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Journal of Oral Science Dec 2006Pyogenic granuloma is one of the inflammatory hyperplasias seen in the oral cavity. This term is a misnomer because the lesion is unrelated to infection and in reality... (Review)
Review
Pyogenic granuloma is one of the inflammatory hyperplasias seen in the oral cavity. This term is a misnomer because the lesion is unrelated to infection and in reality arises in response to various stimuli such as low-grade local irritation, traumatic injury or hormonal factors. It predominantly occurs in the second decade of life in young females, possibly because of the vascular effects of female hormones. Clinically, oral pyogenic granuloma is a smooth or lobulated exophytic lesion manifesting as small, red erythematous papules on a pedunculated or sometimes sessile base, which is usually hemorrhagic. The surface ranges from pink to red to purple, depending on the age of the lesion. Although excisional surgery is the treatment of choice for it, some other treatment protocols such as the use of Nd:YAG laser, flash lamp pulsed dye laser, cryosurgery, intralesional injection of ethanol or corticosteroid and sodium tetradecyl sulfate sclerotherapy have been proposed. Because of the high frequency of pyogenic granuloma in the oral cavity, especially during pregnancy, and necessity for proper diagnosis and treatment, a complete review of published information and investigations about this lesion, in addition to knowledge about new approaches for its treatment is presented.
Topics: Contraceptives, Oral; Diagnosis, Differential; Facial Injuries; Female; Gingival Diseases; Gingival Neoplasms; Gonadal Steroid Hormones; Granuloma, Pyogenic; Humans; Pregnancy; Pregnancy Complications
PubMed: 17220613
DOI: 10.2334/josnusd.48.167 -
The New England Journal of Medicine Nov 2022
Topics: Humans; Granuloma, Pyogenic
PubMed: 36416770
DOI: 10.1056/NEJMicm2204602 -
International Journal of Molecular... Nov 2023Pyogenic granuloma (PG) is a benign vascular lesion found predominantly in the oral cavity. Characterized by rapid growth and propensity to bleed, PG presents diagnostic... (Review)
Review
Pyogenic granuloma (PG) is a benign vascular lesion found predominantly in the oral cavity. Characterized by rapid growth and propensity to bleed, PG presents diagnostic challenges due to its similarity and alarming proliferation. This narrative review synthesizes current knowledge on the epidemiology, etiopathogenesis, clinical manifestations, and management of oral PG, with emphasis on recent advances in diagnostic and therapeutic approaches. The epidemiology of the injury is meticulously analyzed, revealing a higher incidence in women and a wide range of ages of onset. It delves into the etiopathogenesis, highlighting the uncertainty surrounding the exact causal factors, although historical attributions suggest an infectious origin. It exhaustively analyzes the clinical and histopathological aspects of oral PG, offering information on its various presentations and the importance of an accurate diagnosis to guide effective treatment. It details treatment strategies, emphasizing the personalized approach based on individual patient characteristics. This comprehensive review consolidates current knowledge on oral PG, highlighting the need for further research to clarify its pathogenesis and optimize treatment protocols.
Topics: Humans; Female; Granuloma, Pyogenic; Mouth Mucosa; Mouth
PubMed: 38069207
DOI: 10.3390/ijms242316885 -
Cutis Oct 2004Pyogenic granuloma (PG) is an acquired vascular lesion of the skin and mucous membranes common to the pediatric age group. PG appears as a solitary red nodule on the... (Review)
Review
Pyogenic granuloma (PG) is an acquired vascular lesion of the skin and mucous membranes common to the pediatric age group. PG appears as a solitary red nodule on the head or neck. The nodule is prone to hemorrhage, and bleeding is often refractory to pressure. The etiology of PG is unknown, but proposed agents include trauma, infection, and preceding dermatoses. Several surgical treatments are available with variable cosmetic results and recurrence rates.
Topics: Child; Diagnosis, Differential; Face; Facial Dermatoses; Granuloma, Pyogenic; Humans; Neck; Prognosis; Recurrence; Risk Factors; Skin Neoplasms; Time Factors; United States
PubMed: 15551715
DOI: No ID Found -
Ugeskrift For Laeger Jul 2021Pyogenic granuloma, also known as lobular capillary haemangioma, is a common benign vascular proliferation of not yet fully understood aetiology. Pyogenic granuloma can...
Pyogenic granuloma, also known as lobular capillary haemangioma, is a common benign vascular proliferation of not yet fully understood aetiology. Pyogenic granuloma can occur in all age groups and affect both men and women. Although pyogenic granuloma is a benign lesion, differential diagnosis may include malignant tumours such as amelanotic melanoma, basal cell carcinoma and spindle cell tumour. Surgical excision with primary closure is the usual treatment for pyogenic granuloma/lobular capillary haemangioma and has the lowest rate of recurrence.
Topics: Diagnosis, Differential; Female; Granuloma, Pyogenic; Humans; Male; Melanoma; Neoplasm Recurrence, Local; Skin Neoplasms
PubMed: 34356018
DOI: No ID Found -
Clinical Gastroenterology and... Jul 2021
Topics: Diagnosis, Differential; Duodenum; Granuloma, Pyogenic; Humans
PubMed: 32360803
DOI: 10.1016/j.cgh.2020.04.064 -
Ear, Nose, & Throat Journal Nov 2022
Topics: Ear Auricle; Ear, External; Granuloma, Pyogenic; Hemangioma; Humans
PubMed: 33236929
DOI: 10.1177/0145561320968924 -
Cutis Mar 1995
Review
Topics: Child; Granuloma, Pyogenic; Humans; Skin; Skin Diseases
PubMed: 7634842
DOI: No ID Found -
Indian Journal of Dermatology,... 2019
Review
Topics: Adult; Biopsy, Needle; Follow-Up Studies; Granuloma, Pyogenic; Humans; Immunohistochemistry; Male; Port-Wine Stain; Rare Diseases; Recurrence; Severity of Illness Index; Skin Diseases; Treatment Outcome
PubMed: 29547139
DOI: 10.4103/ijdvl.IJDVL_80_17 -
International Journal of Dermatology Dec 2023
Topics: Humans; Granuloma, Pyogenic; Rituximab
PubMed: 37700737
DOI: 10.1111/ijd.16825