-
Food and Chemical Toxicology : An... Jul 2024
Review
Topics: Humans; Perfume; Animals; Risk Assessment; Odorants; 1-Propanol; Endpoint Determination; Toxicity Tests; Databases, Chemical; Consumer Product Safety
PubMed: 38697502
DOI: 10.1016/j.fct.2024.114697 -
ACS Sensors Jan 2023As an important biomarker of lung cancer, -propanol at the sub-ppm level is still challenging to be detected for a simple and immediate early diagnosis. In this work, a...
As an important biomarker of lung cancer, -propanol at the sub-ppm level is still challenging to be detected for a simple and immediate early diagnosis. In this work, a new -propanol gas sensor with an ultralow detection limit down to 100 ppb is presented using AgCrO nanoparticles synthesized by a simple hydrothermal method. Compared with the congeneric CuCrO and commercial SnO, AgCrO exhibits prevailing performances, including a higher selectivity, dynamic response, and logarithmical linearity but lower working temperature. The first-principles calculation and the energy band theoretical analysis are combined to elucidate the sensing mechanism, in which the chemical adsorption of gaseous molecules to silver followed by the dehydrogenation on chromium on the surface of AgCrO is responsible for the outstanding susceptibility toward -propanol. The proposed metal oxide semiconductor gas sensor capable of sub-ppm -propanol detection provides a route to design and optimize the sensitive material system for the advanced trace detection of the volatile organic compounds.
Topics: 1-Propanol; Propanols; Nanoparticles; Adsorption; Chromium; Gases
PubMed: 36584336
DOI: 10.1021/acssensors.2c02182 -
Lancet (London, England) Jul 1995
Topics: 1-Propanol; Bloodletting; Disinfection; Humans; Hygiene
PubMed: 7616833
DOI: 10.1016/s0140-6736(95)91307-6 -
The Journal of Organic Chemistry Mar 1949
Topics: 1-Propanol; Propanolamines; Propanols
PubMed: 18117733
DOI: 10.1021/jo01154a018 -
World Journal of Microbiology &... Oct 2019Odd-chain fatty acids (OCFAs) have been reported to possess pharmacological activity and have been used in the manufacture of agricultural and industrial chemicals. We...
Odd-chain fatty acids (OCFAs) have been reported to possess pharmacological activity and have been used in the manufacture of agricultural and industrial chemicals. We here provided a new method to increase the OCFAs content in oil produced by Rhodococcus opacus PD630 through addition of 1-propanol to the fermentation media. The OCFAs in oil of R. opacus PD630 are primarily pentadecanoic acid (C15:0), heptadecanoic acid (C17:0) and heptadecenoic acid (C17:1). After adding 0.5-1.5% (v/v) 1-propanol, the production of oil increased from 1.27 g/L to 1.31-1.61 g/L, and the OCFAs content in oil increased by 46.7-55.1%. Metabolic intermediates determination and transcriptome analysis revealed that R. opacus assimilated 1-propanol through methylmalonyl-CoA pathway. When the nitrogen source was limited, propionyl-CoA was converted to propionyl-acyl carrier protein (ACP) which could be used as primer during the elongation of fatty acid synthesis. Then OCFAs were produced when odd number of propionyl-ACP was incorporated in the cycles of fatty acid synthesis.
Topics: 1-Propanol; Acyl Coenzyme A; Alcohols; Biomass; Fatty Acids; Fatty Acids, Monounsaturated; Fermentation; Metabolic Networks and Pathways; Rhodococcus; Transcriptome
PubMed: 31637528
DOI: 10.1007/s11274-019-2748-0 -
International Journal of Molecular... Jun 2023Vapor pressures and other thermodynamic properties of liquids, such as density and enthalpy of mixtures, are the key parameters in chemical engineering for designing new...
Vapor pressures and other thermodynamic properties of liquids, such as density and enthalpy of mixtures, are the key parameters in chemical engineering for designing new process units, and are also essential for understanding the physical chemistry, macroscopic and molecular behavior of fluid systems. In this work, vapor pressures between 278.15 and 323.15 K, densities and enthalpies of mixtures between 288.15 and 318.15 K for the binary mixture (2-propanol + 1,8-cineole) have been measured. From the vapor pressure data, activity coefficients and excess Gibbs energies were calculated via the Barker's method and the Wilson equation. Excess molar volumes and excess molar enthalpies were also obtained from the density and calorimetric measurements. Thermodynamic consistency test between excess molar Gibbs energies and excess molar enthalpies has been carried out using the Gibbs-Helmholtz equation. Robinson-Mathias, and Peng-Robinson-Stryjek-Vera together with volume translation of Peneloux equations of state (EoS) are considered, as well as the statistical associating fluid theory that offers a molecular vision quite suitable for systems having highly non-spherical or associated molecules. Of these three models, the first two fit the experimental vapor pressure results quite adequately; in contrast, only the last one approaches the volumetric behavior of the system. A brief comparison of the thermodynamic excess molar functions for binary mixtures of short-chain alcohol + 1,8-cineole (cyclic ether), or +di-n-propylether (lineal ether) is also included.
Topics: Eucalyptol; 2-Propanol; 1-Propanol; Thermodynamics; Gases; Propanols
PubMed: 37373528
DOI: 10.3390/ijms241210380 -
International Journal of Molecular... Jun 2023Ionic liquids (ILs) have presented excellent behaviors in the separation of azeotropes in extractive distillation. However, the intrinsic molecular nature of ILs in the...
