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La Revue Du Praticien Mar 2007Pleurisy is a common syndrome revealing or complicating numerous diseases. It is suspected on dyspnea or chest pain, with or without dullness to percussion. Diagnosis is... (Review)
Review
Pleurisy is a common syndrome revealing or complicating numerous diseases. It is suspected on dyspnea or chest pain, with or without dullness to percussion. Diagnosis is confirmed almost always by chest roentgenogram but CT scan and echography can help in case of small pleural effusion. Etiologic research is based on pleural fluid analysis. The dosages of protein and LDH separate transudate from exsudate. Cellular differential count and bacterial and mycobacterial culture must systematically be performed. Other pleural analysis are discussed when specific illness are suspected. In case of exsudative pleural effusion, histological examination of pleural tissue sample is often necessary. Despite the etiological search, some pleurisy remains without specific diagnosis and necessitate a prolonged follow up with sometimes repeated thoracocentesis or biopsy. Treatment of pleurisy is based on the treatment of the underlying disease and the evacuation of pleural fluid.
Topics: Biopsy; Humans; Pleura; Pleurisy; Radiography, Thoracic; Thoracoscopy; Ultrasonography
PubMed: 17583134
DOI: No ID Found -
Veterinary Research Apr 2020Diseases of the respiratory system are known to negatively impact the profitability of the pig industry, worldwide. Considering the relatively short lifespan of pigs,...
Diseases of the respiratory system are known to negatively impact the profitability of the pig industry, worldwide. Considering the relatively short lifespan of pigs, lesions can be still evident at slaughter, where they can be usefully recorded and scored. Therefore, the slaughterhouse represents a key check-point to assess the health status of pigs, providing unique and valuable feedback to the farm, as well as an important source of data for epidemiological studies. Although relevant, scoring lesions in slaughtered pigs represents a very time-consuming and costly activity, thus making difficult their systematic recording. The present study has been carried out to train a convolutional neural network-based system to automatically score pleurisy in slaughtered pigs. The automation of such a process would be extremely helpful to enable a systematic examination of all slaughtered livestock. Overall, our data indicate that the proposed system is well able to differentiate half carcasses affected with pleurisy from healthy ones, with an overall accuracy of 85.5%. The system was better able to recognize severely affected half carcasses as compared with those showing less severe lesions. The training of convolutional neural networks to identify and score pneumonia, on the one hand, and the achievement of trials in large capacity slaughterhouses, on the other, represent the natural pursuance of the present study. As a result, convolutional neural network-based technologies could provide a fast and cheap tool to systematically record lesions in slaughtered pigs, thus supplying an enormous amount of useful data to all stakeholders in the pig industry.
Topics: Abattoirs; Animals; Neural Networks, Computer; Pleurisy; Pneumonia; Sus scrofa; Swine; Swine Diseases
PubMed: 32276670
DOI: 10.1186/s13567-020-00775-z -
Revue Des Maladies Respiratoires Sep 2016Whereas numerous case reports have described statin-induced lung injuries, statin-induced pleural effusions are uncommon.
INTRODUCTION
Whereas numerous case reports have described statin-induced lung injuries, statin-induced pleural effusions are uncommon.
CASE REPORT
An 84-year-old man presented with bilateral pleural effusions two years after starting treatment with atorvastatin. No other cause of pleural effusion was found and all symptoms and radiological signs resolved rapidly after discontinuation of the drug. Furthermore, an accidental reintroduction of the treatment resulted in recurrence of the same clinical picture, reinforcing the hypothesis that atorvastatin was responsible for this pleural effusion.
CONCLUSION
Pleuropulmonary manifestations in a patient treated with atorvastatin should rapidly evoke an iatrogenic origin and the discontinuation of the drug should be discussed.
Topics: Aged, 80 and over; Atorvastatin; Humans; Male; Pleurisy; Radiography, Thoracic
PubMed: 26992330
DOI: 10.1016/j.rmr.2015.12.010 -
Thoracic Cancer Apr 2022Pleural biopsies for investigating the causes of pleurisy are performed through modalities including needle biopsies, local anesthetic thoracoscopic procedures, and...
