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Hospital Medicine (London, England :... Oct 1999Prostatitis, especially chronic prostatitis, is sometimes regarded as an obscure, ill-defined condition, perhaps because the anatomical location of the gland and... (Review)
Review
Prostatitis, especially chronic prostatitis, is sometimes regarded as an obscure, ill-defined condition, perhaps because the anatomical location of the gland and ill-defined symptoms make diagnosis difficult. Treatment may appear time consuming and tiresome for doctor and patient, but by following established principles, diagnosis is often simple and management straightforward.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Humans; Male; Prostate; Prostatitis
PubMed: 10656062
DOI: 10.12968/hosp.1999.60.10.1213 -
Infection, Genetics and Evolution :... Aug 2011Several reports have shown that the incidence of prostate cancer is on the increase and that more men would be diagnosed of prostate cancer in the next decades. Many... (Review)
Review
Several reports have shown that the incidence of prostate cancer is on the increase and that more men would be diagnosed of prostate cancer in the next decades. Many approaches are being applied towards reducing the cases of prostate cancer, especially in the very rich countries. However, these have not been effective due to the poor current understanding of the pathophysiology of prostate carcinogenesis. The current work presents a review of how chronic infection and inflammation may contribute to prostate carcinogenesis.
Topics: Animals; Bacterial Infections; Humans; Male; Oxidative Stress; Prostate; Prostatic Neoplasms; Prostatitis
PubMed: 21397049
DOI: 10.1016/j.meegid.2011.03.002 -
International Braz J Urol : Official... 2008
Topics: Female; Hot Flashes; Humans; Male; Orchiectomy; Prostatic Neoplasms; Prostatism; Prostatitis; Urinary Incontinence, Stress; Urology; Vagina
PubMed: 18341714
DOI: 10.1590/s1677-55382008000100001 -
British Journal of Urology 1975A clinical diagnosis of chronic prostatitis was made on 105 adult males who were subsequently admitted and investigated by Stamey localisation techniques, psychological... (Clinical Trial)
Clinical Trial Comparative Study
A clinical diagnosis of chronic prostatitis was made on 105 adult males who were subsequently admitted and investigated by Stamey localisation techniques, psychological questionnaires, urine flow studies, cysto-urethroscopy and prostatic biopsy or transurethral prostatectomy. From the Stamey localisation studies and cultures of the tissue obtained at transurethral prostatectomy a diagnosis of bacterial prostatitis was made in 50%, of which half were Staphylococcus albus and half were well recognised urinary pathogens. Other significant pathology was found in 25% and, particularly of note, were 2 patients who presented with chronic cystitis (biopsy negative) and subsequently developed carcinoma of the bladder. Also in this group were 5 unsuspected strictures and 5 patients with poor flow rates but normal endoscopy. Investigations in the remaining 25% were all negative except for a significantly higher incidence of neuroticism when compared with the other groups and controls.
Topics: Biopsy; Chronic Disease; Clinical Trials as Topic; Endoscopy; Humans; Male; Prostate; Prostatitis; Psychology; Urine
PubMed: 769885
DOI: 10.1111/j.1464-410x.1975.tb04069.x -
BJU International Mar 2008Neurogenic inflammatory responses have recently been linked to both acute and chronic pathological conditions in the urinary tract. Neurogenic inflammation encompasses a... (Review)
Review
Neurogenic inflammatory responses have recently been linked to both acute and chronic pathological conditions in the urinary tract. Neurogenic inflammation encompasses a series of vascular and non-vascular inflammatory responses, triggered by the activation of primary sensory neurons and the subsequent release of inflammatory neuropeptides, including substance P and calcitonin gene-related peptide. The reduction of neurogenic inflammatory responses may be key in the mode of action of the adrenergic alpha(1)-adrenoceptor antagonists used to treat lower urinary tract symptoms (LUTS). Indeed, the alpha(1)-adrenoceptor antagonist alfuzosin inhibits expression of the oncogene c-fos- a marker of nociceptive pathway activation - evoked by cyclophosphamide in rats. Capsaicin ameliorates urinary bladder symptoms through its stimulatory action on the transient receptor potential vanilloid 1 (TRPV1) calcium channel, resulting in desensitization of bladder sensory nerve terminals. Involvement of the TRP cation channel, subfamily A, member 1 (TRPA1) has also been reported in models of neurogenic inflammation and nociception promoted by the cyclophosphamide metabolite, acrolein. Blockade by alfuzosin demonstrates the beneficial effects of alpha(1)-adrenoceptor antagonists on neurogenic inflammation via the transient receptor potential family of ionic channels. Consequently, these drugs may have an important role in reducing LUTS.