Ionic liquids (ILs) have presented excellent behaviors in the separation of azeotropes in extractive distillation. However, the intrinsic molecular nature of ILs in the separation of azeotropic systems is not clear. In this paper, Fourier-transform infrared spectroscopy (FTIR) and theoretical calculations were applied to screen the microstructures of ethyl propionate-n-propanol-1-ethyl-3-methylimidzolium acetate ([EMIM][OAC]) systems before and after azeotropy breaking. A detailed vibrational analysis was carried out on the (C=O) region of ethyl propionate and (O-D) region of n-propanol-. Different species, including multiple sizes of propanol and ethyl propionate self-aggregators, ethyl propionate-n-propanol interaction complexes, and different IL-n-propanol interaction complexes, were identified using excess spectroscopy and confirmed with theoretical calculations. Their changes in relative amounts were also observed. The hydrogen bond between n-propanol and ethyl propionate/[EMIM][OAC] was detected, and the interaction properties were also revealed. Overall, the intrinsic molecular nature of the azeotropy breaking was clear. First, the interactions between [EMIM][OAC] and n-propanol were stronger than those between [EMIM][OAC] and ethyl propionate, which influenced the relative volatilities of the two components in the system. Second, the interactions between n-propanol and [EMIM][OAC] were stronger than those between n-propanol and ethyl propionate. Hence, adding [EMIM][OAC] could break apart the ethyl propionate-n-propanol complex (causing the azeotropy in the studied system). When ([EMIM][OAC]) was lower than 0.04, the azeotropy still existed mainly because the low IL could not destroy the whole ethyl propionate-n-propanol interaction complex. At (IL) > 0.04, the whole ethyl propionate-n-propanol complex was destroyed, and the azeotropy disappeared.
Topics: Ionic Liquids; 1-Propanol; Spectroscopy, Fourier Transform Infrared; Propanols
PubMed: 37445775
DOI: 10.3390/ijms241310597 -
The New England Journal of Medicine Jan 1994
Topics: 1-Propanol; Adult; Alcoholic Intoxication; Baths; Child; Fever; Humans
PubMed: 8264758
DOI: 10.1056/NEJM199401203300319 -
Electrophoresis Sep 20191-propanol is a primary alcohol extensively used in the pharmaceutical, chemical, and food industries. It has been also found as a contaminant in the atmosphere and is...
1-propanol is a primary alcohol extensively used in the pharmaceutical, chemical, and food industries. It has been also found as a contaminant in the atmosphere and is considered a model compound to mimic the behavior and fate of aliphatic alcohols exposed to environmental conditions. In order to understand that role of relevant variables, this paper presents results obtained with a simple experimental set-up to investigate the reactivity of 1-propanol under mild oxidizing conditions. Coupling this system with CE-C D allowed the quantification of the carboxylic acids formed. For the described experiments, aqueous solutions of 1-propanol were placed inside a photoreactor and oxidized upon the addition of TiO and/or H O . According to the described results, the addition of H O (0.1% w/w) was the most significant variable, roughly tripled the amount of carboxylic acids generated and led to the conversion of up to 70% of the initially available 1-propanol (1 mmol/L). More importantly, the reaction yielded the formation (within 10 min) of propionate (50 µmol/L), acetate (400 µmol/L), formate (50 µmol/L), and malonate (200 µmol/L). The latter is critically important because it represents the first example of the photochemical oxidation of both terminal carbons of the C -chain of 1-propanol under mild conditions, and opens new avenues for the production of this important chemical building block.
Topics: 1-Propanol; Electric Conductivity; Electrophoresis, Capillary; Hydrogen Peroxide; Malonates; Oxidation-Reduction; Photolysis; Ultraviolet Rays
PubMed: 30793781
DOI: 10.1002/elps.201900001 -
BMC Cancer Jan 2023Ultrasmall superparamagnetic iron oxide (USPIO) nanoparticles are of potential magnetic resonance imaging (MRI) contrast agents for tumor diagnosis. However, ultrasmall...
BACKGROUND
Ultrasmall superparamagnetic iron oxide (USPIO) nanoparticles are of potential magnetic resonance imaging (MRI) contrast agents for tumor diagnosis. However, ultrasmall particle size or negative surface charge lead to relative short half-life which limit the utilization of USPIO for in vivo MRI contrast agents.
METHODS
Superparamagnetic FeO nanoparticles coated with polyacrylic acid (PAA)were synthetized, and modified by 3-amino propanol and 3-diethyl amino propyl amine. The characteristics of superparamagnetic FeO nanoparticles were investigated through transmission electron microscopy, X-ray diffraction analysis, Zata potential analysis, thermogravimetric analysis, and relaxation properties analysis. Magnetic resonance imaging animal experiment was performed.
RESULTS
The synthetized nanoparticles were irregular spherical, with small particle size, few agglomeration, and good dispersion in water. After modification, the potential fluctuation of nanoparticles was small, and the isoelectric point of nanoparticles changed to high pH. After 3-amino propanol modification, the weight loss of the curve from 820 to 940 °C was attributed to the decomposition of 3-amino propanol molecules on the surface. The T1 relaxation rate of nanoparticles changed little before and after modification, which proved that the modification didn't change the relaxation time. Brighter vascular images were observed after 3-amino propanol modification through measurement of magnetic resonance tumor imaging.
CONCLUSION
These data indicated the FeO nanoparticles modified by 3-amino propanol should be a better contrast agent in the field of magnetic resonance tumor imaging.
Topics: Animals; Contrast Media; 1-Propanol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Magnetite Nanoparticles; Neoplasms; Propanols
PubMed: 36647053
DOI: 10.1186/s12885-023-10514-0