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Paediatrica Indonesiana 1968
Topics: Brain; Brain Diseases; Cerebral Ventriculography; Diagnosis, Differential; Female; Humans; Hydrocephalus; Infant; Male
PubMed: 5300893
DOI: No ID Found -
Indian Pediatrics May 2002
Topics: Adolescent; Brain Diseases; Cysts; Diagnosis, Differential; Electroencephalography; Humans; Male; Tomography, X-Ray Computed
PubMed: 12037285
DOI: No ID Found -
Neurocase Dec 2020Colpocephaly is a form of congenital ventriculomegaly while porencephaly describes any full-thickness defect within the brain which usually presents as a cystic...
Colpocephaly is a form of congenital ventriculomegaly while porencephaly describes any full-thickness defect within the brain which usually presents as a cystic structure. Postulated aetologies include intrauterine/perinatal injuries, genetic disorders, and morphogenesis error. Colopocephaly and porencephaly is typically diagnosed in infancy while diagnosis in adulthood is exceptionally rare. We report a case of co-existence of colpocephaly with porencephaly diagnosed incidentally in a 54-year-old male presenting with subtle cognitive and neurologic abnormalities. Neuropsychological assessment revealed weaknesses in executive functions, processing speed, and language.To our knowledge, this is the only reported case of dual incidental findings of porencephaly and colpocephaly in an adult.
Topics: Age of Onset; Brain Diseases; Cognitive Dysfunction; Humans; Lateral Ventricles; Magnetic Resonance Imaging; Male; Middle Aged; Porencephaly
PubMed: 33136527
DOI: 10.1080/13554794.2020.1841798 -
Computerized Radiology : Official... 1987Twenty-six cases of porencephalic cysts were analyzed. The cysts were multiple in 26.9% and were associated with subarachnoid cysts in 11.5%. The main presentations were...
Twenty-six cases of porencephalic cysts were analyzed. The cysts were multiple in 26.9% and were associated with subarachnoid cysts in 11.5%. The main presentations were seizures, cerebral palsy and mental retardation. The unifocal cysts were mainly in the frontoparietal region, suggesting a congenital aetiology. Multiple cysts were noted in the basal ganglia region. A case of multiloculated cysts, of unknown aetiology, is noted. The aetiology of multifocal porencephaly and a diagnostic method of differentiating congenital from acquired porencephaly are discussed.
Topics: Adolescent; Adult; Brain; Brain Diseases; Child; Child, Preschool; Cysts; Female; Humans; Infant; Infant, Newborn; Male; Retrospective Studies; Tomography, X-Ray Computed
PubMed: 3581816
DOI: 10.1016/0730-4862(87)90030-8 -
Pediatric Neurology Mar 2004Fetal stroke, or that which occurs between 14 weeks of gestation and the onset of labor resulting in delivery, has been associated with postnatal epilepsy, mental... (Review)
Review
Fetal stroke, or that which occurs between 14 weeks of gestation and the onset of labor resulting in delivery, has been associated with postnatal epilepsy, mental retardation, and cerebral palsy. The entity is caused by antenatal ischemic, thrombotic, or hemorrhagic injury. We present seven new cases of fetal stroke diagnosed in utero and review the 47 cases reported in the literature. Although risk factors could not be assigned to 50% of the fetuses with stroke, the most common maternal conditions associated with fetal stroke were alloimmune thrombocytopenia and trauma. Magnetic resonance imaging was optimal for identifying fetal stroke, and prenatal imaging revealed hemorrhagic lesions in over 90% of studies; porencephalies were identified in just 13%. Seventy-eight percent of cases with reported outcome resulted in either death or adverse neurodevelopmental outcome at ages 3 months to 6 years. Fetal stroke appears to have different risk factors, clinical characteristics, and outcomes than other perinatal or childhood stroke syndromes. A better understanding of those risk factors predisposing a fetus to cerebral infarction may provide a basis for future therapeutic intervention trials. Ozduman K, Pober BR, Barnes P, Copel JA, Ogle EA, Duncan CC, Ment LR. Fetal stroke.
