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The Journal of Urology Mar 2015
Re: Atypical microorganisms in expressed prostatic secretion from patients with chronic prostatitis/chronic pelvic pain syndrome: microbiological results from a case-control study.
Topics: Humans; Male; Prostate; Prostatitis
PubMed: 25765391
DOI: 10.1016/j.juro.2014.12.050 -
Urology Oct 2008
Review
Topics: Chronic Disease; Humans; Male; Massage; Prostate; Prostatitis
PubMed: 18584854
DOI: 10.1016/j.urology.2008.04.030 -
World Journal of Urology Jun 2022Purpose of this study is to evaluate the diagnostic accuracy of quantitative T2/ADC values in differentiating between PCa and lesions showing non-specific inflammatory...
PURPOSE
Purpose of this study is to evaluate the diagnostic accuracy of quantitative T2/ADC values in differentiating between PCa and lesions showing non-specific inflammatory infiltrates and atrophy, features of chronic prostatitis, as the most common histologically proven differential diagnosis.
METHODS
In this retrospective, single-center cohort study, we analyzed 55 patients suspected of PCa, who underwent mpMRI (3T) including quantitative T2 maps before robot-assisted mpMRI-TRUS fusion prostate biopsy. All prostate lesions were scored according to PI-RADS v2.1. Regions of interest (ROIs) were annotated in focal lesions and normal prostate tissue. Quantitative mpMRI values from T2 mapping and ADC were compared using two-tailed t tests. Receiver operating characteristic curves (ROCs) and cutoff were calculated to differentiate between PCa and chronic prostatitis.
RESULTS
Focal lesions showed significantly lower ADC and T2 mapping values than normal prostate tissue (p < 0.001). PCa showed significantly lower ADC and T2 values than chronic prostatitis (p < 0.001). ROC analysis revealed areas under the receiver operating characteristic curves (AUCs) of 0.85 (95% CI 0.74-0.97) for quantitative ADC values and 0.84 (95% CI 0.73-0.96) for T2 mapping. A significant correlation between ADC and T2 values was observed (r = 0.70; p < 0.001).
CONCLUSION
T2 mapping showed high diagnostic accuracy for differentiating between PCa and chronic prostatitis, comparable to the performance of ADC values.
Topics: Cohort Studies; Diffusion Magnetic Resonance Imaging; Humans; Image-Guided Biopsy; Magnetic Resonance Imaging; Male; Prostate; Prostatic Neoplasms; Prostatitis; Retrospective Studies
PubMed: 35357510
DOI: 10.1007/s00345-022-03991-8 -
Postgraduate Medical Journal Jul 1956
Topics: Catheterization; Disease; Drainage; Humans; Male; Prostate; Prostatic Diseases; Prostatism; Urinary Bladder
PubMed: 13388992
DOI: 10.1136/pgmj.32.369.332 -
Journal of Gerontology Jan 1952
Topics: Aged; Disease; Disease Management; Humans; Male; Prostate; Prostatic Diseases; Prostatism
PubMed: 14898062
DOI: 10.1093/geronj/7.1.71 -
Geriatrics 1950
Topics: Humans; Male; Prostate; Prostatism
PubMed: 14802750
DOI: No ID Found -
European Urology Dec 2008
Topics: Humans; Male; Prostatism; Prostatitis; Randomized Controlled Trials as Topic
PubMed: 18036720
DOI: 10.1016/j.eururo.2007.11.027 -
Genitourinary Medicine Aug 1991
Review
Topics: Acute Disease; Humans; Male; Prostate; Prostatitis; Ultrasonography; Urinary Tract Infections
PubMed: 1916789
DOI: 10.1136/sti.67.4.279 -
Nihon Rinsho. Japanese Journal of... Dec 2002
Review
Topics: Acute Disease; Anti-Bacterial Agents; Bacterial Infections; Humans; Male; Prostate; Prostatitis
PubMed: 12599615
DOI: No ID Found -
Current Medical Research and Opinion 2015Prostatitis is a common disease in urology departments. Prostatic zinc accumulation is connected with the secretory function of the prostate, and zinc concentrations... (Meta-Analysis)
Meta-Analysis Review
BACKGROUND
Prostatitis is a common disease in urology departments. Prostatic zinc accumulation is connected with the secretory function of the prostate, and zinc concentrations present in prostatic diseases differ greatly from the normal level. Studies have investigated the effect of chronic prostatitis on zinc concentration of prostatic fluid and seminal plasma, but have shown inconsistent results. Hence, we performed a systematic literature review and meta-analysis to assess the effect of chronic prostatitis on the zinc concentration of prostatic fluid and seminal plasma.
METHODS
Systematic literature searches were conducted with PubMed, Embase, Science Direct/Elsevier, CNKI and the Cochrane Library up to March 2015 for case-control studies that involved the relationship between chronic prostatitis and zinc concentration of prostatic fluid and seminal plasma. Meta-analysis was performed with Review Manager and Stata software. Standard mean differences (SMDs) of zinc concentration were identified with 95% confidence intervals (95% CIs) in a random- or fixed-effects model.
RESULTS
Our results illustrated that the zinc concentrations in prostatic fluid and seminal plasma from chronic prostatitis patients were significantly lower than normal controls (SMD [95% CI] -246.71 [-347.97, -145.44], -20.74 [-35.11, -6.37], respectively).
LIMITATIONS
The sample size of each study was relatively small, and a total of 731 chronic prostatitis patients and 574 normal controls were investigated in all fourteen studies. Several studies related to the subject were excluded due to lack of control data or means and standard deviations.
CONCLUSIONS
The present study illustrates that there was a significant negative effect of chronic prostatitis on zinc concentrations of prostatic fluid and seminal plasma. Further studies with larger sample sizes are needed to better illuminate the negative impact of chronic prostatitis on zinc concentrations.
Topics: Chronic Disease; Humans; Male; Prostate; Prostatitis; Semen; Zinc
PubMed: 26173049
DOI: 10.1185/03007995.2015.1072707