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Chest Oct 2022
Topics: Humans; Pressure Ulcer; Suppuration
PubMed: 36210115
DOI: 10.1016/j.chest.2022.06.041 -
Respirology (Carlton, Vic.) Jul 2022
Topics: Empyema, Pleural; Fibrinolytic Agents; Humans; Pleural Effusion; Suppuration; Thrombolytic Therapy
PubMed: 35560748
DOI: 10.1111/resp.14293 -
The Israel Medical Association Journal... Feb 2023
Topics: Humans; Abscess; Suppuration
PubMed: 36841991
DOI: No ID Found -
Ophthalmology. Glaucoma 2023
Topics: Humans; Suppuration
PubMed: 37318423
DOI: 10.1016/j.ogla.2023.05.007 -
Nature Chemical Biology Feb 2020
Topics: Gene Expression; Humans; Hydro-Lyases; MicroRNAs; RNA, Transfer; Suppuration
PubMed: 31974524
DOI: 10.1038/s41589-019-0450-z -
JAMA Dermatology Mar 2016
Topics: Autoexperimentation; Dermatology; Gonorrhea; History, 18th Century; History, 19th Century; History, 20th Century; Humans; Male; Suppuration; Syphilis
PubMed: 26964053
DOI: 10.1001/jamadermatol.2015.1883 -
CMAJ : Canadian Medical Association... Mar 2017
Topics: Suppuration
PubMed: 28385823
DOI: 10.1503/cmaj.732795 -
Arthritis Research & Therapy 2011
Topics: Body Fluids; Extracellular Space; Humans; Intracellular Space; Neutrophils; Suppuration
PubMed: 22029909
DOI: 10.1186/ar3477 -
Scandinavian Journal of Surgery : SJS :... Mar 2019Appendicitis is a common presentation to hospital with appendectomy being the treatment of choice. Pre-operative administration of broad-spectrum antibiotics is common,...
BACKGROUND AND AIMS:
Appendicitis is a common presentation to hospital with appendectomy being the treatment of choice. Pre-operative administration of broad-spectrum antibiotics is common, but obtaining intra-abdominal pus samples is not. After an initial 6-month retrospective audit and departmental teaching on the importance of intra-peritoneal pus sampling, we aimed to determine whether intra-operative pus samples changed antibiotic management.
MATERIALS AND METHODS:
Following the initial audit cycle, a 6-month prospective cohort study was conducted. Clinical data were collected on a predetermined proforma to assess the effectiveness of the intervention and antibiotic prescribing practice. The data collected during the whole 1-year period was analyzed.
RESULTS:
During the 1-year period, 440 patients were identified as undergoing a laparoscopic procedure. After exclusion, 261 patients were identified as undergoing laparoscopic appendectomies, of which 141 (54%) were classified as complicated laparoscopic appendectomies. A total of 35 out of 141 (25%) pus samples were sent of which 24 (17%) resulted in positive cultures, with only nine of these positive cultures reported prior to the patient being discharged. No patient had their antibiotic regimen changed as a result of the culture results. There were three cases of cultures resistant to local antibiotics, but without significant clinical outcome. One of these patients developed a post-operative complication, but the antibiotic regimen was changed to broad spectrum rather than a specific antibiotic based on culture sensitivity. Of the 141 patients with complicated laparoscopic appendectomies, five (3.5%) developed post-operative complications: one readmission requiring a laparoscopic washout for pelvic collection, three (2%) cases of pelvic collections managed conservatively, and one case of prolonged paralytic ileus managed non-operatively.
CONCLUSION:
Overall, none of the patients with positive cultures had a change in prescribed antibiotics based on culture results. Hence, the routine practice of intra-peritoneal pus sampling following complicated appendicitis remains of little clinical value.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Appendectomy; Appendicitis; Child; Child, Preschool; Diagnostic Tests, Routine; Female; Humans; Laparoscopy; Male; Medical Audit; Middle Aged; Prospective Studies; Suppuration; Young Adult
PubMed: 29973114
DOI: 10.1177/1457496918783721 -
British Journal of Hospital Medicine Sep 1983
Comparative Study Review
Topics: Abdomen; Abscess; Gallium Radioisotopes; Humans; Indium; Leukocytes; Radioisotopes; Suppuration; Technetium; Tomography, X-Ray Computed; Ultrasonography
PubMed: 6354331
DOI: No ID Found