-
Women's Health Issues : Official... 1999
Review
Topics: Adaptation, Physiological; Adolescent; Feeding and Eating Disorders; Female; Humans; Incidence; Mood Disorders; Puberty; Risk Assessment; Stress, Psychological; United States
PubMed: 10189821
DOI: 10.1016/s1049-3867(98)00052-8 -
Journal of Pediatric Endocrinology &... Jul 2001The overview in this paper focuses on ways of achieving optimal auxological results in puberty, principally in idiopathic and congenital multiple pituitary hormone... (Review)
Review
The overview in this paper focuses on ways of achieving optimal auxological results in puberty, principally in idiopathic and congenital multiple pituitary hormone deficiency (MPHD), suggested by the co-authors. We agreed that diagnosing gonadotrophin insufficiency/deficiency is difficult in young children and should be repeated in late prepuberty, but a firm diagnosis of MPHD helps avoid endocrine re-testing at the end of growth. The hypothalamic-pituitary axis must be reassessed periodically in evolving endocrinopathies, though current practice varies widely. Optimum age to induce puberty is 11-12 years in girls and 13-14 boys, and sex steroids are the preferred agents. Short-course testosterone to increase micropenis size is advantageous, but inducing early testicular maturation is not known to improve later fertility. There is also little evidence for increasing the dose of GH during puberty, though therapy should continue to final height, and possibly until peak bone mass is achieved. Delaying puberty is an option in septo-optic dysplasia, and minimising the dose of hydrocortisone is crucial in treating ACTH/cortisol insufficiency. Many unresolved questions remain in this difficult area.
Topics: Adolescent; Child; Female; Growth Disorders; Growth Hormone; Humans; Male; Pituitary Hormones; Puberty
PubMed: 11529397
DOI: 10.1515/jpem-2001-s214 -
The Journal of Clinical Endocrinology... Jun 2001Human puberty begins with the reemergence of GnRH secretion from its relative quiescence during childhood, activating a cascade of pituitary-gonadal maturation. This... (Review)
Review
Human puberty begins with the reemergence of GnRH secretion from its relative quiescence during childhood, activating a cascade of pituitary-gonadal maturation. This transition begins across a wide range of ages, and the rate of subsequent sexual maturation can be quite varied. The factors that regulate the hypothalamic-pituitary-gonadal axis and modulate the timing of puberty remain elusive, but it is clear that some regulation is under genetic control. Here, we discuss how new advances in genetic research may provide the tools to help unravel this long-standing mystery.
Topics: Genetic Variation; Gonadotropin-Releasing Hormone; Humans; Puberty; Puberty, Delayed; Puberty, Precocious; Time Factors
PubMed: 11397824
DOI: 10.1210/jcem.86.6.7603 -
Current Opinion in Endocrinology,... Feb 2009Puberty is an important developmental stage during which reproductive capacity is attained. Genetic and environmental factors both influence the timing of puberty, which... (Review)
Review
PURPOSE OF REVIEW
Puberty is an important developmental stage during which reproductive capacity is attained. Genetic and environmental factors both influence the timing of puberty, which varies greatly among individuals. However, although genetic variation is known to influence the normal spectrum of pubertal timing, the specific genes involved remain unknown.
RECENT FINDINGS
Recent genetic analyses have identified a number of genes responsible for rare disorders of pubertal timing such as hypogonadotropic hypogonadism and Kallmann syndrome. However, although the genetic basis of population variation in the timing of puberty is an active area of investigation, no genetic loci have been reproducibly associated with pubertal timing thus far.
SUMMARY
This review provides an update of the genes implicated in disorders of puberty, discusses genes and pathways that may be involved in the timing of normal puberty, and suggests additional avenues of investigation to identify genetic regulators of puberty in the general population.
Topics: Age Factors; Environment; Ethnicity; Female; Genetic Variation; Gonadal Hormones; Humans; Hypogonadism; Hypothalamo-Hypophyseal System; Kallmann Syndrome; Male; Menarche; Puberty; Puberty, Delayed; Racial Groups
PubMed: 19104234
DOI: 10.1097/MED.0b013e328320253c -
Soins. Pediatrie, Puericulture 2020What place should be given to puberty? In France, it is an intimate act that belongs only to the young girl. In Sri Lanka, it is a family and collective act that is...
What place should be given to puberty? In France, it is an intimate act that belongs only to the young girl. In Sri Lanka, it is a family and collective act that is ritualized and celebrated. Young girls born into Tamil families living in France have to make these very different logics cohabit. Analyse of a young girl's great suffering at puberty and its methods of reconstruction, which take into account the ways of doing and thinking about puberty here and there.
