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Contact Dermatitis Jan 1994
Topics: Administration, Oral; Dermatitis, Allergic Contact; Humans; Male; Middle Aged; Prednisone; Single-Blind Method
PubMed: 8156773
DOI: 10.1111/j.1600-0536.1994.tb00739.x -
Schweizerische Medizinische... Jan 1991We describe a patient with acute transverse myelitis as the first symptom of systemic lupus erythematosus who was successfully treated with cyclophosphamide and... (Review)
Review
We describe a patient with acute transverse myelitis as the first symptom of systemic lupus erythematosus who was successfully treated with cyclophosphamide and prednisone. The literature on transverse myelitis is reviewed and its clinical presentation, diagnosis, therapy and prognosis are discussed. A new therapeutic approach involving cyclophosphamide and prednisone is proposed.
Topics: Adult; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Lupus Erythematosus, Systemic; Myelitis, Transverse; Prednisone
PubMed: 1992504
DOI: No ID Found -
Clinical investigation of Duchenne muscular dystrophy. Interesting results in a trial of prednisone.Archives of Neurology Aug 1987We investigated the effect of high-dose prednisone therapy in 33 boys with Duchenne muscular dystrophy. The drug was given daily in doses of 1.5 mg/kg of body weight (to... (Comparative Study)
Comparative Study
We investigated the effect of high-dose prednisone therapy in 33 boys with Duchenne muscular dystrophy. The drug was given daily in doses of 1.5 mg/kg of body weight (to a maximum of 80 mg) for six months. Muscle strength, joint contractures, timed functional tests, functional ability, and pulmonary function were measured at the beginning and end of the treatment period. The trial was designed using natural history controls, and the power of the study was 0.80 to detect a slowing of 50% in the rate of progression. During the period of the trial, muscle strength, functional grades, timed functional tests, and pulmonary function improved. Contractures followed the expected natural history of the illness.
Topics: Adolescent; Child; Child, Preschool; Contracture; Drug Evaluation; Electromyography; Humans; Male; Muscles; Muscular Dystrophies; Prednisone; Research Design; Respiratory Function Tests; Time Factors
PubMed: 3632393
DOI: 10.1001/archneur.1987.00520200016010 -
Oral Surgery, Oral Medicine, and Oral... Apr 1985An objective evaluation of 55 patients with chronic vesiculoerosive oral diseases was made to compare the beneficial and adverse effects of prednisone treatment.... (Comparative Study)
Comparative Study
An objective evaluation of 55 patients with chronic vesiculoerosive oral diseases was made to compare the beneficial and adverse effects of prednisone treatment. Patients were divided into groups of high, intermediate, and low drug dosages, as well as short and long periods of administration. Prednisone benefited 49 patients in spite of the fact that 55% had some adverse side effects. The duration of prednisone administration appeared to have a larger impact on side effects than the daily amount given. The most common side effects were gastrointestinal disturbances, mood alterations, polyuria and insomnia. There were no significant changes in blood pressure, blood sugar level, weight, or white blood cell counts. This study confirmed that systemic prednisone is a useful and beneficial treatment modality for patients with chronic oral inflammatory diseases.
Topics: Adolescent; Adult; Aged; Female; Gingivitis, Necrotizing Ulcerative; Humans; Male; Middle Aged; Prednisone; Time Factors
PubMed: 3858773
DOI: 10.1016/0030-4220(85)90060-x -
Journal of the American Dental... Aug 1984Systemic glucocorticoids in the form of prednisone have been effective in reducing signs and symptoms in a variety of acute and chronic oral inflammatory diseases. In... (Comparative Study)
Comparative Study
Systemic glucocorticoids in the form of prednisone have been effective in reducing signs and symptoms in a variety of acute and chronic oral inflammatory diseases. In the 101 patients prospectively studied, the benefits from prednisone treatment far outweighed the adverse side effects, which occurred in 61 patients. However, none of the adverse side effects was severe enough to require cessation of the prednisone. The adverse effects, which could be minimized by reducing the dosage in most instances, were primarily related to treatment that persisted for more than two weeks. Fluid retention or bloating was the most common symptom, and insomnia was the chief side effect in those patients receiving short-term treatment (less than two weeks). Blood sugar, blood pressure, weight, and white blood cell counts were not meaningfully altered. Variables in patients' drug response and side effects precluded formulation of precise prednisone dosages that would allow predictive outcomes.
