-
La Tunisie Medicale Jun 2009
Topics: Female; Humans; Lung Neoplasms; Middle Aged; Pulmonary Blastoma
PubMed: 19927791
DOI: No ID Found -
The British Journal of Radiology May 2005Pulmonary blastoma is a relatively rare aggressive adult malignancy. The clinical and radiographic features of two cases are described and the literature reviewed.... (Review)
Review
Pulmonary blastoma is a relatively rare aggressive adult malignancy. The clinical and radiographic features of two cases are described and the literature reviewed. Pulmonary blastoma usually presents radiologically as a well-defined mass lesion on chest radiography, which may be large enough to completely opacify the hemithorax and cause mediastinal shift. On CT, pulmonary blastoma is seen as a mixed solid and cystic lesion with variable contrast enhancement and a necrotic centre. Pleural effusion may be present but is not the predominant abnormality. Our cases are unusual as recurrent pleural effusions in the absence of a significant lung mass were the presenting findings.
Topics: Adult; Female; Humans; Lung Neoplasms; Pleural Effusion; Pulmonary Blastoma; Recurrence; Tomography, X-Ray Computed
PubMed: 15845939
DOI: 10.1259/bjr/45172814 -
Journal of the Indian Medical... Feb 2013Pleuropulmonary blastoma is a rare and aggressive malignant tumour that affects young children. A case of pleuropulmonary blastoma has been presented in a 9-year-old...
Pleuropulmonary blastoma is a rare and aggressive malignant tumour that affects young children. A case of pleuropulmonary blastoma has been presented in a 9-year-old male child who was initially diagnosed and treated as pulmonary tuberculosis. Computed tomography of chest revealed a large heterogeneously enhancing mass with calcification in left hemithorax and left pleural effusion. The mass was seen to invade mediastinum and left hemidiaphragm. Thoracotomy revealed unresectable tumour involving both lobes of left lung with invasion of mediastinum and left hemidiaphragm. Biopsy confirmed type II pleuropulmonary blastoma and the child was treated with chemotherapy and radiotherapy.
Topics: Child; Combined Modality Therapy; Diagnosis, Differential; Humans; Lung Neoplasms; Male; Neoplasm Invasiveness; Pulmonary Blastoma; Thoracotomy; Tomography, X-Ray Computed
PubMed: 24003574
DOI: No ID Found -
Lung Cancer (Amsterdam, Netherlands) May 2002Pulmonary blastoma (PB) is a rare malignant tumor of the lung. Treatment is primarily surgical, although, combination chemotherapy has been reported to result in... (Review)
Review
Pulmonary blastoma (PB) is a rare malignant tumor of the lung. Treatment is primarily surgical, although, combination chemotherapy has been reported to result in objective responses in inoperable tumors or after incomplete resections. To our knowledge, this is the first report of a very radiosensitive PB, which showed major tumor reduction after several fractions of radiotherapy without further tumor regression after additional chemotherapy with cisplatin and etoposide. The literature on the treatment of PB is reviewed.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Epithelial Cells; Etoposide; Humans; Lung Neoplasms; Male; Middle Aged; Pulmonary Blastoma; Radiotherapy Dosage; Stromal Cells; Tomography, X-Ray Computed
PubMed: 11955657
DOI: 10.1016/s0169-5002(01)00465-2 -
Respiratory Medicine Jul 2006Pulmonary blastoma is a rare malignant lung tumor with a poor prognosis. It is composed of immature mesenchymal and epithelial components that resemble fetal lung...
Pulmonary blastoma is a rare malignant lung tumor with a poor prognosis. It is composed of immature mesenchymal and epithelial components that resemble fetal lung tissue. We aimed to share our treatment results in biphasic pulmonary blastoma. In Ataturk Chest Disease and Thoracic Surgery Center, five patients with biphasic pulmonary blastoma (four men, one woman, aged between 27 and 61-mean 39.4) were treated between 1987 and 2000 (0.3% of operated NSCC). Hemoptysis, cough, chest pain and dyspnea were the symptoms. Anemia and high erythrocyte sedimentation rate were determined in two patients. Radiological examinations revealed a mass in four patients and massive pleural effusion in one. None of the patients were diagnosed preoperatively and hence all patients underwent exploratory thoracotomy. Three lobectomy, one pneumonectomy and one wedge resection were performed. Histopathological examinations revealed biphasic pulmonary blastoma in all the patients. Pathological stagings were as follows: 1 patient in T1N0M0 and 1 patient in T2N0M0 (198 and 112 months survival, respectively), three patients in T2N1M0 (9,10,17 months survival). In follow up period, prostate carcinoma and rectum carcinoma were detected as second primary tumors in the patient in stage T2N0M0. In patients who have small size tumors without nodal involvement, long-term survival can be obtained with radical surgery; even in biphasic pulmonary blastomas. According to our limited experiences, N1 nodal involvement shows very poor prognosis.
