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Drug-induced pityriasis lichenoides from infliximab in a patient with juvenile idiopathic arthritis.JAAD Case Reports May 2022
PubMed: 35402674
DOI: 10.1016/j.jdcr.2022.02.017 -
Journal of Cutaneous Pathology Apr 2016
Review
Topics: Female; Humans; Lymphomatoid Papulosis; Male; Pityriasis Lichenoides
PubMed: 26566599
DOI: 10.1111/cup.12653 -
Pediatric Dermatology Jul 2020Although the clinical presentations of patients with pityriasis lichenoides et varioliformis acuta (PLEVA) may vary, bullae are not usually part of the clinical...
Although the clinical presentations of patients with pityriasis lichenoides et varioliformis acuta (PLEVA) may vary, bullae are not usually part of the clinical spectrum. To date, only two other cases of a bullous variant of PLEVA with evidence of autoantibodies against hemidesmosomal antigens have been reported. The term PLEVA pemphigoides was suggested for this unique clinical, pathological and serological combination of both PLEVA and bullous pemphigoid.
Topics: Humans; Pemphigoid, Bullous; Pityriasis Lichenoides
PubMed: 32350916
DOI: 10.1111/pde.14181 -
The American Journal of Surgical... Aug 2018Pityriasis lichenoides (PLs) is an uncommon skin disease of unknown etiology. In recent years, an atypical form of PL has been described, showing overlapping features...
Pityriasis lichenoides (PLs) is an uncommon skin disease of unknown etiology. In recent years, an atypical form of PL has been described, showing overlapping features with mycosis fungoides (MF) and lymphomatoid papulosis. We studied 66 patients with an initial histopathologic diagnosis of PL (M:F=34:32; median age, 25 y; range, 7 to 85 y). According to clinical and phenotypic features, cases were classified into 4 categories: (1) Conventional PL (characteristic clinical features of PL without phenotypic aberrations) (n=20; M:F=8:12; median age, 37 y; range, 9 to 74 y); (2) Atypical form of PL (characteristic clinical features of PL with phenotypic aberrations) (n=25; M:F=16:9; median age, 21 y; range, 7 to 72 y). Four of these patients subsequently developed MF; (3) Lymphomatoid papulosis (waxing and waning lesions and positivity for CD30) (n=10; M:F=4:6; median age, 41 y; range, 16 to 83 y); (4) MF (clinical features typical of MF) (n=11; M:F=6:5; median age, 17 y; range, 8 to 85 y). Molecular analyses of clonality of the infiltrate did not reveal relevant differences among these 4 groups. Our study suggests that patients with an initial histopathologic diagnosis of PL may belong to different groups, showing that clinicopathologic correlation and complete phenotypic analyses are paramount in order to achieve proper classification. Although the relationship between PL and MF is yet a matter of debate, at the present state of knowledge, patients with a clinicopathologic presentation consistent with PL but with aberrant phenotypic features should be monitored in order to detect a possible evolution into MF.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biopsy; Child; Disease Progression; Female; Gene Rearrangement, T-Lymphocyte; Genes, T-Cell Receptor; Genetic Markers; Genetic Predisposition to Disease; Humans; Immunohistochemistry; Lymphomatoid Papulosis; Male; Middle Aged; Multiplex Polymerase Chain Reaction; Mycosis Fungoides; Phenotype; Pityriasis Lichenoides; Skin; Skin Neoplasms; Young Adult
PubMed: 29851705
DOI: 10.1097/PAS.0000000000001093 -
Archives of Dermatology May 1983Eleven patients with chronic pityriasis lichenoides chronica were treated with topically applied bland emollient cream and minimally erthemogenic doses of UV radiation...
Eleven patients with chronic pityriasis lichenoides chronica were treated with topically applied bland emollient cream and minimally erthemogenic doses of UV radiation from fluorescent sunlamps. The conditions of all patients cleared completely in an average of 29 treatments, requiring an average UV dose of 388 millijoules/sq cm at clearance. Phototherapy provides a convenient effective outpatient therapy for pityriasis lichenoides chronica.
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Humans; Male; Middle Aged; Parapsoriasis; Radiotherapy Dosage; Ultraviolet Therapy
PubMed: 6847216
DOI: No ID Found -
JAAD Case Reports Oct 2023
PubMed: 37701883
DOI: 10.1016/j.jdcr.2023.07.038 -
Dermatology Practical & Conceptual Jan 2017Pityriasis lichenoides is an uncommon skin disease that presents in three different forms: pityriasis lichenoides et varioliformis acuta (PLEVA), pityriasis lichenoides...