BACKGROUND
Pleural biopsies for investigating the causes of pleurisy are performed through modalities including needle biopsies, local anesthetic thoracoscopic procedures, and surgery (video-assisted thoracoscopic surgery and open thoracotomy). To date, there have been no large-scale nationwide epidemiological studies regarding pleurisy diagnosed via surgical pleural biopsy. This study examined the epidemiology of pleurisy diagnosed via surgical pleural biopsy in a Japanese nationwide administrative database.
METHODS
We evaluated Japanese Diagnosis Procedure Combination data of 24 173 patients who underwent video-assisted thoracoscopic surgery or open thoracotomy and received a diagnosis of pleurisy between April 2014 and March 2020. In addition to pleurisy diagnoses, the patients' clinical information, including age, sex, smoking status (pack-years), dyspnea grade, length of in-hospital stay, and comorbidities, were extracted from the dataset.
RESULTS
This study included data from 1699 patients. The most frequent causes of pleurisy were neoplastic diseases (55.9%; malignant mesothelioma 22.5%, lung cancer 15.7%, lymphoma 2.5%), followed by infectious diseases (24.0%; tuberculosis 16.2%, parapneumonic pleural effusion 3.6%, empyema 3.5%, nontuberculous mycobacteriosis 0.5%), collagen vascular diseases (2.8%; rheumatoid arthritis 1.3%, immunoglobulin G4-related diseases 0.7%, systemic lupus erythematosus 0.3%), and paragonimiasis (0.1%).
CONCLUSIONS
Neoplastic diseases, including malignant mesothelioma and lung cancer, were frequently and accurately diagnosed as pleurisy via surgical pleural biopsy. The next leading cause was infectious diseases such as mycobacterial infections. Physicians should consider performing surgical biopsy in light of the knowledge regarding the etiology of pleurisy when a definitive diagnosis cannot be made via needle pleural biopsy.
Topics: Biopsy; Humans; Lung Neoplasms; Mesothelioma, Malignant; Pleural Effusion; Pleurisy; Thoracic Surgery, Video-Assisted
PubMed: 35243795
DOI: 10.1111/1759-7714.14368 -
Meditsinskaia Sestra Mar 1978
Topics: Humans; Pleurisy
PubMed: 247164
DOI: No ID Found -
Revue de Pneumologie Clinique Nov 2001The primary cancer remains unknown in about 7% of all cases of metastatic carcinomatous pleurisy. Thoracoscopic pleural biopsy provide good quality histology material.... (Review)
Review
The primary cancer remains unknown in about 7% of all cases of metastatic carcinomatous pleurisy. Thoracoscopic pleural biopsy provide good quality histology material. The pathology examination, including immunohistochemistry using a panel of well-defined antibodies can provide the diagnosis of neoplastic pleurisy of malignant carcinomatous proliferation, and help search for differentiation and rule out an identifiable primary carcinoma. When histology does not provide a satisfactory clue to the primary cancer, frequent origins include lung cancer, breast or ovary cancer in women, prostate cancer in men, and digestive tract cancer. The possible contribution of positron emission tomography remains to be evaluated. Several chemotherapy protocols can be proposed but the beneficial effect has been difficult to assess due to the heterogeneous nature of the histological forms treated. The carboplatin-paclitaxel-etoposide protocol appears to be promising in cases with an unknown primary cancer but there has been no specific assessment of this chemotherapy schedule in a subgroups of patients with carcinomatous pleurisy with an unknown primary cancer. Better understanding of the biological profile of highly metastatic cancers should be helpful in determining more targeted therapeutic schemes.
