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Kyobu Geka. the Japanese Journal of... Jun 2022A 23-year-old man was referred to our department for chest abnormal shadow. Computed tomography (CT) of the chest revealed a well-defined 1.2 cm nodule in the S4 segment...
A 23-year-old man was referred to our department for chest abnormal shadow. Computed tomography (CT) of the chest revealed a well-defined 1.2 cm nodule in the S4 segment of the right middle lobe and a well-defined 1.8 cm nodule in the S10 segment of the right lower lobe. The patient was found to have a fracture in the left fifth rib due to the falling accident at playing snowboard, two months before. He was diagnosed with a benign tumor in the right middle lobe and the right lower lobe and was performed surgery. Thoracoscopy revealed a yellowish-brown tumor in the right middle lobe( S4) and a yellow-brown tumor in the right lower lobe( S10). Both lesions were diagnosed as clots by rapid intraoperative pathologic diagnosis. Histopathological diagnosis was an intrapulmonary hematoma.
Topics: Adult; Hematoma; Humans; Lung; Lung Diseases; Lung Neoplasms; Male; Thoracic Injuries; Young Adult
PubMed: 35618696
DOI: No ID Found -
British Medical Journal Feb 1968
Topics: Brain Edema; Hematoma, Subdural; Hemorrhage; Humans; Hyaline Membrane Disease; Hypoxia; Infant, Newborn; Infant, Newborn, Diseases; Kernicterus; Lung; Lung Diseases; Oxygen Inhalation Therapy
PubMed: 5635931
DOI: No ID Found -
The American Review of Respiratory... Dec 1990A 67-yr-old man, known to have chronic obstructive lung disease, developed bilateral localized pulmonary densities on chest radiographs after cardiopulmonary...
A 67-yr-old man, known to have chronic obstructive lung disease, developed bilateral localized pulmonary densities on chest radiographs after cardiopulmonary resuscitation. An autopsy disclosed bilateral intrapulmonary hematomas without communication with bronchi, pulmonary arteries, or pleural cavities. We suggest blunt pulmonary injury is the most probable cause of the hematomas and discuss its pathogenic mechanism. Intrapulmonary hematomas should be considered in the differential diagnosis of pulmonary densities developing after a vigorous resuscitation.
Topics: Aged; Hematoma; Humans; Lung Diseases; Lung Injury; Male; Resuscitation; Wounds, Nonpenetrating
PubMed: 2252266
DOI: 10.1164/ajrccm/142.6_Pt_1.1449 -
The American Journal of Gastroenterology May 1972
Topics: Abdominal Muscles; Adult; Aged; Asthma; Dyspnea; Female; Hematoma; Humans; Male; Pulmonary Emphysema; Radiography; Respiratory Tract Infections; Tetracycline; Thrombophlebitis
PubMed: 4260551
DOI: No ID Found -
The British Journal of Radiology Sep 1961
Topics: Hematoma; Humans; Lung Injury; Radiography
PubMed: 13770960
DOI: 10.1259/0007-1285-34-405-587 -
The American Journal of Roentgenology,... Dec 1974
Topics: Hematoma; Humans; Lung; Lung Diseases; Lung Neoplasms; Neck Injuries; Radiography; Subclavian Artery; Tuberculosis, Pulmonary
PubMed: 4458463
DOI: 10.2214/ajr.122.4.837 -
Internal Medicine (Tokyo, Japan) Jun 2023A chronic expanding haematoma (CEH) is an encapsulated mass that gradually increases in size from repeated internal bleeding and neovascularization. We herein report a...
A chronic expanding haematoma (CEH) is an encapsulated mass that gradually increases in size from repeated internal bleeding and neovascularization. We herein report a 69-year-old man who was admitted with dyspnoea on exertion after undergoing thymic carcinoma resection 17 years ago. Chest computed tomography showed a heterogeneous mass in the anterior mediastinum and compression of the right ventricle, and pulmonary artery. Right cardiac catheterisation revealed pulmonary hypertension that was relieved after resection of the diagnosed CEH mass. This report highlights the mechanism underlying anterior mediastinal CEH-induced stenotic compression of the right ventricle-pulmonary artery outflow and subsequent pulmonary hypertension.
Topics: Male; Humans; Aged; Heart Ventricles; Constriction, Pathologic; Hypertension, Pulmonary; Pulmonary Artery; Hematoma
PubMed: 36261375
DOI: 10.2169/internalmedicine.0433-22 -
Polski Merkuriusz Lekarski : Organ... Apr 2022COVID-19 patients, particularly those with severe pulmonary involvement, are at an increased thromboembolic risk related, among various causes, to the cytokine storm and...
UNLABELLED
COVID-19 patients, particularly those with severe pulmonary involvement, are at an increased thromboembolic risk related, among various causes, to the cytokine storm and excessive activation of the coagulation cascade and platelets. Different intensity of anticoagulation for them is proposed, mainly with low molecular weight heparins (LMWHs); in a confirmed pulmonary embolism (PE) the therapeutic dose of LMWH is routinely used. Some authors suggest that hemorrhagic complications in COVID-19 patients are rare. At the same time, one can find reports on internal bleeding, including retroperitoneal hematoma (RPH) and other abdominal hematomas.