Topics: Adolescent; Adult; Aged; Blood Glucose; Blood Pressure; Body Fluids; Female; Humans; Male; Middle Aged; Mouth Diseases; Prednisone; Prospective Studies; Time Factors; Ulcer
PubMed: 6590608
DOI: 10.14219/jada.archive.1984.0349 -
European Journal of Pediatrics Feb 1981
Comparative Study
Alternate-day prednisone is more effective than intermittent prednisone in frequently relapsing nephrotic syndrome. A report of "Arbeitsgemeinschaft für Pädiatrische Nephrologie.
Topics: Adolescent; Child; Child, Preschool; Humans; Nephrotic Syndrome; Prednisone; Recurrence
PubMed: 7227377
DOI: 10.1007/BF00442096 -
Tijdschrift Voor Psychiatrie 2015Hashimoto encephalitis (he) is an auto-immune disease, with 40-50% of patients developing psychopathology. This could require targeted treatment. HE and prednison could...
Hashimoto encephalitis (he) is an auto-immune disease, with 40-50% of patients developing psychopathology. This could require targeted treatment. HE and prednison could both cloud the identification of a concurrent depressive disorder. We saw a 78-year-old woman with he and a severe depression, and treated her succesfully with ect.
Topics: Aged; Brain Diseases; Depressive Disorder; Electroconvulsive Therapy; Encephalitis; Female; Hashimoto Disease; Humans; Prednisone; Treatment Outcome
PubMed: 25904434
DOI: No ID Found -
Ostomy/wound Management Jun 2014The main goals of treating peristomal pyoderma gangrenosum (PPG) - ulcerations in the stomal area - are to decrease pain, increase pouch adherence, and decrease...
The main goals of treating peristomal pyoderma gangrenosum (PPG) - ulcerations in the stomal area - are to decrease pain, increase pouch adherence, and decrease pyoderma. The literature suggests a wide variety of approaches to achieve this goal, but few studies report outcomes on the use of topical steroids. The purpose of this case study is to describe the results of a protocol developed to meet the goals of care for patients with PPG. Three patients presenting with PPG lesions were instructed to crush a 1-mg prednisone tablet for mixing with an equal part of a hydrocolloid powder. The mix was applied directly on the PPG lesions, covered with a calcium alginate (or hydrofiber) primary dressing, and secured with a hydrocolloid secondary dressing. The pouching system then was applied over the hydrocolloid dressing. Three goals of treatment were met: pain dissipated (in as quickly as 1 week); pouch adherence improved (within 0 to 3 days); and closure/healing of the lesions occurred (within 3 to 5 weeks), recurring in only one case in which the patient had a peristomal hernia. No side effects were observed. Although this self-treatment provided satisfactory results, further study is needed to evaluate its effectiveness in a larger population and longer follow-up.
Topics: Administration, Topical; Aged; Aged, 80 and over; Female; Humans; Male; Prednisone; Pyoderma Gangrenosum; Surgical Stomas
PubMed: 24905357
DOI: No ID Found -
Archives of Dermatology Apr 1969
Topics: Allergens; Chromates; Eczema; Female; Humans; Hypersensitivity; Male; Potassium; Prednisone; Skin Tests
PubMed: 5769323
DOI: No ID Found -
Annals of Internal Medicine May 1975
Topics: Giant Cell Arteritis; Humans; Prednisone
PubMed: 1137268
DOI: 10.7326/0003-4819-82-5-714_1