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Anais Brasileiros de Dermatologia 2019Eccrine porocarcinoma (EPC) is a rare malignant skin tumor. The dermoscopy of invasive EPC reveals focal presence of whitish-pink, structureless areas surrounded by...
Eccrine porocarcinoma (EPC) is a rare malignant skin tumor. The dermoscopy of invasive EPC reveals focal presence of whitish-pink, structureless areas surrounded by pinkish-white halos. In an eccrine poroma (EP), such areas present diffuse distribution in the "frog- eggs" pattern. We reported an EPC in situ that presents a transitional dermoscopy pattern between EP and invasive EPC. We found a diffuse distribution; whitish-pink, structureless areas surrounded by pinkish-white halos; a central exulceration and a polymorphic vascular pattern.
Topics: Aged; Biopsy; Dermoscopy; Diagnosis, Differential; Eccrine Porocarcinoma; Female; Humans; Leg; Poroma; Sweat Gland Neoplasms
PubMed: 31090833
DOI: 10.1590/abd1806-4841.20197280 -
Dermatology Practical & Conceptual Oct 2019Eccrine poroma (EP) is a benign adnexal neoplasm that can be pigmented in 17% of cases. Four histopathological variants of EP exist. Dermoscopically, EP can mimic many...
BACKGROUND
Eccrine poroma (EP) is a benign adnexal neoplasm that can be pigmented in 17% of cases. Four histopathological variants of EP exist. Dermoscopically, EP can mimic many other skin neoplasms.
OBJECTIVES
To provide a dermoscopic-histopathological correlation of EP, classifying the clinical and dermoscopic features of EPs on the basis of their histopathological subtype, in an attempt to better characterize these entities.
PATIENTS AND METHODS
A single-center retrospective study was conducted. Clinical data were collected; patients were classified on the basis of the 4 histopathological variants of EPs. Dermoscopic images were reviewed. A dermoscopic-histopathological correlation was performed, and the results were compared with literature data.
RESULTS
Twenty-six lesions were included, both pigmented and nonpigmented. Three of the 4 histopathological variants were identified. Different dermoscopic features were observed for each distinct histopathological subtype of EP. The lesions mimicked different types of other skin neoplasms, in particular: nonpigmented hidroacanthoma simplex resembled nonmelanoma skin cancer; pigmented hidroacanthoma simplex appeared like a seborrheic keratosis or a solar lentigo; EPs sensu stricto presented as pink nodules if nonpigmented and were similar to seborrheic keratosis if pigmented; dermal duct tumors appeared as pigmented nodular lesions.
CONCLUSIONS
Distinct dermoscopic features appeared to be recurrent in each histopathological variant. Dermoscopy can provide important clues for the diagnosis of EP; the final diagnosis is allowed by histopathology. To achieve a correct diagnosis of EP, because of its clinical and dermoscopic variability, surgical excision is recommended.
PubMed: 31723462
DOI: 10.5826/dpc.0904a07 -
Journal of the European Academy of... Oct 2016
Topics: Adult; Aged; Aged, 80 and over; Dermoscopy; Diagnosis, Differential; Female; Humans; Male; Poroma; Skin Neoplasms; Sweat Gland Diseases
PubMed: 26333195
DOI: 10.1111/jdv.13302 -
Journal of Cutaneous Pathology Feb 2014
Topics: Acrospiroma; Biopsy; Diagnosis, Differential; Eccrine Porocarcinoma; Female; Humans; Skin Neoplasms
PubMed: 24460880
DOI: 10.1111/cup.12291 -
Actas Dermo-sifiliograficas 2008
Topics: Acrospiroma; Adult; Diagnosis, Differential; Fingers; Humans; Male; Melanoma; Nevus, Pigmented; Skin Neoplasms; Skin Pigmentation; Sweat Gland Neoplasms
PubMed: 18558065
DOI: No ID Found -
Archives of Dermatology Jun 1976A 44-year-old woman had multiple papular lesions of 20 years' duration. The lesions were limited to the right lower extremity and were arranged in a linear fashion. They...
A 44-year-old woman had multiple papular lesions of 20 years' duration. The lesions were limited to the right lower extremity and were arranged in a linear fashion. They had the histologic appearance of eccrine poroma; however, thin intertwining strands of tumor cells extended down into the dermis in a pattern similar to that of premalignant fibroepithelioma. Also, bud-like proliferations of tumor cells were attached to the epidermis, analogous to those superficial basal cell epithelioma. A dilated cystic duct resembling that found in syringoma was present in the upper part of the dermis. To my knowledge, such a linear distribution of multiple eccrine poromas has not been reported in the dermatologic literature.