Topics: Brain; Cerebral Palsy; Child; Child, Preschool; Developmental Disabilities; Female; Fetal Diseases; Follow-Up Studies; Humans; Infant; Infant, Newborn; Intellectual Disability; Magnetic Resonance Imaging; Male; Pregnancy; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Risk Factors; Spasms, Infantile; Stroke; Survival Rate; Ultrasonography, Prenatal
PubMed: 15033196
DOI: 10.1016/j.pediatrneurol.2003.08.004 -
Radiology Mar 1967
Topics: Adult; Aged; Bone Cysts; Cerebral Hemorrhage; Cerebral Ventriculography; Humans; Male; Middle Aged; Skull
PubMed: 5297568
DOI: 10.1148/88.3.526 -
BMC Veterinary Research Dec 2012Seizures are a common problem in small animal neurology and it may be related to underlying diseases. Porencephaly is an extremely rare disorder, and in Veterinary...
BACKGROUND
Seizures are a common problem in small animal neurology and it may be related to underlying diseases. Porencephaly is an extremely rare disorder, and in Veterinary Medicine it affects more often ruminants, with only few reports in dogs.
CASE PRESENTATION
A one-year-old intact male Shih-Tzu dog was referred to Veterinary University Hospital with history of abnormal gait and generalized tonic-clonic seizures. Signs included hypermetria, abnormal nystagmus and increased myotatic reflexes. At necropsy, during the brain analysis, a cleft was observed in the left parietal and occipital lobes, creating a communication between the subarachnoid space and the left lateral ventricle, consistent with porencephaly; and also a focal atrophy of the caudal paravermal and vermal portions of the cerebellum. Furthermore, the histological examination showed cortical and cerebellar neuronal dysplasia.
CONCLUSIONS
Reports of seizures due to porencephaly are rare in dogs. In this case, the dog presented a group of brain abnormalities which per se or in assemblage could result in seizure manifestation.
Topics: Animals; Brain Diseases; Dog Diseases; Dogs; Male; Malformations of Cortical Development; Seizures
PubMed: 23269021
DOI: 10.1186/1746-6148-8-246 -
Clinical Neurology and Neurosurgery 1987A formal inquiry on the health state of 1206 legally adopted children from Indonesia revealed cerebral palsy in 9 (0.9% of 1029 responses obtained), including two who...
A formal inquiry on the health state of 1206 legally adopted children from Indonesia revealed cerebral palsy in 9 (0.9% of 1029 responses obtained), including two who had died. CT examination performed in 7 cases was abnormal in all. Four types of lesions were seen: 1. Bilateral full thickness porencephalies (BFTP lesion) in 4 cases, amounting to 0.4% of the total population on which response was obtained. 2. Full thickness porencephaly of the area of one internal carotid artery in 1 case. 3. Schizencephaly-like lesion in 1 case, confirmed by magnetic resonance imaging. 4. Supratentorial midline cyst resulting in hydrocephalus. The frequency of the BFTP lesion found in 4 out of 7 cerebral palsied investigated by CT is remarkable in view of its rarity in radiological studies on cerebral palsy and because of its relationship to prenatal rather than perinatal damage according to previous pathological studies. This is the first systematic study on the neurodevelopmental outcome of a group of adopted babies which indicates an increased risk to specific prenatal brain damage.
Topics: Adoption; Brain; Cerebral Palsy; Female; Humans; Indonesia; Infant; Infant, Newborn; Male; Tomography, X-Ray Computed
PubMed: 3568516
DOI: 10.1016/s0303-8467(87)80070-7 -
Autopsy & Case Reports 2022
PubMed: 35350817
DOI: 10.4322/acr.2021.351 -
Acta Neuropathologica Aug 1978Twenty necropsy cases of the association of fetal encephalitis with porencephaly, hydranencephaly or polymicrogyria were reviewed including 5 from the authors' material....
Twenty necropsy cases of the association of fetal encephalitis with porencephaly, hydranencephaly or polymicrogyria were reviewed including 5 from the authors' material. The latter include a basket brain, a porencephalic necrosis of recent date and a polymicrogyria in the formative state. The supratentorial lesions are often associated with cerebellar cortical dysplasias. The pathogenetic interdependence of encephalitis and hemispheric defects or malformation is discussed. Examples are given in which the infection appears to be secondary to a pre-existent hemispheric lesion. For others the hemispheric lesions appear to be secondary to encephalitis. In these the encephalitis may produce secondary lesions by a variety of pathogenetic mechanisms.
Topics: Brain; Cerebellar Cortex; Cerebral Cortex; Encephalitis; Female; Fetal Diseases; Humans; Pregnancy
PubMed: 567000
DOI: 10.1007/BF00685011