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JAAD Case Reports Aug 2021
PubMed: 34258345
DOI: 10.1016/j.jdcr.2021.06.003 -
The American Journal of Dermatopathology Oct 2023
Topics: Humans; Keratosis, Seborrheic; Poroma; Immunohistochemistry; Diagnosis, Differential; Skin Neoplasms; Eccrine Porocarcinoma; Carcinoma in Situ; Sweat Gland Neoplasms; GATA3 Transcription Factor
PubMed: 37506277
DOI: 10.1097/DAD.0000000000002503 -
The Journal of Dermatology Apr 2021
Topics: Humans; Poroma; Sebaceous Gland Neoplasms; Skin Neoplasms; Sweat Gland Neoplasms
PubMed: 33560547
DOI: 10.1111/1346-8138.15791 -
BMJ Case Reports Mar 2019
Topics: Breast Neoplasms; Female; Humans; Medical Illustration; Middle Aged; Nipples; Poroma; Sweat Gland Neoplasms
PubMed: 30826784
DOI: 10.1136/bcr-2018-228665 -
Medical Journal, Armed Forces India Jul 2021Eccrine poroma is a rare tumor arising from sweat glands with common location being soles and palms. We are reporting a case of 70-year male patient with large lower lid...
Eccrine poroma is a rare tumor arising from sweat glands with common location being soles and palms. We are reporting a case of 70-year male patient with large lower lid mass lesion. Owing to its location and history of growth, malignancy was suspected. Biopsy proved it to be eccrine poroma which is a benign lesion. Complete excision with lid reconstruction was done. Eccrine poroma, though rare, should be kept in the differential diagnosis of eyelid tumors. Owing to the risk of malignant transformation and difficulty in clinical differentiation between poroma and porocarcinoma, wide excision should be done.
PubMed: 34305294
DOI: 10.1016/j.mjafi.2020.07.012 -
Journal of the European Academy of... Nov 2002Malignant eccrine poroma is a rare skin appendage tumour, originating from the intraepidermal and upper dermal eccrine ducts. The tumour either arises spontaneously or... (Review)
Review
Malignant eccrine poroma is a rare skin appendage tumour, originating from the intraepidermal and upper dermal eccrine ducts. The tumour either arises spontaneously or develops in a long-standing eccrine poroma, generally in elderly people over 60. Clinically, it tends to be a localized lesion, which manifests itself as a nodule or ulcerated tumour, favouring extremities. We report an 83-year-old female with an enlarging and bleeding tumour on her lumbosacral region. This lesion first appeared as a small pigmented papule and progressed to an erythematous patch with central papular portion and some peripheral pigmentation. Histopathology revealed malignant eccrine poroma. Also, immunohistochemically, diffuse and intense p53 staining was observed. Regular pigment pattern, brown globules and black dots were seen in dermoscopic examination. After performing a wide excision, 20 months of follow-up revealed no recurrence or metastasis of the tumour. This case represents an unusually located malignant eccrine poroma with some pigmentation.
Topics: Acrospiroma; Aged; Aged, 80 and over; Female; Humans; Lumbosacral Region; Sweat Gland Neoplasms; Sweat Glands
PubMed: 12482052
DOI: 10.1046/j.1468-3083.2002.00521.x -
Anais Brasileiros de Dermatologia 2017Eccrine poromas and porocarcinomas are adnexal tumors derived from the sweat duct epithelium. However, eccrine poroma is benign in nature, whilst eccrine porocarcinoma...
Eccrine poromas and porocarcinomas are adnexal tumors derived from the sweat duct epithelium. However, eccrine poroma is benign in nature, whilst eccrine porocarcinoma is regarded as its malignant counterpart. We report the case of a man who presented simultaneously with an eccrine poroma and eccrine porocarcinoma. Both lesions had no clear distinctive features, enhancing the need of high-level clinical suspicion together with surgical excision and histopathology for prompt diagnosis confirmation.
Topics: Aged; Biopsy; Diagnosis, Differential; Eccrine Porocarcinoma; Humans; Male; Neoplasms, Multiple Primary; Poroma; Sweat Gland Neoplasms
PubMed: 28954110
DOI: 10.1590/abd1806-4841.20175719 -
Cutis Nov 2011The eccrine poroma is an uncommon benign neoplasm previously thought to originate solely from the eccrine sweat gland. Initially believed to present on hairless acral... (Review)
Review
The eccrine poroma is an uncommon benign neoplasm previously thought to originate solely from the eccrine sweat gland. Initially believed to present on hairless acral surfaces, a more extensive distribution has been described. We report a case of a 55-year-old man with a slowly growing, 6-cm eccrine poroma on the medial aspect of his right foot of 40 years' duration. Clinicians should be aware that poromas can be of either eccrine or apocrine origin and can occur in areas other than acral skin. They also should understand the subclassification of the poroma family of neoplasms.
Topics: Diagnosis, Differential; Foot; Humans; Male; Middle Aged; Poroma; Sweat Gland Neoplasms
PubMed: 22272484
DOI: No ID Found -
Journal of Cutaneous Pathology Jan 2022Merkel cell polyomavirus (MCPyV) has been studied in several malignant and nonmalignant tissues. However, only in Merkel cell carcinoma (MCC) has the connection to...
BACKGROUND
Merkel cell polyomavirus (MCPyV) has been studied in several malignant and nonmalignant tissues. However, only in Merkel cell carcinoma (MCC) has the connection to tumorigenesis been established. Previously, eccrine porocarcinoma samples were shown to express MCPyV in the majority of samples. We aimed to examine MCPyV in porocarcinoma and poroma samples using MCC as the reference material.
METHODS
We analyzed 17 porocarcinoma and 50 poroma samples for the presence of MCPyV using LT antigen immunostaining and DNA detection methods. In addition, 180 MCC samples served as controls.
RESULTS
MCPyV LT antigen immunostaining was detected in 10% of poroma and 18% of porocarcinoma samples; on the other hand, it was present in 65% of MCC samples. MCPyV DNA was detected in only 10% of poroma and porocarcinoma samples compared with 96% of MCC samples. The viral DNA copy number in all MCPyV DNA-positive MCCs was at least 25 times higher than that in porocarcinoma or poroma samples with the highest MCPyV DNA-to-PTPRG ratio.
CONCLUSIONS
The low number of viral DNA copies in poroma and porocarcinoma samples, together with the negative LT expression of MCPyV DNA-positive tumors, indicates that MCPyV is simply a passenger virus rather than an oncogenic driver of porocarcinoma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Carcinoma, Merkel Cell; Child; Eccrine Porocarcinoma; Female; Humans; Male; Merkel cell polyomavirus; Middle Aged; Polyomavirus Infections; Sweat Gland Neoplasms; Tumor Virus Infections
PubMed: 34313332
DOI: 10.1111/cup.14109 -
Experimental Dermatology Nov 2023
Topics: Humans; Poroma; Imaging, Three-Dimensional; Diagnosis, Differential; Sweat Gland Neoplasms; Microscopy, Confocal
PubMed: 37750378
DOI: 10.1111/exd.14936