Topics: Adult; Female; Humans; Sweat Gland Neoplasms
PubMed: 942218
DOI: No ID Found -
International Journal of Dermatology May 1979
Topics: Aged; Humans; Male; Skin; Sweat Gland Neoplasms
PubMed: 457327
DOI: 10.1111/j.1365-4362.1979.tb01935.x -
International Journal of Surgery Case... 2020Eccrine poroma is a benign adnexal neoplasm originating from epidermal sweat ducts mainly affecting the palmoplantar skin, buttock as a location of origin of poroma has...
INTRODUCTION
Eccrine poroma is a benign adnexal neoplasm originating from epidermal sweat ducts mainly affecting the palmoplantar skin, buttock as a location of origin of poroma has rarely been reported, it is the first reported case of recurrent poroma in this site.
PRESENTATION OF CASE
We report an unusual case of eccrine poroma in the gluteal region of a 62 years old female associated with gluteal abscess, surgically excised with histologically clear margins, then recurred after one and half year with a given history of mild trauma.
DISCUSSION
Given the uncommonness of these neoplasms, there stays a general lack of data on pathogenesis, atypical presentation, atypical sites, recurrence and risk of malignant transformation into porocarcinoma.
CONCLUSION
Gluteal skin is an unusual location for a benign poroma. Early recognition and appropriate treatment at the initial presentation by complete resection with histopathology confirmation and follow-up are crucial to ruling out other diagnoses, such as lesions of malignant transformation.
PubMed: 32911185
DOI: 10.1016/j.ijscr.2020.08.042 -
The American Journal of Dermatopathology Aug 2023Cuticular poroma is a rare variant of poroma composed of exclusively or predominantly cuticular cells, namely of large cells with ample eosinophilic cytoplasm. We report...
Cuticular poroma is a rare variant of poroma composed of exclusively or predominantly cuticular cells, namely of large cells with ample eosinophilic cytoplasm. We report 7 cases of this rare tumor identified among 426 neoplasms diagnosed as poroma or porocarcinoma. The patients were 4 males and 3 females, ranging in age from 18 to 88 years. All presented with a solitary asymptomatic nodule. The location included knee (2 cases), shoulder, thigh, shin, lower arm, and neck (each 1). All lesions were surgically removed. No evidence of disease was observed in 5 patients with available follow-up (range 12-124 months).Microscopically, all neoplasms were composed of variably sized, focally closed packed, or interconnecting nodules constituted mostly of cuticular cells. Small poroid cells were a focal feature in 5 tumors, whereas in the remaining 2 cases, poroid cells with conspicuous but still in minority. Five neoplasms were somewhat asymmetric, with irregular outlines. Ductal differentiation and intracytoplasmic vacuoles were seen in 6 tumors. Other features variably encountered were conspicuous intranuclear pseudoinclusions, cystic change, occasional multinucleated cells, increased mitoses, and stromal desmoplasia. Four of the 5 tumors analyzed with next-generation sequencing yielded YAP1::NUTM1 fusions. In addition, various mutations, mostly of unknown significance were identified in one neoplasm.
Topics: Male; Female; Humans; Adolescent; Young Adult; Adult; Middle Aged; Aged; Aged, 80 and over; Poroma; Sweat Gland Neoplasms; Transcription Factors; Eccrine Porocarcinoma
PubMed: 37335840
DOI: 10.1097/DAD.0000000000002465 -
Indian Journal of Dermatology 2015Although divergent adnexal differentiations are occasionally seen in poroma, poroma with sebaceous differentiation is extremely rare. We present here the second case of...
Although divergent adnexal differentiations are occasionally seen in poroma, poroma with sebaceous differentiation is extremely rare. We present here the second case of dermoscopy on poroma with sebaceous differentiation. A 38-year-old Japanese female presented with a 2-year history of a slow-growing nodule on her left forearm. Dermoscopically, fine hairpin-like vessels, beige lobular structures were seen in the nodule. Many small yellow dots were scattered between beige lobular structures, giving orange-beige in color as a whole. On the basis of histopathologic findings, a diagnosis of poroma with sebaceous differentiation was made. Some sebaceous tumors are known to exhibit yellowish structures on dermoscopy. Tumors with sebaceous differentiation, as well as conventional sebaceous tumors, can show yellow structures on dermoscopy.
PubMed: 25657405
DOI: 10.4103/0019-5154.147807