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BJOG : An International Journal of... Dec 2018To estimate the intergenerational association in teenage pregnancy, and whether there is a coupling tendency between a mother and daughter in how their teen pregnancies...
OBJECTIVE
To estimate the intergenerational association in teenage pregnancy, and whether there is a coupling tendency between a mother and daughter in how their teen pregnancies end, such as a termination of pregnancy (TOP) versus a live birth.
DESIGN
Population-based cohort study.
SETTING
Ontario, Canada.
POPULATION
A total of 15 097 mothers and their 16 177 daughters.
METHODS
Generalised estimating equations generated adjusted odds ratios (aOR) of a daughter experiencing a teen pregnancy in relation to the number of teen pregnancies her mother had. Multinomial logistic regression estimated the odds that a teen pregnancy ended with TOP among both mother and daughter. All models were adjusted for maternal age and world region of origin, the daughter's socio-demographic characteristics and comorbidities, mother-daughter cohabitation, and neighbourhood-level teen pregnancy rate.
MAIN OUTCOME MEASURES
Teen pregnancy in the daughter, between ages 15 and 19 years, and also the nature of the daughter's teen pregnancy, categorised as (1) no teen pregnancy, (2) at least one teen pregnancy, all exclusively ending with a live birth, and (3) at least one teen pregnancy, with at least one teen pregnancy ending with a TOP.
RESULTS
The proportion of daughters having a teen pregnancy among those whose mother had zero, one, two, or at least three teen pregnancies was 16.3, 24.9, 33.5 and 36.3%, respectively. The aOR of a daughter having a teen pregnancy was 1.42 (95% CI 1.25-1.61) if her mother had one, 1.97 (95% CI 1.71-2.26) if she had two, and 2.17 (95% CI 1.84-2.56) if her mother had three or more teen pregnancies, relative to none. If a mother had at least one teen pregnancy ending with TOP, then her daughter had an aOR of 2.12 (95% CI 1.76-2.56) for having a teen pregnancy also ending with TOP; whereas, if a mother had at least one teen pregnancy, all ending with a live birth, then her daughter had an aOR of 1.73 (95% CI 1.46-2.05) for that same outcome.
CONCLUSION
There is a strong intergenerational occurrence of teenage pregnancy between a mother and daughter, including a coupling tendency in how the pregnancy ends.
TWEETABLE ABSTRACT
Strong intergenerational association for teenage pregnancy between mother and daughter.
Topics: Abortion, Induced; Adolescent; Female; Gravidity; Humans; Live Birth; Mothers; Nuclear Family; Odds Ratio; Parity; Pregnancy; Pregnancy in Adolescence; Young Adult
PubMed: 29786971
DOI: 10.1111/1471-0528.15297 -
Blood Advances Feb 2024Advancements in orally bioavailable iron chelators and MRI methods have improved life expectancy and reproductive potential in thalassemia major (TM) and thalassemia... (Meta-Analysis)
Meta-Analysis
Advancements in orally bioavailable iron chelators and MRI methods have improved life expectancy and reproductive potential in thalassemia major (TM) and thalassemia intermedia (TI). Pregnancy is associated with adverse maternal and neonatal outcomes, frequency of which has not been well delineated. This systematic review aims to provide risk estimates of maternal and fetal outcomes in TM and TI and explore pregnancy's impact on iron homeostasis. Fifteen studies (429 participants, 684 pregnancies) were included. Meta-analysis revealed a higher thrombosis risk in TI (3.7%) compared to TM (0.92%), unchanged from prepregnancy. Heart failure risks in the earlier years appeared similar (TM 1.6% vs TI 1.1%), and maternal mortality in TM was 3.7%, but with current management, these risks are rare. Gestational diabetes and pre-eclampsia occurred in 3.9% and 11.3% of TM pregnancies, respectively. Caesarean section rates were 83.9% in TM and 67% in TI. No significant difference in stillbirth, small for gestational age neonates, or preterm birth incidence between TM and TI was observed. In TM pregnancies, red cell requirements significantly increased (from 102 to 139 ml/kg/year, P = 0.001), and 70% of TI pregnancies required blood transfusions. As expected, increased transfusion alongside chelation cessation led to a significant increase in serum ferritin during pregnancy (TM by 1005 ng/mL; TI by 332 ng/mL, P < 0.0001). Deterioration in iron status was further reflected by an increase in liver iron concentration (from 4.6 to 11.9 mg/g dry weight, P < 0.0001), and myocardial T2-star (T2∗) magnetic resonance imaging decreased (from 36.2 ± 2.5 ms to 31.1 ms) during pregnancy. These findings emphasize the elevated maternal risk of iron-related cardiomyopathy during pregnancy and labor, stressing the importance of cardiac monitoring and postpartum chelation therapy resumption.
