubMed: 1994340
DOI: No ID Found -
Journal of the National Cancer Institute Feb 1989
Topics: Breast Neoplasms; Contraceptives, Oral; Female; Humans; Risk Factors
PubMed: 2913323
DOI: 10.1093/jnci/81.4.256