Topics: Adrenergic alpha-Antagonists; Animals; Calcium Channels; Humans; Male; Nerve Tissue Proteins; Neurogenic Inflammation; Prostatism; Prostatitis; Quinazolines; Rats; TRPA1 Cation Channel; TRPV Cation Channels; Transient Receptor Potential Channels; Urinary Bladder; Urinary Bladder, Overactive
PubMed: 18307678
DOI: 10.1111/j.1464-410X.2008.07493.x -
Future Oncology (London, England) May 2020
Topics: Diagnosis, Differential; Granuloma; Humans; Male; Prostate; Prostatic Neoplasms; Prostatitis
PubMed: 32180450
DOI: 10.2217/fon-2020-0185 -
The Urologic and Cutaneous Review Jan 1948
Topics: Humans; Hypertrophy; Male; Prostate; Prostatic Hyperplasia; Prostatism
PubMed: 18907533
DOI: No ID Found -
British Medical Journal Dec 1971Transrectal prostatic biopsy specimens were taken from 218 patients with prostatic symptoms-138 by the Franzen aspiration technique without anaesthesia as outpatients... (Comparative Study)
Comparative Study
Transrectal prostatic biopsy specimens were taken from 218 patients with prostatic symptoms-138 by the Franzen aspiration technique without anaesthesia as outpatients and 80 by the Silverman technique under general anaesthesia. A reliable diagnosis was obtained in 82% of the former and 95% of the latter.
Topics: Anesthesia, General; Biopsy; Humans; Male; Methods; Needles; Outpatient Clinics, Hospital; Prostate; Prostatic Neoplasms; Prostatitis; Rectum
PubMed: 5130215
DOI: 10.1136/bmj.4.5787.595 -
Drugs of Today (Barcelona, Spain : 1998) Jan 2009The present review addresses strategies to preserve prostate health, tackling the three most common prostatic problems with which men present to physicians, namely,... (Review)
Review
The present review addresses strategies to preserve prostate health, tackling the three most common prostatic problems with which men present to physicians, namely, prostate hypertrophy, prostatitis and prostate cancer. Unfortunately since a clear etiology does not exist for each of these problems, we have to rely on experimental research, epidemiologic and clinical data to design prevention strategies. A number of modifiable targets have been identified and some are cross-shared between these three very prevalent entities. However, since the pathogenesis of each condition seems multifactorial, and the interconnections between them inadequately understood, chemopreventive strategies are still in their infancy even after very large clinical trials -which produced often more questions than they delivered answers- have already been performed.
Topics: Clinical Trials as Topic; Health Promotion; Humans; Male; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Prostatitis
PubMed: 19271033
DOI: 10.1358/dot.2009.45.1.1315920 -
Urologia Internationalis 1988Twenty cases of granulomatous prostatitis are presented. They were identified, histologically or cytologically, among 1,316 patients with prostatic pathology at the...
Twenty cases of granulomatous prostatitis are presented. They were identified, histologically or cytologically, among 1,316 patients with prostatic pathology at the General Hospital of Asturias during a period of 3 years (Jan. 1984 to Dec. 1986). The etiology, histogenesis, clinical and morphological aspects, treatment and prognosis of the different types of granulomatous prostatitis, according to a classification by the authors, are discussed. The significance of the differentiation of granulomatous prostatitis from carcinoma is discussed. Fine-needle aspiration cytology (Franzen) is recommended as the diagnostic method of choice.
Topics: Biopsy, Needle; Granuloma; Humans; Male; Prostate; Prostatic Diseases; Prostatitis; Tuberculosis, Male Genital
PubMed: 3388640
DOI: 10.1159/000281313