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Dermatologic Therapy Jan 2021Dermoscopy as a diagnostic tool is attaining impetus in inflammatory dermatoses with the cumulative description of characteristic findings in most dermatoses obviating... (Observational Study)
Observational Study
Dermoscopy as a diagnostic tool is attaining impetus in inflammatory dermatoses with the cumulative description of characteristic findings in most dermatoses obviating at times the need of biopsy. In this retrospective observational study, 20 histopathology confirmed cases each of pityriasis rosea (PR), guttate psoriasis (GP), and pityriasis lichenoides chronica (PLC) seen over a period of 3 years were included. Dermoscopy images were extracted from photography archives for evaluation and three lesions from each patient (60 lesions each) were analyzed. Comparison of dermoscopy characters was done among PR, GP, and PLC in pairs using chi-square test and a P-value of less than .05 was considered significant. Most common background color in PR (86.7%) and PLC (96.7%) was yellow to yellow-orange and in GP was dull red to pink (70%). Vessels were visualized in all lesions of GP and most characteristic pattern was regular (93.3%), dotted vessels (95%). In PR 63.3% lesions had dotted vessels mostly in a patchy distribution (56.7%). Most prominent scale color in PR was yellow-white (88.3%) and in GP was white-gray (80%). In PLC varying colors were seen, most prominent being brown (53.3%). Characteristic findings seen only in PLC were hypopigmented areas (13.3%), brown dots and globules (53.3%) and orange-yellow structureless areas (61.7%) GP, PR, and PLC reveal specific dermoscopic findings that can help in differentiating them. Further, the known dermoscopic criteria for GP, PR, and PLC also apply for dark skin phototypes.
Topics: Dermoscopy; Exanthema; Humans; Pityriasis Lichenoides; Pityriasis Rosea; Psoriasis
PubMed: 33277950
DOI: 10.1111/dth.14631 -
The British Journal of Dermatology Dec 1977Circulating immune complexes have been detected in patients with pityriasis lichenoides during disease activity when IgM and C3 have been observed in dermal vessels on...
Circulating immune complexes have been detected in patients with pityriasis lichenoides during disease activity when IgM and C3 have been observed in dermal vessels on direct immunofluorescence of fresh lesions. This implies that pityriasis lichenoides is an immune complex disorder and that deposited complexes play a part in the pathogenesis of the condition. There is a characteristic pattern of immunofluorescence which may be a diagnostic aid.
Topics: Adolescent; Adult; Aged; Antigen-Antibody Complex; Child; Complement C3; Female; Fluorescent Antibody Technique; Humans; Immune Complex Diseases; Immunoglobulin M; Male; Middle Aged; Pityriasis
PubMed: 146510
DOI: 10.1111/j.1365-2133.1977.tb14269.x -
International Journal of Dermatology May 1999
Topics: Adult; Animals; Anti-Infective Agents; Antibodies, Protozoan; Humans; Male; Pityriasis Lichenoides; Spiramycin; Toxoplasma; Toxoplasmosis; Trimethoprim, Sulfamethoxazole Drug Combination
PubMed: 10369549
DOI: 10.1046/j.1365-4362.1999.00670.x -
Pediatric Dermatology 2012We present two pediatric patients with pityriasis lichenoides et varioliformis acuta fulminans whose admitting diagnosis was Stevens Johnson Syndrome. The patients were... (Review)
Review
We present two pediatric patients with pityriasis lichenoides et varioliformis acuta fulminans whose admitting diagnosis was Stevens Johnson Syndrome. The patients were successfully treated with methotrexate and prednisone. These cases highlight the importance of early recognition and treatment of this disease to prevent further morbidity and a potentially fatal prognosis.
