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Echocardiography (Mount Kisco, N.Y.) Sep 2021Preexcitation cardiomyopathy is a rare cardiac anomaly but it can be life threatening. It may occur in type B preexcitation syndrome. A patients with this condition...
Preexcitation cardiomyopathy is a rare cardiac anomaly but it can be life threatening. It may occur in type B preexcitation syndrome. A patients with this condition typically has an enlarged left ventricle and reduced systolic function without tachycardia-associated cardiomyopathy. Echocardiography plays an important role in diagnosis in identifying this condition by revealing the "rebounce" movement of the inter-ventricular septum (IVS). We report echocardiographic findings of five pediatric patients with preexcitation cardiomyopathy. All of them had a radiofrequency catheter ablation (RFCA) and recovered during the follow-up.
Topics: Cardiomyopathies; Child; Echocardiography; Electrocardiography; Humans; Pre-Excitation Syndromes; Wolff-Parkinson-White Syndrome
PubMed: 34505316
DOI: 10.1111/echo.15181 -
Journal of Veterinary Cardiology : the... Aug 2019Preexcitation alternans and orthodromic atrioventricular reciprocating tachycardia were diagnosed in a 3-month-old Boxer. The images described here show how conventional...
Preexcitation alternans and orthodromic atrioventricular reciprocating tachycardia were diagnosed in a 3-month-old Boxer. The images described here show how conventional electrocardiographic techniques (12-lead surface electrocardiography, 24-hour Holter monitoring, and ladder diagram) can be interpreted to gain detailed information on presence of canine atrioventricular accessory pathways and their conduction properties.
Topics: Animals; Diagnosis, Differential; Dog Diseases; Dogs; Electrocardiography; Electrocardiography, Ambulatory; Female; Pedigree; Pre-Excitation Syndromes
PubMed: 31405550
DOI: 10.1016/j.jvc.2019.04.001 -
Pacing and Clinical Electrophysiology :... Sep 2016With ablation, the follow-up of preexcitation syndrome now is difficult to assess. The purpose was to collect data of children with a preexcitation syndrome studied on...
BACKGROUND
With ablation, the follow-up of preexcitation syndrome now is difficult to assess. The purpose was to collect data of children with a preexcitation syndrome studied on two separate occasions within a minimal interval of 1 year.
METHODS
This is a retrospective chart review of 47 children initially aged 12 ± 4 years, who underwent two or more invasive electrophysiological studies (EPS) within 1-25 years of one another (6.3 ± 4.8) for occurrence of symptoms or new evaluation.
RESULTS
Among initially symptomatic children (n = 25), four (19%) became asymptomatic and one presented life-threatening arrhythmia. Among asymptomatic children (n = 22), five became symptomatic (22.7%). Anterograde conduction disappeared in seven of 23 children with initially long accessory pathway-effective refractory period, but four of six had still induced atrioventricular reentrant tachycardia (AVRT). AVRT was induced at second EPS in three of 13 asymptomatic preexcitation syndrome with negative initial EPS. There were no spontaneous adverse events in the five children with criteria of malignancy at initial EPS; signs of malignancy disappeared in two. At multivariate analysis, AVRT at initial EPS was the only independent factor of symptomatic AVRT during follow-up. Absence of induced AVRT at initial EPS was the only factor of absence of symptoms and a negative study at the second EPS.
CONCLUSIONS
There were no significant changes of data in children after 6.3 ± 4.8 years of follow-up. Most children with spontaneous/inducible AVRTs at initial EPS had still inducible AVRT at second EPS. Induced AF conducted with high rate has a relatively low prognostic value for the prediction of adverse events.
Topics: Adolescent; Adult; Child; Child Health; Child, Preschool; Disease Progression; Electrocardiography; Female; Humans; Infant; Longitudinal Studies; Male; Pre-Excitation Syndromes; Symptom Assessment; Young Adult
PubMed: 27448170
DOI: 10.1111/pace.12922 -
Cardiac Electrophysiology Clinics Dec 2020
Topics: Electrocardiography; Humans; Pre-Excitation Syndromes; Precision Medicine
PubMed: 33162007
DOI: 10.1016/j.ccep.2020.09.001 -
Journal of Cardiovascular... Jul 2006
Topics: AMP-Activated Protein Kinases; Humans; Multienzyme Complexes; Mutation; Pre-Excitation Syndromes; Protein Kinases; Protein Serine-Threonine Kinases; Wolff-Parkinson-White Syndrome
PubMed: 16836668
DOI: 10.1111/j.1540-8167.2006.00474.x -
Developmental Period Medicine 2018Essentially, preexcitation syndrome is the presence of an accessory pathway in the heart, which can lead to serious consequences, ranging from atrioventricular reentrant...
INTRODUCTION
Essentially, preexcitation syndrome is the presence of an accessory pathway in the heart, which can lead to serious consequences, ranging from atrioventricular reentrant tachycardia to sudden cardiac death. Wolff-Parkinson-White syndrome is the most common preexcitation syndrome.
AIM OF THE STUDY
The aim of the study was to evaluate the clinical course of the disease, as well as the treatment of children and adolescents hospitalized in the Department of Pediatric Cardiology in the years 2008-2015.
MATERIALS AND METHODS
The study was carried out in 45 children (62 % male, 38% female; the mean age 11 years). During the study we analyzed 12-lead ECG, 24-hour Holter ECG, echocardiography and the cycloergometric exercise test. The results of treatment were also discussed.
