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Seminars in Ophthalmology Nov 2023To evaluate risk factors for pterygium and prevalence of periocular and systemic diseases among patients with pterygium. (Review)
Review
PURPOSE
To evaluate risk factors for pterygium and prevalence of periocular and systemic diseases among patients with pterygium.
METHODS
A retrospective case-control study was conducted among members of Clalit Health Services (CHS) in Israel, from 2001 to 2022. A total of 13,944 patients diagnosed with pterygium were included. For each case, three controls were matched among all CHS patients according to year of birth, sex, and ethnicity. Mixed models were used to assess differences in demographic characteristics, ocular and systemic diseases between the groups. Generalized estimating equation (GEE) logistic regression was used to estimate the odds ratios (OR) and adjust for confounders.
RESULTS
The average age of pterygium patients was 49 ± 17 years; 51% were male. The results showed significant associations between pterygium and risk factors of vernal kerato-conjunctivitis (OR 2.52, 95% confidence interval [CI]: [1.96-3.24]), chronic allergic conjunctivitis (OR 1.98, 95% CI: [1.65-2.39]), blepharitis (OR 1.91, 95% CI: [1.78-2.04]), chalazion (OR 1.47, 95% CI: [1.30-1.67]) and unspecified systemic allergy (OR 1.21, 95% CI [1.09-1.34]), after adjusting for rural residency status. Glaucoma (OR 0.74, 95% CI [0.64-0.85]) and smoking (OR 0.70, 95% CI [0.66-0.75]) were protective factors against pterygium.
CONCLUSION
Systemic and periocular inflammatory and allergic diseases are risk factors for pterygium.
Topics: Humans; Male; Adult; Middle Aged; Aged; Female; Pterygium; Retrospective Studies; Case-Control Studies; Risk Factors; Prevalence; Conjunctivitis, Allergic
PubMed: 37303165
DOI: 10.1080/08820538.2023.2223266 -
The British Journal of Ophthalmology Jun 2006Can we provide medical and not surgical cure?
Can we provide medical and not surgical cure?
Topics: Humans; Insulin-Like Growth Factor Binding Protein 3; Pterygium; Ultraviolet Rays
PubMed: 16714259
DOI: 10.1136/bjo.2006.091413 -
Nigerian Journal of Medicine : Journal... 2011Ptergium is a frequently encountered clinical entity in ophthalmic practice. Although commoner in the tropics compared with the temperate region, all Ophthalmologists... (Review)
Review
BACKGROUND
Ptergium is a frequently encountered clinical entity in ophthalmic practice. Although commoner in the tropics compared with the temperate region, all Ophthalmologists worldwide should be conversant with the clinical features and outcome of various approaches to surgical management. A review of the efficacy of the currently available surgical procedures for pterygium excision using postoperative recurrences as the main outcome measure is presented.
METHOD
Manual and electronic (PUBMED, MEDLINE, AJOL AND HINARI) search for medical literature relevant to clinical features and surgical treatment of pterygium was conducted. Previous reviews, large case series reports, randomized controlled trials and one meta-analysis were selected and critically reviewed.
RESULTS
Postoperative recurrence is a dominant complication of pterygium excision irrespective of the adopted surgical procedure. Pterygium excision with adjunctive therapy and ocular surface reconstruction is the current procedure of choice in view of its comparatively higher efficacy in preventing recurrence.
CONCLUSION
Recurrence is the commonest postoperative complication of pterygium excision. There is need for further research into the aetiopathogenesis and risk factors for recurrence of human pterygia.
Topics: Chemotherapy, Adjuvant; Humans; Postoperative Period; Pterygium; Recurrence
PubMed: 21970253
DOI: No ID Found -
Der Ophthalmologe : Zeitschrift Der... Jul 2021The pterygium is a frequent ultraviolet (UV) light-induced focal fibrovascular proliferation of the conjunctival tissue onto the cornea. Surgical excision should be...
The pterygium is a frequent ultraviolet (UV) light-induced focal fibrovascular proliferation of the conjunctival tissue onto the cornea. Surgical excision should be performed in the case of reduced visual acuity, progressive astigmatism, impending invasion of the optical axis and ocular surface complaints. The main factors in preventing recurrence include optimal surgical treatment by an excision combined with a free conjunctival autograft, consistent postoperative treatment with preservative-free artificial tears and topical steroids as well as long-term UV protection.