CASE REPORTS
The authors describe 5 cases (3 of those aged more than 80 years) with giant RPHs and with moderate/severe COVID-19 pneumonia, treated before RPH diagnosis with different enoxaparin doses. The therapeutic dose was given to the male with verified PE limited to the segmental/subsegmental pulmonary arteries and initially to the female in whom echocardiography was strongly suggestive of PE, yet this diagnosis was excluded on CT angiography. In one patient, the enoxaparin dose was escalated from 40 mg bd to 60 mg bd after the D-dimer increase. Two patients had bleeding complications despite the enoxaparin dose restricted to 40 mg/daily or bd. Two males had a coexistent psoas hematoma while in only one female there was a coexistent femoral hematoma. RPHs occurred between day 4 and 14 of hospitalization and all were treated conservatively. Three patients who died were particularly charged, so their deaths were not merely directly associated with RPH, which was closely analyzed in one autopsy performed. The authors underline that the choice of anticoagulation intensity in patients with COVID-19 pneumonia without venous thromboembolism seems sometimes difficult but recent publications indicate the low prophylactic enoxaparin dose as an optimal option. Anticoagulation dose escalation based only on the D-dimer level may not be appropriate for certain patients; moreover, the D-dimer increase is commonly observed during internal bleeding.
Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; COVID-19; Enoxaparin; Female; Hematoma; Heparin, Low-Molecular-Weight; Humans; Male; Middle Aged; Pulmonary Embolism
PubMed: 35436275
DOI: No ID Found -
BMJ Case Reports Oct 2019Apixaban (Eliquis) is a direct acting oral anticoagulant (DOAC) indicated for treatment of deep vein thrombosis, non-valvular atrial fibrillation, pulmonary embolism and...
Apixaban (Eliquis) is a direct acting oral anticoagulant (DOAC) indicated for treatment of deep vein thrombosis, non-valvular atrial fibrillation, pulmonary embolism and postoperative venous thromboprophylaxis following hip or knee replacement. Complications are minimal and include, but are not limited to, bleeding and intracranial haemorrhage, and haematoma formation. Our patient is a 73-year-old woman who presented with clinical and radiographic findings of small bowel obstruction. She was found to be taking apixaban for atrial fibrillation. CT scan showed small bowel intussusception. She underwent an exploratory laparotomy and resection of the small bowel intussusception with primary side-to-side anastomosis. Histopathological examination showed that the intussusception was caused by an intramural haematoma. This case presents a rare instance of adult intussusception caused by a DOAC. To our knowledge, no case of intussusception caused by apixaban has yet been found in literature.
Topics: Aged; Atrial Fibrillation; Diagnosis, Differential; Female; Hematoma; Humans; Ileal Diseases; Intestine, Small; Intussusception; Pyrazoles; Pyridones
PubMed: 31653627
DOI: 10.1136/bcr-2019-230952 -
Equine Veterinary Journal Jul 2007Exercise-induced pulmonary haemorrhage (EIPH) occurs in the majority of horses performing strenuous exercise. Associated pulmonary lesions include alveolar and airway...
REASONS FOR PERFORMING STUDY
Exercise-induced pulmonary haemorrhage (EIPH) occurs in the majority of horses performing strenuous exercise. Associated pulmonary lesions include alveolar and airway wall fibrosis, which may enhance the severity of EIPH. Further work is required to understand the pulmonary response to blood in the equine airways.
OBJECTIVES
To confirm that a single instillation of autologous blood into horse airways is associated with alveolar wall fibrosis, and to determine if blood in the airways is also associated with peribronchiolar fibrosis.
METHODS
Paired regions of each lung were inoculated with blood or saline at 14 and 7 days, and 48, 24 and 6 h before euthanasia. Resulting lesions were described histologically and alveolar and airway wall collagen was quantified.
RESULTS
The main lesion observed on histology was hypertrophy and hyperplasia of type II pneumocytes at 7 days after blood instillation. This lesion was no longer present at 14 days. There were no significant effects of lung region, treatment (saline or autologous blood instillation), nor significant treatment-time interactions in the amount of collagen in the interstitium or in the peribronchial regions.
CONCLUSION
A single instillation of autologous blood in lung regions is not associated with pulmonary fibrosis.
POTENTIAL RELEVANCE
Pulmonary fibrosis and lung remodelling, characteristic of EIPH, are important because these lesions may enhance the severity of bleeding during exercise. A single instillation of autologous blood in the airspaces of the lung is not associated with pulmonary fibrosis. Therefore the pulmonary fibrosis described in EIPH must have other causes, such as repetitive bleeds, or the presence of blood in the pulmonary interstitium in addition to the airspaces. Prevention of pulmonary fibrosis through therapeutic intervention requires a better understanding of these mechanisms.
Topics: Animals; Female; Hemorrhage; Horse Diseases; Horses; Lung; Lung Diseases; Male; Physical Exertion; Pulmonary Alveoli; Pulmonary Fibrosis; Severity of Illness Index
PubMed: 17722725
DOI: 10.2746/042516407x174513