Topics: Humans; Neoplasms, Unknown Primary; Pleurisy
PubMed: 11924229
DOI: No ID Found -
Nihon Yakurigaku Zasshi. Folia... Aug 1997Mediators involved in acute inflammation were explored by using rat pleurisies induced by carrageenin or zymosan. The kallikrien-kinin system and eicosanoids were the... (Review)
Review
Mediators involved in acute inflammation were explored by using rat pleurisies induced by carrageenin or zymosan. The kallikrien-kinin system and eicosanoids were the main mediators responsible for plasma exudation in carrageenin-induced rat pleurisy, while histamine, PAF and the complement system could be the main mediators involved in the vascular permeability increase to cause plasma exudation into the pleural cavity in zymosan-induced rat pleurisy. Several chemokines were detected in the pleural exudates of carrageenin-pleurisy as well as those of zymosan-pleurisy; and exogenous recombinant TNF alpha, IL-1, IL-6 and CINC induced neutrophil migration into rat pleural cavity. These results suggest that these chemokines, directly or indirectly, may partly cause neutrophil migration in the pleural exudates during carrageenin- and zymosan-induced pleurisy. In addition, chemokine production in response to prostanoids and PAF production in response to arachidonic acid were also suggested.
Topics: Animals; Arachidonic Acid; Capillary Permeability; Carrageenan; Cell Movement; Chemokines; Complement System Proteins; Disease Models, Animal; Eicosanoids; Histamine; Inflammation; Kallikrein-Kinin System; Male; Neutrophils; Platelet Activating Factor; Pleurisy; Rats; Zymosan
PubMed: 9306414
DOI: 10.1254/fpj.110.59 -
Revue de Pneumologie Clinique 1991The authors report a case of bilateral purulent pleurisy consecutive to spontaneous rupture of the oesophagus (Boerhaave's syndrome). In such cases Mackler's triad, when... (Review)
Review
The authors report a case of bilateral purulent pleurisy consecutive to spontaneous rupture of the oesophagus (Boerhaave's syndrome). In such cases Mackler's triad, when complete, confirms the diagnosis. Standard radiography of the chest remains essential as it shows, at an early stage, the presence of mediastinal emphysema.
Topics: Adult; Esophageal Diseases; Humans; Male; Pleurisy; Radiography; Rupture, Spontaneous; Suppuration; Syndrome
PubMed: 1882163
DOI: No ID Found -
Scandinavian Journal of Rheumatology 1983In 157 women and 77 men with rheumatoid arthritis, observed for a mean of 5.7 years, the annual incidence of pleural effusion was found to be 0.34% in the women and...
In 157 women and 77 men with rheumatoid arthritis, observed for a mean of 5.7 years, the annual incidence of pleural effusion was found to be 0.34% in the women and 1.54% in the men. In 4 pleural fluids the fluid-to-serum ratio for Waaler-Rose titres was 1:4, which agrees with the ratios for other proteins and does not suggest a pathogenetic role of the rheumatoid factor. In two other pleural fluids the findings suggested immune mechanisms implicating the rheumatoid factor. In general, the data, both clinical and any other, was compatible with the possibility of multiple etiological and pathogenetic factors in rheumatoid pleural effusions. These were: extrinsic factors causing pleural thickenings in 25% of non-rheumatoid men and in less than 10% of non-rheumatoid women aged more than 50 years; preceding lung disorder; particular inflammatory responsiveness due to rheumatoid disease, related or unrelated to rheumatoid factor; and some degree of transudation.
Topics: Adolescent; Adult; Aged; Aging; Arthritis, Rheumatoid; Child; Denmark; Female; Humans; Male; Middle Aged; Pleural Effusion; Pleurisy; Rheumatoid Factor; Sex Factors
PubMed: 6857177
DOI: 10.3109/03009748309102888 -
Surgical Infections Apr 2016
Topics: Aged; Candida albicans; Enterococcus faecium; Fistula; Humans; Male; Pancreatic Diseases; Pleurisy; Radiography, Abdominal; Radiography, Thoracic; Tomography, X-Ray Computed
PubMed: 26828566
DOI: 10.1089/sur.2015.156