Topics: Humans; Infant, Newborn; Pregnancy; Female; beta-Thalassemia; Iron; Pregnancy Outcome; Cesarean Section; Premature Birth
PubMed: 38181780
DOI: 10.1182/bloodadvances.2023011636 -
British Journal of Obstetrics and... Jul 1978A series of 14 triplet pregnancies has been analyzed. The older triplet mother had a better chance of fetal survival than the younger mother. Parity did not appear to...
A series of 14 triplet pregnancies has been analyzed. The older triplet mother had a better chance of fetal survival than the younger mother. Parity did not appear to have much effect on fetal survival but the maturity of the infants at birth had more influence than did birth weight, on their survival. The interval between the delivery of the second and third infants did not correlate with the poor prognosis for the last infant. Spontaneous breech delivery appeared to have a worse prognosis than assisted breech delivery. There was a high incidence of girls and they appeared to do better than the boys. There was a high incidence of monozygotic twin pairs in these triplet pregnancies.
Topics: Birth Order; Birth Weight; Delivery, Obstetric; Female; Fetal Death; Gestational Age; Humans; Labor Presentation; Maternal Age; Parity; Pregnancy; Pregnancy, Multiple; Triplets
PubMed: 678485
DOI: 10.1111/j.1471-0528.1978.tb15623.x -
Harefuah Feb 2003Teenage pregnancies are frequently unplanned, the young pregnant woman being often unmarried. These pregnancies occasionally end in induced abortion. Teenage pregnancy,... (Review)
Review
PROBLEM
Teenage pregnancies are frequently unplanned, the young pregnant woman being often unmarried. These pregnancies occasionally end in induced abortion. Teenage pregnancy, especially when unintended, is correlated with negative effects for the child and the mother. Despite the need to reduce the magnitude of this phenomenon, there is no reliable database on teenage pregnancy. Such a database could help define populations at risk, and could help in designing prevention programs. Birth rates, fetal deaths, and induced abortion are reported, but there is no uniformity or merging of the data.
OBJECTIVES
The aims of the paper are to present a methodology for the estimation of pregnancy rates and to use it for the analysis of characteristics and trends in adolescent pregnancies in Israel.
METHODS
The pregnancy rate was calculated as the sum of three outcomes: live birth, induced abortion, and fetal loss, at all stages of pregnancy.
RESULTS
Based on these computations, the teenage pregnancy rate in Israel was estimated as 32 per 1,000 adolescent girls. This rate was three times higher among Moslems as compared to Jews. From 1988 through 1998, the rate decreased by 12%. The pregnancy rate in Israel is similar to the rate of most Western-European countries, and is three times lower than the US rate.
CONCLUSION
There is a need to improve the means for collecting the data on which the computations are based, to build an algorithm specifically adapted to Israel, and to publish detailed pregnancy rates on a regular basis.
Topics: Adolescent; Female; Humans; Israel; Pregnancy; Pregnancy in Adolescence
PubMed: 12653047
DOI: No ID Found -
Soins. Pediatrie, Puericulture 2016Adolescence and pregnancy are two periods which involve major psychological and identity changes. Teenage pregnancies are often considered to be a result of a confusion...
Adolescence and pregnancy are two periods which involve major psychological and identity changes. Teenage pregnancies are often considered to be a result of a confusion between these periods. The circumstances of teenage pregnancies and early motherhood are diverse and sit within the wider context of the psychopathology of adolescence, the heterogeneity of family configurations and evolutions in society.
Topics: Adolescent; Female; Humans; Mother-Child Relations; Pregnancy; Pregnancy in Adolescence; Pregnancy, Unplanned
PubMed: 27444529
DOI: 10.1016/j.spp.2016.05.003 -
Narrative Inquiry in Bioethics 2020Uterine factor infertility (UFI) affects 1-5% of women of reproductive age, and uterus transplantation is the only option available to these women for carrying a...
Uterine factor infertility (UFI) affects 1-5% of women of reproductive age, and uterus transplantation is the only option available to these women for carrying a pregnancy. The ethical analysis of uterus transplantation focuses on the value and experience of pregnancy in recipients; to date, however, no personal experiences with pregnancy after uterus transplantation have been published. The authors share the stories of two of our uterus transplant recipients, obtained through semi-structured, in-person interviews. The interview questions focused on the recipients' experiences during pregnancy. We report the cases as the interwoven narratives of the two women's pregnancies and their perceptions of the value of gestation.
Topics: Ethical Analysis; Female; Humans; Narration; Pregnancy; Transplant Recipients; Uterus
PubMed: 33583857
DOI: 10.1353/nib.2020.0074 -
BMJ (Clinical Research Ed.) Feb 1994
Topics: Cause of Death; Developing Countries; Female; Humans; Maternal Health Services; Maternal Mortality; Maternal Welfare; Pregnancy; Pregnancy Complications; Women's Health
PubMed: 8124139
DOI: 10.1136/bmj.308.6925.353 -
The Journal of Maternal-fetal &... Sep 2013The aim of this report was to evaluate and present the fourth longest delay among twin and multiple pregnancies described in the literature. (Review)
Review
A twin pregnancy provided with ICSI, an abortion of the first fetus at the 18th week and live birth of the second fetus at the end of the 36th week: a case report and literature review.