BACKGROUND
Pityriasis lichenoides is an uncommon skin disease that presents in three different forms: pityriasis lichenoides et varioliformis acuta (PLEVA), pityriasis lichenoides chronica (PLC) and febrile ulceronecrotic-Mucha-Habermann disease. These represent a spectrum of a disease. PLEVA presents as skin eruption of multiple, small, red papules that develop into polymorphic lesions with periods of varying remissions, as well as possible sequels of hyper/hypopigmentation and varicella-like scars. Diagnosis of this condition is mainly clinical, and sometimes clinical differentiation from other conditions may be a difficult task that often requires histological analysis. In this study, PLEVA lesions were examined by dermoscopy, and the significance of specific dermoscopic findings was investigated in order to facilitate their differentiation from other inflammatory conditions.
OBJECTIVES
To evaluate dermoscopic patterns in PLEVA and to correlate these patterns with histopathology.
MATERIALS AND METHODS
The study was conducted at S. Nijalingappa Medical College, Bagalkot. It was an observational case series study and patients were selected randomly. Ethical clearance and informed consent were obtained. PLEVA lesions in early and late phases were evaluated. A manual DermLite 3 (3Gen, San Juan Capistrano, CA) dermoscope attached to a Sony (Cyber Shot DSC-W800, Sony Electronics Inc., San Diego, California, USA, digital, 14 mega pixels) camera was employed. Histopathology was done to confirm the diagnosis. Data was collected and analyzed. Results were statistically described in terms of frequencies and types of dermoscopic patterns.
RESULTS
There was a total of 14 patients; 8 males and 6 females. Mean age of patients was 19 years. Mean duration of disease was 7 months. Dermoscopy in early-phase lesions revealed amorphous brownish areas around the hair follicles, dotted vessels, and scaling. Dermoscopy in late-phase lesions showed whitish-structureless areas and central white crust within whitish-structureless rim with scale, focal bluish-grayish areas or centrifugal strands irregularly distributed along the periphery and yellow structures. Red dots and hemorrhage were seen at the center and glomerular vessels at the periphery.
CONCLUSION
PLEVA demonstrates specific dermoscopic patterns that correlate well with histologic changes. New dermoscopic findings are described. Thus, dermoscopy is a good diagnostic tool in the clinical diagnosis of PLEVA.
PubMed: 28243491
DOI: 10.5826/dpc.0701a05 -
Journal of Drugs in Dermatology : JDD Mar 2020Pityriasis lichenoides is a scarce cutaneous disorder with unknown etiology. It contains a range of clinical manifestations including acute papular lesions that quickly...
Pityriasis lichenoides is a scarce cutaneous disorder with unknown etiology. It contains a range of clinical manifestations including acute papular lesions that quickly grow into pseudo vesicles and central necrosis to small, scaling, benign-appearing papules.1,2.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diagnosis, Differential; Etanercept; Female; Humans; Pityriasis Lichenoides; Spondylitis, Ankylosing
PubMed: 32550684
DOI: No ID Found -
Anais Brasileiros de Dermatologia 2020
Topics: Adrenal Cortex Hormones; Adult; Antimetabolites; Diphtheria-Tetanus Vaccine; Epidermis; Humans; Male; Necrosis; Pityriasis Lichenoides
PubMed: 32156502
DOI: 10.1016/j.abd.2019.06.009 -
Journal of the American Academy of... Aug 2003Pityriasis lichenoides is a rare cutaneous eruption of unknown cause that spans a spectrum of clinical severity. Infectious agents have long been suspected as etiologic... (Review)
Review
Pityriasis lichenoides is a rare cutaneous eruption of unknown cause that spans a spectrum of clinical severity. Infectious agents have long been suspected as etiologic factors. The present case is the first to demonstrate a known EBV-mediated process evolving and resolving in concert with pityriasis lichenoides. Epstein-Barr virus, Toxoplasma gondii, and HIV are the most frequently reported infectious triggers of pityriasis lichenoides. Pityriasis lichenoides may arise secondary to EBV-mediated acute infectious mononucleosis.
Topics: Adult; Biopsy, Needle; Female; Follow-Up Studies; Herpesvirus 4, Human; Humans; Infectious Mononucleosis; Pityriasis Lichenoides; Risk Assessment; Severity of Illness Index; Treatment Outcome; Ultraviolet Therapy
PubMed: 12894107
DOI: 10.1067/mjd.2003.337