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Neuroradiology 1991A case of toxic encephalopathy due to podophyllin poisoning was presented. It is documented for the first time by MRI that diffuse cerebral atrophy occurred as a result...
A case of toxic encephalopathy due to podophyllin poisoning was presented. It is documented for the first time by MRI that diffuse cerebral atrophy occurred as a result of podophyllin toxicity.
Topics: Adult; Atrophy; Brain; Brain Diseases; Humans; Magnetic Resonance Imaging; Male; Podophyllin; Poisoning; Substance-Related Disorders
PubMed: 1922761
DOI: 10.1007/BF00587830 -
Vestnik Dermatologii I Venerologii Jan 1980
Topics: Adult; Female; Hemangioma; Humans; Male; Podophyllin; Skin Neoplasms; Vulvar Neoplasms
PubMed: 7368869
DOI: No ID Found -
Journal of Acquired Immune Deficiency... 1991
Topics: AIDS-Related Complex; Adult; Drug Evaluation; Humans; Leukoplakia, Oral; Male; Middle Aged; Podophyllin
PubMed: 2016695
DOI: No ID Found -
Lancet (London, England) Aug 1987
Clinical Trial Comparative Study Randomized Controlled Trial
Topics: Clinical Trials as Topic; Follow-Up Studies; Humans; Male; Penile Diseases; Podophyllin; Podophyllotoxin; Random Allocation; Recurrence; Warts
PubMed: 2887805
DOI: 10.1016/s0140-6736(87)91823-x -
Mutation Research Apr 1992Podophyllin, a plant derivative of variable composition, is used widely within New Zealand as a treatment for genital warts. One local source of podophyllin has been...
Podophyllin, a plant derivative of variable composition, is used widely within New Zealand as a treatment for genital warts. One local source of podophyllin has been tested for ability to cause mutagenic effects in Salmonella typhimurium as well as for effects on chromosomes of Chinese hamster AA8 cells. Although only weakly mutagenic in one strain of Salmonella, podophyllin caused structural aberrations as well as changes in chromosome number in the Chinese hamster cells. The range of aberrations was similar to those caused by teniposide, a close structural relative of the major component, which was used as a positive control in the Chinese hamster cell experiments. A literature review revealed that podophyllin was shown to cause changes of chromosome number in the mouse cervix in vivo, although aberrations were not studied. Patients treated with podophyllin will usually possess one form of the papilloma virus, and this itself may have some oncogenic potential. We suggest that podophyllin could potentiate these effects and question its continued widespread use.
Topics: Animals; Cells, Cultured; Chromosome Aberrations; Condylomata Acuminata; Cricetinae; Cricetulus; Mutagenicity Tests; Podophyllin
PubMed: 1373833
DOI: 10.1016/0027-5107(92)90191-4 -
Comptes Rendus Des Seances de La... May 1951
Topics: Cytokinesis; Ovum; Podophyllin; Polyethylene Glycols; Spindle Poles
PubMed: 14859634
DOI: No ID Found -
Rhode Island Medical Journal Feb 1947
Topics: Condylomata Acuminata; Humans; Podophyllin; Skin Diseases
PubMed: 20285496
DOI: No ID Found -
A.M.A. Archives of Dermatology and... Oct 1950
Topics: Carcinoma; Humans; Podophyllin; Skin; Skin Neoplasms
PubMed: 14770486
DOI: 10.1001/archderm.1950.01530170052006 -
International Journal of STD & AIDS 1995
Comparative Study
Topics: Condylomata Acuminata; Cost-Benefit Analysis; Female; Humans; Male; Podophyllin; Podophyllotoxin
PubMed: 7647132
DOI: 10.1177/095646249500600320 -
Toxicology and Applied Pharmacology Feb 1974
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Female; Fetal Death; Fetus; Mice; Mice, Inbred DBA; Podophyllin; Pregnancy; Vinblastine
PubMed: 4851785
DOI: 10.1016/0041-008x(74)90211-7