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European Surgical Research. Europaische... 1991Jejunal or colonic segments are currently used as esophageal substitutes after resection of intractable peptic stenoses. The present study was carried out in order to...
Jejunal or colonic segments are currently used as esophageal substitutes after resection of intractable peptic stenoses. The present study was carried out in order to investigate the effects of the jejunal or colonic mucosa on antral gastrin (G) cells. Colonic or jejunal patches with intact vascular supply were sutured to the pyloric antrum or the higher portion of the gastric body in 40 rats. Ten further animals were used as controls. Three to 4 months after surgery, the serum gastrin levels were weekly determined in fasted (24 h) and freely fed rats using radioimmunoassay. The pyloric antrum was then removed, and the G cell density was assessed with an immunoperoxidase method. Transposal of the colonic mucosa to the antrum increased G cell density and basal serum gastrin levels, while grafting of the jejunal mucosa did not. G cell proliferation proved to be dependent on the topographic location of the colonic patch with respect to the pyloric antrum. Serum gastrin values in freely fed rats tended to be greater in the colon-to-antrum transposition group than in the other experimental groups, but the difference was not significant. In conclusion, variations between the properties of the jejunal and colonic mucosa would include their uneven effects on antral G cells.
Topics: Animals; Cell Division; Colon; Gastrins; Hyperplasia; Intestinal Mucosa; Jejunum; Pyloric Antrum; Rats; Rats, Inbred Strains
PubMed: 1802736
DOI: 10.1159/000129172 -
Indian Journal of Gastroenterology :... Jul 2014
Topics: Gastrectomy; Gastric Mucosa; Gastroscopy; Humans; Hyperplasia; Male; Middle Aged; Pyloric Antrum
PubMed: 23982703
DOI: 10.1007/s12664-013-0361-y -
Journal of Korean Medical Science Jan 2010Primary or idiopathic hypertrophy of the pyloric muscle in adult, so called torus hyperplasia, is an infrequent but an established entity. It is caused by a circular...
Primary or idiopathic hypertrophy of the pyloric muscle in adult, so called torus hyperplasia, is an infrequent but an established entity. It is caused by a circular muscle hypertrophy affecting the lesser curvature near the pylorus. Since most of the lesions are difficult to differentiate from tumor, distal gastrectomy is usually preformed to rule out most causes of pyloric lesions including neoplastic ones through a pathological study. A 56-yr-old man with a family history of gastric cancer presented with abdominal discomfort of 1 month duration. Upper gastrointestinal endoscopy showed a 1.0 cm sized irregular submucosal lesion proximal to the pylorus to the distal antrum on the lesser curvature. On colonoscopy examination, a 1.5 cm sized protruding mass was noticed on the appendiceal orifice. Gastrectomy and cecectomy were done, and histological section revealed marked hypertrophy of the distal circular pyloric musculature and an appendiceal mucocele. To the best of our knowledge, this is the first case of torus hyperplasia with appendiceal mucocele which is found incidentally.
Topics: Cystadenoma, Mucinous; Endoscopy, Gastrointestinal; Gastrectomy; Humans; Hyperplasia; Male; Middle Aged; Pyloric Antrum; Tomography, X-Ray Computed
PubMed: 20054408
DOI: 10.3346/jkms.2010.25.1.152 -
The New England Journal of Medicine Jun 1979
Topics: Anemia, Pernicious; Animals; Autoantibodies; Autoimmune Diseases; Gastritis; Humans; Immunoglobulin G; Pyloric Antrum; Rats
PubMed: 440393
DOI: 10.1056/NEJM197906213002511 -
Radical resection of the pyloric antrum and its effect on gastric emptying after sleeve gastrectomy.Obesity Surgery Apr 2013The surgical technique of laparoscopic sleeve gastrectomy (LSG) has not been fully standardized yet and there is the unresolved question of what is the optimum size of... (Randomized Controlled Trial)
Randomized Controlled Trial
BACKGROUND
The surgical technique of laparoscopic sleeve gastrectomy (LSG) has not been fully standardized yet and there is the unresolved question of what is the optimum size of retained pyloric antrum. The aim of our research was to prove that even after a radical resection of the pyloric antrum the physiological stomach evacuation function can still be preserved.