Topics: Adolescent; Ceremonial Behavior; Female; France; Humans; Psychopathology; Puberty; Stress, Psychological; White People
PubMed: 32951691
DOI: 10.1016/j.spp.2020.07.005 -
Schizophrenia Research Jun 1993According to the neurodevelopmental hypothesis of schizophrenia, maturational events in the brain at puberty interact with congenital defects to produce psychotic...
According to the neurodevelopmental hypothesis of schizophrenia, maturational events in the brain at puberty interact with congenital defects to produce psychotic symptoms. As girls reach puberty at a younger age than boys, we predicted that (i) females would show earlier onset of psychotic illness arising around puberty, and (ii) onset of psychosis in females would be related to menarche. Analysis of epidemiological data regarding admission to psychiatric units in (a) England over the period 1973-1986, (b) France over the period 1975-1980, as well as examination of 97 psychotic adolescents referred to an adolescent unit over a 14 year period, supported both these propositions.
Topics: Adolescent; Age Factors; Child; England; Female; France; Humans; Male; Menarche; Patient Admission; Psychiatric Status Rating Scales; Psychotic Disorders; Puberty; Schizophrenia; Schizophrenic Psychology; Sex Factors
PubMed: 8369234
DOI: 10.1016/0920-9964(93)90071-p -
Journal of Child Psychology and... Mar 1996
Review
Topics: Affect; Humans; Psychosexual Development; Puberty; Social Adjustment; Socialization
PubMed: 8707909
DOI: 10.1111/j.1469-7610.1996.tb01403.x -
The International Journal of Eating... Nov 2014Puberty is an important period of risk for the onset of eating pathology in adolescent females. This review focuses on changes in reproductive hormones during puberty as... (Review)
Review
OBJECTIVE
Puberty is an important period of risk for the onset of eating pathology in adolescent females. This review focuses on changes in reproductive hormones during puberty as one specific psychopathogenic mechanism.
METHOD
Studies of puberty and eating disorder-related phenotypes were identified using search databases and the reference sections of previous literature.
RESULTS
Correlational studies of adult women and experimental studies of animals provide evidence for the effects of reproductive hormones on eating disorder symptoms. Very few studies of puberty, however, have directly measured or tested the effects of hormonal change in samples of human adolescents. Commonly used measures of pubertal development, such as menarche or self-reported pubertal status, are relatively poor indicators of individual differences in hormones. The extent to which puberty-related hormonal change accounts for elevated risk for disordered eating remains unclear.
DISCUSSION
Future research is necessary to elucidate the specific relations between hormonal change during puberty and risk for disordered eating. In particular, there is a need for longitudinal studies with multivariate measurement of pubertal development, including direct measures of change in reproductive hormones.
Topics: Adolescent; Adult; Age Factors; Feeding and Eating Disorders; Female; Gonadal Steroid Hormones; Humans; Longitudinal Studies; Menarche; Physical Examination; Puberty; Risk Factors; Sexual Maturation
PubMed: 24919715
DOI: 10.1002/eat.22317 -
Tidsskrift For Den Norske Laegeforening... Jan 1999This paper shows how involvement in problem behaviour among 13- and 14-year-olds varies according to level of pubertal development. Furthermore, it explores whether...
This paper shows how involvement in problem behaviour among 13- and 14-year-olds varies according to level of pubertal development. Furthermore, it explores whether psychosocial factors such as characteristics of the peer network (deviance and gang membership), parental behaviour (supervision, care, and parents' frequency of alcohol intoxication) and masculine gender identity mediate this relationship. The data stem from a nation-wide representative survey of the general youth population in Norway (n = 3,139, response rate 97%). The prevalence of problem behaviour (i.e. shoplifting, truancy, vandalism etc.) increased with increasing levels of physical maturation for both sexes. The association was strongest among boys, however. Further analyses revealed that this gender difference could be attributed to the fact that early mature boys, to a greater extent than early mature girls, associate with deviant peers.
Topics: Adolescent; Adolescent Psychiatry; Family Relations; Female; Gender Identity; Humans; Interpersonal Relations; Male; Psychology, Adolescent; Puberty; Sex Characteristics; Social Adjustment; Social Behavior Disorders; Surveys and Questionnaires
PubMed: 10081353
DOI: No ID Found -
Journal of Pediatric Nursing Feb 2001
Topics: Adaptation, Psychological; Adolescent; Age Factors; Child; Female; Humans; Puberty; Sexuality
PubMed: 11247527
DOI: 10.1053/jpdn.2001.22361