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Rheumatology International Mar 2007The aim of our study was to assess the prevalence and outcome of pregnancy in idiopathic inflammatory myopathy patients who became pregnant after the onset of the...
The aim of our study was to assess the prevalence and outcome of pregnancy in idiopathic inflammatory myopathy patients who became pregnant after the onset of the disease. Female idiopathic inflammatory myopathy patients (173) were included in our study. The patients' charts and clinical data were retrospectively analyzed. One hundred and four female idiopathic inflammatory myopathy patients had 186 pregnancies, but only nine of these patients (4 polymyositis-PM, 5 dermatomyositis-DM) became pregnant after the onset of the disease. Nine patients with pregnancies after the disease onset had 14 gravidities. Six pregnancies resulted in normal deliveries, two ended in prematurity, six ended in abortions (two induced abortions). Regarding the four patients (3 PM, 1 DM) with active disease at the time of pregnancy, two pregnancies ended in prematurity, four ended in spontaneous abortion and one healthy baby delivered. The other five patients (2 PM, 3 DM) with the disease in remission had uneventful pregnancies and healthy babies were delivered. Treatment was not required during pregnancy in case of two dermatomyositis patients with long lasting remission. New onset dermatomyositis developed in one patient in her pregnancy's third trimester. The mean weight of newborns in the active myositis cases was 2,193 (1,680-2,700) g; while in patients with remission was 3,167 (2,800-3,800) g. The active maternal disease in idiopathic inflammatory myopathy (IIM) might result intrauterin retardation and death. Disease activity in active and new-onset cases could be controlled by increasing the dose of corticosteroid.
Topics: Abortion, Spontaneous; Adult; Anti-Inflammatory Agents; Dermatomyositis; Female; Humans; Live Birth; Methylprednisolone; Polymyositis; Pregnancy; Pregnancy Complications; Premature Birth; Retrospective Studies
PubMed: 17033833
DOI: 10.1007/s00296-006-0239-8 -
Soins. Gynecologie, Obstetrique,... Oct 1991
Topics: Adolescent; Contraception; Female; Humans; Incest; Pregnancy; Pregnancy in Adolescence; Sex Education
PubMed: 1962262
DOI: No ID Found -
Hypertension in Pregnancy 2022Increased intraabdominal pressure (IAP) can result in compression of the abdominal-pelvic venous system leading to signs and symptoms of end organ dysfunction. It has...
Increased intraabdominal pressure (IAP) can result in compression of the abdominal-pelvic venous system leading to signs and symptoms of end organ dysfunction. It has been hypothesized as a pathophysiologic process of preeclampsia. We aim to evaluate the role of IAP in normotensive vs preeclamptic, and singleton vs twin pregnancies. We hypothesized that IAP would be higher in preeclamptics and twins.Women undergoing scheduled cesarean delivery were enrolled in four groups: Singletons- Preeclamptic and Normotensive, Twins- Preeclamptic and Normotensive. Elevated IAP was seen in singleton pregnancies with preeclampsia, representing a pathologic process; and in all twin pregnancies, suggesting a physiologic process.
Topics: Pregnancy; Female; Humans; Pre-Eclampsia; Pregnancy Outcome; Pregnancy, Twin; Twins; Cesarean Section
PubMed: 35669998
DOI: 10.1080/10641955.2022.2085741 -
The Cochrane Database of Systematic... Dec 2011Twin pregnancies are associated with increased perinatal mortality, mainly related to prematurity, but complications during birth may contribute to perinatal loss or... (Review)
Review
BACKGROUND
Twin pregnancies are associated with increased perinatal mortality, mainly related to prematurity, but complications during birth may contribute to perinatal loss or morbidity. The option of planned caesarean section to avoid such complications must therefore be considered. On the other hand, randomised trials of other clinical interventions in the birth process to avoid problems related to labour and birth (planned caesarean section for breech, and continuous electronic fetal heart rate monitoring), have shown an unexpected discordance between short-term perinatal morbidity and long-term neurological outcome. The risks of caesarean section for the mother in the current and subsequent pregnancies must also be taken into account.
OBJECTIVES
To determine the short- and long-term effects on mothers and their babies, of planned caesarean section for twin pregnancy.
SEARCH METHODS
We searched the Cochrane Pregnancy and Childbirth Group's Trials Register (30 September 2011).
SELECTION CRITERIA
Randomised trials comparing a policy of caesarean section with planned vaginal birth for women with twin pregnancy.
DATA COLLECTION AND ANALYSIS
Two researchers independently assessed eligibility, quality and extracted data. Data were checked for accuracy.
MAIN RESULTS
One small trial with unconfirmed allocation concealment compared caesarean section with planned vaginal birth in 60 women with vertex/non-vertex twin pregnancies. There were no differences in perinatal outcome. The trial was too small to exclude the possibility of clinically meaningful benefits of either approach. There is one additional trial currently ongoing.
AUTHORS' CONCLUSIONS
There is a lack of robust evidence to guide clinical advice regarding the method of birth for twin pregnancies. Women should be informed of possible benefits and risks of either approach, including short-term and long-term consequences for both mother and babies. Future research should aim to provide unbiased evidence, including long-term outcomes.
