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Nordisk Medicin Dec 1962
Topics: Papilloma; Podophyllin; Podophyllum; Urinary Bladder Neoplasms
PubMed: 13955977
DOI: No ID Found -
HNO Aug 1956
Topics: Fibroma; Humans; Laryngeal Neoplasms; Larynx; Papilloma; Podophyllin; Precancerous Conditions
PubMed: 13366107
DOI: No ID Found -
Zeitschrift Fur Urologie 1953
Topics: Podophyllin; Urinary Bladder Neoplasms
PubMed: 13103642
DOI: No ID Found -
The Journal of Urology Aug 1952
Topics: Adenocarcinoma; Podophyllin; Urinary Bladder Neoplasms
PubMed: 14955876
DOI: 10.1016/S0022-5347(17)68225-9 -
Singapore Medical Journal Jan 1998The aims of this study were to: 1) ascertain if podophyllin resin in 0.5% [PE(0.5%)] and 0.25% [PE(0.25%)] in ethanol (PE) self-applied sequentially for 3 days with 4... (Clinical Trial)
Clinical Trial Comparative Study
AIM
The aims of this study were to: 1) ascertain if podophyllin resin in 0.5% [PE(0.5%)] and 0.25% [PE(0.25%)] in ethanol (PE) self-applied sequentially for 3 days with 4 days break cycle is as effective as supervised podophyllin 25% in tincture benzoin (PB) applied in the clinic biweekly in treating penile warts and 2) ascertain if PE causes less skin irritation than PB.
METHODS AND RESULTS
The clearance rate of penile warts was 36.4% (4/11) in PE (0.5%) treated group, 66.7% (4/6) in the PE (0.25%) treated group and 33.3% (6/18) for PB treated group after 1 week (ns). The wart clearance rate at 6 weeks for PE (0.5%) treated group, PE (0.25%) treated group and PB treated group were 81.8% (9/11), 100% (6/6) and 83.3% (15/17) respectively (ns). There were 47 individual warts on the penis of the 17 patients in the PE treated group and 58 individual warts on the penis of the 18 patients in the PB treated group. Based on the response of individual warts to the 2 treatment regimens, the clearance rate was 42.6% (20/47) for the PE treated group and 25% (15/56) for the PB treated group after 1 week treatment (ns). At 6 weeks follow-up, the clearance rate for the PE treated group and the PB treated group were 85.1% (40/47) and 73.2% (41/56) respectively (ns). Skin irritation including superficial erosions, pain and itch were observed in 47% (8/17) in patients treated with PE compared to 38.9% (7/18) in patients treated with PB (ns) during the 6 weeks follow-up period. The clearance rate of patients treated with PE (0.25%) was compared to those treated with PE (0.5%). Four out of six of PE (0.25%) treated patients had clearance of warts after 1 week and 100% clearance at the end of 6 weeks. None experienced any skin irritation.
CONCLUSION
This study demonstrates that 0.5% podophyllin (and possibly 0.25% podophyllin) in ethanol is effective in eradicating penile warts. It can be used by patients for self-treatment at home with greater convenience and is more cost effective than the conventional podophyllin 25% in tincture benzoin paint.
Topics: Adult; Aged; Condylomata Acuminata; Emollients; Ethanol; Humans; Keratolytic Agents; Male; Middle Aged; Penile Diseases; Plant Extracts; Podophyllin; Solvents; Styrax
PubMed: 9557098
DOI: No ID Found -
Acta Dermato-venereologica 1948
Topics: Condylomata Acuminata; Humans; Podophyllin; Podophyllum
PubMed: 18100125
DOI: No ID Found -
Gut Sep 1996
Review
Topics: Cathartics; Colonic Diseases; Humans; Podophyllin; Substance-Related Disorders
PubMed: 8949659
DOI: 10.1136/gut.39.3.486 -
Muscle & Nerve Apr 1992
Topics: Adult; Ataxia; Electromyography; Female; H-Reflex; Humans; Neural Conduction; Peripheral Nervous System Diseases; Podophyllin
PubMed: 1314329
DOI: 10.1002/mus.880150417 -
Ugeskrift For Laeger Feb 1980
Topics: Adult; Cornea; Corneal Diseases; Female; Humans; Iritis; Podophyllin
PubMed: 7368397
DOI: No ID Found -
The British Journal of Venereal Diseases Oct 1984
Topics: Anus Diseases; Drug Therapy, Combination; Humans; Podophyllin; Trichloroacetic Acid; Warts
PubMed: 6487991
DOI: 10.1136/sti.60.5.351