OBJECTIVE
The aim of this report was to evaluate and present the fourth longest delay among twin and multiple pregnancies described in the literature.
METHODS
How can we optimize the health of the remaining fetus or fetuses after spontaneous abortion of the first fetus in multiple pregnancies? By considering one of our cases, we try to answer that question in light of the published literature.
RESULTS
In our case, the second fetus was born at the end of the 36th week after abortion of the first fetus at the beginning of the 18th week. Delayed interval delivery was postponed 132 gestational days.
CONCLUSIONS
The implementation of delayed intentional delivery is a reliable and required approach especially for infertility patients when they are selected carefully and monitored closely.
Topics: Abortion, Spontaneous; Adult; Breech Presentation; Cesarean Section; Female; Humans; Infant, Newborn; Live Birth; Male; Pregnancy; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Pregnancy, Twin; Sperm Injections, Intracytoplasmic
PubMed: 23488587
DOI: 10.3109/14767058.2013.784253 -
Lupus 2001The antiphospholipid antibodies (aPLs) are a diverse group of autoantibodies associated with a pattern of disease known as antiphospholipid syndrome (APS). Pregnancy... (Review)
Review
The antiphospholipid antibodies (aPLs) are a diverse group of autoantibodies associated with a pattern of disease known as antiphospholipid syndrome (APS). Pregnancy complications secondary to placental insufficiency are key features of this disease. The mechanisms underlying the placental pathology remain unclear. In this article the process of placentation in healthy and pathological pregnancies is reviewed. The evidence for defective placentation in APS pregnancies and involvement of aPLs in this process is summarized. Finally hypotheses based on the interpretation of these studies are discussed.
Topics: Antiphospholipid Syndrome; Female; Humans; Placentation; Pregnancy; Pregnancy Complications
PubMed: 11237128
DOI: 10.1191/096120301667486047 -
Reproductive Health Sep 2022Ineffective or no use of contraception following an unintended pregnancy contributes to a subsequent unintended pregnancy. This study aimed to determine whether women's...
BACKGROUND
Ineffective or no use of contraception following an unintended pregnancy contributes to a subsequent unintended pregnancy. This study aimed to determine whether women's experiences of unintended pregnancies affect changing their contraceptive using patterns.
METHODS
We analysed the 2017/2018 Bangladesh Demographic and Health Survey data. The contraceptive switching pattern was computed by comparing women's contraceptives using data before and after pregnancy. Women were categorised into the following three groups, depending on their patterns of contraceptive use before and after pregnancy: no change, if there were no change in contraceptive using pattern; switched to higher effective contraceptives, if changed from pre-pregnancy less effective contraceptives to post-pregnancy more effective contraceptives; switched to less effective contraceptives, if changed from pre-pregnancy more effective contraceptives to post-pregnancy less effective contraceptives. Women's intention in the most recent pregnancy was our primary explanatory variable, classified as wanted, mistimed and unwanted. Multinomial multilevel logistics regression was used to determine the association between women's intention in the most recent pregnancy and women's contraceptive methods switching patterns from before to after pregnancy.
RESULTS
Around 20% of the most recent pregnancies that ended with a live birth were unintended at conception. No contraceptive use was reported by 37% of women before their pregnancies which decreased to 24% after pregnancies. Overall, around 54% of women who reported no contraceptive use before pregnancy used modern contraceptives after pregnancy. The rate was higher among women who experienced unwanted pregnancy (73.4%) than mistimed (58.8%) and wanted (53.4%) pregnancy. Experience of mistimed pregnancy was associated with a higher likelihood of no contraceptive change (aOR, 1.84, 95% CI 1.41-2.39) and switching to less effective contraceptives (aOR, 1.58, 95% CI 1.10-2.26) than switching to more effective contraceptives. However, unwanted pregnancy was not associated with any significant change in contraceptives use from before to after pregnancy.
CONCLUSION
Experience of unintended pregnancy did not change women's contraception using patterns, which indicates the risk of repeat unintended pregnancies and associated adverse consequences, including maternal and child morbidity and mortality. Policies to ensure access to and use of modern contraceptives among women facing unwanted or mistimed pregnancies are recommended.
Topics: Contraception; Contraception Behavior; Contraceptive Agents; Female; Humans; Pregnancy; Pregnancy, Unplanned; Pregnancy, Unwanted
PubMed: 36050768
DOI: 10.1186/s12978-022-01492-w