Topics: Cesarean Section; Female; Humans; Pregnancy; Pregnancy Outcome; Pregnancy, Twin
PubMed: 22161406
DOI: 10.1002/14651858.CD006553.pub2 -
Best Practice & Research. Clinical... Mar 2022Medically-indicated deliveries are common in twin pregnancies given the increased risk of various obstetric complications in twin compared to singleton pregnancies,... (Review)
Review
Medically-indicated deliveries are common in twin pregnancies given the increased risk of various obstetric complications in twin compared to singleton pregnancies, mainly hypertensive disorders of pregnancy and foetal growth restriction. Due to the unique characteristics of twin pregnancies, the success rates and safety of labour induction may be different than in singleton pregnancies. However, while there are abundant data regarding induction of labour in singleton pregnancies, the efficacy and safety of labour induction in twin pregnancies have been far less studied. In the current manuscript we summarize available data on various aspects of labour induction in twin pregnancies including incidence, success rate, prognostic factors, safety and methods for labour induction in twins. This information may assist healthcare providers in counselling patients with twin pregnancies when labour induction is indicated.
Topics: Female; Fetal Growth Retardation; Humans; Labor, Induced; Labor, Obstetric; Pregnancy; Pregnancy Outcome; Pregnancy, Twin; Twins
PubMed: 34844886
DOI: 10.1016/j.bpobgyn.2021.10.001 -
Adolescent Medicine: State of the Art... Aug 2015Because 83% of adolescent pregnancies among teens 15 to 19 years old are unintended and because adolescents with chronic medical conditions are as likely to be sexually... (Review)
Review
Because 83% of adolescent pregnancies among teens 15 to 19 years old are unintended and because adolescents with chronic medical conditions are as likely to be sexually involved as are healthy teens, preventing unintended pregnancies among teens with chronic endocrine conditions, including diabetes mellitus (both types 1 and 2), PCOS, and thyroid dysfunction, is critically important. Evidence-based guidelines are available to assist with assessment of the risks versus the benefits of specific options for contraception in teens with these and other medical conditions. In many teens, including those with chronic medical conditions, the top-tier contraceptive methods--implants and intrauterine devices--represent the most effective, safest, and most successful contraceptive options for adolescents. Prepregnancy counseling can be an important tool for managing chronic endocrine conditions and lowering the risks for both mother and fetus, but it is underutilized among all women, particularly adolescents. The management of pregnancies complicated by DM, PCOS, and thyroid conditions is facilitated by a coordinated effort among obstetricians, endocrinologists, dietitians, and nurse educators. Primary physicians should be aware of their potential role in preventing unplanned pregnancies among all adolescents, but particularly among those with chronic medical conditions.
Topics: Adolescent; Contraception; Endocrine System Diseases; Female; Humans; Pregnancy; Pregnancy in Adolescence; Pregnancy, Unplanned
PubMed: 26999878
DOI: No ID Found -
Chinese Medical Journal Jun 2020
Topics: Female; Gestational Age; Humans; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Pregnancy, Twin
PubMed: 32345825
DOI: 10.1097/CM9.0000000000000808 -
British Medical Journal Mar 1980
Topics: Abortion, Spontaneous; Birth Order; Female; Fetal Death; Humans; Parity; Pregnancy; Risk
PubMed: 7363031
DOI: 10.1136/bmj.280.6215.715-b -
International Journal of Rheumatic... Nov 2014To evaluates the pregnancy outcomes in systemic lupus erythematosus (SLE) patients in South Korea and determine the predictive factors for adverse fetal and maternal...
OBJECTIVES
To evaluates the pregnancy outcomes in systemic lupus erythematosus (SLE) patients in South Korea and determine the predictive factors for adverse fetal and maternal outcomes.
METHODS
All pregnancies in SLE patients who were seen at the Samsung Medical Center between November 1994 and December 2010 were included and retrospectively analyzed. SLE flares were determined by the Lupus Activity Index-Pregnancy (LAI-P) score.
RESULTS
Sixty-two pregnancies were observed in 50 patients. Fifty-one (82.3%) live births and 11 (17.7%) fetal losses were observed. Thirty-eight of the live births (74.5%) were full-term and 13 (25.5%) were preterm births. Fetal losses included three spontaneous abortions, two stillbirths and six therapeutic abortions. Proteinuria during pregnancy was a predictive factor for adverse fetal outcomes (adjusted odds ratio [OR] 12.50; P = 0.032). An LAI-P score was obtained in 36 pregnancies, and SLE flares occurred in 12 pregnancies (33.3%), primarily during the second trimester (46.2%). Renal involvement (69.2%) was the most common SLE flare during pregnancy. All flares were classified as severe flare according to LAI-P scores. SLE flares during pregnancy were strongly affected by proteinuria prior to pregnancy (adjusted OR 30.28; P = 0.024) and the presence of antiphospholipid antibodies (adjusted OR 6.62; P = 0.047).
CONCLUSION
Our study demonstrated a rate of live births and of flares in pregnant lupus patients comparable to recent reports in Western countries. Proteinuria during and prior to pregnancy and presence of antiphospholipid antibodies were predictive factors for poor pregnancy outcome. Preserved renal function prior to pregnancy resulted in favorable outcomes even in patients with a history of lupus nephritis.
Topics: Abortion, Spontaneous; Adult; Female; Humans; Live Birth; Lupus Erythematosus, Systemic; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Republic of Korea; Retrospective Studies; Stillbirth; Young Adult
PubMed: 25267089
DOI: 10.1111/1756-185X.12435 -
Clinical Obstetrics and Gynecology Sep 2015
Topics: Female; Humans; Pregnancy; Pregnancy, High-Risk; Pregnancy, Multiple; Reproductive Techniques, Assisted
PubMed: 26230173
DOI: 10.1097/GRF.0000000000000139