RESULTS
Apart from the typical features of preexcitation, the most prevalent abnormality found in ECG was atrioventricular reentrant tachycardia. In 24-hour Holter ECG the most frequently detected disorders were premature ventricular beats and premature atrial contractions. Structural heart defects were detected in 8.9% of the children. The cycloergometric exercise test was positive in 8.9% of patients. The mean duration of symptoms before the diagnosis was 2.5 years. 25% of the patients were asymptomatic. 42.2% of the children needed antiarrhythmic therapy, while 44.4% had accessory pathways ablated.
CONCLUSIONS
The most common symptom of preexcitation in the study group were heart palpitations. The most frequent type of arrhythmia in children with preexcitation syndrome was orthodromic atrioventricular reentrant tachycardia. For the majority of older children ablation of the accessory pathway was a recommended form of treatment. In younger children the standard preventive pharmacological treatment was applied for 6 to 12 months.
Topics: Adolescent; Child; Child, Preschool; Electrocardiography; Female; Humans; Infant; Infant, Newborn; Male; Wolff-Parkinson-White Syndrome
PubMed: 30056397
DOI: 10.34763/devperiodmed.20182202.113122 -
Cardiac Electrophysiology Clinics Dec 2020Patients with the Wolff-Parkinson-White syndrome may experience benign and malignant arrhythmias, the most common being atrioventricular reentrant tachycardias. This... (Review)
Review
Patients with the Wolff-Parkinson-White syndrome may experience benign and malignant arrhythmias, the most common being atrioventricular reentrant tachycardias. This arrhythmia may degenerate into atrial fibrillation, which can be conducted over an accessory pathway capable of exceptionally fast conduction to the ventricles and degenerate into ventricular fibrillation, leading to sudden cardiac death. These life-threatening events generally affect symptomatic patients in their third or fourth decade. Although rare, ventricular fibrillation may be the first clinical manifestation in subjects who are asymptomatic or unaware of their conditions. Electrophysiologic study may be useful to identify subjects at high risk of sudden cardiac death.
Topics: Accessory Atrioventricular Bundle; Adult; Atrial Fibrillation; Death, Sudden, Cardiac; Humans; Middle Aged; Pre-Excitation Syndromes; Ventricular Fibrillation; Wolff-Parkinson-White Syndrome; Young Adult
PubMed: 33162000
DOI: 10.1016/j.ccep.2020.08.002 -
Europace : European Pacing,... Jan 2005This brief review discusses the interesting early history of the pre-excitation syndrome. In 1913 Cohn and Fraser published the first patient with a short P-R interval,... (Review)
Review
This brief review discusses the interesting early history of the pre-excitation syndrome. In 1913 Cohn and Fraser published the first patient with a short P-R interval, wide QRS complexes, and paroxysmal tachycardia. This was followed by other cases of pre-excitation syndrome, all of which were considered to be due to bundle branch blocks. In 1930 Wolff, Parkinson, and White reported 11 patients with the syndrome, which came to bear their name. Two years later, Holzmann and Scherf suggested bypass tracts as the most likely mechanism of pre-excitation syndrome. In 1942, Wood et al. documented the first accessory connection at autopsy. Despite these early studies supporting the bypass theory, the quest for alternative mechanisms continued until the 1970s when electrophysiological studies and surgical therapy confirmed accessory connections as the mechanism of pre-excitation syndrome.
Topics: History, 20th Century; History, 21st Century; Humans; Pre-Excitation Syndromes
PubMed: 15670964
DOI: 10.1016/j.eupc.2004.09.005 -
The American Journal of Cardiology Feb 2018A 37-year-old man came to the emergency department because of several days of intermittent chest pain. An electrocardiogram (ECG) showed sinus rhythm, left atrial and...
A 37-year-old man came to the emergency department because of several days of intermittent chest pain. An electrocardiogram (ECG) showed sinus rhythm, left atrial and left ventricular enlargement, and an early repolarization pattern. A second ECG recorded 10 minutes later was strikingly different, with ST-segment elevation and large upright T waves in the anterior precordial leads, interpreted as evidence of an ST-segment elevation myocardial infarction, and the cardiac catheterization team was activated. Closer inspection of the ECG, however, disclosed that the changes were because of intermittent ventricular pre-excitation of the Wolff-Parkinson-White type, and no electrocardiographic, echocardiographic, or serum markers of myocardial infarction were found.
Topics: Adult; Biomarkers; Chest Pain; Diagnosis, Differential; Echocardiography; Electrocardiography; Humans; Male; Pre-Excitation Syndromes
PubMed: 29191564
DOI: 10.1016/j.amjcard.2017.09.036 -
Journal of Electrocardiology Sep 2012The electrocardiographic diagnosis of intraventricular conduction disturbances may be hindered by the coexistence of ventricular preexcitation. In fact, the premature... (Review)
Review
The electrocardiographic diagnosis of intraventricular conduction disturbances may be hindered by the coexistence of ventricular preexcitation. In fact, the premature depolarization of ventricular myocardium through an accessory pathway tends to conceal any electrocardiographic manifestation of a bundle-branch block. However, there are several conditions favoring the diagnosis of bundle-branch block associated with ventricular preexcitation: intermittency of ventricular preexcitation and/or bundle-branch block, fast atrioventricular (AV) nodal impulse propagation, slow conduction over the accessory pathway or between its ventricular insertion site and the remaining myocardium, and presence of atrioventricular junctional ectopic beats exposing the intraventricular conduction disturbance. This article reexamines the available data on preexcitation in patients with intraventricular blocks and presents clinical examples to emphasize the importance of a thorough examination of the electrocardiogram to attain the correct diagnosis of this association.
Topics: Bundle-Branch Block; Electrocardiography; Heart Conduction System; Humans; Pre-Excitation Syndromes
PubMed: 22560599
DOI: 10.1016/j.jelectrocard.2012.04.002