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Journal of Cutaneous Pathology Feb 2001"Apocrine" poroma has recently been proposed as a new term to designate a distinctive benign skin neoplasm with differentiation toward the folliculosebaceous-apocrine... (Review)
Review
BACKGROUND
"Apocrine" poroma has recently been proposed as a new term to designate a distinctive benign skin neoplasm with differentiation toward the folliculosebaceous-apocrine unit.
CASE REPORT
In support of alternative differentiation, a case of apocrine poroma is reported in a 73-year-old man. A nodule on the right upper abdomen, which was thought clinically to be seborrheic keratosis or basal cell epithelioma, was excised.
HISTOLOGY
Histologically, this neoplasm heterogeniously consisted of poroma-like, sebaceous and follicular epithelial components. Since these components share the common embryologic origin of the folliculosebaceous-apocrine unit, this histologic pattern indicates apocrine differentiation of the tumor.
CONCLUSION
This is an additional case to support the term "apocrine" poroma as a diagnosis.
Topics: Acrospiroma; Aged; Apocrine Glands; Carcinoma, Basal Cell; Diagnosis, Differential; Granuloma, Pyogenic; Humans; Keratosis, Seborrheic; Male; Melanoma; Sweat Gland Neoplasms; Treatment Outcome
PubMed: 11168759
DOI: 10.1034/j.1600-0560.2001.280207.x -
Ophthalmic Plastic and Reconstructive... 2008A 71-year-old white woman sought treatment for poroma of the right lower eyelid. Excisional biopsy was performed, and the specimen had histologic features consistent...
A 71-year-old white woman sought treatment for poroma of the right lower eyelid. Excisional biopsy was performed, and the specimen had histologic features consistent with poroma. One year after excision, there has been no recurrence of the lesion. Clinicians should be aware that poroma can occur in regions other than the hands and feet.
Topics: Acrospiroma; Aged; Eyelid Neoplasms; Female; Humans; Sweat Gland Neoplasms
PubMed: 18209652
DOI: 10.1097/IOP.0b013e31816102c8 -
Clinical, Cosmetic and Investigational... 2023Eccrine poroma (EP) is a benign skin appendicular tumor that differentiates into the terminal sweat duct and is often differentiated from basal cell carcinoma (BCC) and...
Eccrine poroma (EP) is a benign skin appendicular tumor that differentiates into the terminal sweat duct and is often differentiated from basal cell carcinoma (BCC) and seborrheic keratosis. This report describes a 58-year-old woman who presented with left occipital plaque. Histopathological analysis showed that the tumor cells were located in the lower part of the epidermis. The tumor cells were cuboidal or circular basal-like cells of the same size. The surrounding cells were not arranged in a palisade shape. Scattered tumor clusters composed of basal-like cells were also seen in the dermis, staining basophilic, and the surrounding cells were arranged in a palisade pattern. Immunohistochemistry showed that BerEP4, epithelial membrane antigen EMA, carcinoembryonic antigen CEA, Bcl-2, CD10, CK7 were positive, AR, PAS were negative. According to the pathological examination and immunohistochemical results, a case of eccrine poroma with concurrent basal cell carcinoma was diagnosed.
PubMed: 37881203
DOI: 10.2147/CCID.S428611 -
Archives of Craniofacial Surgery Mar 2017Eccrine poroma is a common benign cutaneous tumor that originates in an intraepidermal eccrine duct. This tumor exhibits acral distribution (sole, palm), and is rarely...
Eccrine poroma is a common benign cutaneous tumor that originates in an intraepidermal eccrine duct. This tumor exhibits acral distribution (sole, palm), and is rarely encountered in the head and neck area. In fact eccrine poroma in the postauricular area has only been rarely reported. A 55-year-old female visited our hospital with a main complaint of a mass that first developed in the left postauricular area about a year previously. The mass was painless, soft, protruding, domed, and dark red in color, and had slowly enlarged (at presentation it measured 1×1 cm). Excisional biopsy was performed. Histological examination showed distinct features, and eccrine poroma was diagnosed. Follow-up at 6 months postoperatively showed no recurrence. The frequency of eccrine poroma is dependent on eccrine sweat glands density, and thus, usually occurs on the palms or soles. For eccrine poroma in the head and neck region, the differential diagnosis must rule out other masses, such as nevus, skin tag, pyogenic granuloma, cyst, basal cell carcinoma, and seborrheic keratosis. Importantly, 18% of poromas show malignant transformation, and can develop into porocarcinoma. For these reasons, an eccrine poroma in the facial area requires histological examination, complete excision, and follow-up.
PubMed: 28913302
DOI: 10.7181/acfs.2017.18.1.44 -
Journal of the American Podiatric... Nov 1989
Topics: Adenoma, Sweat Gland; Adult; Diagnosis, Differential; Female; Foot Diseases; Humans; Male; Middle Aged; Sweat Gland Neoplasms
PubMed: 2558166
DOI: 10.7547/87507315-79-11-568 -
Journal of Cutaneous Medicine and... 2022
Topics: Adult; Biopsy; Diagnosis, Differential; Female; Foot Dermatoses; Humans; Photography; Poroma; Sweat Gland Neoplasms
PubMed: 32955357
DOI: 10.1177/1203475420960435 -
Journal of Computer Assisted TomographyThe purpose of this study was to evaluate magnetic resonance (MR) imaging findings of poroma and porocarcinoma.
PURPOSE
The purpose of this study was to evaluate magnetic resonance (MR) imaging findings of poroma and porocarcinoma.
METHODS
Six patients (3 male, 3 female; age range, 40-84 years; mean age, 61 years) with histologically confirmed skin appendage tumors with apocrine and eccrine differentiation (2 poromas and 4 porocarcinomas) were enrolled. All patients underwent preoperative MR imaging and the MR images were retrospectively reviewed.
RESULTS
The configurations were classified as pedunculated solid in 5 lesions and subcutaneous cystic with mural nodules in 1. Well-demarcated deep tumor margins and smooth skin surfaces were observed in all 6 lesions, and peritumoral fat stranding was observed in 2. In all 5 pedunculated solid lesions, T2-hyperintense foci, T1 hyperintensity, and homogeneous solid components were observed within the lesions.
CONCLUSIONS
Poroma and porocarcinoma usually exhibited pedunculated solid homogeneous lesion. Intratumoral T2-hyperintense foci and T1 hyperintensity were observed in pedunculated solid lesions.
Topics: Adult; Aged; Aged, 80 and over; Diagnosis, Differential; Eccrine Porocarcinoma; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Poroma; Retrospective Studies; Sweat Gland Neoplasms
PubMed: 33797441
DOI: 10.1097/RCT.0000000000001146 -
Clinical and Experimental Dermatology Sep 2023
Topics: Humans; Poroma; Dermoscopy; Carcinoma, Basal Cell; Skin Neoplasms; Sweat Gland Neoplasms; Diagnosis, Differential
PubMed: 37401454
DOI: 10.1093/ced/llad225 -
Actas Dermo-sifiliograficas May 2021
PubMed: 33964220
DOI: 10.1016/j.ad.2020.01.018 -
American Journal of Clinical Pathology Nov 1961
Topics: Acrospiroma; Adenoma, Sweat Gland; Foot; Foot Diseases; Humans; Medical Records; Neoplasms; Poroma; Skin Neoplasms; Sweat Gland Neoplasms
PubMed: 13894902
DOI: 10.1093/ajcp/36.5.444