Topics: Astigmatism; Conjunctiva; Humans; Mitomycin; Pterygium; Recurrence; Transplantation, Autologous
PubMed: 33782734
DOI: 10.1007/s00347-021-01366-9 -
Der Ophthalmologe : Zeitschrift Der... Jun 2010
Comparative Study
Topics: Cross-Cultural Comparison; Cross-Sectional Studies; Cultural Diversity; Germany; Humans; Pterygium
PubMed: 20544202
DOI: 10.1007/s00347-009-2098-7 -
Journal Francais D'ophtalmologie 1990
Review
Topics: Humans; Postoperative Period; Pterygium; Recurrence; Time Factors
PubMed: 2212506
DOI: No ID Found -
Ophthalmic Epidemiology Sep 1999Pterygium is not just a degenerative disease, but may be a proliferative disorder of the ocular surface. The etiology of pterygia has intrigued researchers for... (Review)
Review
Pterygium is not just a degenerative disease, but may be a proliferative disorder of the ocular surface. The etiology of pterygia has intrigued researchers for centuries. Several surveys have consistently shown that countries nearer the equator have higher rates of pterygia. A possible reason for this geographic variation is that (ultraviolet) UV B light may be a risk factor for the development of pterygia. UV B radiation may induce cellular changes in the medial limbus of the cornea. Several case-control and cross-sectional studies have attempted to accurately quantify UV light exposure and document its relationship with pterygia. Genetic attributes and other lifestyle behaviors may also contribute to the development of pterygia. However, further research efforts are needed to enable us to better understand the relative contribution of the different risk factors and how each risk factor may be linked to pterygium formation. In addition, the underlying mechanism of the effects of UV radiation needs to be further evaluated. By readdressing these unresolved issues in a newly proposed epidemiological study, new measures might be taken to reduce incidences and improve clinical managements of diseases, in addition to preventing UV exposure by eliminating other contributory factors. Meanwhile, preventive measures such as protection of the eyes by the wearing of sunglasses with UV B protective lenses and brimmed hats outdoors are recommended.
Topics: Demography; Global Health; Humans; Prevalence; Pterygium; Risk Factors
PubMed: 10487976
DOI: 10.1076/opep.6.3.219.1504 -
The British Journal of Ophthalmology Apr 2014
Topics: Humans; Pterygium
PubMed: 24158843
DOI: 10.1136/bjophthalmol-2013-304232 -
Der Ophthalmologe : Zeitschrift Der... Jul 2021
Topics: Biomarkers; Conjunctiva; Humans; Pterygium
PubMed: 34057587
DOI: 10.1007/s00347-021-01413-5 -
BMC Ophthalmology Aug 2023Pterygium is a common ocular surface disease. Pterygium combined with corneal perforation is rare.
BACKGROUND
Pterygium is a common ocular surface disease. Pterygium combined with corneal perforation is rare.
CASE PRESENTATION
A 28-year-old female patient visited our outpatient clinic due to sudden onset of blurred vision and increased tearing in her left eye. The visual acuity was 1.0 OD and intraocular pressure (IOP) of 19.5 mmHg for the right eye with no significant abnormalities found in the anterior and posterior segments. The visual acuity of her left eye was 0.06, and IOP was 6.2 mmHg. A triangular vascular membranous tissue was seen in her left eye below the nose growing into the cornea and the pupil area was not touched. Slit-lamp examination revealed a tiny round corneal perforation in 8 o'clock position of the lesion area. Hospital diagnosis was given as pterygium combined with corneal perforation. The patient was treated with levofloxacin eye drops and autologous serum-based eye drops.
CONCLUSIONS
We report a rare case of pterygium combined with corneal perforation. Perforation is a very rare complication of pterygium. This patient received proper treatment and good result was seen. This article aimed to improve clinicians' understanding of pterygium.
Topics: Humans; Female; Adult; Pterygium; Corneal Perforation; Cornea; Ophthalmic Solutions
PubMed: 37641016
DOI: 10.1186/s12886-023-03084-z