-
American Journal of Primatology Nov 2020
Topics: Animals; Behavior, Animal; Primates
PubMed: 33089905
DOI: 10.1002/ajp.23207 -
Developmental Psychobiology Feb 2024
Topics: Recognition, Psychology; Developmental Biology
PubMed: 38388197
DOI: 10.1002/dev.22471 -
Acta Psychiatrica Scandinavica Dec 2001To review the literature on the psychobiology and pharmacotherapy of PTSD. (Review)
Review
OBJECTIVE
To review the literature on the psychobiology and pharmacotherapy of PTSD.
METHODS
Relevant studies were identified by literature searches (Pub-med, Web of Science) and through reference lists. The search was ended by May 2001.
RESULTS
There is evidence of involvement of opioid, glutamatergic, GABAergic, noradrenergic, serotonergic and neuroendocrine pathways in the pathophysiology of PTSD. Medications shown to be effective in double-blind placebo-controlled trials includes selective serotonin reuptake inhibitors, reversible and irreversible MAO-inhibitors, tricyclic antidepressants and the anticonvulsant lamotrigine. Still more agents appear promising in open-label trials.
CONCLUSION
The complexity of the psychobiology is reflected by the difficulties in treating the disorder. According to the present knowledge, suggestions for drug treatment of PTSD are made.
Topics: Glutamic Acid; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Norepinephrine; Opioid Peptides; Pituitary-Adrenal System; Serotonin; Stress Disorders, Post-Traumatic; gamma-Aminobutyric Acid
PubMed: 11782234
DOI: 10.1034/j.1600-0447.2001.00237.x -
Annals of the New York Academy of... Jun 1997
Review
Topics: Animals; Disease Models, Animal; Humans; Stress Disorders, Post-Traumatic; Stress, Psychological
PubMed: 9238216
DOI: 10.1111/j.1749-6632.1997.tb48291.x -
Revista de NeurologiaAn updated revision of the main concepts, hypothesis and clinical and experimental data about the psychobiology of consciousness. (Review)
Review
AIM
An updated revision of the main concepts, hypothesis and clinical and experimental data about the psychobiology of consciousness.
DEVELOPMENT
It describes the nature, characteristics and neural correlated of consciousness and discuss about the capacity of the human brain to understand the conscious mind.
CONCLUSIONS
Consciousness is a subjective, qualitative and unified mental state which originates behavioural flexibility. Qualia are the sensory qualities of the conscious experience. They are an executive summary of a great amount of information. Consciousness seems be mainly based on cortical mechanisms, although the thalamus and the arousal subcortical systems could have an enabling role in giving rise to it. The brain could generate consciousness by mechanisms of resonance, synchronization and/ or integration of the activity of different cortical and subcortical regions. Human brain could not have evolved enough as for understanding how objective matter becomes subjective imagination.
Topics: Brain; Consciousness; Humans; Imagination
PubMed: 19714556
DOI: No ID Found -
Scandinavian Journal of Psychology 1984
Review
Topics: Arousal; Attention; Cerebral Cortex; Conditioning, Classical; Dominance, Cerebral; Electroencephalography; Emotions; Evoked Potentials; Humans; Mental Disorders; Motivation; Orientation; Psychophysiology; Research; Scandinavian and Nordic Countries
PubMed: 6390671
DOI: 10.1111/j.1467-9450.1984.tb01013.x -
Journees Annuelles de Diabetologie de... 1992
Review
Topics: Appetite Regulation; Energy Metabolism; Feeding Behavior; Humans; Models, Biological; Nutritional Physiological Phenomena; Psychophysiology; Satiation
PubMed: 1495243
DOI: No ID Found -
Journal of Experimental Child Psychology Feb 2016
Topics: Electrophysiological Phenomena; Emotions; Human Development; Humans; Psychophysiology
PubMed: 26607502
DOI: 10.1016/j.jecp.2015.10.013 -
CNS Spectrums Jan 2008Panic disorder seems to be mediated by the neuronal circuitry and neurochemical systems that have evolved to respond to external threatening stimuli. Distant threats... (Review)
Review
Panic disorder seems to be mediated by the neuronal circuitry and neurochemical systems that have evolved to respond to external threatening stimuli. Distant threats activate prefrontal cortex (involved in complex planning of avoidance strategies), while immediate threats activate midbrain structures (involved in fast reflexive behaviors). Panic disorder may, however, also involve more specific interoceptive mechanisms. For example, the association between respiratory dysfunction and panic disorder has bolstered a false suffocation alarm hypothesis. Genetic and environmental contributors to panic disorder are beginning to be delineated. Effective pharmacotherapy and psychotherapy are able to normalize the relevant psychobiology.
Topics: Arousal; Asphyxia; Brain; Brain Mapping; Carbon Dioxide; Diagnostic and Statistical Manual of Mental Disorders; Fear; Humans; Internal-External Control; Oxygen; Panic Disorder; Positron-Emission Tomography
PubMed: 18204411
DOI: 10.1017/s1092852900016126 -
Psychoneuroendocrinology Jul 2019Using vehicles with engaged automated driving systems (ADS) ('highly automated driving', HAD) will substantially impact on future society's mobility, yet the current...
Using vehicles with engaged automated driving systems (ADS) ('highly automated driving', HAD) will substantially impact on future society's mobility, yet the current understanding of human psychobiology related to HAD is still limited. Hence, we synthesized evidence on the psychobiology of subjects using HAD, informing an integrative model of the psychobiology of HAD, and providing guidance for reporting future research on this topic. We included (non-)randomized studies assessing human peripheral biology markers of in-vehicle-users in real or simulated driving environments, using vehicles with vs. without engaged ADS, published in English until April 2018. We systematically searched Web of Science, SCOPUS, and PubMed. The search consisted of a combination of terms describing HAD and psychobiological parameters. Risk of bias was assessed regarding randomization, blinding, incomplete outcome data, selective outcome reporting, and other potential causes. We extracted data using predefined data fields. Four out of five studies included in this review (N = 194 subjects) reported associations of use of vehicles with vs. without engaged ADS with various psychobiological parameters, including heart rate, respiratory sinus arrhythmia (RSA), indicators of electrodermal activity (EDA), and masseter electromyography (EMG). Heart rate tended to be reduced during HAD along with increased EDA and EMG, with no clear indication for changes in RSA. We cannot exclude substantial risk of bias, among others because the status of engagement of ADS was mostly non-randomized. Yet, findings suggest that HAD goes along with tractable changes in peripheral biology. Informed by the conceptual endophenotype approach (Hellhammer et al., 2018, Psychoneuroendocrinology), we propose the Embodied Driving (EMBODD) model that describes how HAD reshapes vehicle use experience, and highlight how to make future ADS equipped vehicles successful regarding user's health. Based on the review, we suggest reporting guidelines for future research on the psychobiology of HAD.
Topics: Attention; Automation; Automobile Driving; Emotions; Humans; Models, Biological; Psychomotor Performance
PubMed: 30290968
DOI: 10.1016/j.psyneuen.2018.09.029