METHODS
Our study was based on 12 patients, who were randomly divided into two groups. Patients undergoing radical antrum resection (RA group) underwent gastric emptying scintigraphy to determine the evacuation half-time (T1/2) and food retention in the 90th minute of the test (%GE) both before the operation and 3 months afterward. Patients in whom the antrum was preserved (PA group) served as a control group for comparison of postoperative weight loss (in kilogram), decrease in body mass index (BMI), and decline in excess weight (%EWL). The resulting changes were statistically processed.
RESULTS
In the RA group, the average time T1/2 declined from 57.5 to 32.25 min (p = 0.016) and average retention %GE dropped from 20.5 to 9.5% (p = 0.073). Differences in the average values of weight, BMI, or %EWL between both groups were of no statistical significance (p > 0.8).
CONCLUSIONS
In the RA group, an increase in gastric emptying postoperatively was noted. Complications such as failure of stomach evacuation were not observed in the RA group. Our results suggest that even more radical resection of the pyloric antrum performed by LSG is possible without concerns of postoperative disorder of the stomach evacuation function.
Topics: Adult; Analysis of Variance; Body Mass Index; Body Weight; Female; Follow-Up Studies; Gastric Emptying; Gastroplasty; Humans; Laparoscopy; Male; Middle Aged; Obesity, Morbid; Pilot Projects; Pyloric Antrum; Radionuclide Imaging; Treatment Outcome; Weight Loss
PubMed: 23306796
DOI: 10.1007/s11695-012-0850-6 -
The American Journal of Gastroenterology Apr 2017
Topics: Aged, 80 and over; Endoscopy, Digestive System; Female; Humans; Melanosis; Pyloric Antrum
PubMed: 28381850
DOI: 10.1038/ajg.2016.576 -
Surgical and Radiologic Anatomy : SRA Nov 2019Stomach is the most dilated part of the digestive tube. The shape of the stomach could vary frequently without any clinical symptoms. Abnormality of pylorus including...
Stomach is the most dilated part of the digestive tube. The shape of the stomach could vary frequently without any clinical symptoms. Abnormality of pylorus including double pylorus and congenital pyloric stenosis has been reported but pyloric ectopic opening has not been reported before. We found a rare case of pyloric ectopic opening in the stomach body with a "hammer" shape stomach in a 72-year-old man. The patient complained of upper left abdominal with no past medical history or surgery history. The double-contrast examination showed a "hammer" shape stomach, with the pylorus opening high at the lesser curvature and enlarged distal end of the stomach. The gastrointestinal endoscopy showed that the pyloric antrum was approximately 3 cm below the cardia with a round and poor functioning opening. No obvious abnormalities in the bulb and descending part of the duodenum were observed. A large ulcer with whitish exudate covering the base was found on the posterior wall. Histological examination of the ulcer showed broken mucosal glands with atypical hyperplasia and focal carcinogenesis. This case shows a probably congenital pyloric ectopic opening in the gastric body with a "hammer"-shaped stomach, adding a new gastric morphological variation.
Topics: Aged; Anatomic Variation; Barium; Contrast Media; Endoscopy, Gastrointestinal; Humans; Male; Pyloric Antrum; Radiography
PubMed: 31264000
DOI: 10.1007/s00276-019-02276-x -
Journal of Medical Imaging and... Oct 2018
Review
Topics: Barium; Crohn Disease; Diagnostic Imaging; Humans; Pyloric Antrum
PubMed: 30309108
DOI: 10.1111/1754-9485.45_12784 -
Digestive Diseases and Sciences Jun 1982
Topics: Cholestasis; Female; Gastrostomy; Hepatic Duct, Common; Humans; Methods; Pregnancy; Pyloric Antrum; Radiography
PubMed: 7083992
DOI: 10.1007/BF01296739 -
AJR. American Journal of Roentgenology Sep 1985In 3.25% of 400 consecutive double-contrast upper gastrointestinal examinations, a prominent fold in the prepyloric gastric antrum that extends through the pylorus into...
In 3.25% of 400 consecutive double-contrast upper gastrointestinal examinations, a prominent fold in the prepyloric gastric antrum that extends through the pylorus into the base of the duodenal bulb has been identified. Although the clinical significance of this fold is undetermined, endoscopic evaluation suggests it is a manifestation of chronic gastritis. This fold may simulate other entities, but can be distinguished by its characteristic features. Proper recognition may prevent unnecessary procedures such as endoscopy and biopsy.
Topics: Gastritis; Humans; Hypertrophy; Pyloric Antrum; Radiography
PubMed: 3875259
DOI: 10.2214/ajr.145.3.547