Topics: Adult; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Prognosis; Pulmonary Blastoma; Tomography, X-Ray Computed; Treatment Outcome
PubMed: 16332433
DOI: 10.1016/j.rmed.2005.10.026 -
Virchows Archiv : An International... Sep 2020
Topics: Cystic Adenomatoid Malformation of Lung, Congenital; Humans; Pulmonary Blastoma
PubMed: 32300881
DOI: 10.1007/s00428-020-02811-x -
Respirology (Carlton, Vic.) May 2006Pulmonary blastoma is a rare tumour of the lung composed of epithelial and mesenchymal elements that morphologically resemble the embryonal structure of the lung. The...
Pulmonary blastoma is a rare tumour of the lung composed of epithelial and mesenchymal elements that morphologically resemble the embryonal structure of the lung. The authors report a 79-year-old man who was diagnosed with a pulmonary blastoma within bronchioloalveolar cell carcinoma. Macroscopic, histopathological and immunohistochemical findings suggested that the pulmonary blastoma was closely associated with the bronchioloalveolar cell carcinoma.
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Aged; Biopsy; Diagnosis, Differential; Humans; Lung Neoplasms; Male; Neoplasms, Multiple Primary; Pneumonectomy; Pulmonary Blastoma; Tomography, X-Ray Computed
PubMed: 16635096
DOI: 10.1111/j.1440-1843.2006.00854.x -
International Journal of Gynecological... Jan 2009Pulmonary blastoma (PB) is a rare and aggressive pulmonary malignancy. A 38-year-old woman was diagnosed as biphasic PB (1 subgroup of sarcomatoid carcinoma) and treated...
Pulmonary blastoma (PB) is a rare and aggressive pulmonary malignancy. A 38-year-old woman was diagnosed as biphasic PB (1 subgroup of sarcomatoid carcinoma) and treated by surgery, radiotherapy, and chemotherapy. Six months later, the patient presented with menstrual disorder and a mass in the abdominal-pelvic cavity. Abdominal hysterectomy and bilateral salpingo-oophorectomy showed the morphology of metastatic PB in both ovaries. The metastatic tumor was composed exclusively of epithelial components resembling well-differentiated fetal adenocarcinoma. To our knowledge, this is the first reported case of bilateral ovarian metastasis from biphasic PB.
Topics: Adult; Female; Humans; Lung Neoplasms; Ovarian Neoplasms; Pulmonary Blastoma
PubMed: 19047906
DOI: 10.1097/PGP.0b013e31817f8d00 -
Indian Journal of Pathology &... 2010
Topics: Adult; Histocytochemistry; Humans; Lung Neoplasms; Male; Microscopy; Pulmonary Blastoma; Radiography, Thoracic; Tomography, X-Ray Computed; Yolk Sac
PubMed: 21045461
DOI: 10.4103/0377-4929.72027 -
Journal of Pediatric Surgery Dec 1994Pulmonary blastoma is a rare primary neoplasm of the lung. Approximately 25% of the reported cases have occurred in pediatric patients. The authors found 45 cases of... (Review)
Review
Pulmonary blastoma is a rare primary neoplasm of the lung. Approximately 25% of the reported cases have occurred in pediatric patients. The authors found 45 cases of these tumors in children aged < or = 16 years, and report two more cases of pulmonary blastoma--in a 3 1/2-year-old boy and a 22-month-old girl. Because these tumors are considered malignant, surgical excision is recommended.
Topics: Child, Preschool; Female; Humans; Infant; Lung Neoplasms; Male; Pulmonary Blastoma
PubMed: 7877026
DOI: 10.1016/0022-3468(94)90214-3