Topics: Anti-Bacterial Agents; Clindamycin; Dermatologic Agents; Drug Therapy, Combination; Female; Herpes Simplex; Humans; Infant; Methotrexate; Pityriasis Lichenoides; Prednisone; Skin Ulcer; Stevens-Johnson Syndrome; Treatment Outcome; Vancomycin
PubMed: 22084981
DOI: 10.1111/j.1525-1470.2011.01608.x -
Cutis Mar 2010Pityriasis lichenoides chronica (PLC) is a cutaneous disease of unknown etiology that most commonly affects children and young adults. The highly variable presentation...
Pityriasis lichenoides chronica (PLC) is a cutaneous disease of unknown etiology that most commonly affects children and young adults. The highly variable presentation of this condition often poses a diagnostic challenge. The clinical presentation of PLC in black patients is not well described. We report a series of 5 black patients (4 children and 1 young adult) with PLC who presented with extensive hypopigmentation and prominent facial involvement. One patient had concomitant mycosis fungoides (MF). The diagnosis of PLC should be included in the differential diagnosis in dark-skinned patients who present with widespread hypopigmented macules and patches. The presence of MF in one of our patients underscores the potential relationship between MF and PLC.
Topics: Adult; Black People; Child; Child, Preschool; Female; Humans; Hypopigmentation; Male; Mycosis Fungoides; Pityriasis Lichenoides; Skin Neoplasms
PubMed: 20408509
DOI: No ID Found -
Open Access Macedonian Journal of... Jan 2019Pityriasis lichenoides et varioliformis acuta (PLEVA) is an uncommon condition which presents acutely with papulo-vesicles that may develop necrotic, ulcerative, or...
BACKGROUND
Pityriasis lichenoides et varioliformis acuta (PLEVA) is an uncommon condition which presents acutely with papulo-vesicles that may develop necrotic, ulcerative, or hemorrhagic changes.
AIM
We studied clinical, and treatment characteristics of PLEVA hospitalised patients at our hospital from September 2009 to December 2014.
METHODS
The records of 15 PLEVA patients were retrospectively reviewed.
RESULTS
The median age of onset was 21.8 ± 18.81 (from 1 to 68), male to female ratio was 2/1. The common area of onset was trunk (60.0%) and extremities (33.3%). Clinical features were purpuric papules (100%), hemorrhagic crusted papules (46.7%), pustular purpuric papules (40%), and necrotic ulcerating lesions (13.3%).
CONCLUSION
All patients were received systemic antibiotics (macrolides: 53.3%, others: 46.7%), 2 patients were added immunosuppressive drugs. A 1-year-old patient died, others had a good response.
PubMed: 30745957
DOI: 10.3889/oamjms.2019.005 -
Dermatologic Therapy Jun 2022
Topics: COVID-19; Humans; Pityriasis Lichenoides; RNA, Messenger; Vaccination
PubMed: 35286000
DOI: 10.1111/dth.15445 -
International Journal of Dermatology Sep 2016
Topics: Adult; Anti-Bacterial Agents; Female; Humans; Male; Middle Aged; Minocycline; Pityriasis Lichenoides
PubMed: 27261329
DOI: 10.1111/j.1365-4632.2010.04659.x -
The American Journal of Dermatopathology Dec 2021A 15-year-old boy presented to the pediatric dermatology department with long-standing patch stage CD8+ mycosis fungoides and subsequent development of recurrent...
A 15-year-old boy presented to the pediatric dermatology department with long-standing patch stage CD8+ mycosis fungoides and subsequent development of recurrent pityriasis lichenoides et varioliformis acuta eruptions. There have been rare reports of patients with chronic, recalcitrant pityriasis lichenoides developing mycosis fungoides, but we believe this to be the second case of mycosis fungoides preceding a diagnosis of pityriasis lichenoides, and the first case reported in the pediatric population.
Topics: Adolescent; Humans; Male; Mycosis Fungoides; Pityriasis Lichenoides; Skin Neoplasms
PubMed: 33795555
DOI: 10.1097/DAD.0000000000001949 -
JAAD Case Reports May 2024
PubMed: 38576898
DOI: 10.1016/j.jdcr.2024.02.021